The Experts below are selected from a list of 1290 Experts worldwide ranked by ideXlab platform
Lei Liu - One of the best experts on this subject based on the ideXlab platform.
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A Comparison of Triamcinolone Acetonide Econazole Cream and Nystatin Suspension in Treatment of Otomycosis.
The Laryngoscope, 2020Co-Authors: Qingguo Chen, Hanqi Chu, Yanling Tao, Liyan Peng, Liangqiang Zhou, Lei LiuAbstract:OBJECTIVES/HYPOTHESIS To compare the efficacy and adverse effects of triamcinolone acetonide econazole cream and nystatin suspension in the treatment of Otomycosis, and to determine the clinical features, predisposing factors, and etiology of Otomycosis. STUDY DESIGN A prospective study. METHODS A prospective clinical trial was conducted on 786 patients diagnosed with Otomycosis. The study population was randomly divided into two treatment groups of triamcinolone acetonide econazole cream (TAEC) and nystatin suspension in a 1:1 ratio. After clearing all fungal deposits in the external auditory canal, the antimycotic drugs were locally applied for at least 2 weeks. The efficacy and adverse effects were compared between the two antifungal reagents by statistical analysis. Meanwhile, patient clinical data were collected to find out the clinical features, predisposing factors, and etiology. RESULTS Pruritis was the most common symptom and Aspergillus niger was the leading fungal pathogen. There was high association (44.5%) of Otomycosis with a history of unclean ear picking. The cure rate was 97.6% in the TAEC group and 73.5% in the nystatin group (P
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a comparison of triamcinolone acetonide econazole cream and nystatin suspension in treatment of Otomycosis
Laryngoscope, 2020Co-Authors: Qingguo Chen, Hanqi Chu, Yanling Tao, Liyan Peng, Liangqiang Zhou, Lei LiuAbstract:OBJECTIVES/HYPOTHESIS To compare the efficacy and adverse effects of triamcinolone acetonide econazole cream and nystatin suspension in the treatment of Otomycosis, and to determine the clinical features, predisposing factors, and etiology of Otomycosis. STUDY DESIGN A prospective study. METHODS A prospective clinical trial was conducted on 786 patients diagnosed with Otomycosis. The study population was randomly divided into two treatment groups of triamcinolone acetonide econazole cream (TAEC) and nystatin suspension in a 1:1 ratio. After clearing all fungal deposits in the external auditory canal, the antimycotic drugs were locally applied for at least 2 weeks. The efficacy and adverse effects were compared between the two antifungal reagents by statistical analysis. Meanwhile, patient clinical data were collected to find out the clinical features, predisposing factors, and etiology. RESULTS Pruritis was the most common symptom and Aspergillus niger was the leading fungal pathogen. There was high association (44.5%) of Otomycosis with a history of unclean ear picking. The cure rate was 97.6% in the TAEC group and 73.5% in the nystatin group (P < .01). Treatment with TAEC resulted in 2.4% of patients complaining of discomforts (irritant dermatitis, otalgia, or headache) versus 59.8% of patients complaining discomforts treated with nystatin (P < .01). The residue rate of antifungals was 1.9% in the TAEC group and 89.9% in the nystatin group (P < .01) at the end of treatment. CONCLUSIONS Thoroughly cleaning of the external auditory canal followed by local use of TAEC under endotoscope is an effective, convenient, and well-tolerated treatment for Otomycosis. LEVEL OF EVIDENCE 1 Laryngoscope, 2020.
Qingguo Chen - One of the best experts on this subject based on the ideXlab platform.
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A Comparison of Triamcinolone Acetonide Econazole Cream and Nystatin Suspension in Treatment of Otomycosis.
The Laryngoscope, 2020Co-Authors: Qingguo Chen, Hanqi Chu, Yanling Tao, Liyan Peng, Liangqiang Zhou, Lei LiuAbstract:OBJECTIVES/HYPOTHESIS To compare the efficacy and adverse effects of triamcinolone acetonide econazole cream and nystatin suspension in the treatment of Otomycosis, and to determine the clinical features, predisposing factors, and etiology of Otomycosis. STUDY DESIGN A prospective study. METHODS A prospective clinical trial was conducted on 786 patients diagnosed with Otomycosis. The study population was randomly divided into two treatment groups of triamcinolone acetonide econazole cream (TAEC) and nystatin suspension in a 1:1 ratio. After clearing all fungal deposits in the external auditory canal, the antimycotic drugs were locally applied for at least 2 weeks. The efficacy and adverse effects were compared between the two antifungal reagents by statistical analysis. Meanwhile, patient clinical data were collected to find out the clinical features, predisposing factors, and etiology. RESULTS Pruritis was the most common symptom and Aspergillus niger was the leading fungal pathogen. There was high association (44.5%) of Otomycosis with a history of unclean ear picking. The cure rate was 97.6% in the TAEC group and 73.5% in the nystatin group (P
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a comparison of triamcinolone acetonide econazole cream and nystatin suspension in treatment of Otomycosis
Laryngoscope, 2020Co-Authors: Qingguo Chen, Hanqi Chu, Yanling Tao, Liyan Peng, Liangqiang Zhou, Lei LiuAbstract:OBJECTIVES/HYPOTHESIS To compare the efficacy and adverse effects of triamcinolone acetonide econazole cream and nystatin suspension in the treatment of Otomycosis, and to determine the clinical features, predisposing factors, and etiology of Otomycosis. STUDY DESIGN A prospective study. METHODS A prospective clinical trial was conducted on 786 patients diagnosed with Otomycosis. The study population was randomly divided into two treatment groups of triamcinolone acetonide econazole cream (TAEC) and nystatin suspension in a 1:1 ratio. After clearing all fungal deposits in the external auditory canal, the antimycotic drugs were locally applied for at least 2 weeks. The efficacy and adverse effects were compared between the two antifungal reagents by statistical analysis. Meanwhile, patient clinical data were collected to find out the clinical features, predisposing factors, and etiology. RESULTS Pruritis was the most common symptom and Aspergillus niger was the leading fungal pathogen. There was high association (44.5%) of Otomycosis with a history of unclean ear picking. The cure rate was 97.6% in the TAEC group and 73.5% in the nystatin group (P < .01). Treatment with TAEC resulted in 2.4% of patients complaining of discomforts (irritant dermatitis, otalgia, or headache) versus 59.8% of patients complaining discomforts treated with nystatin (P < .01). The residue rate of antifungals was 1.9% in the TAEC group and 89.9% in the nystatin group (P < .01) at the end of treatment. CONCLUSIONS Thoroughly cleaning of the external auditory canal followed by local use of TAEC under endotoscope is an effective, convenient, and well-tolerated treatment for Otomycosis. LEVEL OF EVIDENCE 1 Laryngoscope, 2020.
Gholamabbas Sabz - One of the best experts on this subject based on the ideXlab platform.
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Clinical and microbial epidemiology of Otomycosis in the city of Yasuj, southwest Iran, revealing Aspergillus tubingensis as the dominant causative agent.
Journal of medical microbiology, 2019Co-Authors: Gholamabbas Sabz, Maral Gharaghani, Hossein Mirhendi, Bahram Ahmadi, Mohamad Amin Gatee, Marzie Taheripour Sisakht, Alireza Hemati, Reza Mohammadi, Jabar Taghavi, Sadegh Nouripour-sisakhtAbstract:Otomycosis is a mycotic infection of the external auditory canal and can be caused by a wide range of fungal species. In this study, we aimed to identify fungal isolates from patients suspected of Otomycosis. External ear canal samples were taken from patients referred to the outpatient department of Shahid-Mofatteh Clinic in the city of Yasuj, Iran, and examined by direct microscopy and culture. DNA of the isolated fungi was tested by internal transcribed spacer PCR restriction fragment length polymorphism analysis for identification of yeasts and β-tubulin sequencing for identification of Aspergillus species. Among 275 patients suspected of Otomycosis, 144 cases (83 female and 61 male) were confirmed with Otomycosis. For 89% (n=128) of positive cultures, microscopy was also positive, while there were no cases with a microscopy-positive and culture-negative result. The predominant predisposing factor was self-cleaning of the external ear using unhygienic tools, and the main risk occupation was 'housewife'. The most common isolated fungi were typically Aspergillus (n=120), including 73 isolates of Aspergillus section Nigri, 43 of section Flavi, 3 of section Terrei and 1 of section Fumigati. After sequencing, 44 out of 73 strains primarily identified as Aspergillus niger turned out to be Aspergillus tubingensis. Thirty-five isolates were identified as Candida, including Candida parapsilosis (n=22), Candida albicans (n=12) and Candida tropicalis (n=1). Aspergillus tubingensis was the most common species involved in Otomycosis. This work corroborates the difficulty of precise identification of species within the black Aspergilli by morphological characteristics.
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clinical and microbial epidemiology of Otomycosis in the city of yasuj southwest iran revealing aspergillus tubingensis as the dominant causative agent
Journal of Medical Microbiology, 2019Co-Authors: Gholamabbas Sabz, Maral Gharaghani, Hossein Mirhendi, Bahram Ahmadi, Mohamad Amin Gatee, Marzie Taheripour Sisakht, Alireza Hemati, Reza Mohammadi, Jabar Taghavi, Sadegh NouripoursisakhtAbstract:Purpose Otomycosis is a mycotic infection of the external auditory canal and can be caused by a wide range of fungal species. In this study, we aimed to identify fungal isolates from patients suspected of Otomycosis. Methodology External ear canal samples were taken from patients referred to the outpatient department of Shahid-Mofatteh Clinic in the city of Yasuj, Iran, and examined by direct microscopy and culture. DNA of the isolated fungi was tested by internal transcribed spacer PCR restriction fragment length polymorphism analysis for identification of yeasts and β-tubulin sequencing for identification of Aspergillus species. Results Among 275 patients suspected of Otomycosis, 144 cases (83 female and 61 male) were confirmed with Otomycosis. For 89% (n=128) of positive cultures, microscopy was also positive, while there were no cases with a microscopy-positive and culture-negative result. The predominant predisposing factor was self-cleaning of the external ear using unhygienic tools, and the main risk occupation was 'housewife'. The most common isolated fungi were typically Aspergillus (n=120), including 73 isolates of Aspergillus section Nigri, 43 of section Flavi, 3 of section Terrei and 1 of section Fumigati. After sequencing, 44 out of 73 strains primarily identified as Aspergillus niger turned out to be Aspergillus tubingensis. Thirty-five isolates were identified as Candida, including Candida parapsilosis (n=22), Candida albicans (n=12) and Candida tropicalis (n=1). Conclusion Aspergillus tubingensis was the most common species involved in Otomycosis. This work corroborates the difficulty of precise identification of species within the black Aspergilli by morphological characteristics.
Sadegh Nouripour-sisakht - One of the best experts on this subject based on the ideXlab platform.
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Clinical and microbial epidemiology of Otomycosis in the city of Yasuj, southwest Iran, revealing Aspergillus tubingensis as the dominant causative agent.
Journal of medical microbiology, 2019Co-Authors: Gholamabbas Sabz, Maral Gharaghani, Hossein Mirhendi, Bahram Ahmadi, Mohamad Amin Gatee, Marzie Taheripour Sisakht, Alireza Hemati, Reza Mohammadi, Jabar Taghavi, Sadegh Nouripour-sisakhtAbstract:Otomycosis is a mycotic infection of the external auditory canal and can be caused by a wide range of fungal species. In this study, we aimed to identify fungal isolates from patients suspected of Otomycosis. External ear canal samples were taken from patients referred to the outpatient department of Shahid-Mofatteh Clinic in the city of Yasuj, Iran, and examined by direct microscopy and culture. DNA of the isolated fungi was tested by internal transcribed spacer PCR restriction fragment length polymorphism analysis for identification of yeasts and β-tubulin sequencing for identification of Aspergillus species. Among 275 patients suspected of Otomycosis, 144 cases (83 female and 61 male) were confirmed with Otomycosis. For 89% (n=128) of positive cultures, microscopy was also positive, while there were no cases with a microscopy-positive and culture-negative result. The predominant predisposing factor was self-cleaning of the external ear using unhygienic tools, and the main risk occupation was 'housewife'. The most common isolated fungi were typically Aspergillus (n=120), including 73 isolates of Aspergillus section Nigri, 43 of section Flavi, 3 of section Terrei and 1 of section Fumigati. After sequencing, 44 out of 73 strains primarily identified as Aspergillus niger turned out to be Aspergillus tubingensis. Thirty-five isolates were identified as Candida, including Candida parapsilosis (n=22), Candida albicans (n=12) and Candida tropicalis (n=1). Aspergillus tubingensis was the most common species involved in Otomycosis. This work corroborates the difficulty of precise identification of species within the black Aspergilli by morphological characteristics.
Sadegh Nouripoursisakht - One of the best experts on this subject based on the ideXlab platform.
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clinical and microbial epidemiology of Otomycosis in the city of yasuj southwest iran revealing aspergillus tubingensis as the dominant causative agent
Journal of Medical Microbiology, 2019Co-Authors: Gholamabbas Sabz, Maral Gharaghani, Hossein Mirhendi, Bahram Ahmadi, Mohamad Amin Gatee, Marzie Taheripour Sisakht, Alireza Hemati, Reza Mohammadi, Jabar Taghavi, Sadegh NouripoursisakhtAbstract:Purpose Otomycosis is a mycotic infection of the external auditory canal and can be caused by a wide range of fungal species. In this study, we aimed to identify fungal isolates from patients suspected of Otomycosis. Methodology External ear canal samples were taken from patients referred to the outpatient department of Shahid-Mofatteh Clinic in the city of Yasuj, Iran, and examined by direct microscopy and culture. DNA of the isolated fungi was tested by internal transcribed spacer PCR restriction fragment length polymorphism analysis for identification of yeasts and β-tubulin sequencing for identification of Aspergillus species. Results Among 275 patients suspected of Otomycosis, 144 cases (83 female and 61 male) were confirmed with Otomycosis. For 89% (n=128) of positive cultures, microscopy was also positive, while there were no cases with a microscopy-positive and culture-negative result. The predominant predisposing factor was self-cleaning of the external ear using unhygienic tools, and the main risk occupation was 'housewife'. The most common isolated fungi were typically Aspergillus (n=120), including 73 isolates of Aspergillus section Nigri, 43 of section Flavi, 3 of section Terrei and 1 of section Fumigati. After sequencing, 44 out of 73 strains primarily identified as Aspergillus niger turned out to be Aspergillus tubingensis. Thirty-five isolates were identified as Candida, including Candida parapsilosis (n=22), Candida albicans (n=12) and Candida tropicalis (n=1). Conclusion Aspergillus tubingensis was the most common species involved in Otomycosis. This work corroborates the difficulty of precise identification of species within the black Aspergilli by morphological characteristics.
