The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Satoshi Minakata - One of the best experts on this subject based on the ideXlab platform.
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Oxidative Dimerization of hetero aromatic amines utilizing t buoi leading to hetero aromatic azo compounds scope and mechanistic studies
Journal of Organic Chemistry, 2013Co-Authors: Sota Okumura, Youhei Takeda, Chunhsuan Lin, Satoshi MinakataAbstract:A straightforward synthetic method of both symmetric and unsymmetric aromatic azo compounds through an efficient and cross-selective Oxidative Dimerization of aromatic amines using tert-butyl hypoiodite (t-BuOI) under metal-free and mild conditions has been developed. This method was also found applicable to the synthesis of heteroaromatic azo compounds. The spectroscopic study indicates the involvement of N,N-diiodoanilines in the Oxidative reaction as the key intermediate.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A convenient method with an excess of tBuOCl and NaI is developed to give various symmetrical azobenzenes in good yields.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
Synthesis, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A straightforward, convenient, and efficient synthetic method of azobenzenes through Oxidative Dimerization of aromatic amines using a unique and cost-effective iodinating reagent is described. This new method allows for easy access to both of symmetrical and unsymmetrical azobenzenes under extremely mild conditions.
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Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:Homo- and cross-Dimerization of the aromatic and heteroaromatic amines is achieved using tBuOI, generated in situ, to afford symmetric and unsymmetric aromatic azo compounds in good yields.
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Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
Angewandte Chemie, 2012Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:It's all the hype: An Oxidative Dimerization reaction of aromatic amines utilizing tert-butyl hypoiodite (tBuOI) under mild reaction conditions leads to aromatic azo compounds. The method allows access to unsymmetric aromatic azo compounds, which are difficult to prepare by conventional synthetic methods, in a selective manner.
Youhei Takeda - One of the best experts on this subject based on the ideXlab platform.
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Oxidative Dimerization of hetero aromatic amines utilizing t buoi leading to hetero aromatic azo compounds scope and mechanistic studies
Journal of Organic Chemistry, 2013Co-Authors: Sota Okumura, Youhei Takeda, Chunhsuan Lin, Satoshi MinakataAbstract:A straightforward synthetic method of both symmetric and unsymmetric aromatic azo compounds through an efficient and cross-selective Oxidative Dimerization of aromatic amines using tert-butyl hypoiodite (t-BuOI) under metal-free and mild conditions has been developed. This method was also found applicable to the synthesis of heteroaromatic azo compounds. The spectroscopic study indicates the involvement of N,N-diiodoanilines in the Oxidative reaction as the key intermediate.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A convenient method with an excess of tBuOCl and NaI is developed to give various symmetrical azobenzenes in good yields.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
Synthesis, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A straightforward, convenient, and efficient synthetic method of azobenzenes through Oxidative Dimerization of aromatic amines using a unique and cost-effective iodinating reagent is described. This new method allows for easy access to both of symmetrical and unsymmetrical azobenzenes under extremely mild conditions.
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Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:Homo- and cross-Dimerization of the aromatic and heteroaromatic amines is achieved using tBuOI, generated in situ, to afford symmetric and unsymmetric aromatic azo compounds in good yields.
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Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
Angewandte Chemie, 2012Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:It's all the hype: An Oxidative Dimerization reaction of aromatic amines utilizing tert-butyl hypoiodite (tBuOI) under mild reaction conditions leads to aromatic azo compounds. The method allows access to unsymmetric aromatic azo compounds, which are difficult to prepare by conventional synthetic methods, in a selective manner.
Sota Okumura - One of the best experts on this subject based on the ideXlab platform.
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Oxidative Dimerization of hetero aromatic amines utilizing t buoi leading to hetero aromatic azo compounds scope and mechanistic studies
Journal of Organic Chemistry, 2013Co-Authors: Sota Okumura, Youhei Takeda, Chunhsuan Lin, Satoshi MinakataAbstract:A straightforward synthetic method of both symmetric and unsymmetric aromatic azo compounds through an efficient and cross-selective Oxidative Dimerization of aromatic amines using tert-butyl hypoiodite (t-BuOI) under metal-free and mild conditions has been developed. This method was also found applicable to the synthesis of heteroaromatic azo compounds. The spectroscopic study indicates the involvement of N,N-diiodoanilines in the Oxidative reaction as the key intermediate.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A convenient method with an excess of tBuOCl and NaI is developed to give various symmetrical azobenzenes in good yields.
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a practical synthesis of azobenzenes through Oxidative Dimerization of aromatic amines using tert butyl hypoiodite
Synthesis, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:A straightforward, convenient, and efficient synthetic method of azobenzenes through Oxidative Dimerization of aromatic amines using a unique and cost-effective iodinating reagent is described. This new method allows for easy access to both of symmetrical and unsymmetrical azobenzenes under extremely mild conditions.
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Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
ChemInform, 2013Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:Homo- and cross-Dimerization of the aromatic and heteroaromatic amines is achieved using tBuOI, generated in situ, to afford symmetric and unsymmetric aromatic azo compounds in good yields.
-
Oxidative Dimerization of aromatic amines using tbuoi entry to unsymmetric aromatic azo compounds
Angewandte Chemie, 2012Co-Authors: Youhei Takeda, Sota Okumura, Satoshi MinakataAbstract:It's all the hype: An Oxidative Dimerization reaction of aromatic amines utilizing tert-butyl hypoiodite (tBuOI) under mild reaction conditions leads to aromatic azo compounds. The method allows access to unsymmetric aromatic azo compounds, which are difficult to prepare by conventional synthetic methods, in a selective manner.
Tsutomu Nakayama - One of the best experts on this subject based on the ideXlab platform.
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efficient synthesis of theaflavin 3 gallate by a tyrosinase catalyzed reaction with epicatechin and epigallocatechin gallate in a 1 octanol buffer biphasic system
Journal of Agricultural and Food Chemistry, 2018Co-Authors: Asako Naraikanayama, Yoshinori Uekusa, Fumiyuki Kiuchi, Tsutomu NakayamaAbstract:Theaflavins, the orange-red pigments contained in black tea, have attracted attention as a result of their health-promoting effects. However, their synthetic preparation, in which the enzymatic oxidation of catechol-type catechin is followed by the quinone-induced Oxidative Dimerization of selectively combined catechol- and pyrogallol-type catechins, provides only a low yield. In the present study, we found that a 1-octanol/buffer biphasic system improved the yield of theaflavin 3-gallate in a tyrosinase-catalyzed synthetic reaction with (-)-epicatechin and (-)-epigallocatechin gallate. When the enzymatic reaction proceeded in a buffer solution, oxidized (-)-epigallocatechin gallate was preferentially used for self-Dimerization. However, self-Dimerization was suppressed in the octanol phase, allowing oxidized (-)-epigallocatechin gallate to participate in coupling with (-)-epicatechin quinone, leading to effective production of theaflavin 3-gallate. Furthermore, the preferential localization of theaflavin 3-gallate in the octanol phase prevented (-)-epicatechin-quinone-induced degradation.
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Efficient Synthesis of Theaflavin 3‑Gallate by a Tyrosinase-Catalyzed Reaction with (−)-Epicatechin and (−)-Epigallocatechin Gallate in a 1‑Octanol/Buffer Biphasic System
2018Co-Authors: Asako Narai-kanayama, Yoshinori Uekusa, Fumiyuki Kiuchi, Tsutomu NakayamaAbstract:Theaflavins, the orange–red pigments contained in black tea, have attracted attention as a result of their health-promoting effects. However, their synthetic preparation, in which the enzymatic oxidation of catechol-type catechin is followed by the quinone-induced Oxidative Dimerization of selectively combined catechol- and pyrogallol-type catechins, provides only a low yield. In the present study, we found that a 1-octanol/buffer biphasic system improved the yield of theaflavin 3-gallate in a tyrosinase-catalyzed synthetic reaction with (−)-epicatechin and (−)-epigallocatechin gallate. When the enzymatic reaction proceeded in a buffer solution, oxidized (−)-epigallocatechin gallate was preferentially used for self-Dimerization. However, self-Dimerization was suppressed in the octanol phase, allowing oxidized (−)-epigallocatechin gallate to participate in coupling with (−)-epicatechin quinone, leading to effective production of theaflavin 3-gallate. Furthermore, the preferential localization of theaflavin 3-gallate in the octanol phase prevented (−)-epicatechin-quinone-induced degradation
Yuming Zhao - One of the best experts on this subject based on the ideXlab platform.
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bromophenyl substituted dithiafulvenes and tetrathiafulvalene vinylogues synthesis structure and electronic properties
ChemInform, 2013Co-Authors: Stephen Bouzan, Louise N Dawe, Yuming ZhaoAbstract:Oxidative Dimerization of readily prepared bromophenyl substituted dithiafulvalenes (IIIa,b) offers a convenient synthesis of bis(bromophenyl) substituted tetrathiafulvalene vinylogues.
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bromophenyl substituted dithiafulvenes and tetrathiafulvalene vinylogues synthesis structure and electronic properties
Tetrahedron Letters, 2013Co-Authors: Stephen Bouzan, Louise N Dawe, Yuming ZhaoAbstract:Abstract Bis(bromophenyl) substituted tetrathiafulvalene vinylogues (TTFVs) were prepared via Oxidative Dimerization reactions of corresponding bromophenyl substituted dithiafulvene precursors. The synthesis of ortho -bromophenyl TTFVs led to the formation of an unexpected bis-spiro product, the structure of which was clearly elucidated by single crystal X-ray crystallography. Electronic and redox properties of the bromophenyl substituted dithiafulvenes, TTFV derivatives, and the related bis-spiro compound were investigated by UV–vis spectroscopic and cyclic voltammetric analyses. Detailed structure–property relationships have been discussed.
