Orthopedic Oncologist

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Jose Juan Pozo Kreilinger - One of the best experts on this subject based on the ideXlab platform.

  • enchondroma versus chondrosarcoma in long bones of appendicular skeleton clinical and radiological criteria a follow up
    Journal of Oncology, 2016
    Co-Authors: Eugenio M Ferrersantacreu, Mariana Diazalmiron, Eduardo J Ortizcruz, Jose Juan Pozo Kreilinger
    Abstract:

    As of today two types of cartilage tumors remain a challenge even for the Orthopedic Oncologist: enchondroma (E), a benign tumor, and chondrosarcoma (LGC), a malignant and low aggressiveness tumor. A prospective study of 133 patients with a cartilaginous tumor of low aggressiveness in the long bones of the appendicular skeleton was done to prove this difficult differential diagnosis. Parameters including medical history and radiological and nuclear imaging were collected and compared to the result of the biopsy. A scale of aggressiveness was applied to each patient according to the number of aggressiveness episodes present. A comparison of the results of the biopsy with the initial diagnosis made by the Orthopedic Oncologist based solely on clinical data and imaging tests was also made. Finally, a management algorithm for these cases was proposed. A statistical significance for LGC resulted from the parameter as follows: pain on palpation, involvement of cortical in either the CT or MRI, and Tc99 bone scan uptake equal or superior to anterosuperior iliac crest. In our series, a tumor scoring 5 points or higher in the scale of aggressiveness can have 50% more chance of being LGC. When compared with the gold standard (the biopsy), surgeon's initial judgement showed a sensitivity of 73.5% and a specificity of 94.1%.

  • Enchondroma versus Chondrosarcoma in Long Bones of Appendicular Skeleton: Clinical and Radiological Criteria—A Follow-Up
    Journal of Oncology, 2016
    Co-Authors: Eugenio M. Ferrer-santacreu, Eduardo José Ortiz-cruz, Mariana Díaz-almirón, Jose Juan Pozo Kreilinger
    Abstract:

    As of today two types of cartilage tumors remain a challenge even for the Orthopedic Oncologist: enchondroma (E), a benign tumor, and chondrosarcoma (LGC), a malignant and low aggressiveness tumor. A prospective study of 133 patients with a cartilaginous tumor of low aggressiveness in the long bones of the appendicular skeleton was done to prove this difficult differential diagnosis. Parameters including medical history and radiological and nuclear imaging were collected and compared to the result of the biopsy. A scale of aggressiveness was applied to each patient according to the number of aggressiveness episodes present. A comparison of the results of the biopsy with the initial diagnosis made by the Orthopedic Oncologist based solely on clinical data and imaging tests was also made. Finally, a management algorithm for these cases was proposed. A statistical significance for LGC resulted from the parameter as follows: pain on palpation, involvement of cortical in either the CT or MRI, and Tc99 bone scan uptake equal or superior to anterosuperior iliac crest. In our series, a tumor scoring 5 points or higher in the scale of aggressiveness can have 50% more chance of being LGC. When compared with the gold standard (the biopsy), surgeon's initial judgement showed a sensitivity of 73.5% and a specificity of 94.1%.

Neal Chen - One of the best experts on this subject based on the ideXlab platform.

  • Proximal humerus allograft prosthetic composites: technique, outcomes, and pearls and pitfalls
    Current Reviews in Musculoskeletal Medicine, 2015
    Co-Authors: Santiago A. Lozano-calderón, Neal Chen
    Abstract:

    The proximal humerus is the second most common location of primary bone sarcomas and a frequent location of benign locally aggressive primary osseous tumors. In contrast to other locations, tumors in this region impose significant challenges for local control and reconstruction. This is due to glenohumeral joint anatomic characteristics such as lack of intrinsic stability and dependence on dynamic and static stabilizers. In addition, the close proximity of the axillary nerve and axillary vascular bundle places these at risk of resection when attaining local control. Allograft prosthetic composites (APCs) of the proximal humerus are one of the methods for mobile reconstruction. This modality presents lower fracture rates when compared to osteoarticular allografts and lower rates of subluxation and instability than endoprosthesis. Recent literature documents a trend for superior functional outcome at comparable complication rates. APC reconstruction is an important tool in the Orthopedic Oncologist armamentarium.

Eugenio M Ferrersantacreu - One of the best experts on this subject based on the ideXlab platform.

  • enchondroma versus chondrosarcoma in long bones of appendicular skeleton clinical and radiological criteria a follow up
    Journal of Oncology, 2016
    Co-Authors: Eugenio M Ferrersantacreu, Mariana Diazalmiron, Eduardo J Ortizcruz, Jose Juan Pozo Kreilinger
    Abstract:

    As of today two types of cartilage tumors remain a challenge even for the Orthopedic Oncologist: enchondroma (E), a benign tumor, and chondrosarcoma (LGC), a malignant and low aggressiveness tumor. A prospective study of 133 patients with a cartilaginous tumor of low aggressiveness in the long bones of the appendicular skeleton was done to prove this difficult differential diagnosis. Parameters including medical history and radiological and nuclear imaging were collected and compared to the result of the biopsy. A scale of aggressiveness was applied to each patient according to the number of aggressiveness episodes present. A comparison of the results of the biopsy with the initial diagnosis made by the Orthopedic Oncologist based solely on clinical data and imaging tests was also made. Finally, a management algorithm for these cases was proposed. A statistical significance for LGC resulted from the parameter as follows: pain on palpation, involvement of cortical in either the CT or MRI, and Tc99 bone scan uptake equal or superior to anterosuperior iliac crest. In our series, a tumor scoring 5 points or higher in the scale of aggressiveness can have 50% more chance of being LGC. When compared with the gold standard (the biopsy), surgeon's initial judgement showed a sensitivity of 73.5% and a specificity of 94.1%.

Santiago A. Lozano-calderón - One of the best experts on this subject based on the ideXlab platform.

  • Proximal humerus allograft prosthetic composites: technique, outcomes, and pearls and pitfalls
    Current Reviews in Musculoskeletal Medicine, 2015
    Co-Authors: Santiago A. Lozano-calderón, Neal Chen
    Abstract:

    The proximal humerus is the second most common location of primary bone sarcomas and a frequent location of benign locally aggressive primary osseous tumors. In contrast to other locations, tumors in this region impose significant challenges for local control and reconstruction. This is due to glenohumeral joint anatomic characteristics such as lack of intrinsic stability and dependence on dynamic and static stabilizers. In addition, the close proximity of the axillary nerve and axillary vascular bundle places these at risk of resection when attaining local control. Allograft prosthetic composites (APCs) of the proximal humerus are one of the methods for mobile reconstruction. This modality presents lower fracture rates when compared to osteoarticular allografts and lower rates of subluxation and instability than endoprosthesis. Recent literature documents a trend for superior functional outcome at comparable complication rates. APC reconstruction is an important tool in the Orthopedic Oncologist armamentarium.

German F. Farfalli - One of the best experts on this subject based on the ideXlab platform.

  • Techniques in surgical navigation of extremity tumors: state of the art
    Current Reviews in Musculoskeletal Medicine, 2015
    Co-Authors: Luis A. Aponte-tinao, Lucas E. Ritacco, Federico E. Milano, Miguel A. Ayerza, German F. Farfalli
    Abstract:

    Image-guided surgical navigation allows the Orthopedic Oncologist to perform adequate tumor resection based on fused images (CT, MRI, PET). Although surgical navigation was first performed in spine and pelvis, recent reports have described the use of this technique in bone tumors located in the extremities. In long bones, this technique has moved from localization or percutaneous resection of benign tumors to complex bone tumor resections and guided reconstructions (allograft or endoprostheses). In recent years, the reported series have increased from small numbers (5 to 16 patients) to larger ones (up to 130 patients). The purpose of this paper is to review recent reports regarding surgical navigation in the extremities, describing the results obtained with different kind of reconstructions when navigation is used and how the previously described problems were solved.