The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Thomas L Diepgen - One of the best experts on this subject based on the ideXlab platform.
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skin cancer induced by natural uv radiation as an Occupational Disease requirements for its notification and recognition
Journal Der Deutschen Dermatologischen Gesellschaft, 2014Co-Authors: Thomas L Diepgen, S Brandenburg, Werner Aberer, Andrea Bauer, Hans Drexler, M Fartasch, Swen Malte John, S Krohn, Stefanie Palfner, W RomerAbstract:Summary In Germany over 2.5 million employees have an increased risk of skin cancer due to their Occupational exposure to natural UV-irradiation. The medical consultation board “Occupational Diseases” of the Ministry of Labor and Social affairs has investigated the association between Occupational UV-irradiation and skin cancer risk and recommends to add the following new Occupational Disease into the appendix1 of the German ordinance on Occupational Diseases: “Squamous cell carcinoma and multiple actinic keratosis due to natural UV-irradiation”. In this article we report in the view of the German Society of Occupational and Environmental Dermatology (ABD) and the German Statutory accident insurance (DGUV), whose criteria have to be fulfilled for the notification and recognition of an Occupational skin cancer due to natural UV-irradiation.
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the relationship between Occupational sun exposure and non melanoma skin cancer clinical basics epidemiology Occupational Disease evaluation and prevention
Deutsches Arzteblatt International, 2012Co-Authors: M Fartasch, Thomas L Diepgen, Jochen Schmitt, Hans DrexlerAbstract:SUMMARY Background: The cumulative effect of solar ultraviolet (UV) radiation is responsible for the worldwide increase in non-melanoma skin cancer, a category that includes squamous cell carcinoma and its precursors (the actinic keratoses) as well as basal-cell carcinoma. Non-melanoma skin cancer is the most common type of cancer in areas of the world with a light-skinned population. The Occupational exposure to UV radiation is high in many outdoor occupations; recent studies suggest that persons working in such occupations are more likely to develop non-melanoma skin cancer. Methods: On the basis of a selective review of the literature, we present the current state of knowledge about Occupational and non-Occupational UV exposure and the findings of meta-analyses on the association of outdoor activity with non-melanoma skin cancer. We also give an overview of the current recommendations for prevention and for medicolegal assessment. Results: Recent meta-analyses have consistently documented a significantly higher risk of squamous cell carcinoma of the skin among persons who work outdoors (odds ratio [OR] 1.77, 95% confidence interval [CI] 1.40–2.22, p<0.001). There is also evidence for an elevated risk of basal-cell carcinoma (OR 1.43, 95% CI 1.23–1.66, p = 0.0001), but the effect is of lesser magnitude and the study findings are not as uniform. Conclusion: The association of Occupational exposure to solar UV radiation with squamous cell carcinoma, including actinic keratosis, has been conclusively demonstrated. It follows that, in Germany, suspected non-melanoma skin cancer in persons with high Occupational exposure to UV radiation should be reported as an Occupational Disease under § 9, paragraph 2 of the Seventh Book of the German Social Code (Sozialgesetzbuch, SGB VII). Preventive measures are urgently needed for persons with high Occupational exposure to UV radiation. ►Cite this as:
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Occupational exposure to non artificial uv light and non melanocytic skin cancer a systematic review concerning a new Occupational Disease
Journal Der Deutschen Dermatologischen Gesellschaft, 2009Co-Authors: Jochen Schmitt, Thomas L Diepgen, Andrea BauerAbstract:Summary Background: Although UV exposure is the most important risk factor for cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), a systematic review analyzing the risk of Occupational UV exposure is missing. Methods: Based on a systematic literature search in PubMed (until 05/2009) supplemented by hand search, the association between Occupational UV exposure and SCC and BCC was analyzed. Literature search and data abstraction was done independently by 2 reviewers. The association between Occupational UV exposure and cancer risk is presented as odds ratios (OR). Results: We identified 25 relevant epidemiologic studies (5 cohort studies, 17 case-control studies, 3 cross-sectional studies). 12 studies described a positive association between Occupational UV exposure and risk of SCC with OR > 3 in 6 studies and OR 1.5–2.0 in another 6 studies. 3 studies did not find a relevant association (OR: 1.0–1.4). A significant positive association between Occupational UV exposure and BCC was reported in 5 studies; 11 studies did not find a significant association. Conclusions: The association between Occupational UV exposure and SCC is well and consistently documented epidemiologically (approximately 2-fold increased risk), so that the criteria for a new Occupational Disease are fulfilled. The association with BCC is unclear due to significant methodological limitations in the published studies.
Hans Drexler - One of the best experts on this subject based on the ideXlab platform.
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skin cancer induced by natural uv radiation as an Occupational Disease requirements for its notification and recognition
Journal Der Deutschen Dermatologischen Gesellschaft, 2014Co-Authors: Thomas L Diepgen, S Brandenburg, Werner Aberer, Andrea Bauer, Hans Drexler, M Fartasch, Swen Malte John, S Krohn, Stefanie Palfner, W RomerAbstract:Summary In Germany over 2.5 million employees have an increased risk of skin cancer due to their Occupational exposure to natural UV-irradiation. The medical consultation board “Occupational Diseases” of the Ministry of Labor and Social affairs has investigated the association between Occupational UV-irradiation and skin cancer risk and recommends to add the following new Occupational Disease into the appendix1 of the German ordinance on Occupational Diseases: “Squamous cell carcinoma and multiple actinic keratosis due to natural UV-irradiation”. In this article we report in the view of the German Society of Occupational and Environmental Dermatology (ABD) and the German Statutory accident insurance (DGUV), whose criteria have to be fulfilled for the notification and recognition of an Occupational skin cancer due to natural UV-irradiation.
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the relationship between Occupational sun exposure and non melanoma skin cancer clinical basics epidemiology Occupational Disease evaluation and prevention
Deutsches Arzteblatt International, 2012Co-Authors: M Fartasch, Thomas L Diepgen, Jochen Schmitt, Hans DrexlerAbstract:SUMMARY Background: The cumulative effect of solar ultraviolet (UV) radiation is responsible for the worldwide increase in non-melanoma skin cancer, a category that includes squamous cell carcinoma and its precursors (the actinic keratoses) as well as basal-cell carcinoma. Non-melanoma skin cancer is the most common type of cancer in areas of the world with a light-skinned population. The Occupational exposure to UV radiation is high in many outdoor occupations; recent studies suggest that persons working in such occupations are more likely to develop non-melanoma skin cancer. Methods: On the basis of a selective review of the literature, we present the current state of knowledge about Occupational and non-Occupational UV exposure and the findings of meta-analyses on the association of outdoor activity with non-melanoma skin cancer. We also give an overview of the current recommendations for prevention and for medicolegal assessment. Results: Recent meta-analyses have consistently documented a significantly higher risk of squamous cell carcinoma of the skin among persons who work outdoors (odds ratio [OR] 1.77, 95% confidence interval [CI] 1.40–2.22, p<0.001). There is also evidence for an elevated risk of basal-cell carcinoma (OR 1.43, 95% CI 1.23–1.66, p = 0.0001), but the effect is of lesser magnitude and the study findings are not as uniform. Conclusion: The association of Occupational exposure to solar UV radiation with squamous cell carcinoma, including actinic keratosis, has been conclusively demonstrated. It follows that, in Germany, suspected non-melanoma skin cancer in persons with high Occupational exposure to UV radiation should be reported as an Occupational Disease under § 9, paragraph 2 of the Seventh Book of the German Social Code (Sozialgesetzbuch, SGB VII). Preventive measures are urgently needed for persons with high Occupational exposure to UV radiation. ►Cite this as:
Andrea Bauer - One of the best experts on this subject based on the ideXlab platform.
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skin cancer induced by natural uv radiation as an Occupational Disease requirements for its notification and recognition
Journal Der Deutschen Dermatologischen Gesellschaft, 2014Co-Authors: Thomas L Diepgen, S Brandenburg, Werner Aberer, Andrea Bauer, Hans Drexler, M Fartasch, Swen Malte John, S Krohn, Stefanie Palfner, W RomerAbstract:Summary In Germany over 2.5 million employees have an increased risk of skin cancer due to their Occupational exposure to natural UV-irradiation. The medical consultation board “Occupational Diseases” of the Ministry of Labor and Social affairs has investigated the association between Occupational UV-irradiation and skin cancer risk and recommends to add the following new Occupational Disease into the appendix1 of the German ordinance on Occupational Diseases: “Squamous cell carcinoma and multiple actinic keratosis due to natural UV-irradiation”. In this article we report in the view of the German Society of Occupational and Environmental Dermatology (ABD) and the German Statutory accident insurance (DGUV), whose criteria have to be fulfilled for the notification and recognition of an Occupational skin cancer due to natural UV-irradiation.
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Occupational exposure to non artificial uv light and non melanocytic skin cancer a systematic review concerning a new Occupational Disease
Journal Der Deutschen Dermatologischen Gesellschaft, 2009Co-Authors: Jochen Schmitt, Thomas L Diepgen, Andrea BauerAbstract:Summary Background: Although UV exposure is the most important risk factor for cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), a systematic review analyzing the risk of Occupational UV exposure is missing. Methods: Based on a systematic literature search in PubMed (until 05/2009) supplemented by hand search, the association between Occupational UV exposure and SCC and BCC was analyzed. Literature search and data abstraction was done independently by 2 reviewers. The association between Occupational UV exposure and cancer risk is presented as odds ratios (OR). Results: We identified 25 relevant epidemiologic studies (5 cohort studies, 17 case-control studies, 3 cross-sectional studies). 12 studies described a positive association between Occupational UV exposure and risk of SCC with OR > 3 in 6 studies and OR 1.5–2.0 in another 6 studies. 3 studies did not find a relevant association (OR: 1.0–1.4). A significant positive association between Occupational UV exposure and BCC was reported in 5 studies; 11 studies did not find a significant association. Conclusions: The association between Occupational UV exposure and SCC is well and consistently documented epidemiologically (approximately 2-fold increased risk), so that the criteria for a new Occupational Disease are fulfilled. The association with BCC is unclear due to significant methodological limitations in the published studies.
M Fartasch - One of the best experts on this subject based on the ideXlab platform.
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skin cancer induced by natural uv radiation as an Occupational Disease requirements for its notification and recognition
Journal Der Deutschen Dermatologischen Gesellschaft, 2014Co-Authors: Thomas L Diepgen, S Brandenburg, Werner Aberer, Andrea Bauer, Hans Drexler, M Fartasch, Swen Malte John, S Krohn, Stefanie Palfner, W RomerAbstract:Summary In Germany over 2.5 million employees have an increased risk of skin cancer due to their Occupational exposure to natural UV-irradiation. The medical consultation board “Occupational Diseases” of the Ministry of Labor and Social affairs has investigated the association between Occupational UV-irradiation and skin cancer risk and recommends to add the following new Occupational Disease into the appendix1 of the German ordinance on Occupational Diseases: “Squamous cell carcinoma and multiple actinic keratosis due to natural UV-irradiation”. In this article we report in the view of the German Society of Occupational and Environmental Dermatology (ABD) and the German Statutory accident insurance (DGUV), whose criteria have to be fulfilled for the notification and recognition of an Occupational skin cancer due to natural UV-irradiation.
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the relationship between Occupational sun exposure and non melanoma skin cancer clinical basics epidemiology Occupational Disease evaluation and prevention
Deutsches Arzteblatt International, 2012Co-Authors: M Fartasch, Thomas L Diepgen, Jochen Schmitt, Hans DrexlerAbstract:SUMMARY Background: The cumulative effect of solar ultraviolet (UV) radiation is responsible for the worldwide increase in non-melanoma skin cancer, a category that includes squamous cell carcinoma and its precursors (the actinic keratoses) as well as basal-cell carcinoma. Non-melanoma skin cancer is the most common type of cancer in areas of the world with a light-skinned population. The Occupational exposure to UV radiation is high in many outdoor occupations; recent studies suggest that persons working in such occupations are more likely to develop non-melanoma skin cancer. Methods: On the basis of a selective review of the literature, we present the current state of knowledge about Occupational and non-Occupational UV exposure and the findings of meta-analyses on the association of outdoor activity with non-melanoma skin cancer. We also give an overview of the current recommendations for prevention and for medicolegal assessment. Results: Recent meta-analyses have consistently documented a significantly higher risk of squamous cell carcinoma of the skin among persons who work outdoors (odds ratio [OR] 1.77, 95% confidence interval [CI] 1.40–2.22, p<0.001). There is also evidence for an elevated risk of basal-cell carcinoma (OR 1.43, 95% CI 1.23–1.66, p = 0.0001), but the effect is of lesser magnitude and the study findings are not as uniform. Conclusion: The association of Occupational exposure to solar UV radiation with squamous cell carcinoma, including actinic keratosis, has been conclusively demonstrated. It follows that, in Germany, suspected non-melanoma skin cancer in persons with high Occupational exposure to UV radiation should be reported as an Occupational Disease under § 9, paragraph 2 of the Seventh Book of the German Social Code (Sozialgesetzbuch, SGB VII). Preventive measures are urgently needed for persons with high Occupational exposure to UV radiation. ►Cite this as:
Swen Malte John - One of the best experts on this subject based on the ideXlab platform.
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consensus report recognizing non melanoma skin cancer including actinic keratosis as an Occupational Disease a call to action
Journal of The European Academy of Dermatology and Venereology, 2016Co-Authors: Swen Malte John, M Trakatelli, R Gehring, K Finlay, C Fionda, M Wittlich, M Augustin, G Hilpert, J Barroso M Dias, C UlrichAbstract:Non-melanoma skin cancer (NMSC) is by far the most common cancer diagnosed in westernized countries,[1-5] and one of the few almost preventable cancers if detected and treated early as up to 90% of NMSC may be attributed to excessive exposure to ultraviolet radiation.[6] The incidence of NMSC is increasing: 2–3 million people are diagnosed worldwide annually, with an average yearly increase of 3–8% among white populations in Australia, Europe, the US and Canada over the last 30 years.[2-5, 7] The link between solar ultraviolet (UV) radiation and certain forms of NMSC is clearly recognized.[8, 9] It is estimated that outdoor workers are exposed to an UV radiation dose 2–3 times higher than indoor workers,[8] and there is a growing body of research linking UV radiation exposure in outdoor workers to NMSC: Occupationally UV-exposed workers are at least at a 43% higher risk of basal cell carcinoma (BCC) and almost doubled risk of squamous cell carcinoma (SCC) compared to the average population, with risk increasing with decreasing latitude[10-12]. The risk for BCC, SCC and actinic keratosis (AK) among workers who have worked outdoors for more than 5 years is 3-fold higher than the risk among those with no years of working outdoors[12, 13]. Primary prevention, early detection, treatment and regular follow-up of skin cancer (NMSC and melanoma) are shown to be beneficial from a health economic perspective.[14-17] Action is needed at international, European and national level to legislate for recognizing AK and NMSC as an Occupational Disease, which has the potential to improve access to compensation and drive preventative activities. This report is a Call to Action for: The engagement of key stakeholders, including supranational institutions, national governments, trade organizations, employers, workers and patient organizations to drive change in prevention and protection of at-risk groups. Employers should be obliged to prevent outdoor worker's UV exposure from exceeding limit values, and to implement Occupational skin cancer screening programmes among the at-risk workforce. Educational programmes for the outdoor workforce are needed to improve health literacy and drive behavioural change. Nationally, steps to improve notifications and surveillance of skin cancers through both Occupational services and public health programmes are required. Future research activities should focus on the precise definition of at-risk groups among outdoor workers through increased data gathering, including UV-dosimetry, and evaluation.
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skin cancer induced by natural uv radiation as an Occupational Disease requirements for its notification and recognition
Journal Der Deutschen Dermatologischen Gesellschaft, 2014Co-Authors: Thomas L Diepgen, S Brandenburg, Werner Aberer, Andrea Bauer, Hans Drexler, M Fartasch, Swen Malte John, S Krohn, Stefanie Palfner, W RomerAbstract:Summary In Germany over 2.5 million employees have an increased risk of skin cancer due to their Occupational exposure to natural UV-irradiation. The medical consultation board “Occupational Diseases” of the Ministry of Labor and Social affairs has investigated the association between Occupational UV-irradiation and skin cancer risk and recommends to add the following new Occupational Disease into the appendix1 of the German ordinance on Occupational Diseases: “Squamous cell carcinoma and multiple actinic keratosis due to natural UV-irradiation”. In this article we report in the view of the German Society of Occupational and Environmental Dermatology (ABD) and the German Statutory accident insurance (DGUV), whose criteria have to be fulfilled for the notification and recognition of an Occupational skin cancer due to natural UV-irradiation.
