The Experts below are selected from a list of 42 Experts worldwide ranked by ideXlab platform
Takashi Muraki - One of the best experts on this subject based on the ideXlab platform.
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reflux associated cholecystopathy analysis of 76 gallbladders from patients with supra Oddi union of the pancreatic duct and common bile duct pancreatobiliary maljunction elucidates a specific diagnostic pattern of mucosal hyperplasia as a prelude to
The American Journal of Surgical Pathology, 2017Co-Authors: Takashi Muraki, Bahar Memis, Michelle D Reid, Takeshi Uehara, Osamu Hasebe, Shinji Okaniwa, Naoto Horigome, Takeshi Hisa, Pardeep Kumar MittalAbstract:Pancreaticobiliary maljunction (PBM) is the anomalous union of the main pancreatic duct and common bile duct outside the Oddi-Sphincter, allowing the reflux of pancreatic juice to the gallbladder. There is only limited awareness and understanding of the pathologic correlates of this condition, mostl
Pardeep Kumar Mittal - One of the best experts on this subject based on the ideXlab platform.
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reflux associated cholecystopathy analysis of 76 gallbladders from patients with supra Oddi union of the pancreatic duct and common bile duct pancreatobiliary maljunction elucidates a specific diagnostic pattern of mucosal hyperplasia as a prelude to
The American Journal of Surgical Pathology, 2017Co-Authors: Takashi Muraki, Bahar Memis, Michelle D Reid, Takeshi Uehara, Osamu Hasebe, Shinji Okaniwa, Naoto Horigome, Takeshi Hisa, Pardeep Kumar MittalAbstract:Pancreaticobiliary maljunction (PBM) is the anomalous union of the main pancreatic duct and common bile duct outside the Oddi-Sphincter, allowing the reflux of pancreatic juice to the gallbladder. There is only limited awareness and understanding of the pathologic correlates of this condition, mostl
Keil Radan - One of the best experts on this subject based on the ideXlab platform.
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The use of physiological and pathophysiological pressure ratios in the area of the biliary ductal system and pancreas for diagnosis and treatment by endoscopic retrograde cholangiopancreatography
2009Co-Authors: Keil RadanAbstract::.In our work we wanted to confirm our clinical experience with therapy of biliary and pancreatic duct injuries from the endoscopic retrograde cholangiopancreatography (ERCP) which was done in 267. Children and infants with a variety of biliary tract disorders and traumatic injuries in the area of biliary and pancreatic duct.. Pressure of the bile plays the key role in the therapy of biliary tract injuries Therefore we have measured the pressure in biliary tract and duodenum before and after the Sphincterotomy of Oddi Sphincter. Thea aim of our study was to confirm the insertion of drainage into the biliary and pancreatic duct in children with injury in this area. Our results showed significant differences between biliary duct pressure and duodenal pressure in the patients before and after Sphincterotomy of Oddi Sphincter. This results on theoretical basis confirmed, that it is necessary in children after traumatic rupture of biliary duct to provide ERCP and insert a biliary drainage after Sphincterotomy. With this procedure the biliary tract injury is healed ad integrum without surgical liver resection. To provide only papiloSphincterotomy without biliary drainage is not sufficient. This new miniinvasive procedure plays a fundamental role in the therapy of blunt abdominal injuries in a children and infants..
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The use of physiological and pathophysiological pressure ratios in the area of the biliary ductal system and pancreas for diagnosis and treatment by endoscopic retrograde cholangiopancreatography
Univerzita Karlova 2. lékařská fakulta, 2009Co-Authors: Keil RadanAbstract:V naší práci jsme chtěli potvrdit naše klinické zkušenosti z endoskopické retrográdní cholangiopankreatografie /ERCP/, kterou jsme provedli u 267 dětí a kojenců s různým vrozeným či traumatickým postižením žlučových a pankreatických cest. Vzhledem k tomu, že intraduktální tlak ve žlučovém stromu hraje klíčovou roli v terapii poranění žlučových cest, zaměřili jsme se na endoskopické měření tlaku v oblasti žlučových cest a duodena. Naším cílem bylo potvrdit nutnost zavedení drenáže do oblasti žlučových cest a pankreatu u dětí s traumatickou rupturou těchto orgánů. Naše měření prokázala statisticky významný rozdíl tlaku ve žlučových cestách a duodenu u pacientů před a po provedené endoskopické papilosfinkterotomii Tato měření potvrdila nutnost provedení ERCP u dětí s traumatickou rupturou žlučových cest a nutnost zavedení drenáže po provedené sfinkterotomii. Tímto postupem se traumatická ruptura zhojí ad integrum bez nutnosti resekce jater. Pouhé provedení papilofinkterotomie bez zavedení biliární drenáže není dostatečné. Tento fakt má zásadní význam pro léčbu těchto poranění zvláště v dětském věku, kde je frekvence těchto poranění výrazně vyšší než ve věku dospělém.Velká část pacientů díky nově zavedeným postupům je léčena rychleji s menším množstvím komplikací, u části pacientů se díky těmto postupům...:.In our work we wanted to confirm our clinical experience with therapy of biliary and pancreatic duct injuries from the endoscopic retrograde cholangiopancreatography (ERCP) which was done in 267. Children and infants with a variety of biliary tract disorders and traumatic injuries in the area of biliary and pancreatic duct.. Pressure of the bile plays the key role in the therapy of biliary tract injuries Therefore we have measured the pressure in biliary tract and duodenum before and after the Sphincterotomy of Oddi Sphincter. Thea aim of our study was to confirm the insertion of drainage into the biliary and pancreatic duct in children with injury in this area. Our results showed significant differences between biliary duct pressure and duodenal pressure in the patients before and after Sphincterotomy of Oddi Sphincter. This results on theoretical basis confirmed, that it is necessary in children after traumatic rupture of biliary duct to provide ERCP and insert a biliary drainage after Sphincterotomy. With this procedure the biliary tract injury is healed ad integrum without surgical liver resection. To provide only papiloSphincterotomy without biliary drainage is not sufficient. This new miniinvasive procedure plays a fundamental role in the therapy of blunt abdominal injuries in a children and infants...Interní klinikaDepartment of Internal Medicine2. lékařská fakultaSecond Faculty of Medicin
Evan L Fogel - One of the best experts on this subject based on the ideXlab platform.
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frequency of Sphincter of Oddi dysfunction in patients with previously normal Sphincter of Oddi manometry studies
Endoscopy, 2009Co-Authors: Mouen A Khashab, James L Watkins, Lee Mchenry, Laura Lazzellpannell, Suzette Schmidt, Stuart Sherman, Glen A Lehman, Evan L FogelAbstract:BACKGROUND AND STUDY AIMS: Sphincter of Oddi manometry (SOM), performed at endoscopic retrograde cholangiopancreatography (ERCP), is the gold standard for diagnosing Sphincter of Oddi dysfunction (SOD). The question remains as to whether the short-term manometric recordings reflect the 24-hour pathophysiology of the Sphincter. The aim of this study was to determine the frequency of SOD in persistently symptomatic patients with previously normal SOM studies. PATIENTS AND METHODS: All patients who underwent ERCP for suspected SOD over a 13-year period (1994 - 2007) were considered for inclusion in the study. Patients with an intact papilla and a previously normal SOM who had a repeat ERCP for persistent symptoms formed the study group. SOM was performed in conventional retrograde fashion. RESULTS: In all, 5352 patients without prior papillary intervention underwent SOM during the study period. A total of 1037 patients had normal SOM, and of these, 30 patients (27 female, mean age 40.1 years) underwent repeat ERCP for persistent symptoms. The median duration between the two ERCPs was 493.5 days (range 52 - 3538 days). In these 30 patients, SOD classification prior to the initial ERCP was: type I in one patient (not treated in 1994), type II in 17 patients, and type III in 12 patients. Of the 30 patients, 12 (40 %) had normal SOM at repeat ERCP; SOD was diagnosed in 18/30 (60 %) patients. CONCLUSIONS: A single SOM study may not represent the day-to-day physiology of the Sphincter of Oddi; Sphincter pathology may progress over time. One normal exam may not rule out SOD. A repeat ERCP with manometry may be warranted in a subset of patients with persistent debilitating symptoms and a high index of suspicion for SOD. Outcome data are needed to determine whether this approach justifies the potential risks of ERCP.
Shinji Okaniwa - One of the best experts on this subject based on the ideXlab platform.
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reflux associated cholecystopathy analysis of 76 gallbladders from patients with supra Oddi union of the pancreatic duct and common bile duct pancreatobiliary maljunction elucidates a specific diagnostic pattern of mucosal hyperplasia as a prelude to
The American Journal of Surgical Pathology, 2017Co-Authors: Takashi Muraki, Bahar Memis, Michelle D Reid, Takeshi Uehara, Osamu Hasebe, Shinji Okaniwa, Naoto Horigome, Takeshi Hisa, Pardeep Kumar MittalAbstract:Pancreaticobiliary maljunction (PBM) is the anomalous union of the main pancreatic duct and common bile duct outside the Oddi-Sphincter, allowing the reflux of pancreatic juice to the gallbladder. There is only limited awareness and understanding of the pathologic correlates of this condition, mostl
