The Experts below are selected from a list of 3 Experts worldwide ranked by ideXlab platform
Annarosa Virgili - One of the best experts on this subject based on the ideXlab platform.
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primary cervicofacial nocardiosis due to nocardia asteroides in an adult immunocompetent patient
Acta Dermato-venereologica, 2002Co-Authors: Monica Corazza, Luigi Ligrone, Marco Libanore, Annarosa VirgiliAbstract:Sir, The Nocardia species are aerobic, lamentous grampositive bacteria, irregularly acid-fast staining that belong to the order Actinomycetales. Normally, Nocardia spp. are soil saprophytes, but N. asteroides may be found in the normal ora of the oral cavity and upper respiratory tract. Four species of Nocardia are pathogenic in man: N. asteroides, N. brasiliensis, N. caviae and N. madurae (1). N. asteroides is usually the agent of systemic pulmonary infections in immunocompromised hosts, while N. brasiliensis is the responsible agent in 74% of all cutaneous manifestations (1, 2). The skin is generally secondarily involved in disseminated systemic pulmonary diseases, due to haematogenous spread of N. asteroides, but it can also be primarily aVected. Primary cutaneous nocardiosis (PCN) accounts for only 5% of all nocardial infections and is caused mainly by N. brasiliensis (3, 4). PCN is characterized by numerFig. 1. In ammatory and Ulcerative lesion of the Nose. ous clinical manifestations: chronic mycetoma, super cial abscesses and cellulitis and lymphocutaneous increased ESR (93mm/h). Paraneoplastic serological variants. The last of these manifestations includes the markers, immunological investigations and HIV-1/2 more common sporotrichoid form (nodules along the serology were negative. Hemocultures were also lymphatic drainage) and the rarer cervicofacial variant. negative. We report an unusual case of primary cervicofacial Skull and chest X-rays were negative while ultrasononocardiosis caused by N. asteroides in an adult graphy revealed gross hypoecogenic non-homogeneous immunocompetent man. areas (colliquated lymph nodes) extending to the subfascial area. Sonography also showed numerous colliquated CASE REPORT lymph nodes in the right laterocervical region as well as a colliquative involvement of both the parotides and A 79-year-old man was admitted to our department because of fever and a necrotic Ulcerative lesion of the submandibular lymph nodes. Computerized axial tomography of the head con rmed all the data and again dorsum of his Nose. The borders were vegetant, in ltrated on palpation and a purulent exudate was easily showed abscesses of the left masseter muscle and the left submandibular salivary gland. obtained through compression. Numerous sparse tiny pustules and little pus-draining sinuses were peripherHistology of a skin biopsy taken from the borders of the Ulcer only revealed a dense diVuse in ammatory ically sparse around the Ulcerative lesion (Fig. 1). The in ammatory oedema involved the left cheek and the in ltrate of neutrophils and lymphocytes in the deep dermis, with abscess formation. No fungic elements were lower eyelid. A hardened swelling of the left mandibular angle and some hard, enlarged, latero-cervical lymph observed with PAS staining. Endovenous therapy with amoxicillin/clavulanic acid nodes were present. History revealed that the patient had had a bicycle 6.6 g/day, amikacin 1 g/day and teicoplanin 800mg/day was immediately started. A week later a slight improveaccident 15 days earlier, causing wounds on his forehead, Nose and left cheek. The wounds had healed rapidly ment of the purulent and in ammatory aspects of the facial lesions was observed but the laterocervical tumewith common antiseptic medications. Blood sample examination revealed white blood factions had worsened and required surgical drainage. Cultures of purulent exudate from the Nose Ulcer, cells 13 109/l (60% neutrophils, 25% monocytes) and
Monica Corazza - One of the best experts on this subject based on the ideXlab platform.
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primary cervicofacial nocardiosis due to nocardia asteroides in an adult immunocompetent patient
Acta Dermato-venereologica, 2002Co-Authors: Monica Corazza, Luigi Ligrone, Marco Libanore, Annarosa VirgiliAbstract:Sir, The Nocardia species are aerobic, lamentous grampositive bacteria, irregularly acid-fast staining that belong to the order Actinomycetales. Normally, Nocardia spp. are soil saprophytes, but N. asteroides may be found in the normal ora of the oral cavity and upper respiratory tract. Four species of Nocardia are pathogenic in man: N. asteroides, N. brasiliensis, N. caviae and N. madurae (1). N. asteroides is usually the agent of systemic pulmonary infections in immunocompromised hosts, while N. brasiliensis is the responsible agent in 74% of all cutaneous manifestations (1, 2). The skin is generally secondarily involved in disseminated systemic pulmonary diseases, due to haematogenous spread of N. asteroides, but it can also be primarily aVected. Primary cutaneous nocardiosis (PCN) accounts for only 5% of all nocardial infections and is caused mainly by N. brasiliensis (3, 4). PCN is characterized by numerFig. 1. In ammatory and Ulcerative lesion of the Nose. ous clinical manifestations: chronic mycetoma, super cial abscesses and cellulitis and lymphocutaneous increased ESR (93mm/h). Paraneoplastic serological variants. The last of these manifestations includes the markers, immunological investigations and HIV-1/2 more common sporotrichoid form (nodules along the serology were negative. Hemocultures were also lymphatic drainage) and the rarer cervicofacial variant. negative. We report an unusual case of primary cervicofacial Skull and chest X-rays were negative while ultrasononocardiosis caused by N. asteroides in an adult graphy revealed gross hypoecogenic non-homogeneous immunocompetent man. areas (colliquated lymph nodes) extending to the subfascial area. Sonography also showed numerous colliquated CASE REPORT lymph nodes in the right laterocervical region as well as a colliquative involvement of both the parotides and A 79-year-old man was admitted to our department because of fever and a necrotic Ulcerative lesion of the submandibular lymph nodes. Computerized axial tomography of the head con rmed all the data and again dorsum of his Nose. The borders were vegetant, in ltrated on palpation and a purulent exudate was easily showed abscesses of the left masseter muscle and the left submandibular salivary gland. obtained through compression. Numerous sparse tiny pustules and little pus-draining sinuses were peripherHistology of a skin biopsy taken from the borders of the Ulcer only revealed a dense diVuse in ammatory ically sparse around the Ulcerative lesion (Fig. 1). The in ammatory oedema involved the left cheek and the in ltrate of neutrophils and lymphocytes in the deep dermis, with abscess formation. No fungic elements were lower eyelid. A hardened swelling of the left mandibular angle and some hard, enlarged, latero-cervical lymph observed with PAS staining. Endovenous therapy with amoxicillin/clavulanic acid nodes were present. History revealed that the patient had had a bicycle 6.6 g/day, amikacin 1 g/day and teicoplanin 800mg/day was immediately started. A week later a slight improveaccident 15 days earlier, causing wounds on his forehead, Nose and left cheek. The wounds had healed rapidly ment of the purulent and in ammatory aspects of the facial lesions was observed but the laterocervical tumewith common antiseptic medications. Blood sample examination revealed white blood factions had worsened and required surgical drainage. Cultures of purulent exudate from the Nose Ulcer, cells 13 109/l (60% neutrophils, 25% monocytes) and
Luigi Ligrone - One of the best experts on this subject based on the ideXlab platform.
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primary cervicofacial nocardiosis due to nocardia asteroides in an adult immunocompetent patient
Acta Dermato-venereologica, 2002Co-Authors: Monica Corazza, Luigi Ligrone, Marco Libanore, Annarosa VirgiliAbstract:Sir, The Nocardia species are aerobic, lamentous grampositive bacteria, irregularly acid-fast staining that belong to the order Actinomycetales. Normally, Nocardia spp. are soil saprophytes, but N. asteroides may be found in the normal ora of the oral cavity and upper respiratory tract. Four species of Nocardia are pathogenic in man: N. asteroides, N. brasiliensis, N. caviae and N. madurae (1). N. asteroides is usually the agent of systemic pulmonary infections in immunocompromised hosts, while N. brasiliensis is the responsible agent in 74% of all cutaneous manifestations (1, 2). The skin is generally secondarily involved in disseminated systemic pulmonary diseases, due to haematogenous spread of N. asteroides, but it can also be primarily aVected. Primary cutaneous nocardiosis (PCN) accounts for only 5% of all nocardial infections and is caused mainly by N. brasiliensis (3, 4). PCN is characterized by numerFig. 1. In ammatory and Ulcerative lesion of the Nose. ous clinical manifestations: chronic mycetoma, super cial abscesses and cellulitis and lymphocutaneous increased ESR (93mm/h). Paraneoplastic serological variants. The last of these manifestations includes the markers, immunological investigations and HIV-1/2 more common sporotrichoid form (nodules along the serology were negative. Hemocultures were also lymphatic drainage) and the rarer cervicofacial variant. negative. We report an unusual case of primary cervicofacial Skull and chest X-rays were negative while ultrasononocardiosis caused by N. asteroides in an adult graphy revealed gross hypoecogenic non-homogeneous immunocompetent man. areas (colliquated lymph nodes) extending to the subfascial area. Sonography also showed numerous colliquated CASE REPORT lymph nodes in the right laterocervical region as well as a colliquative involvement of both the parotides and A 79-year-old man was admitted to our department because of fever and a necrotic Ulcerative lesion of the submandibular lymph nodes. Computerized axial tomography of the head con rmed all the data and again dorsum of his Nose. The borders were vegetant, in ltrated on palpation and a purulent exudate was easily showed abscesses of the left masseter muscle and the left submandibular salivary gland. obtained through compression. Numerous sparse tiny pustules and little pus-draining sinuses were peripherHistology of a skin biopsy taken from the borders of the Ulcer only revealed a dense diVuse in ammatory ically sparse around the Ulcerative lesion (Fig. 1). The in ammatory oedema involved the left cheek and the in ltrate of neutrophils and lymphocytes in the deep dermis, with abscess formation. No fungic elements were lower eyelid. A hardened swelling of the left mandibular angle and some hard, enlarged, latero-cervical lymph observed with PAS staining. Endovenous therapy with amoxicillin/clavulanic acid nodes were present. History revealed that the patient had had a bicycle 6.6 g/day, amikacin 1 g/day and teicoplanin 800mg/day was immediately started. A week later a slight improveaccident 15 days earlier, causing wounds on his forehead, Nose and left cheek. The wounds had healed rapidly ment of the purulent and in ammatory aspects of the facial lesions was observed but the laterocervical tumewith common antiseptic medications. Blood sample examination revealed white blood factions had worsened and required surgical drainage. Cultures of purulent exudate from the Nose Ulcer, cells 13 109/l (60% neutrophils, 25% monocytes) and
Marco Libanore - One of the best experts on this subject based on the ideXlab platform.
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primary cervicofacial nocardiosis due to nocardia asteroides in an adult immunocompetent patient
Acta Dermato-venereologica, 2002Co-Authors: Monica Corazza, Luigi Ligrone, Marco Libanore, Annarosa VirgiliAbstract:Sir, The Nocardia species are aerobic, lamentous grampositive bacteria, irregularly acid-fast staining that belong to the order Actinomycetales. Normally, Nocardia spp. are soil saprophytes, but N. asteroides may be found in the normal ora of the oral cavity and upper respiratory tract. Four species of Nocardia are pathogenic in man: N. asteroides, N. brasiliensis, N. caviae and N. madurae (1). N. asteroides is usually the agent of systemic pulmonary infections in immunocompromised hosts, while N. brasiliensis is the responsible agent in 74% of all cutaneous manifestations (1, 2). The skin is generally secondarily involved in disseminated systemic pulmonary diseases, due to haematogenous spread of N. asteroides, but it can also be primarily aVected. Primary cutaneous nocardiosis (PCN) accounts for only 5% of all nocardial infections and is caused mainly by N. brasiliensis (3, 4). PCN is characterized by numerFig. 1. In ammatory and Ulcerative lesion of the Nose. ous clinical manifestations: chronic mycetoma, super cial abscesses and cellulitis and lymphocutaneous increased ESR (93mm/h). Paraneoplastic serological variants. The last of these manifestations includes the markers, immunological investigations and HIV-1/2 more common sporotrichoid form (nodules along the serology were negative. Hemocultures were also lymphatic drainage) and the rarer cervicofacial variant. negative. We report an unusual case of primary cervicofacial Skull and chest X-rays were negative while ultrasononocardiosis caused by N. asteroides in an adult graphy revealed gross hypoecogenic non-homogeneous immunocompetent man. areas (colliquated lymph nodes) extending to the subfascial area. Sonography also showed numerous colliquated CASE REPORT lymph nodes in the right laterocervical region as well as a colliquative involvement of both the parotides and A 79-year-old man was admitted to our department because of fever and a necrotic Ulcerative lesion of the submandibular lymph nodes. Computerized axial tomography of the head con rmed all the data and again dorsum of his Nose. The borders were vegetant, in ltrated on palpation and a purulent exudate was easily showed abscesses of the left masseter muscle and the left submandibular salivary gland. obtained through compression. Numerous sparse tiny pustules and little pus-draining sinuses were peripherHistology of a skin biopsy taken from the borders of the Ulcer only revealed a dense diVuse in ammatory ically sparse around the Ulcerative lesion (Fig. 1). The in ammatory oedema involved the left cheek and the in ltrate of neutrophils and lymphocytes in the deep dermis, with abscess formation. No fungic elements were lower eyelid. A hardened swelling of the left mandibular angle and some hard, enlarged, latero-cervical lymph observed with PAS staining. Endovenous therapy with amoxicillin/clavulanic acid nodes were present. History revealed that the patient had had a bicycle 6.6 g/day, amikacin 1 g/day and teicoplanin 800mg/day was immediately started. A week later a slight improveaccident 15 days earlier, causing wounds on his forehead, Nose and left cheek. The wounds had healed rapidly ment of the purulent and in ammatory aspects of the facial lesions was observed but the laterocervical tumewith common antiseptic medications. Blood sample examination revealed white blood factions had worsened and required surgical drainage. Cultures of purulent exudate from the Nose Ulcer, cells 13 109/l (60% neutrophils, 25% monocytes) and
