The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
P Wouters - One of the best experts on this subject based on the ideXlab platform.
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A prototype device for standardized calibration of pulse Oximeters II.
Journal of clinical monitoring and computing, 2002Co-Authors: Ch Hornberger, Ph Knoop, H Matz, F Dörries, E Konecny, H Gehring, J Otten, R Bonk, H Frankenberger, P WoutersAbstract:There is no commonly accepted in vivo calibration method for pulse Oximeters available up to now. On the basis of a prototype device for the calibration of pulse Oximeters which was introduced recently, a second approach based on the same concept was tackled in order to design a reliable method for standardized calibration of pulse Oximeters. An extensive clinical database of time-resolved optical transmission spectra of patient fingers is used to simulate the behavior of patients. A device which is capable of playing back these spectroscopic data to pulse Oximeters, and a database where the oxygen status measured with the reference method (Co-Oximetry) is stored, are the main parts of the concept. The playback device has an artificial finger as interface to the pulse Oximeters and serves to collect light from the pulse Oximeter for analysis and to playback simulated light to the pulse Oximeter. The light intensity emitted by two LEDs which illuminates the pulse Oximeter detector is controlled via a computer in such a way that it is the same as if the pulse Oximeter light had passed the finger. The pulse Oximeter display during the data playback can thus be compared to the true SaO2 of the patient. The device is tested with 4 pulse Oximeters based on 100 patient spectra. For the four pulse Oximeters used in this investigation, an Agilent Technologies CMS monitor (formerly Hewlett-Packard), an Ivy 2000 with Masimo Set technology and Nellcor N-3000 and N-395, there is good correlation between SPO2 and SaO2, and mean and standard deviation of in vivo SpO2-SaO2 and playback SpO2-SaO2 are in good agreement. For two instruments, Nellcor N3000 and Agilent CMS Monitor, a quantitative comparison between the in vivo and in vitro SpO, results was derived. A mean of the deviation playback vs. in vivo SpO2 is less than 0.5% SpO2. The error limits are comparable with the calibration error of the conventional calibration routine. The device is also capable of data playback even in situations with rapid desaturation changes, as displayed in Figure 2. For the other tested pulse Oximeters the results are comparable. Compared to the first prototype the current version is simpler and less expensive in production. Many of previously existing problems are solved and the applicability to a large variety of pulse Oximeters and sensors is given. The novel concept for the calibration of pulse Oximeters is a tool for assessing the performance of pulse Oximeters.
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A prototype device for standardized calibration of pulse Oximeters.
Journal of clinical monitoring and computing, 2000Co-Authors: Ch Hornberger, Ph Knoop, H Matz, E Konecny, H Gehring, R Bonk, H Frankenberger, Werner Nahm, Geert Meyfroidt, P WoutersAbstract:Objective.To develop and test a method for standardized calibrationof pulse Oximeters. Methods.A novel pulse Oximeter calibrationtechnique capable of simulating the behavior of real patients is discussed.It is based on an artificial finger with a variable spectral-resolved lightattenuator in conjunction with an extensive clinical database of time-resolvedoptical transmission spectra of patients fingers in the wavelength range600–1000 nm. The arterial oxygen saturation of the patients at the timeof recording was derived by analyzing a corresponding blood sample with aCO-Oximeter. These spectra are used to compute the modulation of the lightattenuator which is attached to the artificial finger. This calibration methodwas tested by arbitrarily playing back recorded spectra to pulse Oximeters andcomparing their display to the value they displayed when the spectra wererecorded. Results.We were able to demonstrate that the calibratorcould generate physiological signals which are accepted by a pulse Oximeter.We also present some experience of playing back recorded patient spectra. Themean difference between the original reading of the pulse Oximeters and thedisplay when attached to the calibrator is 1.2 saturation points (displayedoxygen saturation SpO2) with a standard deviation of 1.9 saturationpoints. Conclusions.The tests have shown the capabilities of aspectral light modulator for use as a possible calibration standard for pulseOximeters. If some improvements of the current prototype can be achieved weconclude from the experience with the device that this novel concept for thecalibration of pulse Oximeters is feasible and that it could become animportant tool for assessing the performance of pulse Oximeters.
Ben Stenson - One of the best experts on this subject based on the ideXlab platform.
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
Peter Brocklehurst - One of the best experts on this subject based on the ideXlab platform.
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pulse Oximeter saturation targeting and Oximeter changes in the benefits of oxygen saturation targeting boost ii australia and boost ii uk oxygen trials
The Journal of Pediatrics, 2019Co-Authors: B Stenson, Peter Brocklehurst, Mark Donoghoe, Peter G Davis, Edmund Juszczak, Ian C Marschner, John Simes, William TarnowmordiAbstract:Infants in the Australian and UK Benefits of Oxygen Saturation Targeting-II trials treated using revised Oximeters spent more time within their planned pulse Oximeter saturation target ranges than infants treated using the original Oximeters (P
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
Ch Hornberger - One of the best experts on this subject based on the ideXlab platform.
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A prototype device for standardized calibration of pulse Oximeters II.
Journal of clinical monitoring and computing, 2002Co-Authors: Ch Hornberger, Ph Knoop, H Matz, F Dörries, E Konecny, H Gehring, J Otten, R Bonk, H Frankenberger, P WoutersAbstract:There is no commonly accepted in vivo calibration method for pulse Oximeters available up to now. On the basis of a prototype device for the calibration of pulse Oximeters which was introduced recently, a second approach based on the same concept was tackled in order to design a reliable method for standardized calibration of pulse Oximeters. An extensive clinical database of time-resolved optical transmission spectra of patient fingers is used to simulate the behavior of patients. A device which is capable of playing back these spectroscopic data to pulse Oximeters, and a database where the oxygen status measured with the reference method (Co-Oximetry) is stored, are the main parts of the concept. The playback device has an artificial finger as interface to the pulse Oximeters and serves to collect light from the pulse Oximeter for analysis and to playback simulated light to the pulse Oximeter. The light intensity emitted by two LEDs which illuminates the pulse Oximeter detector is controlled via a computer in such a way that it is the same as if the pulse Oximeter light had passed the finger. The pulse Oximeter display during the data playback can thus be compared to the true SaO2 of the patient. The device is tested with 4 pulse Oximeters based on 100 patient spectra. For the four pulse Oximeters used in this investigation, an Agilent Technologies CMS monitor (formerly Hewlett-Packard), an Ivy 2000 with Masimo Set technology and Nellcor N-3000 and N-395, there is good correlation between SPO2 and SaO2, and mean and standard deviation of in vivo SpO2-SaO2 and playback SpO2-SaO2 are in good agreement. For two instruments, Nellcor N3000 and Agilent CMS Monitor, a quantitative comparison between the in vivo and in vitro SpO, results was derived. A mean of the deviation playback vs. in vivo SpO2 is less than 0.5% SpO2. The error limits are comparable with the calibration error of the conventional calibration routine. The device is also capable of data playback even in situations with rapid desaturation changes, as displayed in Figure 2. For the other tested pulse Oximeters the results are comparable. Compared to the first prototype the current version is simpler and less expensive in production. Many of previously existing problems are solved and the applicability to a large variety of pulse Oximeters and sensors is given. The novel concept for the calibration of pulse Oximeters is a tool for assessing the performance of pulse Oximeters.
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A prototype device for standardized calibration of pulse Oximeters.
Journal of clinical monitoring and computing, 2000Co-Authors: Ch Hornberger, Ph Knoop, H Matz, E Konecny, H Gehring, R Bonk, H Frankenberger, Werner Nahm, Geert Meyfroidt, P WoutersAbstract:Objective.To develop and test a method for standardized calibrationof pulse Oximeters. Methods.A novel pulse Oximeter calibrationtechnique capable of simulating the behavior of real patients is discussed.It is based on an artificial finger with a variable spectral-resolved lightattenuator in conjunction with an extensive clinical database of time-resolvedoptical transmission spectra of patients fingers in the wavelength range600–1000 nm. The arterial oxygen saturation of the patients at the timeof recording was derived by analyzing a corresponding blood sample with aCO-Oximeter. These spectra are used to compute the modulation of the lightattenuator which is attached to the artificial finger. This calibration methodwas tested by arbitrarily playing back recorded spectra to pulse Oximeters andcomparing their display to the value they displayed when the spectra wererecorded. Results.We were able to demonstrate that the calibratorcould generate physiological signals which are accepted by a pulse Oximeter.We also present some experience of playing back recorded patient spectra. Themean difference between the original reading of the pulse Oximeters and thedisplay when attached to the calibrator is 1.2 saturation points (displayedoxygen saturation SpO2) with a standard deviation of 1.9 saturationpoints. Conclusions.The tests have shown the capabilities of aspectral light modulator for use as a possible calibration standard for pulseOximeters. If some improvements of the current prototype can be achieved weconclude from the experience with the device that this novel concept for thecalibration of pulse Oximeters is feasible and that it could become animportant tool for assessing the performance of pulse Oximeters.
Ewen D. Johnston - One of the best experts on this subject based on the ideXlab platform.
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
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Oxygen targeting in preterm infants using the Masimo SET Radical pulse Oximeter
Archives of Disease in Childhood-fetal and Neonatal Edition, 2011Co-Authors: Ewen D. Johnston, Peter Brocklehurst, Andrew J. King, Breidge Boyle, Ed Juszczak, Ben StensonAbstract:Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profi les obtained from the Masimo Set Radical pulse Oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse Oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the Oximeter’s internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current Oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available Oximeters, Masimo Oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse Oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board fi rmware V4.8 or higher). Because this observation is likely to infl uence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.
