The Experts below are selected from a list of 186 Experts worldwide ranked by ideXlab platform
Domenica Lorusso - One of the best experts on this subject based on the ideXlab platform.
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advanced ovarian cancer Omental Bursa lesser omentum celiac portal and triad nodes spread as cause of inaccurate evaluation of residual tumor
Gynecologic Oncology, 2013Co-Authors: Francesco Raspagliesi, Antonino Ditto, Fabio Martinelli, Edward Haeusler, Domenica LorussoAbstract:Abstract Objective We evaluated the role of Omental Bursa (OB), surface of the pancreas, lesser omentum, caudate lobe, celiac nodes (CNs), portal nodes and triad nodes spread in advanced ovarian cancer (AOC). We investigated if the exploration and cleaning up of these areas can lead to a more complete cytoreduction and to a more realistic assessment of residual tumor in AOC. Methods We prospectively recruited patients diagnosed with AOC, who underwent a complete cytoreduction. Demographics, surgical procedures, morbidities, pathologic findings and correlations with OB spread were assessed. Results A total of 37 patients had an optimal debulking including OB evaluation and peritonectomy. The OB area procedure required in mean 65min with an estimated blood loss of 250ml. OB involvement was found in 67% (25/37) of cases. Peritoneal disease was found in 22 cases including 18 supragastric lesser sac and 4 porta hepatis peritoneum. CNs metastases were found in 5 cases, of which 3 cases are with bulky nodes, all presented also bulky nodes in the para-aortic area. Only in the case of a macroscopic involvement of the diaphragm OB was positive for disease. When adhesions occluding the Winslow foramen were present, no OB peritoneum involvement was found. OB resection related complications were low (2 out 25). Conclusions The data of this prospective study demonstrate the high rate of OB, surface of the pancreas, lesser omentum, caudate lobe, CNs, portal and triad nodes involvement and the value of investigating the dissemination and cytoreduction in these sites to obtain a real optimal debulking.
Shusen Zheng - One of the best experts on this subject based on the ideXlab platform.
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carcinosarcoma of the lesser omentum a unique case report and literature review
Medicine, 2016Co-Authors: Bei Wang, Kuiwu Ren, Yunchuan Yang, Dalong Wan, Zhenglong Zhai, Lele Zhang, Shusen ZhengAbstract:Carcinosarcoma is a rare tumor consisting of epithelial and mesenchymal components, both of which are histologically malignant. It usually runs an aggressive clinical course, with higher metastatic potential than other kinds of carcinomas or sarcomas.Here, we present an extremely uncommon case of carcinosarcoma occurred in the lesser Omental Bursa in a 65-year-old Chinese man. Metastasis was observed 2 months after operation and disappeared completely after chemotherapy. Until now, 3 years after surgery, the patient is still alive without any signs or symptoms of recurrence.To our knowledge, this is the first case of carcinosarcoma originated from lesser omentum. Surgical resection and the ifosfamide-based combination chemotherapy may be effective to carcinosarcoma in the lesser omentum.
Nikoloz Tsikolia - One of the best experts on this subject based on the ideXlab platform.
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initial morphological symmetry breaking in the foregut and development of the Omental Bursa in human embryos
Journal of Anatomy, 2021Co-Authors: Tobias Schafer, Viktoria Stankova, Christoph Viebahn, Bernadette S De Bakker, Nikoloz TsikoliaAbstract:Bilaterally symmetrical primordia of visceral organs undergo asymmetrical morphogenesis leading to typical arrangement of visceral organs in the adult. Asymmetrical morphogenesis within the upper abdomen leads, among others, to the formation of the Omental Bursa dorsally to the rotated stomach. A widespread view of this process assumes kinking of thin mesenteries as a main mechanism. This view is based on a theory proposed already by Johannes Muller in 1830 and was repeatedly criticized, but some of the most plausible alternative views (initially proposed by Swaen in 1897 and Broman in 1904) still remain to be proven. Here, we analyzed serial histological sections of human embryos between stages 12 and 15 at high light microscopical resolution to reveal the succession of events giving rise to the development of the Omental Bursa and its relation to the emerging stomach asymmetry. Our analysis indicates that morphological symmetry breaking in the upper abdomen occurs within a wide mesenchymal plate called here mesenteric septum and is based on differential behavior of the coelomic epithelium which causes asymmetric paragastric recess formation and, importantly, precedes initial rotation of stomach. Our results thus provide the first histological evidence of breaking the symmetry of the early foregut anlage in the human embryo and pave the way for experimental studies of left-right symmetry breaking in the upper abdomen in experimental model organisms.
Francesco Raspagliesi - One of the best experts on this subject based on the ideXlab platform.
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advanced ovarian cancer Omental Bursa lesser omentum celiac portal and triad nodes spread as cause of inaccurate evaluation of residual tumor
Gynecologic Oncology, 2013Co-Authors: Francesco Raspagliesi, Antonino Ditto, Fabio Martinelli, Edward Haeusler, Domenica LorussoAbstract:Abstract Objective We evaluated the role of Omental Bursa (OB), surface of the pancreas, lesser omentum, caudate lobe, celiac nodes (CNs), portal nodes and triad nodes spread in advanced ovarian cancer (AOC). We investigated if the exploration and cleaning up of these areas can lead to a more complete cytoreduction and to a more realistic assessment of residual tumor in AOC. Methods We prospectively recruited patients diagnosed with AOC, who underwent a complete cytoreduction. Demographics, surgical procedures, morbidities, pathologic findings and correlations with OB spread were assessed. Results A total of 37 patients had an optimal debulking including OB evaluation and peritonectomy. The OB area procedure required in mean 65min with an estimated blood loss of 250ml. OB involvement was found in 67% (25/37) of cases. Peritoneal disease was found in 22 cases including 18 supragastric lesser sac and 4 porta hepatis peritoneum. CNs metastases were found in 5 cases, of which 3 cases are with bulky nodes, all presented also bulky nodes in the para-aortic area. Only in the case of a macroscopic involvement of the diaphragm OB was positive for disease. When adhesions occluding the Winslow foramen were present, no OB peritoneum involvement was found. OB resection related complications were low (2 out 25). Conclusions The data of this prospective study demonstrate the high rate of OB, surface of the pancreas, lesser omentum, caudate lobe, CNs, portal and triad nodes involvement and the value of investigating the dissemination and cytoreduction in these sites to obtain a real optimal debulking.
Morito Monden - One of the best experts on this subject based on the ideXlab platform.
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a new technique for laparoscopic resection of a submucosal tumor on the posterior wall of the gastric fundus
Surgical Endoscopy and Other Interventional Techniques, 1999Co-Authors: Mitsugu Sekimoto, Shigeyuki Tamura, Yasunori Hasuike, Masahiko Yano, Atsuo Murata, Masatoshi Inoue, Hitoshi Shiozaki, Morito MondenAbstract:Several reports have been published which describe the technique of using an Endo GIA to resect submucosal tumors on the anterior wall of the stomach. Lesions on the posterior wall, however, especially near the esophagocardiac junction (ECJ), are difficult to resect using these reported techniques. This is because the surgeon must divide the omentum and enter the Omental Bursa in order to use a similar extraluminal technique. Furthermore, special care must be taken to ensure that resections do not involve the ECJ and narrow the esophagus. In order to overcome these difficulties, we have proposed a new technique for the laparoscopic excision of a submucosal tumor located on the posterior wall of the gastric fundus. The principle of this procedure involves the intraluminal resection of the submucosal tumor, including the surrounding stomach wall, using the Endo GIA. This technique is safe, simple, and effective. We believe that we are the first to address the excision of a submucosal lesion by resecting the full thickness of the posterior gastric wall lesion intraluminally.
