Olpadronic Acid

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Lidia P. Loginova - One of the best experts on this subject based on the ideXlab platform.

  • Re-evaluated data of dissociation constants of alendronic, pamidronic and Olpadronic Acids
    Central European Journal of Chemistry, 2009
    Co-Authors: Alexander P. Boichenko, Vadim V. Markov, Hoan Kong, Anna G. Matveeva, Lidia P. Loginova
    Abstract:

    The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) Acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (Olpadronic) Acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) Acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic Acid, the dissociation constants of alendronic, Olpadronic and pamidronic Acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by Acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic Acid dissociation constants.

Alexander P. Boichenko - One of the best experts on this subject based on the ideXlab platform.

  • Re-evaluated data of dissociation constants of alendronic, pamidronic and Olpadronic Acids
    Central European Journal of Chemistry, 2009
    Co-Authors: Alexander P. Boichenko, Vadim V. Markov, Hoan Kong, Anna G. Matveeva, Lidia P. Loginova
    Abstract:

    The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) Acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (Olpadronic) Acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) Acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic Acid, the dissociation constants of alendronic, Olpadronic and pamidronic Acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by Acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic Acid dissociation constants.

Vadim V. Markov - One of the best experts on this subject based on the ideXlab platform.

  • Re-evaluated data of dissociation constants of alendronic, pamidronic and Olpadronic Acids
    Central European Journal of Chemistry, 2009
    Co-Authors: Alexander P. Boichenko, Vadim V. Markov, Hoan Kong, Anna G. Matveeva, Lidia P. Loginova
    Abstract:

    The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) Acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (Olpadronic) Acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) Acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic Acid, the dissociation constants of alendronic, Olpadronic and pamidronic Acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by Acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic Acid dissociation constants.

Hoan Kong - One of the best experts on this subject based on the ideXlab platform.

  • Re-evaluated data of dissociation constants of alendronic, pamidronic and Olpadronic Acids
    Central European Journal of Chemistry, 2009
    Co-Authors: Alexander P. Boichenko, Vadim V. Markov, Hoan Kong, Anna G. Matveeva, Lidia P. Loginova
    Abstract:

    The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) Acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (Olpadronic) Acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) Acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic Acid, the dissociation constants of alendronic, Olpadronic and pamidronic Acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by Acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic Acid dissociation constants.

Anna G. Matveeva - One of the best experts on this subject based on the ideXlab platform.

  • Re-evaluated data of dissociation constants of alendronic, pamidronic and Olpadronic Acids
    Central European Journal of Chemistry, 2009
    Co-Authors: Alexander P. Boichenko, Vadim V. Markov, Hoan Kong, Anna G. Matveeva, Lidia P. Loginova
    Abstract:

    The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) Acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (Olpadronic) Acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) Acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic Acid, the dissociation constants of alendronic, Olpadronic and pamidronic Acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by Acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic Acid dissociation constants.