Normal Function

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Greg M Murray - One of the best experts on this subject based on the ideXlab platform.

  • Functional properties of single motor units in the inferior head of human lateral pterygoid muscle: task firing rates.
    Journal of neurophysiology, 2002
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The precise Function of the inferior head of the human lateral pterygoid muscle (IHLP) is unclear. The aim of this study was to clarify the Normal Function of the IHLP. The hypothesis was that an i...

  • Functional properties of single motor units in inferior head of human lateral pterygoid muscle: task relations and thresholds.
    Journal of neurophysiology, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The aim of this study was to clarify the Normal Function of the inferior head of the human lateral pterygoid muscle (IHLP). The hypothesis was that an important Function of the IHLP is in the fine ...

  • a method for standardizing jaw displacements in the horizontal plane while recording single motor unit activity in the human lateral pterygoid muscle
    Journal of Neuroscience Methods, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Shinji Uchida, Sheejith Peeceeyen, Greg M Murray
    Abstract:

    Abstract The Normal Function of the lateral pterygoid muscle is not well understood although this muscle is thought to play an important role in the control of jaw and jaw-joint Function and is implicated in temporomandibular disorders (TMD). The lack of a validated method for standardization of jaw movement in studies of lateral pterygoid Function has contributed to the lack of understanding of the Normal Function of this muscle. An improved understanding of Normal Function will allow valid comparisons to be made with TMD patients in order to identify whether purported differences in activity actually exist. This paper describes a methodology for standardizing command jaw movements in the horizontal plane, together with reliable recordings of single-motor-unit (SMU) activity. In six human participants, jaw movements were standardized by having participants track a linear bank of light-emitting diodes (LEDs) aligned on a monitor displaying the mid-incisor point (MIPT). In all participants, the MIPT target (i.e. an illuminated LED) could be tracked, according to a pre-determined criterion, during single- and multiple-step displacements at different rates (1.3–6.5 mm/s at MIPT) and magnitudes (0.65–12 mm) of movement. SMU activity from the superior (SHLP) or inferior (IHLP) head of the lateral pterygoid muscle could be reliably discriminated during repeated trials of these defined tasks. This methodology establishes a reliable technique for characterizing the firing properties of SMUs within the lateral pterygoid, and has implications for analogous studies in other jaw muscles.

I. Phanachet - One of the best experts on this subject based on the ideXlab platform.

  • Functional properties of single motor units in the inferior head of human lateral pterygoid muscle: task firing rates.
    Journal of neurophysiology, 2002
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The precise Function of the inferior head of the human lateral pterygoid muscle (IHLP) is unclear. The aim of this study was to clarify the Normal Function of the IHLP. The hypothesis was that an i...

  • Functional properties of single motor units in inferior head of human lateral pterygoid muscle: task relations and thresholds.
    Journal of neurophysiology, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The aim of this study was to clarify the Normal Function of the inferior head of the human lateral pterygoid muscle (IHLP). The hypothesis was that an important Function of the IHLP is in the fine ...

  • a method for standardizing jaw displacements in the horizontal plane while recording single motor unit activity in the human lateral pterygoid muscle
    Journal of Neuroscience Methods, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Shinji Uchida, Sheejith Peeceeyen, Greg M Murray
    Abstract:

    Abstract The Normal Function of the lateral pterygoid muscle is not well understood although this muscle is thought to play an important role in the control of jaw and jaw-joint Function and is implicated in temporomandibular disorders (TMD). The lack of a validated method for standardization of jaw movement in studies of lateral pterygoid Function has contributed to the lack of understanding of the Normal Function of this muscle. An improved understanding of Normal Function will allow valid comparisons to be made with TMD patients in order to identify whether purported differences in activity actually exist. This paper describes a methodology for standardizing command jaw movements in the horizontal plane, together with reliable recordings of single-motor-unit (SMU) activity. In six human participants, jaw movements were standardized by having participants track a linear bank of light-emitting diodes (LEDs) aligned on a monitor displaying the mid-incisor point (MIPT). In all participants, the MIPT target (i.e. an illuminated LED) could be tracked, according to a pre-determined criterion, during single- and multiple-step displacements at different rates (1.3–6.5 mm/s at MIPT) and magnitudes (0.65–12 mm) of movement. SMU activity from the superior (SHLP) or inferior (IHLP) head of the lateral pterygoid muscle could be reliably discriminated during repeated trials of these defined tasks. This methodology establishes a reliable technique for characterizing the firing properties of SMUs within the lateral pterygoid, and has implications for analogous studies in other jaw muscles.

Conor L. Evans - One of the best experts on this subject based on the ideXlab platform.

  • longitudinal 3d in vivo imaging of sebaceous glands by coherent anti stokes raman scattering microscopy Normal Function and response to cryotherapy
    Journal of Investigative Dermatology, 2015
    Co-Authors: Yookyung Jung, Rox R Anderson, Ray H Jalian, Conor L. Evans
    Abstract:

    Sebaceous glands perform complex Functions, and they are centrally involved in the pathogenesis of acne vulgaris. Current techniques for studying sebaceous glands are mostly static in nature, whereas the gland’s main Function—excretion of sebum via the holocrine mechanism—can only be evaluated over time. We present a longitudinal, real-time alternative—the in vivo, label-free imaging of sebaceous glands using Coherent Anti-Stokes Raman Scattering (CARS) microscopy, which is used to selectively visualize lipids. In mouse ears, CARS microscopy revealed dynamic changes in sebaceous glands during the holocrine secretion process, as well as in response to damage to the glands caused by cooling. Detailed gland structure, plus the active migration of individual sebocytes and cohorts of sebocytes, were measured. Cooling produced characteristic changes in sebocyte structure and migration. This study demonstrates that CARS microscopy is a promising tool for studying the sebaceous gland and its associated disorders in three dimensions in vivo.

Ray H Jalian - One of the best experts on this subject based on the ideXlab platform.

  • longitudinal 3d in vivo imaging of sebaceous glands by coherent anti stokes raman scattering microscopy Normal Function and response to cryotherapy
    Journal of Investigative Dermatology, 2015
    Co-Authors: Yookyung Jung, Rox R Anderson, Ray H Jalian, Conor L. Evans
    Abstract:

    Sebaceous glands perform complex Functions, and they are centrally involved in the pathogenesis of acne vulgaris. Current techniques for studying sebaceous glands are mostly static in nature, whereas the gland’s main Function—excretion of sebum via the holocrine mechanism—can only be evaluated over time. We present a longitudinal, real-time alternative—the in vivo, label-free imaging of sebaceous glands using Coherent Anti-Stokes Raman Scattering (CARS) microscopy, which is used to selectively visualize lipids. In mouse ears, CARS microscopy revealed dynamic changes in sebaceous glands during the holocrine secretion process, as well as in response to damage to the glands caused by cooling. Detailed gland structure, plus the active migration of individual sebocytes and cohorts of sebocytes, were measured. Cooling produced characteristic changes in sebocyte structure and migration. This study demonstrates that CARS microscopy is a promising tool for studying the sebaceous gland and its associated disorders in three dimensions in vivo.

K. Wanigaratne - One of the best experts on this subject based on the ideXlab platform.

  • Functional properties of single motor units in the inferior head of human lateral pterygoid muscle: task firing rates.
    Journal of neurophysiology, 2002
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The precise Function of the inferior head of the human lateral pterygoid muscle (IHLP) is unclear. The aim of this study was to clarify the Normal Function of the IHLP. The hypothesis was that an i...

  • Functional properties of single motor units in inferior head of human lateral pterygoid muscle: task relations and thresholds.
    Journal of neurophysiology, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Greg M Murray
    Abstract:

    The aim of this study was to clarify the Normal Function of the inferior head of the human lateral pterygoid muscle (IHLP). The hypothesis was that an important Function of the IHLP is in the fine ...

  • a method for standardizing jaw displacements in the horizontal plane while recording single motor unit activity in the human lateral pterygoid muscle
    Journal of Neuroscience Methods, 2001
    Co-Authors: I. Phanachet, Terry Whittle, K. Wanigaratne, Shinji Uchida, Sheejith Peeceeyen, Greg M Murray
    Abstract:

    Abstract The Normal Function of the lateral pterygoid muscle is not well understood although this muscle is thought to play an important role in the control of jaw and jaw-joint Function and is implicated in temporomandibular disorders (TMD). The lack of a validated method for standardization of jaw movement in studies of lateral pterygoid Function has contributed to the lack of understanding of the Normal Function of this muscle. An improved understanding of Normal Function will allow valid comparisons to be made with TMD patients in order to identify whether purported differences in activity actually exist. This paper describes a methodology for standardizing command jaw movements in the horizontal plane, together with reliable recordings of single-motor-unit (SMU) activity. In six human participants, jaw movements were standardized by having participants track a linear bank of light-emitting diodes (LEDs) aligned on a monitor displaying the mid-incisor point (MIPT). In all participants, the MIPT target (i.e. an illuminated LED) could be tracked, according to a pre-determined criterion, during single- and multiple-step displacements at different rates (1.3–6.5 mm/s at MIPT) and magnitudes (0.65–12 mm) of movement. SMU activity from the superior (SHLP) or inferior (IHLP) head of the lateral pterygoid muscle could be reliably discriminated during repeated trials of these defined tasks. This methodology establishes a reliable technique for characterizing the firing properties of SMUs within the lateral pterygoid, and has implications for analogous studies in other jaw muscles.