The Experts below are selected from a list of 42936 Experts worldwide ranked by ideXlab platform
Ruth D Williams - One of the best experts on this subject based on the ideXlab platform.
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primary Open Angle Glaucoma preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
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primary Open Angle Glaucoma suspect preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma suspect with detailed recommendations for evaluation and treatment options.
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Primary Open-Angle Glaucoma Preferred Practice Pattern(®) Guidelines.
Ophthalmology, 2015Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
Bruce E Prum - One of the best experts on this subject based on the ideXlab platform.
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primary Open Angle Glaucoma preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
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primary Open Angle Glaucoma suspect preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma suspect with detailed recommendations for evaluation and treatment options.
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Primary Open-Angle Glaucoma Preferred Practice Pattern(®) Guidelines.
Ophthalmology, 2015Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
Joan Dupont - One of the best experts on this subject based on the ideXlab platform.
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optic nerve blood flow is diminished in eyes of primary Open Angle Glaucoma suspects
American Journal of Ophthalmology, 2001Co-Authors: Jody R Piltzseymour, Juan E Grunwald, Seenu M Hariprasad, Joan DupontAbstract:Abstract PURPOSE: The purpose of this study was to evaluate optic nerve blood flow in primary Open-Angle Glaucoma suspect eyes with normal automated visual fields, in an attempt to elucidate how early in the Glaucomatous disease process changes in optic nerve blood flow become apparent. METHODS: Twenty-one eyes (21 patients) suspected of having primary Open-Angle Glaucoma were studied prospectively and compared with a previously reported cohort of 22 eyes (22 patients) with primary Open-Angle Glaucoma and 15 eyes (15 subjects) of age-matched controls. Primary Open-Angle Glaucoma suspect eyes had untreated intraocular pressure greater than 21 mm Hg and normal visual fields using Humphrey program 24-2 or 30-2 with a full threshold strategy. Laser Doppler flowmetry was used to measure optic nerve head blood velocity, volume, and flow at four quadrants in the optic nerve, in the cup, and in the foveola of one eye of each patient. The mean flow from the superotemporal rim, inferotemporal rim, and cup was calculated (Flow 3 ) and identified as the main outcome measure. Measurements from primary Open-Angle Glaucoma suspect eyes were compared with corresponding measurements from controls and eyes with primary Open-Angle Glaucoma; a Student t test was employed with a Bonferroni corrected P value of .025 to account for comparisons of primary Open-Angle Glaucoma suspects both to controls and to eyes with primary Open-Angle Glaucoma. RESULTS: Compared with controls, Flow 3 was 24% lower in primary Open-Angle Glaucoma suspect eyes ( P P P P CONCLUSIONS: Laser Doppler flowmetry detected circulatory abnormalities in primary Open-Angle Glaucoma suspects who did not have any manifest visual field defect. Decreases in flow in Glaucoma suspects were similar in magnitude to those of subjects with primary Open-Angle Glaucoma. These data suggest that impaired optic nerve blood flow develops early in the Glaucomatous process and does not develop solely as a result of Glaucoma damage.
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Optic nerve blood flow is diminished in eyes of primary Open-Angle Glaucoma suspects.
American journal of ophthalmology, 2001Co-Authors: Jody R. Piltz-seymour, Juan E Grunwald, Seenu M Hariprasad, Joan DupontAbstract:Abstract PURPOSE: The purpose of this study was to evaluate optic nerve blood flow in primary Open-Angle Glaucoma suspect eyes with normal automated visual fields, in an attempt to elucidate how early in the Glaucomatous disease process changes in optic nerve blood flow become apparent. METHODS: Twenty-one eyes (21 patients) suspected of having primary Open-Angle Glaucoma were studied prospectively and compared with a previously reported cohort of 22 eyes (22 patients) with primary Open-Angle Glaucoma and 15 eyes (15 subjects) of age-matched controls. Primary Open-Angle Glaucoma suspect eyes had untreated intraocular pressure greater than 21 mm Hg and normal visual fields using Humphrey program 24-2 or 30-2 with a full threshold strategy. Laser Doppler flowmetry was used to measure optic nerve head blood velocity, volume, and flow at four quadrants in the optic nerve, in the cup, and in the foveola of one eye of each patient. The mean flow from the superotemporal rim, inferotemporal rim, and cup was calculated (Flow 3 ) and identified as the main outcome measure. Measurements from primary Open-Angle Glaucoma suspect eyes were compared with corresponding measurements from controls and eyes with primary Open-Angle Glaucoma; a Student t test was employed with a Bonferroni corrected P value of .025 to account for comparisons of primary Open-Angle Glaucoma suspects both to controls and to eyes with primary Open-Angle Glaucoma. RESULTS: Compared with controls, Flow 3 was 24% lower in primary Open-Angle Glaucoma suspect eyes ( P P P P CONCLUSIONS: Laser Doppler flowmetry detected circulatory abnormalities in primary Open-Angle Glaucoma suspects who did not have any manifest visual field defect. Decreases in flow in Glaucoma suspects were similar in magnitude to those of subjects with primary Open-Angle Glaucoma. These data suggest that impaired optic nerve blood flow develops early in the Glaucomatous process and does not develop solely as a result of Glaucoma damage.
Sayoko E Moroi - One of the best experts on this subject based on the ideXlab platform.
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primary Open Angle Glaucoma preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
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primary Open Angle Glaucoma suspect preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma suspect with detailed recommendations for evaluation and treatment options.
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Primary Open-Angle Glaucoma Preferred Practice Pattern(®) Guidelines.
Ophthalmology, 2015Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
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Age-dependent prevalence of mutations at the GLC1A locus in primary Open-Angle Glaucoma.
American journal of ophthalmology, 2000Co-Authors: Satoko Shimizu, Sayoko E Moroi, Paul R. Lichter, A. Tim Johnson, Zhaohui Zhou, Misao Higashi, Maria Soffia Gottfredsdottir, Mohammad Othman, Frank W. Rozsa, Robert M SchertzerAbstract:c PURPOSE: To screen a population with primary OpenAngle Glaucoma for mutations in the gene that encodes the trabecular meshwork inducible glucocorticoid response protein (TIGR), also known as myocilin (MYOC). c METHODS: Ophthalmologic information was collected for study subjects with primary Open-Angle Glaucoma and their relatives. Mutation screening of 74 primary OpenAngle Glaucoma probands was conducted by sequencing TIGR/MYOC coding sequence and splice sites. c RESULTS: In 23 families we detected 13 nonsynonymous sequence changes, nine of which appear to be mutations likely to cause or contribute to primary OpenAngle Glaucoma. Two mutations, Arg272Gly and Ile499Ser, and one nonsynonymous sequence variant, Asn57Asp, are novel. We found mutations in nine of 25 juvenile Glaucoma probands (36%) and two of 49 adultonset Glaucoma probands (4%). Age classification of families rather than individual probands revealed mutations in three of nine families with strictly juvenile primary Open-Angle Glaucoma (33%), and no mutations in 39 families with strictly adult-onset primary Open-Angle Glaucoma (0%). In families with mixed-onset primary Open-Angle Glaucoma containing both juvenile primary Open-Angle Glaucoma and adult-onset primary Open-Angle Glaucoma cases, we found mutations in eight of 26 families (31%). c CONCLUSIONS: Our data suggest that Gly252Arg, Arg272Gly, Glu323Lys, Gln368STOP, Pro370Leu, Thr377Met, Val426Phe, Ile477Asn, and Ile499Ser are likely to play roles that cause or contribute to the etiology of autosomal dominant primary Open-Angle Glaucoma. Our finding of more TIGR/MYOC mutations in families with mixed-onset primary Open-Angle Glaucoma than in the families with strictly adult-onset primary Open-Angle Glaucoma implies that the presence of relatives with juvenile primary Open-Angle Glaucoma in a family could be used as a basis for identifying a subset of the population with adult-onset primary Open-Angle Glaucoma with higher prevalence of TIGR/MYOC mutations. To address this issue, and to refine estimations of mutation prevalence in these age-defined subpopulations, prospective study of a larger population ascertained entirely through adult-onset primary Open-Angle Glaucoma probands will be needed. (Am J Ophthalmol 2000;130: 165‐177. © 2000 by Elsevier Science Inc. All rights reserved.)
Steven L Mansberger - One of the best experts on this subject based on the ideXlab platform.
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primary Open Angle Glaucoma preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
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primary Open Angle Glaucoma suspect preferred practice pattern guidelines
Ophthalmology, 2016Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma suspect with detailed recommendations for evaluation and treatment options.
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Primary Open-Angle Glaucoma Preferred Practice Pattern(®) Guidelines.
Ophthalmology, 2015Co-Authors: Bruce E Prum, Lisa F Rosenberg, Steven J Gedde, Steven L Mansberger, Joshua D Stein, Sayoko E Moroi, Leon W Herndon, Michele C Lim, Ruth D WilliamsAbstract:Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary Open-Angle Glaucoma with an algorithm for patient management and detailed recommendations for evaluation and treatment options.
