The Experts below are selected from a list of 29271 Experts worldwide ranked by ideXlab platform
Victor Soltwisch - One of the best experts on this subject based on the ideXlab platform.
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applicability of the debye waller damping factor for the determination of the line edge roughness of lamellar gratings
Optics Express, 2019Co-Authors: Analia Fernandez Herrero, Mika Pfluger, Jurgen Probst, Frank Scholze, Victor SoltwischAbstract:Periodic nanostructures are fundamental elements in Optical Instrumentation as well as basis structures in integrated electronic circuits. Decreasing sizes and increasing complexity of nanostructures have made roughness a limiting parameter to the performance. Grazing-incidence small-angle X-ray scattering is a characterization method that is sensitive to three-dimensional structures and their imperfections. To quantify line-edge roughness, a Debye-Waller factor (DWF), which is derived for binary gratings, is usually used. In this work, we systematically analyze the effect of roughness on the diffracted intensities. Two different limits to the application of the DWF are found depending on whether the roughness is normally distributed or not.
Michael S Feld - One of the best experts on this subject based on the ideXlab platform.
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static and dynamic light scattering of healthy and malaria parasite invaded red blood cells
Journal of Biomedical Optics, 2010Co-Authors: Yongkeun Park, Gabriel Popescu, Monica Diezsilva, Dan Fu, Wonshik Choi, Ishan Barman, S Suresh, Michael S FeldAbstract:We present the light scattering of individual Plasmodium falciparum-parasitized human red blood cells Pf-RBCs, and demonstrate progressive alterations to the scattering signal arising from the development of malaria-inducing parasites. By selectively imaging the electric fields using quantitative phase microscopy and a Fourier transform light scattering technique, we calculate the light scattering maps of individual Pf-RBCs. We show that the onset and progression of pathological states of the Pf-RBCs can be clearly identified by the static scattering maps. Progressive changes to the biophysical properties of the Pf-RBC membrane are captured from dynamic light scattering. © 2010 Society of Photo-Optical Instrumentation Engineers.
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erythrocyte structure and dynamics quantified by hilbert phase microscopy
Journal of Biomedical Optics, 2005Co-Authors: Gabriel Popescu, Takahiro Ikeda, Kamra Adizadega, Ramachandra R Dasari, Michael S FeldAbstract:We present a new quantitative method for in- vestigating red blood cell morphology and dynamics. The instrument integrates quantitative phase microscopy with an inverted microscope, which makes it particularly suit- able for the noninvasive assessment of live erythrocytes. In particular, we demonstrate the ability of this approach to quantify noninvasively cell volume and dynamic mor- phology. The subnanometer path-length sensitivity at the millisecond time scales is exemplified by measuring the hemoglobin flow out of the cell during hemolysis. © 2005 Society of Photo-Optical Instrumentation Engineers. DOI: 10.1117/1.2149847
Rebecca Richardskortum - One of the best experts on this subject based on the ideXlab platform.
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fiber optic probes for biomedical Optical spectroscopy
Journal of Biomedical Optics, 2003Co-Authors: Urs Utzinger, Rebecca RichardskortumAbstract:Fiber optic probes are a key element for biomedical spec- troscopic sensing. We review the use of fiber optic probes for Optical spectroscopy, focusing on applications in turbid media, such as tissue. The design of probes for reflectance, polarized reflectance, fluores- cence, and Raman spectroscopy is illustrated. We cover universal de- sign principles as well as technologies for beam deflecting and re- shaping. © 2003 Society of Photo-Optical Instrumentation Engineers.
Analia Fernandez Herrero - One of the best experts on this subject based on the ideXlab platform.
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applicability of the debye waller damping factor for the determination of the line edge roughness of lamellar gratings
Optics Express, 2019Co-Authors: Analia Fernandez Herrero, Mika Pfluger, Jurgen Probst, Frank Scholze, Victor SoltwischAbstract:Periodic nanostructures are fundamental elements in Optical Instrumentation as well as basis structures in integrated electronic circuits. Decreasing sizes and increasing complexity of nanostructures have made roughness a limiting parameter to the performance. Grazing-incidence small-angle X-ray scattering is a characterization method that is sensitive to three-dimensional structures and their imperfections. To quantify line-edge roughness, a Debye-Waller factor (DWF), which is derived for binary gratings, is usually used. In this work, we systematically analyze the effect of roughness on the diffracted intensities. Two different limits to the application of the DWF are found depending on whether the roughness is normally distributed or not.
Yuanjin Zheng - One of the best experts on this subject based on the ideXlab platform.
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photoacoustic resonance spectroscopy for biological tissue characterization
Journal of Biomedical Optics, 2014Co-Authors: Fei Gao, Xiaohua Feng, Yuanjin Zheng, Clausdieter OhlAbstract:By "listening to photons," photoacoustics allows the probing of chromosomes in depth beyond the Optical diffusion limit. Here we report the photoacoustic resonance effect induced by multiburst modulated laser illumination, which is theoretically modeled as a damped mass-string oscillator and a resistor-inductor-capacitor (RLC) circuit. Through sweeping the frequency of multiburst modulated laser, the photoacoustic resonance effect is observed experimentally on phantoms and porcine tissues. Experimental results demonstrate different spectra for each phantom and tissue sample to show significant potential for spectroscopic analysis, fusing Optical absorption and mechanical vibration properties. Unique RLC circuit parameters are extracted to quanti- tatively characterize phantom and biological tissues. © 2014 Society of Photo-Optical Instrumentation Engineers (SPIE) (DOI: 10
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photoacoustic resonance spectroscopy for biological tissue characterization
Journal of Biomedical Optics, 2014Co-Authors: Xiaohua Feng, Yuanjin ZhengAbstract:By "listening to photons," photoacoustics allows the probing of chromosomes in depth beyond the Optical diffusion limit. Here we report the photoacoustic resonance effect induced by multiburst modulated laser illumination, which is theoretically modeled as a damped mass-string oscillator and a resistor-inductor-capacitor (RLC) circuit. Through sweeping the frequency of multiburst modulated laser, the photoacoustic resonance effect is observed experimentally on phantoms and porcine tissues. Experimental results demonstrate different spectra for each phantom and tissue sample to show significant potential for spectroscopic analysis, fusing Optical absorption and mechanical vibration properties. Unique RLC circuit parameters are extracted to quanti- tatively characterize phantom and biological tissues. © 2014 Society of Photo-Optical Instrumentation Engineers (SPIE) (DOI: 10