The Experts below are selected from a list of 141 Experts worldwide ranked by ideXlab platform
A. L. B. Pinheiro - One of the best experts on this subject based on the ideXlab platform.
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Clinical study on the efficacy of LED phototherapy for pain control in an Orthodontic Procedure
Lasers in Medical Science, 2019Co-Authors: I. Z. Figueira, A. P. C Sousa, A. W Machado, F. A. L. Habib, L. G. P. Soares, A. L. B. PinheiroAbstract:Pain is an unpleasant and emotional subjective sensory experience that occurs during Orthodontic Procedures. Currently, LED phototherapy is an alternative to the use of laser light as analgesic agent due to similarity of response and lower cost. This case-control, quantitative, qualitative, and longitudinal study aimed to investigate the effect of IR LED phototherapy (λ846 ± 20 nm) in pain during the process of tooth separation during Orthodontic treatment. After approval by the Institution Ethics Committee, 40 patients (30 female/10 male, 20–30 years old, average age 24.5 ± 2.6 years old) fulfilling the inclusion criteria entered the study and received a set of four visual analog scales (VAS) for scoring pain immediately, 48 h, 72 h, and 7 days after the insertion of the separating elastics. The patients were randomly distributed into two groups (experimental and control). The patients of experimental group received LED phototherapy (180 mW, 22 s, 4 J, 8 J/cm^2_, 0.36 W/cm^2, spot of 0.5 cm^2, spot diameter 0.8 cm) at the same times in which VAS was performed, and control patients were not irradiated. It was found that, in both groups, there was an increase in pain 48 h after insertion of the elastic tooth separator, decreasing 72 h after its installation and reached the lowest level of pain after 7 days. Comparison between groups showed that pain level in the LED group was always statistically significantly lower ( p
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clinical study on the efficacy of led phototherapy for pain control in an Orthodontic Procedure
Lasers in Medical Science, 2019Co-Authors: I. Z. Figueira, A. P. C Sousa, A. W Machado, F. A. L. Habib, L. G. P. Soares, A. L. B. PinheiroAbstract:Pain is an unpleasant and emotional subjective sensory experience that occurs during Orthodontic Procedures. Currently, LED phototherapy is an alternative to the use of laser light as analgesic agent due to similarity of response and lower cost. This case-control, quantitative, qualitative, and longitudinal study aimed to investigate the effect of IR LED phototherapy (λ846 ± 20 nm) in pain during the process of tooth separation during Orthodontic treatment. After approval by the Institution Ethics Committee, 40 patients (30 female/10 male, 20-30 years old, average age 24.5 ± 2.6 years old) fulfilling the inclusion criteria entered the study and received a set of four visual analog scales (VAS) for scoring pain immediately, 48 h, 72 h, and 7 days after the insertion of the separating elastics. The patients were randomly distributed into two groups (experimental and control). The patients of experimental group received LED phototherapy (180 mW, 22 s, 4 J, 8 J/cm2, 0.36 W/cm2, spot of 0.5 cm2, spot diameter 0.8 cm) at the same times in which VAS was performed, and control patients were not irradiated. It was found that, in both groups, there was an increase in pain 48 h after insertion of the elastic tooth separator, decreasing 72 h after its installation and reached the lowest level of pain after 7 days. Comparison between groups showed that pain level in the LED group was always statistically significantly lower (p < 0.05), except for the time of installation (T1). The use of LED light was effective in significantly reducing the level of pain after insertion of the elastic tooth separators when compared to the control group.
Emília Ângela Lo Schiavo Arisawa - One of the best experts on this subject based on the ideXlab platform.
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The effect of two phototherapy protocols on pain control in Orthodontic Procedure—a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm^2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm^2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.
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the effect of two phototherapy protocols on pain control in Orthodontic Procedure a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.
Maria Ângela Lacerda Rangel Esper - One of the best experts on this subject based on the ideXlab platform.
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The effect of two phototherapy protocols on pain control in Orthodontic Procedure—a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm^2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm^2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.
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the effect of two phototherapy protocols on pain control in Orthodontic Procedure a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.
Massieh Moayedi - One of the best experts on this subject based on the ideXlab platform.
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baseline resting state functional connectivity determines subsequent pain ratings to a tonic ecologically valid experimental model of orofacial pain
bioRxiv, 2020Co-Authors: Lizbeth J Ayoub, Mary Pat Mcandrews, Alexander Barnett, Iacopo Cioffi, Massieh MoayediAbstract:Pain is a subjective experience with significant individual differences. Laboratory studies investigating pain thresholds and experimental acute pain have identified structural and functional neural correlates. However, these types of pain stimuli have limited ecological validity to real-life pain experiences. Here, we use an Orthodontic Procedure--the insertion of an elastomeric separator between teeth--which typically induces mild to moderate pain that peaks within 2 days and lasts several days. We aimed to determine whether the baseline structure and resting-state functional connectivity (rsFC) of key regions along the trigeminal nociceptive and pain modulatory pathways correlate with subsequent peak pain ratings. Twenty-six healthy individuals underwent structural and resting-state functional (rs-fMRI) scanning prior to the placement of a separator between the first and second molars, which was kept in place for five days. Participants recorded pain ratings three times daily on a 100-mm visual analogue scale. Peak pain was not significantly correlated with diffusion metrics of the trigeminal nerve, or grey matter volume of any brain region. Peak pain did, however, positively correlate with baseline rsFC between the thalamus contralateral to the separator and bilateral insula, and negatively correlated with connectivity between the periaqueductal gray (PAG) and core nodes of the default mode network (medial prefrontal and posterior cingulate cortices). The ascending (thalamic) nociceptive and the descending (PAG) pain modulatory pathways at baseline each explained unique variation in peak pain intensity ratings. In sum, pre-interventional functional neural architecture of both systems determined the individual pain experience to a subsequent ecologically valid pain stimulus.
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resting state functional connectivity predicts individual pain ratings to a tonic orofacial pain stimulus
bioRxiv, 2020Co-Authors: Lizbeth J Ayoub, Mary Pat Mcandrews, Alexander Barnett, Iacopo Cioffi, Massieh MoayediAbstract:Pain is a subjective experience with significant individual differences. Laboratory studies investigating pain thresholds and acute pain have identified structural and functional neural correlates. However, these types of pain stimuli have limited ecological validity to real-life pain experience. Here, we use an Orthodontic Procedure which typically induces pain lasting several days. We aimed to determine whether the baseline structure and resting-state functional connectivity (rsFC) of key regions along the trigeminal nociceptive and pain modulatory pathways correlate with subsequent peak pain ratings. Twenty-six healthy individuals underwent structural (T1, diffusion-weighted MRI) and resting-state functional magnetic resonance imaging (rs-fMRI) scanning prior to the Orthodontic Procedure, the insertion of an elastomeric separator between teeth, for five days. Participants recorded pain ratings three times, daily. Peak pain was not correlated with structural measures for the trigeminal nerve or any brain region. However, peak pain correlated with rsFC between the contralateral thalamus and bilateral insula, and negatively correlated with connectivity between the periaqueductal gray and core nodes of the default mode network (medial prefrontal and posterior cingulate cortices). In this ecologically valid model, we demonstrate that both ascending nociceptive and descending pain modulatory pathways shape the individual pain experience.
Renata Amadei Nicolau - One of the best experts on this subject based on the ideXlab platform.
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The effect of two phototherapy protocols on pain control in Orthodontic Procedure—a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm^2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm^2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.
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the effect of two phototherapy protocols on pain control in Orthodontic Procedure a preliminary clinical study
Lasers in Medical Science, 2011Co-Authors: Maria Ângela Lacerda Rangel Esper, Renata Amadei Nicolau, Emília Ângela Lo Schiavo ArisawaAbstract:Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in Orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after Orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm2, 0.10 W, 70 s). Separators were used to induce Orthodontic pain and the volunteers pain levels were scored with the visual analog scale (VAS) after the separator placement, after the therapy (placebo, laser, or LED), and after 2, 24, 48, 72, 96, and 120 h. The laser group did not have statistically significant results in the reduction of pain level compared to the LED group. The LED group had a significant reduction in pain levels between 2 and 120 h compared to the control and the laser groups. The LED therapy showed a significant reduction in pain sensitivity (an average of 56%), after the Orthodontic tooth movement when compared to the control group.