The Experts below are selected from a list of 685347 Experts worldwide ranked by ideXlab platform
Frank D Kolodgie - One of the best experts on this subject based on the ideXlab platform.
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pathology of second generation everolimus eluting stents versus first generation sirolimus and paclitaxel eluting stents in humans
Circulation, 2014Co-Authors: Fumiyuki Otsuka, Marc Vorpahl, Masataka Nakano, Jason Foerst, John B Newell, Kenichi Sakakura, Robert Kutys, Elena Ladich, Aloke V Finn, Frank D KolodgieAbstract:Background—Clinical trials have demonstrated that the second-generation cobalt-chromium everolimus-eluting stent (CoCr-EES) is superior to the first-generation paclitaxel-eluting stent (PES) and is noninferior or superior to the sirolimus-eluting stent (SES) in terms of safety and efficacy. It remains unclear whether vascular responses to CoCr-EES are different from those to SES and PES because the pathology of CoCr-EES has not been described in humans. Methods and Results—A total of 204 lesions (SES=73; PES=85; CoCr-EES=46) from 149 autopsy cases with duration of implantation >30 days and ≤3 years were pathologically analyzed, and comparison of vascular responses was corrected for duration of implantation. The Observed Frequency of late and very late stent thrombosis was less in CoCr-EES (4%) versus SES (21%; P=0.029) and PES (26%; P=0.008). Neointimal thickness was comparable among the groups, whereas the percentage of uncovered struts was strikingly lower in CoCr-EES (median=2.6%) versus SES (18.0%; P<...
S Brazovskii - One of the best experts on this subject based on the ideXlab platform.
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on origin of the low temperature low Frequency dielectric susceptibility peak in charge and spin density waves
Solid State Communications, 1995Co-Authors: A I Larkin, S BrazovskiiAbstract:Abstract We suggest a theory for the recently Observed Frequency dependent low temperature anomaly of the dielectric susceptibility ɛ in Charge and Spin Density Waves, emphasizing interference of collective and local type of pinning. The local pinning is characterized by metastable plastic deformations: neutral bisolitons or pairs of dislocation loops. The weak collective pinning is governed by the elasticity hardening due to Coulomb interaction.
Yoshifumi Kimura - One of the best experts on this subject based on the ideXlab platform.
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solute solvent hydrogen bonding in room temperature ionic liquids studied by raman spectroscopy
Physical Chemistry Chemical Physics, 2012Co-Authors: Akira Kobayashi, Koji Osawa, Masahide Terazima, Yoshifumi KimuraAbstract:The vibrational frequencies of the CO + CC band of diphenylcyclopropenone and the NH2 stretching band of p-aminobenzonitrile were determined in various room temperature ionic liquids (RTILs). The vibrational Frequency shifts of the CO + CC stretching mode were compared with Kamlet α values, and Frequency shifts of the NH2 stretching mode were compared with Kamlet β values. A nearly linear relationship was obtained for both parameters, although the solvatochromic parameters were more sensitive to changes of the cation species. Vibrational Frequency calculations of a 1 : 1 cluster of p-aminobenzonitrile with the RTIL anions using DFT theory reproduced the Observed Frequency shifts of the NH2 stretching mode fairly well. The Frequency shifts of the CN stretching mode were well reproduced by the linear combination of dipolarity parameters, the hydrogen-bond donating and accepting parameters determined by the Raman shift of the solute molecule.
Fumiyuki Otsuka - One of the best experts on this subject based on the ideXlab platform.
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pathology of second generation everolimus eluting stents versus first generation sirolimus and paclitaxel eluting stents in humans
Circulation, 2014Co-Authors: Fumiyuki Otsuka, Marc Vorpahl, Masataka Nakano, Jason Foerst, John B Newell, Kenichi Sakakura, Robert Kutys, Elena Ladich, Aloke V Finn, Frank D KolodgieAbstract:Background—Clinical trials have demonstrated that the second-generation cobalt-chromium everolimus-eluting stent (CoCr-EES) is superior to the first-generation paclitaxel-eluting stent (PES) and is noninferior or superior to the sirolimus-eluting stent (SES) in terms of safety and efficacy. It remains unclear whether vascular responses to CoCr-EES are different from those to SES and PES because the pathology of CoCr-EES has not been described in humans. Methods and Results—A total of 204 lesions (SES=73; PES=85; CoCr-EES=46) from 149 autopsy cases with duration of implantation >30 days and ≤3 years were pathologically analyzed, and comparison of vascular responses was corrected for duration of implantation. The Observed Frequency of late and very late stent thrombosis was less in CoCr-EES (4%) versus SES (21%; P=0.029) and PES (26%; P=0.008). Neointimal thickness was comparable among the groups, whereas the percentage of uncovered struts was strikingly lower in CoCr-EES (median=2.6%) versus SES (18.0%; P<...
Franklin E Leach - One of the best experts on this subject based on the ideXlab platform.
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analysis of phase dependent Frequency shifts in simulated ftms transients using the filter diagonalization method
International Journal of Mass Spectrometry, 2012Co-Authors: Franklin E Leach, Konstantin Aizikov, Peter B Oconnor, Andriy Kharchenko, Gleb Vladimirov, Ron M A Heeren, Eugene N. Nikolaev, Jonathan I AmsterAbstract:Abstract Space-charge perturbs ion motion and affects mass accuracy in ion trapping mass spectrometers. In Fourier transform mass spectrometry (FTMS), both ion–ion and ion–image charge interactions have been examined by experiments and by multiparticle ion simulations using the particle-in-cell (PIC) approach, and the magnitude of Observed Frequency shifts as a function of ion number agrees with theoretical models. Frequency shifts due to ion–ion interactions have generally been treated in a time-integrated fashion, that is, for the duration of the transient signal. Aizikov and O’Connor have experimentally shown that there is a time-dependence for such interactions, with a periodicity that correlates to the beat period between isotope peaks. Here, we investigate such interactions using PIC simulations and the filter diagonalization method (FDM) for obtaining frequencies from very short durations of the transient. Periodic decreases in Observed Frequency correlate with ion clouds of isotope peaks coming into phase in their cyclotron orbit. A similar phenomenon is Observed in the simulations of ion motion in an Orbitrap mass analyzer, corresponding to the axial motion of isotope groupings moving in and out of phase.
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Comparison of particle-in-cell simulations with experimentally Observed Frequency shifts between ions of the same mass-to-charge in fourier transform ion cyclotron resonance mass spectrometry
Journal of the American Society for Mass Spectrometry, 2010Co-Authors: Franklin E Leach, Andriy Kharchenko, Ron M A Heeren, Eugene Nikolaev, I. Jonathan AmsterAbstract:It has been previously Observed that the measured Frequency of ions in a Fourier transform mass spectrometry experiment depend upon the number of trapped ions, even for populations consisting exclusively of a single mass-to-charge. Since ions of the same mass-to-charge are thought not to exert a space-charge effect among themselves, the experimental observation of such Frequency shifts raises questions about their origin. To determine the source of such experimentally Observed Frequency shifts, multiparticle ion trajectory simulations have been conducted on monoisotopic populations of Cs^+ ranging from 10^2 ions to 10^6 ions. A close match to experimental behavior is Observed. By probing the effect of ion number and orbital radius on the shift in the cyclotron Frequency, it is shown that for a monoisotopic population of ions, the Frequency shift is caused by the interaction of ions with their image-charge. The addition of ions of a second mass-to-charge to the simulation allows the comparison of the magnitude of the Frequency shift resulting from space-charge (ion-ion) effects versus ion interactions with their image charge.
