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Manuel Daconceicao - One of the best experts on this subject based on the ideXlab platform.
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Oxygen saturation during esophagogastroduodenoscopy in children general anesthesia versus intravenous sedation
Journal of Pediatric Gastroenterology and Nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry <90%): no patients in the general anesthesia group had desaturation (50% vs. 0%). In the general anesthesia group, heart rate and mean arterial pressure remained stable during the whole procedure, whereas in the sedation group, heart rate and mean arterial pressure increased significantly during the procedure. The endoscopy satisfaction score was I in all 18 patients in the general anesthesia group, whereas in the sedation group, it was I in only 2 patients, II in 8 patients, and III in 10 patients. Conclusions: These results confirm that hypoxia during upper digestive endoscopy in patients under sedation is a frequent occurrence in children. When compared with sedation, general anesthesia is a safer technique that prevents hypoxia and allows the gastroenterologist to perform the endoscopy under better conditions.
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Oxygen saturation during esophagogastroduodenoscopy in children: general anesthesia versus intravenous sedation.
Journal of pediatric gastroenterology and nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry
T. Lamireau - One of the best experts on this subject based on the ideXlab platform.
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Oxygen saturation during esophagogastroduodenoscopy in children general anesthesia versus intravenous sedation
Journal of Pediatric Gastroenterology and Nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry <90%): no patients in the general anesthesia group had desaturation (50% vs. 0%). In the general anesthesia group, heart rate and mean arterial pressure remained stable during the whole procedure, whereas in the sedation group, heart rate and mean arterial pressure increased significantly during the procedure. The endoscopy satisfaction score was I in all 18 patients in the general anesthesia group, whereas in the sedation group, it was I in only 2 patients, II in 8 patients, and III in 10 patients. Conclusions: These results confirm that hypoxia during upper digestive endoscopy in patients under sedation is a frequent occurrence in children. When compared with sedation, general anesthesia is a safer technique that prevents hypoxia and allows the gastroenterologist to perform the endoscopy under better conditions.
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Oxygen saturation during esophagogastroduodenoscopy in children: general anesthesia versus intravenous sedation.
Journal of pediatric gastroenterology and nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry
Christos Paizis - One of the best experts on this subject based on the ideXlab platform.
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Cardiorespiratory Changes During Prolonged Downhill Versus Uphill Treadmill Exercise
International Journal of Sports Medicine, 2020Co-Authors: Yoann Garnier, Romuald Lepers, Hervé Assadi, Christos PaizisAbstract:Oxygen uptake (V̇O2), heart rate (HR), energy cost (EC) and Oxygen Pulse are lower during downhill compared to level or uphill locomotion. However, a change in Oxygen Pulse and EC during prolonged grade exercise is not well documented. This study investigated changes in cardiorespiratory responses and EC during 45-min grade exercises. Nine male healthy volunteers randomly ran at 75% HR reserve during 45-min exercise in a level (+1%), uphill (+15%) or downhill (-15%) condition. V̇O2 , minute ventilation (V̇E ) and end-tidal carbon dioxide (PetCO2) were recorded continuously with 5-min averaging between the 10th and 15th min (T1) and 40th and 45th min (T2). For a similar HR (157±3 bpm), V̇O2 , V̇E , and PetCO2 were lower during downhill compared to level and uphill conditions (p
Claudio Gil Soares De Araújo - One of the best experts on this subject based on the ideXlab platform.
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Relative peak exercise Oxygen Pulse is related to sudden cardiac death, cardiovascular and all-cause mortality in middle-aged men.
European journal of preventive cardiology, 2018Co-Authors: Jari A. Laukkanen, Sudhir Kurl, Claudio Gil Soares De Araújo, Hassan Khan, S.y. Jae, Marco Guazzi, Setor K KunutsorAbstract:BackgroundPreliminary evidence suggests that peak exercise Oxygen Pulse – peak Oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise Oxygen Pulse with sudden cardiac death, fatal coronary heart disease and cardiovascular disease and all-cause mortality.DesignA prospective study.MethodsPeak exercise Oxygen Pulse was assessed in a maximal cycling test at baseline in 2227 middle-aged men of the Kuopio Ischaemic Heart Disease cohort study using expired gas variables and electrocardiograms. Relative peak exercise Oxygen Pulse was obtained by dividing the absolute value by body weight.ResultsDuring a median follow-up of 26.1 years 1097 subjects died; there were 220 sudden cardiac deaths, 336 fatal coronary heart diseases and 505 fatal cardiovascular diseases. Relative peak exercise Oxygen Pulse (mean 19.5 (4.1) mL per beat/kg/102) was approximately linearly...
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the slope of the Oxygen Pulse curve does not depend on the maximal heart rate in elite soccer players
Clinics, 2011Co-Authors: Raphael R Perim, Gabriel R Signorelli, Jonathan Myers, Ross Arena, Claudio Gil Soares De AraújoAbstract:INTRODUCTION: It is unknown whether an extremely high heart rate can affect Oxygen Pulse profile during progressive maximal exercise in healthy subjects. OBJECTIVE: Our aim was to compare relative Oxygen Pulse (adjusted for body weight) curves in athletes at their maximal heart rate during treadmill cardiopulmonary exercise testing. METHODS: A total of 180 elite soccer players were categorized in quartiles according to their maximum heart rate values (n = 45). Oxygen consumption, maximum heart rate and relative Oxygen Pulse curves in the extreme quartiles, Q1 and Q4, were compared at intervals corresponding to 10% of the total duration of a cardiopulmonary exercise testing. RESULTS: Oxygen consumption was similar among all subjects during cardiopulmonary exercise testing; however subjects in Q1 started to exhibit lower maximum heart rate values when 20% of the test was complete. Conversely, the relative Oxygen Pulse was higher in this group when cardiopulmonary exercise testing was 40% complete (p<.01). Although the slopes of the lines were similar (p = .25), the regression intercepts differed (p<.01) between Q1 and Q4. During the last two minutes of testing, a flat or decreasing Oxygen Pulse was identified in 20% of the soccer players, and this trend was similar between subjects in Q1 and Q4. CONCLUSION: Relative Oxygen Pulse curve slopes, which serve as an indirect and non-invasive surrogate for stroke volume, suggest that the stroke volume is similar in young and aerobically fit subjects regardless of the maximum heart rate reached.
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The slope of the Oxygen Pulse curve does not depend on the maximal heart rate in elite soccer players
Clinics (Sao Paulo Brazil), 2011Co-Authors: Raphael R Perim, Gabriel R Signorelli, Jonathan Myers, Ross Arena, Claudio Gil Soares De AraújoAbstract:INTRODUCTION: It is unknown whether an extremely high heart rate can affect Oxygen Pulse profile during progressive maximal exercise in healthy subjects. OBJECTIVE: Our aim was to compare relative Oxygen Pulse (adjusted for body weight) curves in athletes at their maximal heart rate during treadmill cardiopulmonary exercise testing. METHODS: A total of 180 elite soccer players were categorized in quartiles according to their maximum heart rate values (n = 45). Oxygen consumption, maximum heart rate and relative Oxygen Pulse curves in the extreme quartiles, Q1 and Q4, were compared at intervals corresponding to 10% of the total duration of a cardiopulmonary exercise testing. RESULTS: Oxygen consumption was similar among all subjects during cardiopulmonary exercise testing; however subjects in Q1 started to exhibit lower maximum heart rate values when 20% of the test was complete. Conversely, the relative Oxygen Pulse was higher in this group when cardiopulmonary exercise testing was 40% complete (p
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Long-term stability of the Oxygen Pulse curve during maximal exercise
Clinics (Sao Paulo Brazil), 2011Co-Authors: Ricardo B. Oliveira, Jonathan Myers, Claudio Gil Soares De AraújoAbstract:INTRODUCTION: Exercise Oxygen Pulse (O2 Pulse), a surrogate for stroke volume and arteriovenous Oxygen difference, has emerged as an important variable obtained during cardiopulmonary exercise testing. OBJECTIVES: We hypothesized that the O2 Pulse curve pattern response to a maximal cycling ramp protocol exhibits a stable linear pattern in subjects reevaluated under the same clinical conditions. METHODS: We retrospectively studied 100 adults (80 males), mean age at baseline of 59 + 12 years, who performed two cardiopulmonary exercise testings (median interval was 15 months), for clinical and/or exercise prescription reasons. The relative O2 Pulse was calculated by dividing its absolute value by body weight. Subjects were classified into quintiles of relative O2 Pulse. Cardiopulmonary exercise testing results and the O2 Pulse curve pattern, expressed by its slope and intercept, were compared among quintiles of relative O2 Pulse at both cardiopulmonary exercise testings. RESULTS: After excluding the first minute of CPX (rest-exercise transition), the relative O2 Pulse curve exhibited a linear increase, as demonstrated by high coefficients of determination (R2 from 0.75 to 0.90; p 0.05 for all comparisons; except for intercept in the 5th quintile). CONCLUSION: Excluding the rest-exercise transition, the relative O2 Pulse exhibited a stable linear increase throughout maximal exercise in adults that were retested under same clinical conditions.
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Does peak Oxygen Pulse complement peak Oxygen uptake in risk stratifying patients with heart failure
The American journal of cardiology, 2009Co-Authors: Ricardo B. Oliveira, Claudio Gil Soares De Araújo, Marco Guazzi, Jonathan Myers, Ross Arena, Joshua Abella, Sandra Mandic, Daniel Bensimhon, Paul Chase, Peter H. BrubakerAbstract:There is scarce information regarding the prognostic utility of peak exercise Oxygen Pulse (peak O 2 Pulse), a surrogate for stroke volume, in patients with heart failure (HF). From May 1994 to November 2007, 998 patients with HF underwent cardiopulmonary exercise testing. The ability of peak Oxygen uptake (VO 2 ) and peak O 2 Pulse to predict cardiac events was examined. Peak O 2 Pulse was calculated by dividing peak VO 2 by heart rate at the time peak VO 2 was achieved and was expressed in both milliliters per beat and as a percentage achieved of the age-predicted value. There were 212 cardiac events (176 deaths, 26 transplantations, and 10 left ventricular assist device implantations) over a mean of 28 ± 26 months of follow-up. Peak VO 2 and age-predicted peak O 2 Pulse were demonstrated by univariate and multivariate Cox regression analyses to be independent predictors of mortality (p 2 and age-predicted peak O 2 Pulse ( −1 /min −1 ] and 2 Pulse also predicted mortality in patients in the intermediate range of peak VO 2 (10 to 14 (mL/kg −1 /min −1 )). The 3-year mortality rate for patients in this range who had age-predicted peak O 2 Pulse values 2 −1 /min −1 ). In conclusion, age-predicted peak O 2 Pulse was a strong and independent predictor of cardiac mortality and complemented peak VO 2 in predicting risk in patients with HF.
Marc Dubreuil - One of the best experts on this subject based on the ideXlab platform.
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Oxygen saturation during esophagogastroduodenoscopy in children general anesthesia versus intravenous sedation
Journal of Pediatric Gastroenterology and Nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry <90%): no patients in the general anesthesia group had desaturation (50% vs. 0%). In the general anesthesia group, heart rate and mean arterial pressure remained stable during the whole procedure, whereas in the sedation group, heart rate and mean arterial pressure increased significantly during the procedure. The endoscopy satisfaction score was I in all 18 patients in the general anesthesia group, whereas in the sedation group, it was I in only 2 patients, II in 8 patients, and III in 10 patients. Conclusions: These results confirm that hypoxia during upper digestive endoscopy in patients under sedation is a frequent occurrence in children. When compared with sedation, general anesthesia is a safer technique that prevents hypoxia and allows the gastroenterologist to perform the endoscopy under better conditions.
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Oxygen saturation during esophagogastroduodenoscopy in children: general anesthesia versus intravenous sedation.
Journal of pediatric gastroenterology and nutrition, 1998Co-Authors: T. Lamireau, Marc Dubreuil, Manuel DaconceicaoAbstract:Background: Hypoxia may occur in children undergoing upper digestive endoscopy under sedation. The purpose of this study was to compare the occurrence of desaturation during intravenous sedation with that which occurs during general anesthesia. Methods: Thirty-six patients between 3 months and 6 years old underwent a diagnostic esophagogastroduodenoscopy under sedation (n = 18) or general anesthesia (n = 18). Oxygen Pulse oximetry, heart rate, and mean arterial pressure were monitored throughout the procedure. At the end of the procedure, the operator gave the value of the endoscopy satisfaction score on a scale of I (very good conditions) to IV (impossible procedure). Results: The minimum Oxygen Pulse oximetry value was significantly lower in the sedation group compared with that in the general anesthesia group (89 ± 5 vs. 97 ± 1; p < 0.001). In the general anesthesia group, the Oxygen Pulse oximetry level declined to less than 95% in only one child; but in the sedation group, it declined to less than 95% in 16 patients (5.5% vs. 89%). Nine patients had a profound desaturation in sedation group (Oxygen Pulse oximetry
