The Experts below are selected from a list of 3798 Experts worldwide ranked by ideXlab platform
Renato Fanchin - One of the best experts on this subject based on the ideXlab platform.
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ureteral injury after transvaginal ultrasound guided Oocyte Retrieval a complication of in vitro fertilization embryo transfer that may lurk undetected in women presenting with severe ovarian hyperstimulation syndrome
Fertility and Sterility, 2011Co-Authors: Michael Grynberg, Ana Luiza Berwanger, Meryl Toledano, Rene Frydman, X Deffieux, Renato FanchinAbstract:Objective To report a case of ureteral injury after transvaginal ultrasound-guided Oocyte Retrieval, initially misdiagnosed as an ovarian hyperstimulation syndrome (OHSS). Design Case report. Setting University hospital. Patient(s) A 26-year-old patient with a history of primary infertility due to polycystic ovary syndrome (PCOS) presented with acute pelvic pain after transvaginal ultrasound-guided Oocyte Retrieval for in vitro fertilization-embryo transfer. Intervention(s) Initial clinical presentation, context, and imaging results were consistent with the diagnosis of mild OHSS. Recurrence of the pelvic pain with radiation to the right lumbar region suggested the possibility of a urinary complication. Main Outcome Measure(s) Successful detection and management of unilateral ureteral injury in a patient with PCOS. Result(s) Uro-computed tomography scan helped with the diagnosis of right pelvic-ureter lesion. Patient underwent cystoscopy with uncomplicated right ureteral stent placement and delivered a healthy baby at term. Conclusion(s) Although ureteral injury after transvaginal ultrasound-guided Oocyte Retrieval is a rare complication of IVF-ET, it could have serious sequelae such as fistula formation and renal dysfunction if untreated. Clinicians must be aware that it may lurk undetected in women presenting OHSS.
Michael Grynberg - One of the best experts on this subject based on the ideXlab platform.
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ureteral injury after transvaginal ultrasound guided Oocyte Retrieval a complication of in vitro fertilization embryo transfer that may lurk undetected in women presenting with severe ovarian hyperstimulation syndrome
Fertility and Sterility, 2011Co-Authors: Michael Grynberg, Ana Luiza Berwanger, Meryl Toledano, Rene Frydman, X Deffieux, Renato FanchinAbstract:Objective To report a case of ureteral injury after transvaginal ultrasound-guided Oocyte Retrieval, initially misdiagnosed as an ovarian hyperstimulation syndrome (OHSS). Design Case report. Setting University hospital. Patient(s) A 26-year-old patient with a history of primary infertility due to polycystic ovary syndrome (PCOS) presented with acute pelvic pain after transvaginal ultrasound-guided Oocyte Retrieval for in vitro fertilization-embryo transfer. Intervention(s) Initial clinical presentation, context, and imaging results were consistent with the diagnosis of mild OHSS. Recurrence of the pelvic pain with radiation to the right lumbar region suggested the possibility of a urinary complication. Main Outcome Measure(s) Successful detection and management of unilateral ureteral injury in a patient with PCOS. Result(s) Uro-computed tomography scan helped with the diagnosis of right pelvic-ureter lesion. Patient underwent cystoscopy with uncomplicated right ureteral stent placement and delivered a healthy baby at term. Conclusion(s) Although ureteral injury after transvaginal ultrasound-guided Oocyte Retrieval is a rare complication of IVF-ET, it could have serious sequelae such as fistula formation and renal dysfunction if untreated. Clinicians must be aware that it may lurk undetected in women presenting OHSS.
Songying Zhang - One of the best experts on this subject based on the ideXlab platform.
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the effect of elevated progesterone levels before Oocyte Retrieval in women undergoing ovarian stimulation for ivf treatment on the genomic profile of peri implantation endometrium
Journal of Reproductive Immunology, 2017Co-Authors: Liu Liu, Jin Huang, Xu Tao Hong, S M Laird, Yong Dong Dai, Xiao Mei Tong, Haiyan Zhu, Songying ZhangAbstract:To evaluate the effects of high progesterone prior to Oocyte Retrieval on the genomic profile of peri-implantation endometrium, we conducted this single-center, prospective cohort study. Depending on whether or not the progesterone level on the day of hCG administration and the day after hCG administration were elevated, a total of 20 women undergoing IVF treatment who did not have fresh embryo transfer were included: Group 1 refers to subjects with normal progesterone level on both days; Group 2 refers to subjects with normal progesterone level on the day of hCG administration and high progesterone level on the day after hCG administration; Group 3 refers to subjects with high progesterone level on the day of hCG administration and normal progesterone level on the day after hCG administration; Group 4 refers to subjects with high progesterone level on both days. Five subjects were included in each group. Endometrial samples were obtained 7days after hCG administration. We found that high progesterone level prior to Oocyte Retrieval predominantly affected components of the NK cell mediated cytotoxicity pathway in the endometrium and that significant differences were only seen when progesterone measurements on both the day of and day after hCG administration were considered together.
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differential expression of vascular endothelial growth factor angiogenic factors in different endometrial compartments in women who have an elevated progesterone level before Oocyte Retrieval during in vitro fertilization embryo transfer treatment
Fertility and Sterility, 2015Co-Authors: Xiaoyan Chen, Xiaoying Jin, Liu Liu, Chi Wai Man, Jin Huang, Chi Chiu Wang, Songying ZhangAbstract:Objective To investigate the relationship between endometrial expressions of angiogenic factors around the time of embryo implantation and P level before Oocyte Retrieval during IVF-ET treatment. Design Retrospective study. Setting University Assisted Reproductive Unit. Patient(s) Forty patients were recruited, 20 women with an elevated P level, and 20 women with a normal P level, into cancelled embryo transfer (ET) cycles. Intervention(s) Endometrial biopsy samples were obtained from women who had an elevated or normal P level 7 days after human chorionic gonadotropin administration. The protein expression levels of VEGF-A, VEGF-C, and PLGF were examined using immunohistochemistry. Main Outcome Measure(s) A semiquantitative analysis was performed using histochemical-score analysis of staining intensity in the luminal epithelium, glandular epithelium, and stroma, separately. Result(s) Luminal epithelial expression of vascular endothelial growth factor (VEGF)-A, VEGF-C, and PLGF did not significantly differ in women with elevated or normal P levels before Oocyte Retrieval. Glandular epithelial expression of VEGF-A, VEGF-C, and PLGF was higher in women with elevated P levels, compared with those with normal P levels. A significantly higher stromal expression of VEGF-A and PLGF was found in women with elevated P levels. Conclusion(s) A high P level before Oocyte Retrieval was associated with expression of VEGF angiogenic factors in glandular epithelium and stromal compartment around the time of embryo implantation. Our findings suggest that the lower implantation rates observed in this group of women may relate to decreased endometrial receptivity arising from altered expression of angiogenic factors.
Seok Hyun Kim - One of the best experts on this subject based on the ideXlab platform.
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a case of empty follicle syndrome with successful Oocyte Retrieval by use of recombinant human chorionic gonadotropin
Obstetrics & gynecology science, 2005Co-Authors: Hee Seuong Kim, Su Jin Chai, Byung Chul Jee, Chang Suk Suh, Young Min Choi, Jung Gu Kim, Shin Yong Moon, Seok Hyun KimAbstract:It has been decades since the concept of empty follicle syndrome (EFS), in which no Oocytes are retrieved in an in vitro fertilization and embryo transfer (IVF-ET) cycle, was introduced. The incidence of this syndrome in patients undergoing IVF- ET has been estimated to be about 0.6-7%. The use of recombinant human chorionic gonadotropin (r-hCG) can be a useful option for the EFS patients with previous failure of Oocyte Retrieval in IVF-ET cycles. We present a case of empty follicle syndrome with successful Oocyte Retrieval by the use of r-hCG.
Benyu Miao - One of the best experts on this subject based on the ideXlab platform.
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a randomized double blind study to compare the effectiveness of three different doses of lignocaine used in paracervical block during Oocyte Retrieval
Journal of Assisted Reproduction and Genetics, 2003Co-Authors: Benyu MiaoAbstract:Purpose: To compare the effectiveness of three different doses of lignocaine used in paracervical block (PCB) during transvaginal ultrasound-guided Oocyte Retrieval (TUGOR) Methods: In this double-blind study, 153 patients undergoing TUGOR in their first in vitro fertilization cycle were randomized to receive 50, 100, and 150 mg of lignocaine in PCB. Pain levels were measured by a 100-mm linear visual analogue scale (0 = none to 100 = intolerable). Results: No differences were seen in the demographic data, the ovarian responses, the duration of TUGOR, and the number of follicles punctured. Vaginal and abdominal pain levels during TUGOR and 4 h after TUGOR were not significantly different among the three groups. The median vaginal and abdominal pain levels during the Retrieval were 22.0–24.0 and 30.0–32.0 respectively. Conclusions: The use of 50 mg of lignocaine is recommended in PCB because of the lack of improvement in pain relief on higher doses and potential dose-related risks.
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anxiolytic premedication reduces preoperative anxiety and pain during Oocyte Retrieval a randomized double blinded placebo controlled trial
Human Reproduction, 2002Co-Authors: Benyu MiaoAbstract:BACKGROUND: The role of anxiolytic premedication remains unclear and significant postoperative side-effects may result from routine use. METHODS: In this double-blinded study, 100 infertile patients were randomized on the day of ultrasound-guided Oocyte Retrieval (TUGOR) by a computer-generated randomization list in sealed envelopes to receive either (i) 50 mg pethidine and 25 mg promethazine (premedication group) or (ii) normal saline (placebo group) i.m. 30 min prior to TUGOR. Anxiety level, pain levels and severity of postoperative side-effects were recorded. RESULTS: No differences were seen in demographic data, TUGOR duration, number of follicles punctured and clinical outcome. Preoperative anxiety level was significantly higher than the basal anxiety level in the placebo group only. The vaginal and abdominal pain levels during TUGOR and 4 h after TUGOR were significantly higher in the placebo group than the premedication group. Significantly more patients complained of drowsiness after TUGOR in the premedication group than the placebo group and other side-effects were comparable in both groups. CONCLUSION: Routine use of anxiolytic premedication prevented an increase of preoperative anxiety level, reduced pain levels during Oocyte Retrieval but was associated with a higher percentage of moderate/ severe drowsiness in the postoperative period.