The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
Sayantanava Mitra - One of the best experts on this subject based on the ideXlab platform.
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Inside the mind of poor Tom – A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research-neuroimaging, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
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Inside the mind of poor Tom - A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
Tathagata Mahintamani - One of the best experts on this subject based on the ideXlab platform.
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Inside the mind of poor Tom – A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research-neuroimaging, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
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Inside the mind of poor Tom - A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
Daya Ram - One of the best experts on this subject based on the ideXlab platform.
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Inside the mind of poor Tom – A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research-neuroimaging, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
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Inside the mind of poor Tom - A multidimensional approach to determine causes for redundant clothing in patients with schizophrenia
Psychiatry Research, 2015Co-Authors: Tathagata Mahintamani, Daya Ram, Sayantanava MitraAbstract:Redundant clothing (RC) is a readily Observable Feature of schizophrenia. While abnormal thermoregulation, thyroid dysfunction and autonomic dysregulation have been postulated to account for RC, no identified factor yet conclusively explains this enigmatic behaviour. This study attempted to determine the cause(s) of RC in schizophrenia. Two groups of 20 age- and sex-matched patients with and without RC were studied. Socio-demographic and clinical characteristics were recorded, and patients were assessed for psychopathology (Positive and Negative Syndrome Scale (PANSS)), cognitive function (Schizophrenia Cognition Rating Scale (SCoRS)), and autonomic and thyroid function. Those with RC differed significantly from those without RC in education, occupation, marital status and duration of untreated psychosis (DUP). They were more disorganised, more withdrawn, and had significant affective impairment. The RC group also had significantly higher negative, general and total psychopathology scores on the Positive and Negative Syndrome Scale, significantly poorer cognitive function, greater autonomic dysfunction, and lower free T3 and free T4 concentrations. We propose that the dimension of RC could define a subgroup with poorer premorbid functioning and a longer DUP, in whom cognitive dysfunction and prominent negative symptoms coloured the manifestations of deranged thermoregulation secondary to lower thyroid hormone levels and autonomic dysfunction, ultimately resulting in redundant clothing.
Mikhail B Voloshin - One of the best experts on this subject based on the ideXlab platform.
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A gamma-ray signature of energetic sources of cosmic-ray nuclei
Physics Letters B, 2012Co-Authors: Alexander Kusenko, Mikhail B VoloshinAbstract:Abstract Astrophysical sources of nuclei are expected to produce a broad spectrum of isotopes, many of which are unstable. An unstable nucleus can beta-decay outside the source into a single-electron ion. Heavy one-electron ions, thus formed, can be excited in their interactions with cosmic microwave background photons, in which case they relax to the ground state with the emission of a gamma ray. Repetitive cycles of excitation and gamma-ray emission can produce an Observable Feature in the gamma-ray spectrum with a maximum around 8 GeV (for iron). We find that the observed spectrum of Centaurus A is consistent with a substantial flux of nuclei accelerated to 0.1 EeV. A characteristic 5–10 GeV (iron) shoulder in the gamma-ray spectra of various sources can help identify astrophysical accelerators of nuclei or set upper limits on nuclear acceleration.
Alexander Kusenko - One of the best experts on this subject based on the ideXlab platform.
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A gamma-ray signature of energetic sources of cosmic-ray nuclei
Physics Letters B, 2012Co-Authors: Alexander Kusenko, Mikhail B VoloshinAbstract:Abstract Astrophysical sources of nuclei are expected to produce a broad spectrum of isotopes, many of which are unstable. An unstable nucleus can beta-decay outside the source into a single-electron ion. Heavy one-electron ions, thus formed, can be excited in their interactions with cosmic microwave background photons, in which case they relax to the ground state with the emission of a gamma ray. Repetitive cycles of excitation and gamma-ray emission can produce an Observable Feature in the gamma-ray spectrum with a maximum around 8 GeV (for iron). We find that the observed spectrum of Centaurus A is consistent with a substantial flux of nuclei accelerated to 0.1 EeV. A characteristic 5–10 GeV (iron) shoulder in the gamma-ray spectra of various sources can help identify astrophysical accelerators of nuclei or set upper limits on nuclear acceleration.
