The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform
Kiyoshi Hoshino - One of the best experts on this subject based on the ideXlab platform.
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A Compact Wearable Eye Movement Measurement System for Support of Safe Driving
2019 IEEE International Conference on Mechatronics (ICM), 2019Co-Authors: Kiyoshi HoshinoAbstract:If the eye movement of a driver who makes a long drive during the day and at night can be measured with less stress to the driver in order to estimate the following items for a long time with high accuracy, it is expected that the information will make a great contribution to safe driving: 1) What the driver is looking at or paying attention to (i.e. gaze), 2) A feeling or sign of unwellness such as dizziness, car sickness, and discomfort (i.e. rotational eye movement). In this study, the authors propose an approach in which an area of high intensity gradients in the white part of the eye, i.e. an area that includes a Blood Vessel with a distinctive shape, is automatically selected to estimate the gaze and calculate the angle of eye rotation, so that the target Ocular Blood Vessel can be tracked with high accuracy even if Blood Vessels in the white part of the eye differ considerably between individuals in terms of shape, length, and thickness. An evaluation experiment yielded excellent results under various lighting conditions. Especially, extremely positive results were obtained for the estimation accuracy of rotational eye movement, with an estimation error of -0.69° ± 1.02° (mean and standard deviation).
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ICM - A Compact Wearable Eye Movement Measurement System for Support of Safe Driving
2019 IEEE International Conference on Mechatronics (ICM), 2019Co-Authors: Kiyoshi HoshinoAbstract:If the eye movement of a driver who makes a long drive during the day and at night can be measured with less stress to the driver in order to estimate the following items for a long time with high accuracy, it is expected that the information will make a great contribution to safe driving: 1) What the driver is looking at or paying attention to (i.e. gaze), 2) A feeling or sign of unwellness such as dizziness, car sickness, and discomfort (i.e. rotational eye movement). In this study, the authors propose an approach in which an area of high intensity gradients in the white part of the eye, i.e. an area that includes a Blood Vessel with a distinctive shape, is automatically selected to estimate the gaze and calculate the angle of eye rotation, so that the target Ocular Blood Vessel can be tracked with high accuracy even if Blood Vessels in the white part of the eye differ considerably between individuals in terms of shape, length, and thickness. An evaluation experiment yielded excellent results under various lighting conditions. Especially, extremely positive results were obtained for the estimation accuracy of rotational eye movement, with an estimation error of −0.69° ± 1.02° (mean and standard deviation).
Mary E Dickinson - One of the best experts on this subject based on the ideXlab platform.
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the flk1 myr mcherry mouse as a useful reporter to characterize multiple aspects of Ocular Blood Vessel development and disease
Developmental Dynamics, 2009Co-Authors: Ross A Poche, Irina V Larina, Melissa L Scott, Jennifer E Saik, Jennifer L West, Mary E DickinsonAbstract:The highly vascularized mouse eye is an excellent model system in which to elucidate the molecular genetic basis of Blood Vessel development and disease. However, the analysis of Ocular Vessel defects has traditionally been derived from fixed tissue, which fails to account for dynamic events such as Blood flow and cell migration. To overcome the limitations of static analysis, tremendous advances in imaging technology and fluorescent protein reporter mouse lines now enable the direct visualization of developing cells in vivo. Here, we demonstrate that the Flk1-myr::mCherry transgenic mouse is an extremely useful live reporter with broad applicability to retinal, hyaloid, and choroid vascular research. Developmental Dynamics 238:2318–2326, 2009. © 2009 Wiley-Liss, Inc.
Ross A Poche - One of the best experts on this subject based on the ideXlab platform.
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the flk1 myr mcherry mouse as a useful reporter to characterize multiple aspects of Ocular Blood Vessel development and disease
Developmental Dynamics, 2009Co-Authors: Ross A Poche, Irina V Larina, Melissa L Scott, Jennifer E Saik, Jennifer L West, Mary E DickinsonAbstract:The highly vascularized mouse eye is an excellent model system in which to elucidate the molecular genetic basis of Blood Vessel development and disease. However, the analysis of Ocular Vessel defects has traditionally been derived from fixed tissue, which fails to account for dynamic events such as Blood flow and cell migration. To overcome the limitations of static analysis, tremendous advances in imaging technology and fluorescent protein reporter mouse lines now enable the direct visualization of developing cells in vivo. Here, we demonstrate that the Flk1-myr::mCherry transgenic mouse is an extremely useful live reporter with broad applicability to retinal, hyaloid, and choroid vascular research. Developmental Dynamics 238:2318–2326, 2009. © 2009 Wiley-Liss, Inc.
Peter G Smith - One of the best experts on this subject based on the ideXlab platform.
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increased Ocular Blood Vessel numbers and sizes following chronic sympathectomy in rat
Experimental Eye Research, 2002Co-Authors: Jena J Steinle, Janet D Pierce, Richard L Clancy, Peter G SmithAbstract:Disease states characterized by Ocular vascular pathology are often associated with impaired sympathetic function. This study examined the effect of sympathetic denervation on Ocular vasculature of the adult rat. Uveal perfusion and choroidal and retinal Blood Vessel sizes and numbers were assessed in rats with intact innervation and after short- (2 days) or long-term (6 weeks) sympathetic denervation induced by ipsilateral superior cervical ganglion excision. In rats with intact innervation and after short-term sympathectomy, Blood flow in both eyes was comparable. However, after long-term sympathectomy, Blood flow was four-fold greater in the denervated than in the innervated eye, but was unaltered in lacrimal gland, cerebral cortex, and masseter muscle. Choroid surface area was not affected by long-term sympathectomy, but choroidal thickness was increased and choroidal cross-sectional area occupied by vascular lumina was greater. Arteriolar number per unit cross-sectional area of choroid was not altered although arteriolar diameters were enlarged. Choroidal venules were larger and more abundant. Choroidal capillary numbers were unchanged, but retinal capillaries of the outer plexiform layer were increased. To determine if these changes result from loss of sympathetic activity, sympathetic preganglionic innervation was excised chronically. This produced significant increases in choroidal thickness and vascular luminal area, and in numbers of arterioles, small venules, and capillaries in the outer plexiform layer. These findings show that sympathetic innervation is critical in regulating choroidal and retinal vascularity, and that chronic loss of sympathetic activity may contribute to abnormal vascular proliferation in diseases such as age-related macular degeneration and diabetic retinopathy.
Irina V Larina - One of the best experts on this subject based on the ideXlab platform.
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the flk1 myr mcherry mouse as a useful reporter to characterize multiple aspects of Ocular Blood Vessel development and disease
Developmental Dynamics, 2009Co-Authors: Ross A Poche, Irina V Larina, Melissa L Scott, Jennifer E Saik, Jennifer L West, Mary E DickinsonAbstract:The highly vascularized mouse eye is an excellent model system in which to elucidate the molecular genetic basis of Blood Vessel development and disease. However, the analysis of Ocular Vessel defects has traditionally been derived from fixed tissue, which fails to account for dynamic events such as Blood flow and cell migration. To overcome the limitations of static analysis, tremendous advances in imaging technology and fluorescent protein reporter mouse lines now enable the direct visualization of developing cells in vivo. Here, we demonstrate that the Flk1-myr::mCherry transgenic mouse is an extremely useful live reporter with broad applicability to retinal, hyaloid, and choroid vascular research. Developmental Dynamics 238:2318–2326, 2009. © 2009 Wiley-Liss, Inc.
