Oxygen Therapy

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Jennifer A Whitty - One of the best experts on this subject based on the ideXlab platform.

  • a randomized trial of high flow Oxygen Therapy in infants with bronchiolitis
    The New England Journal of Medicine, 2018
    Co-Authors: Donna Franklin, Franz E Babl, Luregn J Schlapbach, Ed Oakley, Simon Craig, Jocelyn Neutze, Jeremy Furyk, John F Fraser, Mark Jones, Jennifer A Whitty
    Abstract:

    Abstract Background High-flow Oxygen Therapy through a nasal cannula has been increasingly used in infants with bronchiolitis, despite limited high-quality evidence of its efficacy. The efficacy of high-flow Oxygen Therapy through a nasal cannula in settings other than intensive care units (ICUs) is unclear. Methods In this multicenter, randomized, controlled trial, we assigned infants younger than 12 months of age who had bronchiolitis and a need for supplemental Oxygen Therapy to receive either high-flow Oxygen Therapy (high-flow group) or standard Oxygen Therapy (standard-Therapy group). Infants in the standard-Therapy group could receive rescue high-flow Oxygen Therapy if their condition met criteria for treatment failure. The primary outcome was escalation of care due to treatment failure (defined as meeting ≥3 of 4 clinical criteria: persistent tachycardia, tachypnea, hypoxemia, and medical review triggered by a hospital early-warning tool). Secondary outcomes included duration of hospital stay, dur...

Salvatore Maurizio Maggiore - One of the best experts on this subject based on the ideXlab platform.

Magnus Ekstrom - One of the best experts on this subject based on the ideXlab platform.

  • clinical usefulness of long term Oxygen Therapy in adults
    The New England Journal of Medicine, 2016
    Co-Authors: Magnus Ekstrom
    Abstract:

    The fact that we all need Oxygen to survive might make the benefit of supplemental Oxygen in hypoxemia seem obvious. It is not. Long-term Oxygen Therapy was the first treatment to improve prognosis in patients with chronic obstructive pulmonary disease (COPD) and chronic severe hypoxemia.1,2 However, the question of whether long-term Oxygen Therapy is beneficial in moderate hypoxemia has been floating in the air. The literature on the efficacy of long-term Oxygen Therapy requires no librarian. The current indications for its use are based on two unblinded, randomized trials that were conducted in the 1970s and involved a total . . .

Donna Franklin - One of the best experts on this subject based on the ideXlab platform.

  • a randomized trial of high flow Oxygen Therapy in infants with bronchiolitis
    The New England Journal of Medicine, 2018
    Co-Authors: Donna Franklin, Franz E Babl, Luregn J Schlapbach, Ed Oakley, Simon Craig, Jocelyn Neutze, Jeremy Furyk, John F Fraser, Mark Jones, Jennifer A Whitty
    Abstract:

    Abstract Background High-flow Oxygen Therapy through a nasal cannula has been increasingly used in infants with bronchiolitis, despite limited high-quality evidence of its efficacy. The efficacy of high-flow Oxygen Therapy through a nasal cannula in settings other than intensive care units (ICUs) is unclear. Methods In this multicenter, randomized, controlled trial, we assigned infants younger than 12 months of age who had bronchiolitis and a need for supplemental Oxygen Therapy to receive either high-flow Oxygen Therapy (high-flow group) or standard Oxygen Therapy (standard-Therapy group). Infants in the standard-Therapy group could receive rescue high-flow Oxygen Therapy if their condition met criteria for treatment failure. The primary outcome was escalation of care due to treatment failure (defined as meeting ≥3 of 4 clinical criteria: persistent tachycardia, tachypnea, hypoxemia, and medical review triggered by a hospital early-warning tool). Secondary outcomes included duration of hospital stay, dur...

Federica Antonicelli - One of the best experts on this subject based on the ideXlab platform.