The Experts below are selected from a list of 39 Experts worldwide ranked by ideXlab platform
Samanthi Wickramasekara - One of the best experts on this subject based on the ideXlab platform.
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Screening for extractables in additive-manufactured acrylonitrile butadiene styrene Orthopedic Cast.
Talanta, 2020Co-Authors: Keaton Nahan, Eric M. Sussman, Berk Oktem, Lester Schultheis, Samanthi WickramasekaraAbstract:Abstract The use of additive-manufactured components in medical applications, specifically medical devices (e.g., Orthopedic Casts), has increased in recent years. Such devices may be fabricated at the point of care using consumer-grade additive manufacturing. Limited studies have been conducted to evaluate the extractable substances of these devices. Chemical characterization followed by toxicological risk assessment is one means of evaluating safety of devices. This study was designed to determine the extractables profile of additive-manufactured materials according to filament grade and post-processing method. Feedstocks for additive manufacturing were tested as filament and manufactured Casts, while the Cast from consumer-grade filament (CGF) was post-processed. Samples were extracted using three solvents of varying polarities. Extracts were analyzed by gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) techniques. In GC/MS analysis, isopropanol extracts generated fewer compound identifications for USP Class VI filament (USPF)-based Casts (3) compared with the respective filament (17) while hexane generated the most compound identifications for the finished Cast manufactured from CGF. CGF was found to have the highest number of nonvolatile extractables for isopropanol (15) and hexane (34) by positive ion LC/MS. Additionally, CGF produced more non-polar extractables in hexane than the USPF. A known polymer byproduct and potential genotoxicant, styrene acrylonitrile (SAN) trimer, was one of the compounds identified in both GC/MS and LC/MS at quantities ranging from 19 to 270 μg g−1. Overall these results suggested that the extractables profile was affected by the filament material, printing procedure, and post-processing method.
Carson Andrew Umsted - One of the best experts on this subject based on the ideXlab platform.
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textile based sensor development for the continuous monitoring of proper Orthopedic Cast fit
2013Co-Authors: Carson Andrew UmstedAbstract:The ability to determine the level of support a Cast provides to a fractured arm through the course of healing does not currently exist yet is very useful information in being proactive to make adjustments to the fit of the Cast. The method to which these measurements can occur is constrained by the physician's constraints which require a non-invasive, compact solution that can continuously monitor the level of support at a reasonable interval while maintaining a simple and low-cost implementation. These objectives require the use of the latest in textile innovation. The SmartCast system utilizes textile properties to create pressure resistive sensors that can be directly placed between the injured arm and the Cast while not impacting patient comfort. The development of this system has allowed the provision of level of support information validated with the initial Cast-based tests.
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textile based sensor development for the continuous monitoring of proper Orthopedic Cast fit escholarship
2013Co-Authors: Carson Andrew UmstedAbstract:The ability to determine the level of support a Cast provides to a fractured arm through the course of healing does not currently exist yet is very useful information in being proactive to make adjustments to the fit of the Cast. The method to which these measurements can occur is constrained by the physician's constraints which require a non-invasive, compact solution that can continuously monitor the level of support at a reasonable interval while maintaining a simple and low-cost implementation. These objectives require the use of the latest in textile innovation. The SmartCast system utilizes textile properties to create pressure resistive sensors that can be directly placed between the injured arm and the Cast while not impacting patient comfort. The development of this system has allowed the provision of level of support information validated with the initial Cast-based tests.
Keaton Nahan - One of the best experts on this subject based on the ideXlab platform.
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Screening for extractables in additive-manufactured acrylonitrile butadiene styrene Orthopedic Cast.
Talanta, 2020Co-Authors: Keaton Nahan, Eric M. Sussman, Berk Oktem, Lester Schultheis, Samanthi WickramasekaraAbstract:Abstract The use of additive-manufactured components in medical applications, specifically medical devices (e.g., Orthopedic Casts), has increased in recent years. Such devices may be fabricated at the point of care using consumer-grade additive manufacturing. Limited studies have been conducted to evaluate the extractable substances of these devices. Chemical characterization followed by toxicological risk assessment is one means of evaluating safety of devices. This study was designed to determine the extractables profile of additive-manufactured materials according to filament grade and post-processing method. Feedstocks for additive manufacturing were tested as filament and manufactured Casts, while the Cast from consumer-grade filament (CGF) was post-processed. Samples were extracted using three solvents of varying polarities. Extracts were analyzed by gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) techniques. In GC/MS analysis, isopropanol extracts generated fewer compound identifications for USP Class VI filament (USPF)-based Casts (3) compared with the respective filament (17) while hexane generated the most compound identifications for the finished Cast manufactured from CGF. CGF was found to have the highest number of nonvolatile extractables for isopropanol (15) and hexane (34) by positive ion LC/MS. Additionally, CGF produced more non-polar extractables in hexane than the USPF. A known polymer byproduct and potential genotoxicant, styrene acrylonitrile (SAN) trimer, was one of the compounds identified in both GC/MS and LC/MS at quantities ranging from 19 to 270 μg g−1. Overall these results suggested that the extractables profile was affected by the filament material, printing procedure, and post-processing method.
Robert Shorten - One of the best experts on this subject based on the ideXlab platform.
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i nteract a cyber physical system for real time interaction with physical and virtual objects using mixed reality technologies for additive manufacturing
arXiv: Human-Computer Interaction, 2020Co-Authors: Ammar Malik, Hugo Lhachemi, Robert ShortenAbstract:This paper presents I-nteract, a cyber-physical system that enables real-time interaction with real and virtual objects in a mixed augmented reality environment to design 3D models for additive manufacturing. The system has been developed using mixed reality technologies such as HoloLens, for augmenting visual feedback, and haptic gloves, for augmenting haptic force feedback. The efficacy of the system has been demonstrated by generating 3D model using a novel scanning method to 3D print a customized Orthopedic Cast for human arm, by estimating spring rates of compression springs, and by simulating interaction with a virtual spring using hand.
Eric M. Sussman - One of the best experts on this subject based on the ideXlab platform.
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Screening for extractables in additive-manufactured acrylonitrile butadiene styrene Orthopedic Cast.
Talanta, 2020Co-Authors: Keaton Nahan, Eric M. Sussman, Berk Oktem, Lester Schultheis, Samanthi WickramasekaraAbstract:Abstract The use of additive-manufactured components in medical applications, specifically medical devices (e.g., Orthopedic Casts), has increased in recent years. Such devices may be fabricated at the point of care using consumer-grade additive manufacturing. Limited studies have been conducted to evaluate the extractable substances of these devices. Chemical characterization followed by toxicological risk assessment is one means of evaluating safety of devices. This study was designed to determine the extractables profile of additive-manufactured materials according to filament grade and post-processing method. Feedstocks for additive manufacturing were tested as filament and manufactured Casts, while the Cast from consumer-grade filament (CGF) was post-processed. Samples were extracted using three solvents of varying polarities. Extracts were analyzed by gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) techniques. In GC/MS analysis, isopropanol extracts generated fewer compound identifications for USP Class VI filament (USPF)-based Casts (3) compared with the respective filament (17) while hexane generated the most compound identifications for the finished Cast manufactured from CGF. CGF was found to have the highest number of nonvolatile extractables for isopropanol (15) and hexane (34) by positive ion LC/MS. Additionally, CGF produced more non-polar extractables in hexane than the USPF. A known polymer byproduct and potential genotoxicant, styrene acrylonitrile (SAN) trimer, was one of the compounds identified in both GC/MS and LC/MS at quantities ranging from 19 to 270 μg g−1. Overall these results suggested that the extractables profile was affected by the filament material, printing procedure, and post-processing method.
