The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
M Ichihashib - One of the best experts on this subject based on the ideXlab platform.
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mercury induced Nummular Dermatitis
Journal of The American Academy of Dermatology, 2000Co-Authors: Atsuko Adachia, T Horikawab, T Takashimac, M IchihashibAbstract:Abstract We report 2 cases of relapsing Nummular Dermatitis according to mercury sensitivity, which was confirmed by patch testing. Removal of the amalgam from dental metal alloys markedly improved their skin eruptions. One of the patients, a dentist, experienced exacerbation of the eruptions on his lower legs after handling dental amalgam. Hypersensitivity to haptens such as metals is possibly involved in, at least in some patients, the pathogenesis of Nummular Dermatitis. (J Am Acad Dermatol 2000;43:383-5.)
Atsuko Adachia - One of the best experts on this subject based on the ideXlab platform.
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mercury induced Nummular Dermatitis
Journal of The American Academy of Dermatology, 2000Co-Authors: Atsuko Adachia, T Horikawab, T Takashimac, M IchihashibAbstract:Abstract We report 2 cases of relapsing Nummular Dermatitis according to mercury sensitivity, which was confirmed by patch testing. Removal of the amalgam from dental metal alloys markedly improved their skin eruptions. One of the patients, a dentist, experienced exacerbation of the eruptions on his lower legs after handling dental amalgam. Hypersensitivity to haptens such as metals is possibly involved in, at least in some patients, the pathogenesis of Nummular Dermatitis. (J Am Acad Dermatol 2000;43:383-5.)
Fukumi Furukawa - One of the best experts on this subject based on the ideXlab platform.
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Therapeutic effects of antibacterial treatment for intractable skin diseases in Helicobacter pylori-positive Japanese patients.
Journal of Dermatology, 2014Co-Authors: Mikihisa Sakurane, Akiko Shiotani, Fukumi FurukawaAbstract:Abstract In order to understand the pathogenic relationship between Helicobacter pylori (H. pylori) and skin diseases, we examined the serum levels of IgG antibody against H. pylori and then performed gastroscopic examinations in Japanese patients with chronic skin diseases. These H. prylori-positive patients were treated with antibacterial eradication therapy, and therapeutic efficacy was evaluated. A total of 198 patients who were resistant to conventional therapies were randomly selected. They included 50 cases with chronic urticaria, 32 with pruritus cutaneous, 74 with atopic Dermatitis, 15 with Nummular Dermatitis, 17 with prurigo chronica multiformis, 6 with psoriasis vulgaris, and 4 with erythroderma. Positive anti-H. pylori antibody was detected in 102 out of these 198 patients; more than half of the ones with chronic urticaria, pruritus cutaneous, Nummular Dermatitis, and prurigo chronica multiformis had positive antibodies. Gastroscopy was then performed in 48 cases with positive antibodies. Eradication therapy was effective in 60% of the patients with chronic urticaria, in 58% with pruritus cutaneous, in 54% with Nummular Dermatitis, and in 50% with prurigo chronica multiformis. In chronic skin diseases, persistent infection with H. pylori may be an eruption trigger and may cause deterioration of the disease into an in tractable and chronic form.
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Helicobacter pylori-positive patients with pruritic skin diseases are at increased risk for gastric cancer.
Alimentary Pharmacology & Therapeutics, 2004Co-Authors: Akiko Shiotani, Mikihisa Sakurane, Fukumi FurukawaAbstract:Background: Helicobacter pylori infection has been implicated as a possible cause of extraintestinal disorders such as skin diseases. A number of case reports describe patients with skin diseases, such as prurigo nodularis, that are associated with gastric cancer. Aim: The aim of this study was to examine the prevalence of H. pylori infection and the incidence of gastric cancer in patients with pruritic skin diseases. Methods: The patients were examined for circulating specific IgG antibodies against H. pylori in sera using ELISA. H. pylori-positive patients who were more than 40 years old underwent endoscopic screening for gastric cancer. Results: We examined 134 patients with pruritic skin diseases, including 55 cases of cutaneous pruritus, 21 cases of prurigo chronica multiforme, 15 cases of Nummular Dermatitis and 43 cases of chronic urticaria. Early gastric cancer was detected in 2/36 (5.6%) patients with cutaneous pruritus and 3/16 (18.8%) with prurigo chronica multiforme. The prevalence of early gastric cancer was 5.6%, which was much higher than that among patients undergoing general endoscopic screening for gastric cancer. Conclusions: These results suggest that H. pylori-positive patients with pruritic skin diseases may be at increased risk for development of gastric cancer, and endoscopic screening in such patients is recommended.
T Horikawab - One of the best experts on this subject based on the ideXlab platform.
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mercury induced Nummular Dermatitis
Journal of The American Academy of Dermatology, 2000Co-Authors: Atsuko Adachia, T Horikawab, T Takashimac, M IchihashibAbstract:Abstract We report 2 cases of relapsing Nummular Dermatitis according to mercury sensitivity, which was confirmed by patch testing. Removal of the amalgam from dental metal alloys markedly improved their skin eruptions. One of the patients, a dentist, experienced exacerbation of the eruptions on his lower legs after handling dental amalgam. Hypersensitivity to haptens such as metals is possibly involved in, at least in some patients, the pathogenesis of Nummular Dermatitis. (J Am Acad Dermatol 2000;43:383-5.)
T Takashimac - One of the best experts on this subject based on the ideXlab platform.
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mercury induced Nummular Dermatitis
Journal of The American Academy of Dermatology, 2000Co-Authors: Atsuko Adachia, T Horikawab, T Takashimac, M IchihashibAbstract:Abstract We report 2 cases of relapsing Nummular Dermatitis according to mercury sensitivity, which was confirmed by patch testing. Removal of the amalgam from dental metal alloys markedly improved their skin eruptions. One of the patients, a dentist, experienced exacerbation of the eruptions on his lower legs after handling dental amalgam. Hypersensitivity to haptens such as metals is possibly involved in, at least in some patients, the pathogenesis of Nummular Dermatitis. (J Am Acad Dermatol 2000;43:383-5.)
