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Guimarães, Tássia Cecília Pereira - One of the best experts on this subject based on the ideXlab platform.
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Prevalência de alergia alimentar em pré-escolares das escolas municipais de Educação Infantil de Uberlândia/MG
Universidade Federal de Uberlândia, 2014Co-Authors: Guimarães, Tássia Cecília PereiraAbstract:A alergia alimentar é um efeito adverso à saúde, decorrente de alguma resposta imune que ocorre de forma reprodutível sobre a exposição a um dado alimento. Essa alergia tem mostrado aumento expressivo nas últimas décadas, com prevalência estimada em torno de 6 a 8% na faixa etária pediátrica. Embora o alimento causador de alergia alimentar mais frequente seja o leite de vaca, também são comuns alergias desencadeadas por soja, ovo, peixe, amendoim, trigo, milho, arroz e frutos do mar.. A faixa estimada da prevalência de alergia alimentar autorrelatada é de 3% a 35%. Diante disso, o presente estudo pretende conhecer a prevalência de alergia alimentar relatada pelos pais e a diagnosticada por profissionais da saúde, bem como os principais alimentos e manifestações clínicas em pré-escolares matriculados nas Escolas Municipais de Educação Infantil de Uberlândia, Minas Gerais. Com relação aos métodos, trata-se de um estudo epidemiológico transversal, em crianças de 24 a 59 meses, matriculadas nas Escolas Municipais de Educação Infantil de Uberlândia, tendo sido utilizado um questionário autoaplicável para avaliação da prevalência de alergia alimentar relatada pelos pais; posteriormente, as crianças com suspeita de alergia alimentar foram convidadas para uma avaliação clínica e laboratorial, a fim de se conhecer a real prevalência de alergia alimentar. De acordo com os resultados, das 13.841 crianças matriculadas, 8.031 pais responderam ao questionário. A prevalência de alergia alimentar relatada pelos pais foi de 17,6%, e a frequência de asma, rinite e dermatite foi significativamente maior no grupo de crianças com alergia alimentar relatada (p = < 0,0001). Os principais alimentos citados foram leite de vaca, carne suína, frutas, chocolate e ovo de galinha, e os sintomas associados foram manchas vermelhas (54,2%), vômito (39,6%), diarreia (32,1%), dor abdominal (31,4%), edema na boca e nos olhos (17,5%) e secreção no nariz (10,6%). A prevalência de alergia alimentar foi de 0,59% dos pré-escolares, dentre os quais 0,35% apresentaram reações IgE mediadas e 0,24% não IgE mediadas. O ovo foi o principal alérgeno alimentar, atingindo 0,34% dos pré-escolares, seguido por leite de vaca (0,21%), trigo e carne suína (0,06%), milho, mostarda, mel e peixe (0,03%). Os principais sintomas foram: manchas vermelhas e prurido (52,6%), diarreia (42%), edema nos olhos e dor abdominal (36,8%). Concluiu-se que a prevalência de alergia alimentar relatada pelos pais e a prevalência de alergia alimentar confirmada são semelhantes às encontradas na literatura, tendo grande associação com doenças alérgicas (asma, dermatite atópica e rinite alérgica). Os principais alimentos relatados pelos pais confirmam os hábitos alimentares da região pesquisada. Vários estudos descrevem que as influências regionais e culturais interferem nos tipos de alérgenos alimentares. Sendo assim, a maioria dos alimentos associados à alergia alimentar neste estudo, como leite, ovo, trigo, milho, peixe, carne suína, mostarda e mel, foram descritos na literatura mundial. Um número significante de crianças excluiu o alérgeno alimentar sem diagnóstico médico de alergia alimentar.Food allergy is an adverse health effect arising in any immune response that occurs reproducibly on an exposure to a given food. This allergy has shown significant increase in recent decades, with a prevalence estimated around 6-8% in the pediatric age group. Although the most frequent element that causes food allergy is cow milk, allergies triggered by soy, egg, fish, peanuts, wheat, corn, rice and seafood are also possible. The estimated range of self-reported food allergy prevalence is from 3% to 35%. Therefore, this study intends to know the prevalence of reported food allergy diagNosed by parents and that prevalence diagNosed health professionals, as well as major food and clinical manifestations in preschool children enrolled in municipal daycare centers from Uberlândia, Minas Gerais, Brazil. Concerning the methods, it is an epidemiological study in children from 24 to 59 months who were enrolled in municipal daycare centers from Uberlândia, with a self-administered questionnaire that was used to evaluate the prevalence of food allergy related by parents; subsequently, children with a suspecting food allergy were invited to a clinical and laboratory evaluation, in order to know the real prevalence of food allergy. According to the results, from 13,841 children enrolled, 8,031 parents responded the questionnaire. The prevalence of food allergy reported by parents was 17.6%, and the incidence of asthma, rhinitis and dermatitis was significantly higher in the group of children with reported food allergy (p = < 0.0001). The main foods mentioned were cow milk, pork, fruit, chocolate and chicken egg, and associated symptoms were red spots (54.2%), vomit (39.6%), diarrhea (32.1%), abdominal pain (31.4%), mouth and eyes edema (17.5%) and Nose Secretion (10.6%). The prevalence of food allergy was in 0.59% of preschool children, which 0.35% had IgE -mediated reactions and 0.24% non- IgE mediated reactions. The egg was the main food allergen, reaching 0.34% of preschool children, followed by cow milk (0.21%), wheat and pork meat (0.06%), corn, mustard, honey and fish (0.03%). The main symptoms were red spots and itching (52.6%), diarrhea (42%), eyes edema and abdominal pain (36.8%). It was concluded that the prevalence of food allergy reported by parents and confirmed food allergy prevalence are similar to those found in the literature, showing a strong association with allergic diseases (asthma, atopic dermatitis and allergic rhinitis). The main foods reported by parents confirm the eating habits from the researched area. Several studies have reported that regional and cultural influences interfere on the food allergens types. Thus, most of the foods associated with food allergy in this study such as milk, egg, wheat, corn, fish, pork meat, mustard and honey were described in the world literature. A significant number of children excluded food allergen without a medical diagnosis of food allergy
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Prevalência de alergia alimentar em pré-escolares das escolas municipais de Educação Infantil de Uberlândia/MG
'EDUFU - Editora da Universidade Federal de Uberlandia', 2014Co-Authors: Guimarães, Tássia Cecília PereiraAbstract:Food allergy is an adverse health effect arising in any immune response that occurs reproducibly on an exposure to a given food. This allergy has shown significant increase in recent decades, with a prevalence estimated around 6-8% in the pediatric age group. Although the most frequent element that causes food allergy is cow milk, allergies triggered by soy, egg, fish, peanuts, wheat, corn, rice and seafood are also possible. The estimated range of self-reported food allergy prevalence is from 3% to 35%. Therefore, this study intends to know the prevalence of reported food allergy diagNosed by parents and that prevalence diagNosed health professionals, as well as major food and clinical manifestations in preschool children enrolled in municipal daycare centers from Uberlândia, Minas Gerais, Brazil. Concerning the methods, it is an epidemiological study in children from 24 to 59 months who were enrolled in municipal daycare centers from Uberlândia, with a self-administered questionnaire that was used to evaluate the prevalence of food allergy related by parents; subsequently, children with a suspecting food allergy were invited to a clinical and laboratory evaluation, in order to know the real prevalence of food allergy. According to the results, from 13,841 children enrolled, 8,031 parents responded the questionnaire. The prevalence of food allergy reported by parents was 17.6%, and the incidence of asthma, rhinitis and dermatitis was significantly higher in the group of children with reported food allergy (p = < 0.0001). The main foods mentioned were cow milk, pork, fruit, chocolate and chicken egg, and associated symptoms were red spots (54.2%), vomit (39.6%), diarrhea (32.1%), abdominal pain (31.4%), mouth and eyes edema (17.5%) and Nose Secretion (10.6%). The prevalence of food allergy was in 0.59% of preschool children, which 0.35% had IgE -mediated reactions and 0.24% non- IgE mediated reactions. The egg was the main food allergen, reaching 0.34% of preschool children, followed by cow milk (0.21%), wheat and pork meat (0.06%), corn, mustard, honey and fish (0.03%). The main symptoms were red spots and itching (52.6%), diarrhea (42%), eyes edema and abdominal pain (36.8%). It was concluded that the prevalence of food allergy reported by parents and confirmed food allergy prevalence are similar to those found in the literature, showing a strong association with allergic diseases (asthma, atopic dermatitis and allergic rhinitis). The main foods reported by parents confirm the eating habits from the researched area. Several studies have reported that regional and cultural influences interfere on the food allergens types. Thus, most of the foods associated with food allergy in this study such as milk, egg, wheat, corn, fish, pork meat, mustard and honey were described in the world literature. A significant number of children excluded food allergen without a medical diagnosis of food allergy.Mestre em Ciências da SaúdeA alergia alimentar é um efeito adverso à saúde, decorrente de alguma resposta imune que ocorre de forma reprodutível sobre a exposição a um dado alimento. Essa alergia tem mostrado aumento expressivo nas últimas décadas, com prevalência estimada em torno de 6 a 8% na faixa etária pediátrica. Embora o alimento causador de alergia alimentar mais frequente seja o leite de vaca, também são comuns alergias desencadeadas por soja, ovo, peixe, amendoim, trigo, milho, arroz e frutos do mar.. A faixa estimada da prevalência de alergia alimentar autorrelatada é de 3% a 35%. Diante disso, o presente estudo pretende conhecer a prevalência de alergia alimentar relatada pelos pais e a diagnosticada por profissionais da saúde, bem como os principais alimentos e manifestações clínicas em pré-escolares matriculados nas Escolas Municipais de Educação Infantil de Uberlândia, Minas Gerais. Com relação aos métodos, trata-se de um estudo epidemiológico transversal, em crianças de 24 a 59 meses, matriculadas nas Escolas Municipais de Educação Infantil de Uberlândia, tendo sido utilizado um questionário autoaplicável para avaliação da prevalência de alergia alimentar relatada pelos pais; posteriormente, as crianças com suspeita de alergia alimentar foram convidadas para uma avaliação clínica e laboratorial, a fim de se conhecer a real prevalência de alergia alimentar. De acordo com os resultados, das 13.841 crianças matriculadas, 8.031 pais responderam ao questionário. A prevalência de alergia alimentar relatada pelos pais foi de 17,6%, e a frequência de asma, rinite e dermatite foi significativamente maior no grupo de crianças com alergia alimentar relatada (p = < 0,0001). Os principais alimentos citados foram leite de vaca, carne suína, frutas, chocolate e ovo de galinha, e os sintomas associados foram manchas vermelhas (54,2%), vômito (39,6%), diarreia (32,1%), dor abdominal (31,4%), edema na boca e nos olhos (17,5%) e secreção no nariz (10,6%). A prevalência de alergia alimentar foi de 0,59% dos pré-escolares, dentre os quais 0,35% apresentaram reações IgE mediadas e 0,24% não IgE mediadas. O ovo foi o principal alérgeno alimentar, atingindo 0,34% dos pré-escolares, seguido por leite de vaca (0,21%), trigo e carne suína (0,06%), milho, mostarda, mel e peixe (0,03%). Os principais sintomas foram: manchas vermelhas e prurido (52,6%), diarreia (42%), edema nos olhos e dor abdominal (36,8%). Concluiu-se que a prevalência de alergia alimentar relatada pelos pais e a prevalência de alergia alimentar confirmada são semelhantes às encontradas na literatura, tendo grande associação com doenças alérgicas (asma, dermatite atópica e rinite alérgica). Os principais alimentos relatados pelos pais confirmam os hábitos alimentares da região pesquisada. Vários estudos descrevem que as influências regionais e culturais interferem nos tipos de alérgenos alimentares. Sendo assim, a maioria dos alimentos associados à alergia alimentar neste estudo, como leite, ovo, trigo, milho, peixe, carne suína, mostarda e mel, foram descritos na literatura mundial. Um número significante de crianças excluiu o alérgeno alimentar sem diagnóstico médico de alergia alimentar
Rosso Marinela - One of the best experts on this subject based on the ideXlab platform.
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THE EFFECT OF HEAT AND MOISTURE EXCHANGER ON MORPHOLOGICAL AND FUNCTIONAL STATE OF LOVER AIRWAYS IN LARYNGECTOMIZED PERSONS
Josip Juraj Strossmayer University of Osijek. Faculty of Medicine., 2015Co-Authors: Rosso MarinelaAbstract:CILJ ISTRAŽIVANJA: proširenje dosadašnjih spoznaja o terapijskoj vrijednosti i učinkovitosti kazeta za održavanje vlažnosti i temperature zraka čija je uporaba jedini nefarmaceutski način liječenja i prevencije tegoba nastalih nakon totalne laringektomije. NACRT STUDIJE: prospektivna opservacijska studija ISPITANICI I METODE: U studiju je bilo uključeno 70 ispitanika - laringektomiranih osoba obaju spolova liječenih u KBC-u Osijek. Skupinu ispitanika činilo je 35 ispitanika koji se redovito koriste kazetama za održavanje vlažnosti i temperature zraka, a kontrolnu skupinu 35 ispitanika koji se njima ne koriste. Svim ispitanicima uzet je bioptat proksimalnog dijela traheje te su analizirane histološke promjene sluznice. Svi su podvrgnuti spirometriji, a na temelju dobivenih podataka procijenjen je i uspoređen morfološki i funkcionalni status donjih dišnih putova za obje ispitivane skupine. Ispitanici su potom ispunili posebno osmišljen upitnik na osnovi kojega je procijenjen utjecaj kazeta na neke aspekte kvalitete života laringektomiranih osoba. Statistička obrada podataka provedena je pomoću statističkog paketa SPSS (verzija 17.0.0, SPSS Inc., Chicago, IL, SAD). REZULTATI: Blago zadebljanje bazalnih stanica epitela nađeno je u 8 (11 %), srednje zadebljanje bazalnih stanica epitela u 7 (10 %), a jako zadebljanje bazalnih stanica epitela u 2 (3 %) ispitanika. Najveći broj ispitanika imao je nalaz pločaste metaplazije 35 (50 %). Blaga displazija nađena je u 5 (7 %), a umjerena u 4 (6 %) od 70 ispitanika. Postoji statistički značajna razlika u pojavnosti najtežih, prekanceroznih promjena (displazije) u bioptatu sluznice traheje u promatranim skupinama. Displazija I. i II. stupnja nalazi se u 1 (1 %) ispitanika u skupini koja se koristi kazetama, a u 8 (11 %) ispitanika kontrolne skupine. Ispitivani spirometrijski parametri za sve kategorije pokazuju bolji rezultat nalaza u kategoriji ispitanika koji Nose kazetu u usporedbi s onima oni ju koji ne Nose, no ni za jedan parametar nije nađena statistički značajna razlika u ispitivanim skupinama. Svi su ispitanici ocijenili ukupno 10 obilježja vezanih uz dišne putove, osjetilne funkcije i gornji dio probavnog sustava (bol u vratu, problemi vezane uz usnu šupljinu, osjet okusa i mirisa, tegobe s disanjem i nosnom sekrecijom, problemi s gutanjem, govor, kašalj i iskašljavanje). Od ukupno 10 ocijenjenih kategorija, postoji statistički značajna razliku u pojavnosti osjećaja boli u području vrata te osjeta okusa. Od ukupno osam obilježja vezanih uz psihosocijalno funkcioniranje u vlastitom okruženju, statistički značajna razlika nađena je u ocjeni kvalitete komunikacije, socijalne interakcije i koncentracije. ZAKLJUČAK: Kazete za održavanje vlažnosti i temperature zraka mogle bi imati ulogu u očuvanju staničnog integriteta respiratornog epitela. Rezultate spirometrije koji ne pokazuju statistički značajnu razliku za dvije ispitivane skupine moglo bi se pripisati malom uzorku, no ipak predstavljaju značajan temelj za buduća istraživanja. Kazete za održavanje vlažnosti i temperature zraka povoljno utječu na neke simptome koji su uobičajeni nakon totalne laringektomije te na neke aspekte kvalitete života laringektomiranih osoba.OBJECTIVES. Expansion of previous cognitions on therapeutic values and effectiveness of the heat and moisture exchanger as its use is the only non-pharmaceutical way of treatment and prevention of pulmonary complications after total laryngectomy. STUDY DESIGN. Prospective observational study. PATIENTS AND METHODS. The study included 70 respondents – laryngectomized persons of both genders who were treated at Clinical Hospital Center Osijek. There were 35 respondents who regularly used heat and moisture exchangers and 35 respondents in control group who didn't use them. Biopsy specimen of the proximal part of the trachea has been taken in all respondents, and histological changes of the tracheal epithelium have been analysed. All of them have undergone spirometry. According to the obtained data morphological and functional status of lower respiratory tract has been evaluated and compared in both groups of respondents. Subsequently, the respondents have filled in a questionnaire according to which the influence of the heat and moisture exchanger onto some aspects in life quality of patients after laryngectomy could be evaluated. Statistical analysis was performed with SPSS Statistics (Version 17.0.0, SPSS Inc.,Chicago, IL, USA). RESULTS. Mild basal cell hyperplasia has been found in 8 (11 %), moderate basal cell hyperplasia in 7 (10 %), and advanced basal cell hyperplasia in 2 (3 %) respondents. Squamous metaplasia was the most common finding (50 %). Mild dysplasia was found in 5 (7 %), and moderate dysplasia in 4 (6 %) of 70 respondents. There is a statistically significant difference in manifestation of most severe, precancerous changes (dysplasia) in tracheal biopsy specimen in both groups. Mild and moderate squamous dysplasia has been found in 1 (1 %) user, and in 8 (11 %) non-users. Although the examined spirometric parameters for all categories show a better result in experimental group, statistical comparison has not detected any significant differences between the experimental and control group. All respondents graded 10 characteristics connected to respiratory system, sensory functions and the upper part of digestive system (neck pain, dry mouth, taste and smell, breathing problems, Nose Secretion, swallowing problems, speech, cough and expectoration). Out of 10 categories evaluated three were statistically significant difference in neck pain and taste. Out of eight characteristics connected to psychosocial functioning in the environment, statistically significant difference was found in communication, social interaction and concentration. CONCLUSION. Heat and moisture exchanger could have an important role in protection of respiratory epithel cell integrity. Spirometry results which didn't show statistically significant difference for the two examined groups could be explained by small sample, but they represent an important basis for future research. Heat and moisture exchanger positively influences some symptoms that are frequent after total laryngectomy, as well as some aspects of the life quality in patients after total laryngectomy
