Overlap Syndrome

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Vincenzo Baldo - One of the best experts on this subject based on the ideXlab platform.

Paolo Muratori - One of the best experts on this subject based on the ideXlab platform.

A Floreani - One of the best experts on this subject based on the ideXlab platform.

Barbara Phillips - One of the best experts on this subject based on the ideXlab platform.

  • New developments in the management of chronic obstructive pulmonary disease and the Overlap Syndrome.
    Current treatment options in neurology, 2011
    Co-Authors: Adam Kouns, Barbara Phillips
    Abstract:

    The “Overlap Syndrome” is the concurrence of chronic obstructive pulmonary disease (COPD) with obstructive sleep apnea (OSA). This condition is not particularly well defined, and there is a paucity of data about the effects of any specific treatment on its outcomes. Until now, optimum treatment of the Overlap Syndrome could probably be best described as optimum treatment of each of its components, and there was no specific reason to think that treating one part of the Syndrome would ameliorate the other part. However, recent observational data have demonstrated improved survival and reduced exacerbations in patients with the Overlap Syndrome who are treated with continuous positive airway pressure (CPAP). Physicians caring for patients with COPD should screen for OSA and have a low threshold for initiating CPAP treatment in those COPD patients who are found to have OSA.

  • The Overlap Syndrome: chronic obstructive pulmonary disease and obstructive sleep apnea.
    Critical care clinics, 2008
    Co-Authors: David M. Hiestand, Barbara Phillips
    Abstract:

    The Overlap Syndrome defines the relationship between obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), and is a commonly noted but poorly studied disorder. Individuals who have the Overlap Syndrome have been recognized to have greater risk for pulmonary hypertension, right heart failure, and hypercapnia than patients who have either disorder alone. In patients who have advanced-stage COPD, concomitant OSA likely has significant adverse consequences. The interaction between these two diseases is unclear, however. Further clinical trials of the Overlap Syndrome are urgently needed.

Marina G. Silveira - One of the best experts on this subject based on the ideXlab platform.