The Experts below are selected from a list of 22047 Experts worldwide ranked by ideXlab platform
James R Sheller - One of the best experts on this subject based on the ideXlab platform.
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use of pulse oximetry to recognize severity of airflow obstruction in Obstructive Airway Disease correlation with pulsus paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
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Clinical Investigations in Critical CareUse of Pulse Oximetry to Recognize Severity of Airflow Obstruction in Obstructive Airway Disease: Correlation With Pulsus Paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
Susan Redline - One of the best experts on this subject based on the ideXlab platform.
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sleep apnea and Obstructive Airway Disease in older men outcomes of sleep disorders in older men study
Sleep, 2016Co-Authors: Ying Y Zhao, Terri Blackwell, Kristine E Ensrud, Katie L Stone, Theodore A Omachi, Susan RedlineAbstract:STUDY OBJECTIVES To evaluate the association between Obstructive Airway Disease (OAD) and sleep apnea in older men. METHODS A community-based cross-sectional study of 853 community-dwelling older men (mean age 80.7 ± 4.1 years [range 73 to 90]) across 6 centers in the United States from the Outcomes of Sleep Disorders in Older Men Study. Sleep was objectively measured using full in-home polysomnography and lung function was objectively measured using spirometry. The association of OAD (pre-bronchodilator FEV1/FVC ratio < 0.7 and FEV1 < 80% predicted) and sleep apnea (apnea-hypopnea index [AHI] ≥ 15 events/hour) was assessed using logistic regression. RESULTS OAD and sleep apnea were identified in 111 (13.0%) and 247 (29.0%) men, respectively. In univariate analysis, participants with OAD had a lower AHI (mean ± SD; 8.7 ± 11.7 vs. 12.7 ± 13.8, P = 0.0009) and a lower prevalence of sleep apnea (14.4 vs. 31.1%, P = 0.0003) compared to participants without OAD. OAD remained independently associated with a lower odds of sleep apnea (odds ratio 0.30, 95% CI 0.16 to 0.55, P = 0.0001) after adjustment for demographics, body composition, smoking, and potential mediators (arousal index, time spent in rapid eye movement sleep). Individuals with OAD and sleep apnea (n = 16) had an increased arousal index and lower oxygen saturation level as compared to individuals with OAD alone (P values < 0.05). CONCLUSIONS Obstructive Airway Disease was associated with a lower prevalence of sleep apnea in a cohort of community-dwelling elderly men, and unexplained by differences in adiposity or sleep architecture. Although uncommon in this cohort, coexisting sleep apnea and OAD was associated with increased sleep fragmentation and nocturnal oxygen desaturation compared to OAD alone.
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sleep and sleep disordered breathing in adults with predominantly mild Obstructive Airway Disease
American Journal of Respiratory and Critical Care Medicine, 2003Co-Authors: Mark H Sanders, Susan Redline, Anne B Newman, Michael D. Lebowitz, Catherine L Haggerty, Jonathan M Samet, George T Oconnor, Naresh M Punjabi, Eyal ShaharAbstract:Neither the association between Obstructive Airways Disease (OAD) and sleep apnea-hypopnea (SAH) nor the sleep consequences of each disorder alone and together have been characterized in an adult community setting. Our primary aims were (1) to determine if there is an association between OAD and SAH and (2) identify predictors of oxyhemoglobin desaturation during sleep in persons having OAD with and without SAH. Polysomnography and spirometry results from 5,954 participants in the Sleep Heart Health Study were analyzed. OAD was defined by a FEV1/FVC value less than 70%. Assessment of SAH prevalence in OAD was performed using thresholds of respiratory disturbance index (RDI) greater than 10 and greater than 15. A total of 1,132 participants had OAD that was predominantly mild (FEV1/FVC 63.81 +/- 6.56%, mean +/- SD). SAH was not more prevalent in participants with OAD than in those without OAD (22.32 versus 28.86%, with and without OAD, respectively, at RDI threshold values greater than 10; and 13.97 versus 18.63%, with and without OAD, respectively, at RDI threshold value greater than 15). In the absence of SAH, the adjusted odds ratio for sleep desaturation (> 5% total sleep time with saturation < 90%) was greater than 1.9 when FEV1/FVC was less than 65%. Participants with both OAD and SAH had greater sleep perturbation and desaturation than those with one disorder. Generally mild OAD alone was associated with minimally altered sleep quality. We conclude that (1) there is no association between generally mild OAD and SAH; (2) exclusive of SAH and after adjusting for demographic factors and awake oxyhemoglobin saturation, an FEV1/FVC value less than 65% is associated with increased risk of sleep desaturation; (3) desaturation is greater in persons with both OAD and SAH compared with each of these alone; and (4) individuals with generally mild OAD and without SAH in the community have minimally perturbed sleep.
Tina V Hartert - One of the best experts on this subject based on the ideXlab platform.
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use of pulse oximetry to recognize severity of airflow obstruction in Obstructive Airway Disease correlation with pulsus paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
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Clinical Investigations in Critical CareUse of Pulse Oximetry to Recognize Severity of Airflow Obstruction in Obstructive Airway Disease: Correlation With Pulsus Paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
Eyal Shahar - One of the best experts on this subject based on the ideXlab platform.
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sleep and sleep disordered breathing in adults with predominantly mild Obstructive Airway Disease
American Journal of Respiratory and Critical Care Medicine, 2003Co-Authors: Mark H Sanders, Susan Redline, Anne B Newman, Michael D. Lebowitz, Catherine L Haggerty, Jonathan M Samet, George T Oconnor, Naresh M Punjabi, Eyal ShaharAbstract:Neither the association between Obstructive Airways Disease (OAD) and sleep apnea-hypopnea (SAH) nor the sleep consequences of each disorder alone and together have been characterized in an adult community setting. Our primary aims were (1) to determine if there is an association between OAD and SAH and (2) identify predictors of oxyhemoglobin desaturation during sleep in persons having OAD with and without SAH. Polysomnography and spirometry results from 5,954 participants in the Sleep Heart Health Study were analyzed. OAD was defined by a FEV1/FVC value less than 70%. Assessment of SAH prevalence in OAD was performed using thresholds of respiratory disturbance index (RDI) greater than 10 and greater than 15. A total of 1,132 participants had OAD that was predominantly mild (FEV1/FVC 63.81 +/- 6.56%, mean +/- SD). SAH was not more prevalent in participants with OAD than in those without OAD (22.32 versus 28.86%, with and without OAD, respectively, at RDI threshold values greater than 10; and 13.97 versus 18.63%, with and without OAD, respectively, at RDI threshold value greater than 15). In the absence of SAH, the adjusted odds ratio for sleep desaturation (> 5% total sleep time with saturation < 90%) was greater than 1.9 when FEV1/FVC was less than 65%. Participants with both OAD and SAH had greater sleep perturbation and desaturation than those with one disorder. Generally mild OAD alone was associated with minimally altered sleep quality. We conclude that (1) there is no association between generally mild OAD and SAH; (2) exclusive of SAH and after adjusting for demographic factors and awake oxyhemoglobin saturation, an FEV1/FVC value less than 65% is associated with increased risk of sleep desaturation; (3) desaturation is greater in persons with both OAD and SAH compared with each of these alone; and (4) individuals with generally mild OAD and without SAH in the community have minimally perturbed sleep.
Arthur P Wheeler - One of the best experts on this subject based on the ideXlab platform.
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use of pulse oximetry to recognize severity of airflow obstruction in Obstructive Airway Disease correlation with pulsus paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
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Clinical Investigations in Critical CareUse of Pulse Oximetry to Recognize Severity of Airflow Obstruction in Obstructive Airway Disease: Correlation With Pulsus Paradoxus
Chest, 1999Co-Authors: Tina V Hartert, Arthur P Wheeler, James R ShellerAbstract:Study objectives The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a measure of the severity of air trapping in Obstructive Airway Disease. Design Cross-sectional survey. Setting The ICU in a tertiary care academic hospital. Patients Twenty-six patients consecutively admitted to the ICU with Obstructive Airway Disease, either asthma or COPD. Measurements and results Forty-six percent of the study patients required mechanical ventilation, and 69% had an elevated pulsus paradoxus. We defined the altered pulse oximetry baseline tracing as the respiratory waveform variation (RWV). The RWV was measured in numerical form as the change in millimeters from the baseline. Pulsus paradoxus was significantly correlated with the RWV of the pulse oximetry tracing (p Conclusions We describe the characteristic alterations in the pulse oximetry tracings that occur in the presence of pulsus paradoxus and auto-PEEP. Since pulse oximetry is available universally in ICUs and emergency departments, it may be a useful noninvasive means of continually assessing pulsus paradoxus and air trapping severity in Obstructive Airway Disease patients.
