The Experts below are selected from a list of 55212 Experts worldwide ranked by ideXlab platform
Emmanuel Wiernik - One of the best experts on this subject based on the ideXlab platform.
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association between current perceived stress and incident diabetes is dependent on Occupational Status evidence from the ipc cohort study
Diabetes & Metabolism, 2016Co-Authors: Emmanuel Wiernik, Bruno Pannier, Hermann Nabi, O Hanon, Tabassome Simon, Frederique Thomas, Nicolas Danchin, J M Simon, Frederic LimosinAbstract:Abstract Aim The role of stress in the onset of type 2 diabetes is a widespread lay belief, yet observational studies have produced inconsistent results. This study aimed to test the hypothesis that the association between perceived stress and incident diabetes might depend on Occupational Status (OS). Methods The four-item Perceived Stress Scale (PSS-4) was completed at baseline by 22,567 participants in the labour force (16,193 men, 6374 women; mean age: 44.5±9.8 years) who had undergone two health checkups subsidized by the French national healthcare system. All subjects were free from diabetes at baseline, defined as a fasting blood glycaemia≥7mmol/L or the use of antidiabetic drugs. Results After a mean follow-up of 5.3±2.1 years, 527 participants (2.3%) had incident diabetes. After adjusting for sociodemographic, behavioural and biomedical risk factors as well as self-rated health, the association between baseline perceived stress and diabetes at follow-up was non-significant for the total study population. However, perceived stress was significantly associated with incident diabetes in participants of low OS [odds ratio (OR) for a five-point increment: 1.39; 95% confidence interval (CI): 1.02–1.90]. In contrast, there was a negative association between perceived stress and diabetes among those of high OS (OR: 0.60; 95% CI: 0.41–0.88) and no association within other Occupational categories. The interaction between perceived stress and OS was significant ( P Conclusion This study suggests that the association between perceived stress and diabetes onset is dependent on OS. Furthermore, this association does not appear to be explained by the classical risk factors for diabetes.
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perceived stress sex and Occupational Status interact to increase the risk of future high blood pressure the ipc cohort study
Journal of Hypertension, 2014Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Cyril Ducolombier, Nicolas DanchinAbstract:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or Occupational Status. The 4-item Perceived Stress Scale was filled at baseline by 19 766 normotensive adults (13 652 men, mean age ± SD: 46.8 ± 9.3 years), without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs. After a mean follow-up of 5.8 ± 2.1 years, 3774 participants (19.1%) had high BP, defined as having a SBP at least 140 mmHg or a DBP at least 90 mmHg, or using antihypertensive drugs. There was a significant interaction between baseline-perceived stress and sex (P = 0.02) in relation to high BP at follow-up. After adjustment for potential confounders, baseline perceived stress was associated with high BP at follow-up in women [odds ratio 1.20, 95% confidence interval 1.03-1.38, P = 0.016). In addition, the interaction between perceived stress and Occupational Status was significant among women (P = 0.02). Baseline-perceived stress was positively associated with high BP at follow-up among women of medium or low Occupational Status, with odds ratio suggesting a linear increase of the risk (P = 0.005). Perceived stress may be considered as a risk factor for hypertension in women of lower Occupational Status. Research addressing the relationships between stress and high BP should systematically look for possible interactions with sex and Occupational Status.
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Occupational Status moderates the association between current perceived stress and high blood pressure evidence from the ipc cohort study
Hypertension, 2013Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Kathy Bean, Silla M ConsoliAbstract:Although lay beliefs commonly relate high blood pressure (BP) to psychological stress exposure, research findings are conflicting. This study examined the association between current perceived stress and high BP, and explored the potential impact of Occupational Status on this association. Resting BP was measured in 122 816 adults (84 994 men), aged ≥30 years (mean age±standard deviation: 46.8±9.9 years), without history of cardiovascular and renal disease and not on either psychotropic or antihypertensive drugs. High BP was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg. Perceived stress in the past month was measured with the 4-item perceived stress scale. A total of 33 154 participants (27.0%) had high BP (151±14/90±9 mm Hg). After adjustment for all variables except Occupational Status, perceived stress was associated with high BP (odds ratio [OR] for a 5-point increase: 1.06; 95% confidence interval [CI]: 1.03-1.09). This association was no longer significant after additional adjustment for Occupational Status (OR: 1.01; 95% CI: 0.99-1.04). There was a significant interaction (P<0.001) between perceived stress and Occupational Status in relation to BP: perceived stress was negatively associated with high BP among individuals of high Occupational Status (OR: 0.91; 95% CI: 0.87-0.96), but positively associated among those of low Status (OR: 1.10; 95% CI: 1.03-1.17) or unemployed (OR: 1.13; 95% CI: 1.03-1.24). Sensitivity analyses yielded similar results. The association between current perceived stress and BP depends on Occupational Status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms.
Tabassome Simon - One of the best experts on this subject based on the ideXlab platform.
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association between current perceived stress and incident diabetes is dependent on Occupational Status evidence from the ipc cohort study
Diabetes & Metabolism, 2016Co-Authors: Emmanuel Wiernik, Bruno Pannier, Hermann Nabi, O Hanon, Tabassome Simon, Frederique Thomas, Nicolas Danchin, J M Simon, Frederic LimosinAbstract:Abstract Aim The role of stress in the onset of type 2 diabetes is a widespread lay belief, yet observational studies have produced inconsistent results. This study aimed to test the hypothesis that the association between perceived stress and incident diabetes might depend on Occupational Status (OS). Methods The four-item Perceived Stress Scale (PSS-4) was completed at baseline by 22,567 participants in the labour force (16,193 men, 6374 women; mean age: 44.5±9.8 years) who had undergone two health checkups subsidized by the French national healthcare system. All subjects were free from diabetes at baseline, defined as a fasting blood glycaemia≥7mmol/L or the use of antidiabetic drugs. Results After a mean follow-up of 5.3±2.1 years, 527 participants (2.3%) had incident diabetes. After adjusting for sociodemographic, behavioural and biomedical risk factors as well as self-rated health, the association between baseline perceived stress and diabetes at follow-up was non-significant for the total study population. However, perceived stress was significantly associated with incident diabetes in participants of low OS [odds ratio (OR) for a five-point increment: 1.39; 95% confidence interval (CI): 1.02–1.90]. In contrast, there was a negative association between perceived stress and diabetes among those of high OS (OR: 0.60; 95% CI: 0.41–0.88) and no association within other Occupational categories. The interaction between perceived stress and OS was significant ( P Conclusion This study suggests that the association between perceived stress and diabetes onset is dependent on OS. Furthermore, this association does not appear to be explained by the classical risk factors for diabetes.
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perceived stress sex and Occupational Status interact to increase the risk of future high blood pressure the ipc cohort study
Journal of Hypertension, 2014Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Cyril Ducolombier, Nicolas DanchinAbstract:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or Occupational Status. The 4-item Perceived Stress Scale was filled at baseline by 19 766 normotensive adults (13 652 men, mean age ± SD: 46.8 ± 9.3 years), without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs. After a mean follow-up of 5.8 ± 2.1 years, 3774 participants (19.1%) had high BP, defined as having a SBP at least 140 mmHg or a DBP at least 90 mmHg, or using antihypertensive drugs. There was a significant interaction between baseline-perceived stress and sex (P = 0.02) in relation to high BP at follow-up. After adjustment for potential confounders, baseline perceived stress was associated with high BP at follow-up in women [odds ratio 1.20, 95% confidence interval 1.03-1.38, P = 0.016). In addition, the interaction between perceived stress and Occupational Status was significant among women (P = 0.02). Baseline-perceived stress was positively associated with high BP at follow-up among women of medium or low Occupational Status, with odds ratio suggesting a linear increase of the risk (P = 0.005). Perceived stress may be considered as a risk factor for hypertension in women of lower Occupational Status. Research addressing the relationships between stress and high BP should systematically look for possible interactions with sex and Occupational Status.
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Occupational Status moderates the association between current perceived stress and high blood pressure evidence from the ipc cohort study
Hypertension, 2013Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Kathy Bean, Silla M ConsoliAbstract:Although lay beliefs commonly relate high blood pressure (BP) to psychological stress exposure, research findings are conflicting. This study examined the association between current perceived stress and high BP, and explored the potential impact of Occupational Status on this association. Resting BP was measured in 122 816 adults (84 994 men), aged ≥30 years (mean age±standard deviation: 46.8±9.9 years), without history of cardiovascular and renal disease and not on either psychotropic or antihypertensive drugs. High BP was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg. Perceived stress in the past month was measured with the 4-item perceived stress scale. A total of 33 154 participants (27.0%) had high BP (151±14/90±9 mm Hg). After adjustment for all variables except Occupational Status, perceived stress was associated with high BP (odds ratio [OR] for a 5-point increase: 1.06; 95% confidence interval [CI]: 1.03-1.09). This association was no longer significant after additional adjustment for Occupational Status (OR: 1.01; 95% CI: 0.99-1.04). There was a significant interaction (P<0.001) between perceived stress and Occupational Status in relation to BP: perceived stress was negatively associated with high BP among individuals of high Occupational Status (OR: 0.91; 95% CI: 0.87-0.96), but positively associated among those of low Status (OR: 1.10; 95% CI: 1.03-1.17) or unemployed (OR: 1.13; 95% CI: 1.03-1.24). Sensitivity analyses yielded similar results. The association between current perceived stress and BP depends on Occupational Status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms.
O Hanon - One of the best experts on this subject based on the ideXlab platform.
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association between current perceived stress and incident diabetes is dependent on Occupational Status evidence from the ipc cohort study
Diabetes & Metabolism, 2016Co-Authors: Emmanuel Wiernik, Bruno Pannier, Hermann Nabi, O Hanon, Tabassome Simon, Frederique Thomas, Nicolas Danchin, J M Simon, Frederic LimosinAbstract:Abstract Aim The role of stress in the onset of type 2 diabetes is a widespread lay belief, yet observational studies have produced inconsistent results. This study aimed to test the hypothesis that the association between perceived stress and incident diabetes might depend on Occupational Status (OS). Methods The four-item Perceived Stress Scale (PSS-4) was completed at baseline by 22,567 participants in the labour force (16,193 men, 6374 women; mean age: 44.5±9.8 years) who had undergone two health checkups subsidized by the French national healthcare system. All subjects were free from diabetes at baseline, defined as a fasting blood glycaemia≥7mmol/L or the use of antidiabetic drugs. Results After a mean follow-up of 5.3±2.1 years, 527 participants (2.3%) had incident diabetes. After adjusting for sociodemographic, behavioural and biomedical risk factors as well as self-rated health, the association between baseline perceived stress and diabetes at follow-up was non-significant for the total study population. However, perceived stress was significantly associated with incident diabetes in participants of low OS [odds ratio (OR) for a five-point increment: 1.39; 95% confidence interval (CI): 1.02–1.90]. In contrast, there was a negative association between perceived stress and diabetes among those of high OS (OR: 0.60; 95% CI: 0.41–0.88) and no association within other Occupational categories. The interaction between perceived stress and OS was significant ( P Conclusion This study suggests that the association between perceived stress and diabetes onset is dependent on OS. Furthermore, this association does not appear to be explained by the classical risk factors for diabetes.
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perceived stress sex and Occupational Status interact to increase the risk of future high blood pressure the ipc cohort study
Journal of Hypertension, 2014Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Cyril Ducolombier, Nicolas DanchinAbstract:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or Occupational Status. The 4-item Perceived Stress Scale was filled at baseline by 19 766 normotensive adults (13 652 men, mean age ± SD: 46.8 ± 9.3 years), without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs. After a mean follow-up of 5.8 ± 2.1 years, 3774 participants (19.1%) had high BP, defined as having a SBP at least 140 mmHg or a DBP at least 90 mmHg, or using antihypertensive drugs. There was a significant interaction between baseline-perceived stress and sex (P = 0.02) in relation to high BP at follow-up. After adjustment for potential confounders, baseline perceived stress was associated with high BP at follow-up in women [odds ratio 1.20, 95% confidence interval 1.03-1.38, P = 0.016). In addition, the interaction between perceived stress and Occupational Status was significant among women (P = 0.02). Baseline-perceived stress was positively associated with high BP at follow-up among women of medium or low Occupational Status, with odds ratio suggesting a linear increase of the risk (P = 0.005). Perceived stress may be considered as a risk factor for hypertension in women of lower Occupational Status. Research addressing the relationships between stress and high BP should systematically look for possible interactions with sex and Occupational Status.
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Occupational Status moderates the association between current perceived stress and high blood pressure evidence from the ipc cohort study
Hypertension, 2013Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Kathy Bean, Silla M ConsoliAbstract:Although lay beliefs commonly relate high blood pressure (BP) to psychological stress exposure, research findings are conflicting. This study examined the association between current perceived stress and high BP, and explored the potential impact of Occupational Status on this association. Resting BP was measured in 122 816 adults (84 994 men), aged ≥30 years (mean age±standard deviation: 46.8±9.9 years), without history of cardiovascular and renal disease and not on either psychotropic or antihypertensive drugs. High BP was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg. Perceived stress in the past month was measured with the 4-item perceived stress scale. A total of 33 154 participants (27.0%) had high BP (151±14/90±9 mm Hg). After adjustment for all variables except Occupational Status, perceived stress was associated with high BP (odds ratio [OR] for a 5-point increase: 1.06; 95% confidence interval [CI]: 1.03-1.09). This association was no longer significant after additional adjustment for Occupational Status (OR: 1.01; 95% CI: 0.99-1.04). There was a significant interaction (P<0.001) between perceived stress and Occupational Status in relation to BP: perceived stress was negatively associated with high BP among individuals of high Occupational Status (OR: 0.91; 95% CI: 0.87-0.96), but positively associated among those of low Status (OR: 1.10; 95% CI: 1.03-1.17) or unemployed (OR: 1.13; 95% CI: 1.03-1.24). Sensitivity analyses yielded similar results. The association between current perceived stress and BP depends on Occupational Status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms.
Hermann Nabi - One of the best experts on this subject based on the ideXlab platform.
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association between current perceived stress and incident diabetes is dependent on Occupational Status evidence from the ipc cohort study
Diabetes & Metabolism, 2016Co-Authors: Emmanuel Wiernik, Bruno Pannier, Hermann Nabi, O Hanon, Tabassome Simon, Frederique Thomas, Nicolas Danchin, J M Simon, Frederic LimosinAbstract:Abstract Aim The role of stress in the onset of type 2 diabetes is a widespread lay belief, yet observational studies have produced inconsistent results. This study aimed to test the hypothesis that the association between perceived stress and incident diabetes might depend on Occupational Status (OS). Methods The four-item Perceived Stress Scale (PSS-4) was completed at baseline by 22,567 participants in the labour force (16,193 men, 6374 women; mean age: 44.5±9.8 years) who had undergone two health checkups subsidized by the French national healthcare system. All subjects were free from diabetes at baseline, defined as a fasting blood glycaemia≥7mmol/L or the use of antidiabetic drugs. Results After a mean follow-up of 5.3±2.1 years, 527 participants (2.3%) had incident diabetes. After adjusting for sociodemographic, behavioural and biomedical risk factors as well as self-rated health, the association between baseline perceived stress and diabetes at follow-up was non-significant for the total study population. However, perceived stress was significantly associated with incident diabetes in participants of low OS [odds ratio (OR) for a five-point increment: 1.39; 95% confidence interval (CI): 1.02–1.90]. In contrast, there was a negative association between perceived stress and diabetes among those of high OS (OR: 0.60; 95% CI: 0.41–0.88) and no association within other Occupational categories. The interaction between perceived stress and OS was significant ( P Conclusion This study suggests that the association between perceived stress and diabetes onset is dependent on OS. Furthermore, this association does not appear to be explained by the classical risk factors for diabetes.
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perceived stress sex and Occupational Status interact to increase the risk of future high blood pressure the ipc cohort study
Journal of Hypertension, 2014Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Cyril Ducolombier, Nicolas DanchinAbstract:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or Occupational Status. The 4-item Perceived Stress Scale was filled at baseline by 19 766 normotensive adults (13 652 men, mean age ± SD: 46.8 ± 9.3 years), without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs. After a mean follow-up of 5.8 ± 2.1 years, 3774 participants (19.1%) had high BP, defined as having a SBP at least 140 mmHg or a DBP at least 90 mmHg, or using antihypertensive drugs. There was a significant interaction between baseline-perceived stress and sex (P = 0.02) in relation to high BP at follow-up. After adjustment for potential confounders, baseline perceived stress was associated with high BP at follow-up in women [odds ratio 1.20, 95% confidence interval 1.03-1.38, P = 0.016). In addition, the interaction between perceived stress and Occupational Status was significant among women (P = 0.02). Baseline-perceived stress was positively associated with high BP at follow-up among women of medium or low Occupational Status, with odds ratio suggesting a linear increase of the risk (P = 0.005). Perceived stress may be considered as a risk factor for hypertension in women of lower Occupational Status. Research addressing the relationships between stress and high BP should systematically look for possible interactions with sex and Occupational Status.
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Occupational Status moderates the association between current perceived stress and high blood pressure evidence from the ipc cohort study
Hypertension, 2013Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Kathy Bean, Silla M ConsoliAbstract:Although lay beliefs commonly relate high blood pressure (BP) to psychological stress exposure, research findings are conflicting. This study examined the association between current perceived stress and high BP, and explored the potential impact of Occupational Status on this association. Resting BP was measured in 122 816 adults (84 994 men), aged ≥30 years (mean age±standard deviation: 46.8±9.9 years), without history of cardiovascular and renal disease and not on either psychotropic or antihypertensive drugs. High BP was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg. Perceived stress in the past month was measured with the 4-item perceived stress scale. A total of 33 154 participants (27.0%) had high BP (151±14/90±9 mm Hg). After adjustment for all variables except Occupational Status, perceived stress was associated with high BP (odds ratio [OR] for a 5-point increase: 1.06; 95% confidence interval [CI]: 1.03-1.09). This association was no longer significant after additional adjustment for Occupational Status (OR: 1.01; 95% CI: 0.99-1.04). There was a significant interaction (P<0.001) between perceived stress and Occupational Status in relation to BP: perceived stress was negatively associated with high BP among individuals of high Occupational Status (OR: 0.91; 95% CI: 0.87-0.96), but positively associated among those of low Status (OR: 1.10; 95% CI: 1.03-1.17) or unemployed (OR: 1.13; 95% CI: 1.03-1.24). Sensitivity analyses yielded similar results. The association between current perceived stress and BP depends on Occupational Status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms.
Frederique Thomas - One of the best experts on this subject based on the ideXlab platform.
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association between current perceived stress and incident diabetes is dependent on Occupational Status evidence from the ipc cohort study
Diabetes & Metabolism, 2016Co-Authors: Emmanuel Wiernik, Bruno Pannier, Hermann Nabi, O Hanon, Tabassome Simon, Frederique Thomas, Nicolas Danchin, J M Simon, Frederic LimosinAbstract:Abstract Aim The role of stress in the onset of type 2 diabetes is a widespread lay belief, yet observational studies have produced inconsistent results. This study aimed to test the hypothesis that the association between perceived stress and incident diabetes might depend on Occupational Status (OS). Methods The four-item Perceived Stress Scale (PSS-4) was completed at baseline by 22,567 participants in the labour force (16,193 men, 6374 women; mean age: 44.5±9.8 years) who had undergone two health checkups subsidized by the French national healthcare system. All subjects were free from diabetes at baseline, defined as a fasting blood glycaemia≥7mmol/L or the use of antidiabetic drugs. Results After a mean follow-up of 5.3±2.1 years, 527 participants (2.3%) had incident diabetes. After adjusting for sociodemographic, behavioural and biomedical risk factors as well as self-rated health, the association between baseline perceived stress and diabetes at follow-up was non-significant for the total study population. However, perceived stress was significantly associated with incident diabetes in participants of low OS [odds ratio (OR) for a five-point increment: 1.39; 95% confidence interval (CI): 1.02–1.90]. In contrast, there was a negative association between perceived stress and diabetes among those of high OS (OR: 0.60; 95% CI: 0.41–0.88) and no association within other Occupational categories. The interaction between perceived stress and OS was significant ( P Conclusion This study suggests that the association between perceived stress and diabetes onset is dependent on OS. Furthermore, this association does not appear to be explained by the classical risk factors for diabetes.
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perceived stress sex and Occupational Status interact to increase the risk of future high blood pressure the ipc cohort study
Journal of Hypertension, 2014Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Cyril Ducolombier, Nicolas DanchinAbstract:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or Occupational Status. The 4-item Perceived Stress Scale was filled at baseline by 19 766 normotensive adults (13 652 men, mean age ± SD: 46.8 ± 9.3 years), without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs. After a mean follow-up of 5.8 ± 2.1 years, 3774 participants (19.1%) had high BP, defined as having a SBP at least 140 mmHg or a DBP at least 90 mmHg, or using antihypertensive drugs. There was a significant interaction between baseline-perceived stress and sex (P = 0.02) in relation to high BP at follow-up. After adjustment for potential confounders, baseline perceived stress was associated with high BP at follow-up in women [odds ratio 1.20, 95% confidence interval 1.03-1.38, P = 0.016). In addition, the interaction between perceived stress and Occupational Status was significant among women (P = 0.02). Baseline-perceived stress was positively associated with high BP at follow-up among women of medium or low Occupational Status, with odds ratio suggesting a linear increase of the risk (P = 0.005). Perceived stress may be considered as a risk factor for hypertension in women of lower Occupational Status. Research addressing the relationships between stress and high BP should systematically look for possible interactions with sex and Occupational Status.
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Occupational Status moderates the association between current perceived stress and high blood pressure evidence from the ipc cohort study
Hypertension, 2013Co-Authors: Emmanuel Wiernik, Bruno Pannier, Sebastien Czernichow, Hermann Nabi, O Hanon, Tabassome Simon, Jeanmarc Simon, Frederique Thomas, Kathy Bean, Silla M ConsoliAbstract:Although lay beliefs commonly relate high blood pressure (BP) to psychological stress exposure, research findings are conflicting. This study examined the association between current perceived stress and high BP, and explored the potential impact of Occupational Status on this association. Resting BP was measured in 122 816 adults (84 994 men), aged ≥30 years (mean age±standard deviation: 46.8±9.9 years), without history of cardiovascular and renal disease and not on either psychotropic or antihypertensive drugs. High BP was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg. Perceived stress in the past month was measured with the 4-item perceived stress scale. A total of 33 154 participants (27.0%) had high BP (151±14/90±9 mm Hg). After adjustment for all variables except Occupational Status, perceived stress was associated with high BP (odds ratio [OR] for a 5-point increase: 1.06; 95% confidence interval [CI]: 1.03-1.09). This association was no longer significant after additional adjustment for Occupational Status (OR: 1.01; 95% CI: 0.99-1.04). There was a significant interaction (P<0.001) between perceived stress and Occupational Status in relation to BP: perceived stress was negatively associated with high BP among individuals of high Occupational Status (OR: 0.91; 95% CI: 0.87-0.96), but positively associated among those of low Status (OR: 1.10; 95% CI: 1.03-1.17) or unemployed (OR: 1.13; 95% CI: 1.03-1.24). Sensitivity analyses yielded similar results. The association between current perceived stress and BP depends on Occupational Status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms.
