The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform

Lisa Harder - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018
    Co-Authors: Ann-kathrin Bodenstein, Matthias Lüpke, Christian Seiler, Frank Goblet, Stephan Nikolic, Ulf Hinze, Boris Chichkov, Claudia Windhövel, Jan-peter Bach, Lisa Harder
    Abstract:

     The purpose of this study is to analyze the static magnetic field interactions for an ophthalmic-magnetic shunt Implant with a ferromagnetic steel plate in a thin silicon layer. The plate is used for opening of a valve flap. Ten different sizes of this steel plate were investigated to characterize the relationship between the size of the metal and the magnetic forces of the static magnetic field of a 3.0 T MRI.  The magnetic translation force Fz was quantified by determining the deflection angle using the deflection angle test (ASTM F 2052). The torque was qualitatively estimated by using a 5-point grading scale (0: no torque; + 4: very strong torque) according to Sommer et al. 11. For the visual investigation of the function of the metal plate both prototypes were positioned at the magnetic field's spatial gradient and at the magnet's isocenter. The stitches were exposed to the thousandfold of the translational force by a dynamometer.  The translational force was found to be 10 times greater than the weight of a single plate. The plates were exposed to a high torque (grade 3 to 4). The seams and the tissue withstood more than a thousandfold of the determined translational force. No spontaneous, uncontrolled opening of the valve flap was visible in the MRI, as a result of which the intraocular pressure could decrease considerably.  Due to the small size of the plates the translational force and the torque will be compensated by the silicon layer and also by the fixation in the eye.   · Magnetic forces will be compensated by silicon layer and fixation in the eye.. · The magnetic-Ophthalmological Implant is not restricted in its function by the MRI magnetic field.. · The ophthalmic magnetic shunt Implant can be considered conditionally MRI-safe.. · Bodenstein A, Lüpke M, Seiler C et al. Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI. Fortschr Röntgenstr 2019; 191: 209 - 215. © Georg Thieme Verlag KG Stuttgart · New York.

Howard Diamond - One of the best experts on this subject based on the ideXlab platform.

  • Ophthalmological Implant and method for sustained release of medication to the eye
    2000
    Co-Authors: Bruce E Cohan, Howard Diamond
    Abstract:

    ophthalmologic Implant for sustained release of medication to an eye, comprising: a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of an eyelid; a collarette connected to the body portion and sized to rest on the exterior of the lacrimal punctum, the collarette having at least one pore provided therein; a reservoir contained at least partially within the body portion and in fluid communication with the at least one pore; and a medication stored within the reservoir and released through the at least one pore and onto the eye over time in a controlled manner while the insert is positioned in the eyelid.

Ann-kathrin Bodenstein - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018
    Co-Authors: Ann-kathrin Bodenstein, Matthias Lüpke, Christian Seiler, Frank Goblet, Stephan Nikolic, Ulf Hinze, Boris Chichkov, Claudia Windhövel, Jan-peter Bach, Lisa Harder
    Abstract:

     The purpose of this study is to analyze the static magnetic field interactions for an ophthalmic-magnetic shunt Implant with a ferromagnetic steel plate in a thin silicon layer. The plate is used for opening of a valve flap. Ten different sizes of this steel plate were investigated to characterize the relationship between the size of the metal and the magnetic forces of the static magnetic field of a 3.0 T MRI.  The magnetic translation force Fz was quantified by determining the deflection angle using the deflection angle test (ASTM F 2052). The torque was qualitatively estimated by using a 5-point grading scale (0: no torque; + 4: very strong torque) according to Sommer et al. 11. For the visual investigation of the function of the metal plate both prototypes were positioned at the magnetic field's spatial gradient and at the magnet's isocenter. The stitches were exposed to the thousandfold of the translational force by a dynamometer.  The translational force was found to be 10 times greater than the weight of a single plate. The plates were exposed to a high torque (grade 3 to 4). The seams and the tissue withstood more than a thousandfold of the determined translational force. No spontaneous, uncontrolled opening of the valve flap was visible in the MRI, as a result of which the intraocular pressure could decrease considerably.  Due to the small size of the plates the translational force and the torque will be compensated by the silicon layer and also by the fixation in the eye.   · Magnetic forces will be compensated by silicon layer and fixation in the eye.. · The magnetic-Ophthalmological Implant is not restricted in its function by the MRI magnetic field.. · The ophthalmic magnetic shunt Implant can be considered conditionally MRI-safe.. · Bodenstein A, Lüpke M, Seiler C et al. Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI. Fortschr Röntgenstr 2019; 191: 209 - 215. © Georg Thieme Verlag KG Stuttgart · New York.

Bruce E Cohan - One of the best experts on this subject based on the ideXlab platform.

  • Ophthalmological Implant and method for sustained release of medication to the eye
    2000
    Co-Authors: Bruce E Cohan, Howard Diamond
    Abstract:

    ophthalmologic Implant for sustained release of medication to an eye, comprising: a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of an eyelid; a collarette connected to the body portion and sized to rest on the exterior of the lacrimal punctum, the collarette having at least one pore provided therein; a reservoir contained at least partially within the body portion and in fluid communication with the at least one pore; and a medication stored within the reservoir and released through the at least one pore and onto the eye over time in a controlled manner while the insert is positioned in the eyelid.

Matthias Lüpke - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018
    Co-Authors: Ann-kathrin Bodenstein, Matthias Lüpke, Christian Seiler, Frank Goblet, Stephan Nikolic, Ulf Hinze, Boris Chichkov, Claudia Windhövel, Jan-peter Bach, Lisa Harder
    Abstract:

     The purpose of this study is to analyze the static magnetic field interactions for an ophthalmic-magnetic shunt Implant with a ferromagnetic steel plate in a thin silicon layer. The plate is used for opening of a valve flap. Ten different sizes of this steel plate were investigated to characterize the relationship between the size of the metal and the magnetic forces of the static magnetic field of a 3.0 T MRI.  The magnetic translation force Fz was quantified by determining the deflection angle using the deflection angle test (ASTM F 2052). The torque was qualitatively estimated by using a 5-point grading scale (0: no torque; + 4: very strong torque) according to Sommer et al. 11. For the visual investigation of the function of the metal plate both prototypes were positioned at the magnetic field's spatial gradient and at the magnet's isocenter. The stitches were exposed to the thousandfold of the translational force by a dynamometer.  The translational force was found to be 10 times greater than the weight of a single plate. The plates were exposed to a high torque (grade 3 to 4). The seams and the tissue withstood more than a thousandfold of the determined translational force. No spontaneous, uncontrolled opening of the valve flap was visible in the MRI, as a result of which the intraocular pressure could decrease considerably.  Due to the small size of the plates the translational force and the torque will be compensated by the silicon layer and also by the fixation in the eye.   · Magnetic forces will be compensated by silicon layer and fixation in the eye.. · The magnetic-Ophthalmological Implant is not restricted in its function by the MRI magnetic field.. · The ophthalmic magnetic shunt Implant can be considered conditionally MRI-safe.. · Bodenstein A, Lüpke M, Seiler C et al. Evaluation of the static magnetic field interactions for a newly developed magnetic ophthalmic Implant at 3 Tesla MRI. Fortschr Röntgenstr 2019; 191: 209 - 215. © Georg Thieme Verlag KG Stuttgart · New York.