The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform

Carlos Blanche - One of the best experts on this subject based on the ideXlab platform.

  • Does total Orthotopic Heart Transplantation offer improved hemodynamics during cellular rejection events
    Transplantation proceedings, 2003
    Co-Authors: Ivan Aleksic, Carlos Blanche, Lawrence S.c. Czer, Dov Freimark, Alfredo Trento
    Abstract:

    Background We hypothesized that total Orthotopic Heart Transplantation (TOHT) improves hemodynamics during cellular rejection compared with biatrial Transplantation (SOHT).

  • Atrial emptying with Orthotopic Heart Transplantation using bicaval and pulmonary venous anastomoses: a magnetic resonance imaging study.
    Journal of the American College of Cardiology, 1995
    Co-Authors: Dov Freimark, Carlos Blanche, Alfredo Trento, Ivan Aleksic, Dan Admon, D. Harasty, Jeffrey M. Silverman, John V. Crues, Carmen A. Queral, Lawrence S.c. Czer
    Abstract:

    Objectives. We hypothesized that Orthotopic Heart Transplantation with bicaval and pulmonary venous anastomoses preserves atrial contractility. Background. The standard biatrial anastomotic technique of Orthotopic Heart Transplantation causes impaired function and enlargement of the atria. Cine magnetic resonance imaging (MRI) allows assessment of atrial size and function. Methods. We studied 16 patients who had undergone bicaval (n = 8) or biatrial (n = 8) Orthotopic Heart Transplantation without evidence of rejection and a control group of 6 healthy volunteers. For all three groups, cine MRI was performed by combining coronal and axial gated spin echo and gradient echo cine sequences. Intracardiac volumes were calculated with the Simpson rule. Atrial emptying fraction was defined as the difference between atrial diastolic and systolic volumes, divided by atrial diastolic volume, expressed in percent. All patients had right Heart catheterization. Results. Right atrial emptying fraction was significantly higher in the bicaval (mean [±SD] 37 ± 9%) than in the biatrial group (22 ± 11%, p Conclusions. Left and right atrial emptying fractions are significantly depressed with the biatrial technique and markedly improved with the bicaval technique of Orthotopic Heart Transplantation. The beneficial effects of the latter technique on atrial function could improve allograft exercise performance.

  • Alternative technique for Orthotopic Heart Transplantation
    The Annals of thoracic surgery, 1994
    Co-Authors: Carlos Blanche, Lawrence S.c. Czer, Mario Valenza, Alfredo Trento
    Abstract:

    An alternative technique for Orthotopic Heart Transplantation is described. The principle consists of total excision of the recipient's right atrium with donor Heart implantation performed using bicaval anastomoses; the left atrium is done in the standard fashion. This approach is technically simple and preserves the anatomic and physiologic function and integrity of the right atrium, especially the conduction system.

  • Orthotopic Heart Transplantation with bicaval and pulmonary venous anastomoses
    The Annals of thoracic surgery, 1994
    Co-Authors: Carlos Blanche, Lawrence S.c. Czer, Mario Valenza, Ivan Aleksic, Dov Freimark, Peter Barath, Dan Admon, D. Harasty, Caron Utley, Jack M. Matloff
    Abstract:

    We present our experience with an alternative technique for Orthotopic Heart Transplantation. It consists of total excision of the recipient's atria, with the donor's Heart implantation performed using bicaval end-to-end anastomoses as well as pulmonary venous anastomoses. Forty consecutive patients receiving transplants in this fashion were compared with 64 patients who underwent Orthotopic Transplantation with the standard technique. The incidence of postoperative tricuspid regurgitation was reduced in patients receiving transplants with the new surgical approach (p = 0.003). In addition, the need for pacemaker implantation for severe bradyarrhythmia in the early (0 to 6 weeks) postTransplantation period (p = 0.003) was eliminated. Although not statistically significant, there was a trend in the reduction of postoperative mitral regurgitation in patients who received transplants by the modified technique. Based on this experience, we believe this modified technique for Orthotopic Heart Transplantation has an anatomic and physiologic advantage that may improve long-term hemodynamic results.

Lawrence S.c. Czer - One of the best experts on this subject based on the ideXlab platform.

  • Does total Orthotopic Heart Transplantation offer improved hemodynamics during cellular rejection events
    Transplantation proceedings, 2003
    Co-Authors: Ivan Aleksic, Carlos Blanche, Lawrence S.c. Czer, Dov Freimark, Alfredo Trento
    Abstract:

    Background We hypothesized that total Orthotopic Heart Transplantation (TOHT) improves hemodynamics during cellular rejection compared with biatrial Transplantation (SOHT).

  • Atrial emptying with Orthotopic Heart Transplantation using bicaval and pulmonary venous anastomoses: a magnetic resonance imaging study.
    Journal of the American College of Cardiology, 1995
    Co-Authors: Dov Freimark, Carlos Blanche, Alfredo Trento, Ivan Aleksic, Dan Admon, D. Harasty, Jeffrey M. Silverman, John V. Crues, Carmen A. Queral, Lawrence S.c. Czer
    Abstract:

    Objectives. We hypothesized that Orthotopic Heart Transplantation with bicaval and pulmonary venous anastomoses preserves atrial contractility. Background. The standard biatrial anastomotic technique of Orthotopic Heart Transplantation causes impaired function and enlargement of the atria. Cine magnetic resonance imaging (MRI) allows assessment of atrial size and function. Methods. We studied 16 patients who had undergone bicaval (n = 8) or biatrial (n = 8) Orthotopic Heart Transplantation without evidence of rejection and a control group of 6 healthy volunteers. For all three groups, cine MRI was performed by combining coronal and axial gated spin echo and gradient echo cine sequences. Intracardiac volumes were calculated with the Simpson rule. Atrial emptying fraction was defined as the difference between atrial diastolic and systolic volumes, divided by atrial diastolic volume, expressed in percent. All patients had right Heart catheterization. Results. Right atrial emptying fraction was significantly higher in the bicaval (mean [±SD] 37 ± 9%) than in the biatrial group (22 ± 11%, p Conclusions. Left and right atrial emptying fractions are significantly depressed with the biatrial technique and markedly improved with the bicaval technique of Orthotopic Heart Transplantation. The beneficial effects of the latter technique on atrial function could improve allograft exercise performance.

  • Alternative technique for Orthotopic Heart Transplantation
    The Annals of thoracic surgery, 1994
    Co-Authors: Carlos Blanche, Lawrence S.c. Czer, Mario Valenza, Alfredo Trento
    Abstract:

    An alternative technique for Orthotopic Heart Transplantation is described. The principle consists of total excision of the recipient's right atrium with donor Heart implantation performed using bicaval anastomoses; the left atrium is done in the standard fashion. This approach is technically simple and preserves the anatomic and physiologic function and integrity of the right atrium, especially the conduction system.

  • Orthotopic Heart Transplantation with bicaval and pulmonary venous anastomoses
    The Annals of thoracic surgery, 1994
    Co-Authors: Carlos Blanche, Lawrence S.c. Czer, Mario Valenza, Ivan Aleksic, Dov Freimark, Peter Barath, Dan Admon, D. Harasty, Caron Utley, Jack M. Matloff
    Abstract:

    We present our experience with an alternative technique for Orthotopic Heart Transplantation. It consists of total excision of the recipient's atria, with the donor's Heart implantation performed using bicaval end-to-end anastomoses as well as pulmonary venous anastomoses. Forty consecutive patients receiving transplants in this fashion were compared with 64 patients who underwent Orthotopic Transplantation with the standard technique. The incidence of postoperative tricuspid regurgitation was reduced in patients receiving transplants with the new surgical approach (p = 0.003). In addition, the need for pacemaker implantation for severe bradyarrhythmia in the early (0 to 6 weeks) postTransplantation period (p = 0.003) was eliminated. Although not statistically significant, there was a trend in the reduction of postoperative mitral regurgitation in patients who received transplants by the modified technique. Based on this experience, we believe this modified technique for Orthotopic Heart Transplantation has an anatomic and physiologic advantage that may improve long-term hemodynamic results.

Alfredo Trento - One of the best experts on this subject based on the ideXlab platform.

  • Does total Orthotopic Heart Transplantation offer improved hemodynamics during cellular rejection events
    Transplantation proceedings, 2003
    Co-Authors: Ivan Aleksic, Carlos Blanche, Lawrence S.c. Czer, Dov Freimark, Alfredo Trento
    Abstract:

    Background We hypothesized that total Orthotopic Heart Transplantation (TOHT) improves hemodynamics during cellular rejection compared with biatrial Transplantation (SOHT).

  • Atrial emptying with Orthotopic Heart Transplantation using bicaval and pulmonary venous anastomoses: a magnetic resonance imaging study.
    Journal of the American College of Cardiology, 1995
    Co-Authors: Dov Freimark, Carlos Blanche, Alfredo Trento, Ivan Aleksic, Dan Admon, D. Harasty, Jeffrey M. Silverman, John V. Crues, Carmen A. Queral, Lawrence S.c. Czer
    Abstract:

    Objectives. We hypothesized that Orthotopic Heart Transplantation with bicaval and pulmonary venous anastomoses preserves atrial contractility. Background. The standard biatrial anastomotic technique of Orthotopic Heart Transplantation causes impaired function and enlargement of the atria. Cine magnetic resonance imaging (MRI) allows assessment of atrial size and function. Methods. We studied 16 patients who had undergone bicaval (n = 8) or biatrial (n = 8) Orthotopic Heart Transplantation without evidence of rejection and a control group of 6 healthy volunteers. For all three groups, cine MRI was performed by combining coronal and axial gated spin echo and gradient echo cine sequences. Intracardiac volumes were calculated with the Simpson rule. Atrial emptying fraction was defined as the difference between atrial diastolic and systolic volumes, divided by atrial diastolic volume, expressed in percent. All patients had right Heart catheterization. Results. Right atrial emptying fraction was significantly higher in the bicaval (mean [±SD] 37 ± 9%) than in the biatrial group (22 ± 11%, p Conclusions. Left and right atrial emptying fractions are significantly depressed with the biatrial technique and markedly improved with the bicaval technique of Orthotopic Heart Transplantation. The beneficial effects of the latter technique on atrial function could improve allograft exercise performance.

  • Alternative technique for Orthotopic Heart Transplantation
    The Annals of thoracic surgery, 1994
    Co-Authors: Carlos Blanche, Lawrence S.c. Czer, Mario Valenza, Alfredo Trento
    Abstract:

    An alternative technique for Orthotopic Heart Transplantation is described. The principle consists of total excision of the recipient's right atrium with donor Heart implantation performed using bicaval anastomoses; the left atrium is done in the standard fashion. This approach is technically simple and preserves the anatomic and physiologic function and integrity of the right atrium, especially the conduction system.

David D. Yuh - One of the best experts on this subject based on the ideXlab platform.

  • simple score to assess the risk of rejection after Orthotopic Heart Transplantation
    Circulation, 2012
    Co-Authors: Arman Kilic, Eric S. Weiss, Jeremiah G. Allen, John V. Conte, Ashish S. Shah, William A. Baumgartner, David D. Yuh
    Abstract:

    Background—The aim of this study was to derive and validate a risk score for rejection after Orthotopic Heart Transplantation. Methods and Results—The United Network for Organ Sharing registry was used to identify patients undergoing Orthotopic Heart Transplantation between 1998 and 2008. A total of 14 265 eligible patients were randomly divided into derivation (80%; n=11 412) and validation (20%; n=2853) cohorts. The primary outcome was drug-treated rejection within 1 year of Orthotopic Heart Transplantation. Covariates found to be associated (exploratory univariate P<0.2) with rejection were entered into a multivariable logistic regression model. Inclusion of each variable in the model was assessed by improvement in the McFadden pseudo-R2, likelihood ratio test, and c index. A risk score was then generated through the use of relative magnitudes of the odds ratios from the derivation cohort, and its ability to predict rejection was tested independently in the validation cohort. A 13-point risk score inco...

  • Simple Score to Assess the Risk of Rejection After Orthotopic Heart Transplantation
    Circulation, 2012
    Co-Authors: Arman Kilic, Eric S. Weiss, Jeremiah G. Allen, John V. Conte, Ashish S. Shah, William A. Baumgartner, David D. Yuh
    Abstract:

    Background—The aim of this study was to derive and validate a risk score for rejection after Orthotopic Heart Transplantation. Methods and Results—The United Network for Organ Sharing registry was used to identify patients undergoing Orthotopic Heart Transplantation between 1998 and 2008. A total of 14 265 eligible patients were randomly divided into derivation (80%; n=11 412) and validation (20%; n=2853) cohorts. The primary outcome was drug-treated rejection within 1 year of Orthotopic Heart Transplantation. Covariates found to be associated (exploratory univariate P

José M. Padró - One of the best experts on this subject based on the ideXlab platform.