The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform
Isabel Fonseca - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of 2‘-Alkylspiro[2-X-cyclohexan-1,3‘-3‘H-indole] (X = H; X = CH3) by an Unexpected Reaction between an Organomagnesium Halide and 2‘-Methylspiro[2-X-cyclohexan-1,3‘-3‘H-indole]. X-ray Structure of a Fluorescent Dimeric Compound
Journal of Organic Chemistry, 1998Co-Authors: J. Gonzalo Rodriguez, Anahi Urrutia, J. Eugenio De Diego, ‡ And M. Paz Martínez-alcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
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synthesis of 2 alkylspiro 2 x cyclohexan 1 3 3 h indole x h x ch3 by an unexpected reaction between an Organomagnesium Halide and 2 methylspiro 2 x cyclohexan 1 3 3 h indole x ray structure of a fluorescent dimeric compound
Journal of Organic Chemistry, 1998Co-Authors: Gonzalo J Rodriguez, Anahi Urrutia, Eugenio J De Diego, And Paz M Martinezalcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
Gonzalo J Rodriguez - One of the best experts on this subject based on the ideXlab platform.
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synthesis of 2 alkylspiro 2 x cyclohexan 1 3 3 h indole x h x ch3 by an unexpected reaction between an Organomagnesium Halide and 2 methylspiro 2 x cyclohexan 1 3 3 h indole x ray structure of a fluorescent dimeric compound
Journal of Organic Chemistry, 1998Co-Authors: Gonzalo J Rodriguez, Anahi Urrutia, Eugenio J De Diego, And Paz M Martinezalcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
Anahi Urrutia - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of 2‘-Alkylspiro[2-X-cyclohexan-1,3‘-3‘H-indole] (X = H; X = CH3) by an Unexpected Reaction between an Organomagnesium Halide and 2‘-Methylspiro[2-X-cyclohexan-1,3‘-3‘H-indole]. X-ray Structure of a Fluorescent Dimeric Compound
Journal of Organic Chemistry, 1998Co-Authors: J. Gonzalo Rodriguez, Anahi Urrutia, J. Eugenio De Diego, ‡ And M. Paz Martínez-alcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
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synthesis of 2 alkylspiro 2 x cyclohexan 1 3 3 h indole x h x ch3 by an unexpected reaction between an Organomagnesium Halide and 2 methylspiro 2 x cyclohexan 1 3 3 h indole x ray structure of a fluorescent dimeric compound
Journal of Organic Chemistry, 1998Co-Authors: Gonzalo J Rodriguez, Anahi Urrutia, Eugenio J De Diego, And Paz M Martinezalcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
And Paz M Martinezalcazar - One of the best experts on this subject based on the ideXlab platform.
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synthesis of 2 alkylspiro 2 x cyclohexan 1 3 3 h indole x h x ch3 by an unexpected reaction between an Organomagnesium Halide and 2 methylspiro 2 x cyclohexan 1 3 3 h indole x ray structure of a fluorescent dimeric compound
Journal of Organic Chemistry, 1998Co-Authors: Gonzalo J Rodriguez, Anahi Urrutia, Eugenio J De Diego, And Paz M Martinezalcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.
Eugenio J De Diego - One of the best experts on this subject based on the ideXlab platform.
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synthesis of 2 alkylspiro 2 x cyclohexan 1 3 3 h indole x h x ch3 by an unexpected reaction between an Organomagnesium Halide and 2 methylspiro 2 x cyclohexan 1 3 3 h indole x ray structure of a fluorescent dimeric compound
Journal of Organic Chemistry, 1998Co-Authors: Gonzalo J Rodriguez, Anahi Urrutia, Eugenio J De Diego, And Paz M Martinezalcazar, Isabel FonsecaAbstract:The reaction of 2‘-methylspiro[cyclohexan-1,3‘-3‘H-indole] (1a) with methylmagnesium iodide gives 2‘-ethyl-, 2‘-isopropyl-, and 2‘-tert-butylspiro[cyclohexan-1,3‘-3‘H-indole] as the unexpected 2‘-methyl insertion products; their presence and ratio are dependent upon the reaction conditions. Influence of a methyl substituent in 2‘-methylspiro[2-methylcyclohexan-1,3‘-3‘H-indole] (1b) on the reaction with methylmagnesium iodide has been analyzed; the 2‘-ethyl (2b) and 2‘-isopropyl (3b) derivatives were obtained as the insertion products together with a luminescent compound that was identified by X-ray diffraction analysis as meso-(1R,2S),(1S,2R)-α,β-di{(2‘-(spiro[2-methylcyclohexan-1,3‘-3'H-indolyl]}ethene (10). The reaction of 1a or 1b with some active Organomagnesium Halides (allyl or benzyl) afforded the 2‘-methyl-2‘-alkyl-3‘H-indole derivative (allyl, 5a or 5b; benzyl, 6a) as an apparent addition product. The reaction possibly occurs through a mechanism of radical intermediates.