P-Selectin Glycoprotein Li

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Tomoko Ishida - One of the best experts on this subject based on the ideXlab platform.

  • Platelets expressing P-Selectin and platelet-derived microparticles in stored platelet concentrates bind to PSGL-1 on filtrated leukocytes.
    Clinical and applied thrombosis hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis Hemostasis, 2000
    Co-Authors: Shosaku Nomura, Fumiko Okamae, Misao Abe, Mika Hosokawa, Manabu Yamaoka, Tetsuji Ohtani, Shuji Onishi, Tatsunori Matsuzaki, Atsuko Teraoka, Tomoko Ishida
    Abstract:

    The levels of interleukin-6 and platelet-derived microparticles (PMPs) were measured in the blood of 137 pa tients with side effects from platelet concentrate (PC) transfu sion with leukocyte removal filtration, P-Selectin-expressing platelet and PMPs in stored PC before and after the filtration, and filtered leukocytes positive for P-Selectin Glycoprotein Li gand-1. The side effects, which were observed in 203 transfu sions for 84 patients with hematologic disease and 53 patients with nonhematologic disease with no significant difference be tween the two groups, included urticaria (75.9%), erythema (18.7%), and fever (17.2%), but no anaphylactic reactions. The levels of interleukin-6 and PMP correlated in both groups, and were significantly higher in the hematologic disease group than in the nonhematologic disease group. The level of PMP, but not interleukin-6, was significantly higher for patients testing posi tive for allergic reaction than for those testing negative. In the stored PC prior to filtrati...

Shosaku Nomura - One of the best experts on this subject based on the ideXlab platform.

  • Platelets expressing P-Selectin and platelet-derived microparticles in stored platelet concentrates bind to PSGL-1 on filtrated leukocytes.
    Clinical and applied thrombosis hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis Hemostasis, 2000
    Co-Authors: Shosaku Nomura, Fumiko Okamae, Misao Abe, Mika Hosokawa, Manabu Yamaoka, Tetsuji Ohtani, Shuji Onishi, Tatsunori Matsuzaki, Atsuko Teraoka, Tomoko Ishida
    Abstract:

    The levels of interleukin-6 and platelet-derived microparticles (PMPs) were measured in the blood of 137 pa tients with side effects from platelet concentrate (PC) transfu sion with leukocyte removal filtration, P-Selectin-expressing platelet and PMPs in stored PC before and after the filtration, and filtered leukocytes positive for P-Selectin Glycoprotein Li gand-1. The side effects, which were observed in 203 transfu sions for 84 patients with hematologic disease and 53 patients with nonhematologic disease with no significant difference be tween the two groups, included urticaria (75.9%), erythema (18.7%), and fever (17.2%), but no anaphylactic reactions. The levels of interleukin-6 and PMP correlated in both groups, and were significantly higher in the hematologic disease group than in the nonhematologic disease group. The level of PMP, but not interleukin-6, was significantly higher for patients testing posi tive for allergic reaction than for those testing negative. In the stored PC prior to filtrati...

Shuji Onishi - One of the best experts on this subject based on the ideXlab platform.

  • Platelets expressing P-Selectin and platelet-derived microparticles in stored platelet concentrates bind to PSGL-1 on filtrated leukocytes.
    Clinical and applied thrombosis hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis Hemostasis, 2000
    Co-Authors: Shosaku Nomura, Fumiko Okamae, Misao Abe, Mika Hosokawa, Manabu Yamaoka, Tetsuji Ohtani, Shuji Onishi, Tatsunori Matsuzaki, Atsuko Teraoka, Tomoko Ishida
    Abstract:

    The levels of interleukin-6 and platelet-derived microparticles (PMPs) were measured in the blood of 137 pa tients with side effects from platelet concentrate (PC) transfu sion with leukocyte removal filtration, P-Selectin-expressing platelet and PMPs in stored PC before and after the filtration, and filtered leukocytes positive for P-Selectin Glycoprotein Li gand-1. The side effects, which were observed in 203 transfu sions for 84 patients with hematologic disease and 53 patients with nonhematologic disease with no significant difference be tween the two groups, included urticaria (75.9%), erythema (18.7%), and fever (17.2%), but no anaphylactic reactions. The levels of interleukin-6 and PMP correlated in both groups, and were significantly higher in the hematologic disease group than in the nonhematologic disease group. The level of PMP, but not interleukin-6, was significantly higher for patients testing posi tive for allergic reaction than for those testing negative. In the stored PC prior to filtrati...

Fumiko Okamae - One of the best experts on this subject based on the ideXlab platform.

  • Platelets expressing P-Selectin and platelet-derived microparticles in stored platelet concentrates bind to PSGL-1 on filtrated leukocytes.
    Clinical and applied thrombosis hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis Hemostasis, 2000
    Co-Authors: Shosaku Nomura, Fumiko Okamae, Misao Abe, Mika Hosokawa, Manabu Yamaoka, Tetsuji Ohtani, Shuji Onishi, Tatsunori Matsuzaki, Atsuko Teraoka, Tomoko Ishida
    Abstract:

    The levels of interleukin-6 and platelet-derived microparticles (PMPs) were measured in the blood of 137 pa tients with side effects from platelet concentrate (PC) transfu sion with leukocyte removal filtration, P-Selectin-expressing platelet and PMPs in stored PC before and after the filtration, and filtered leukocytes positive for P-Selectin Glycoprotein Li gand-1. The side effects, which were observed in 203 transfu sions for 84 patients with hematologic disease and 53 patients with nonhematologic disease with no significant difference be tween the two groups, included urticaria (75.9%), erythema (18.7%), and fever (17.2%), but no anaphylactic reactions. The levels of interleukin-6 and PMP correlated in both groups, and were significantly higher in the hematologic disease group than in the nonhematologic disease group. The level of PMP, but not interleukin-6, was significantly higher for patients testing posi tive for allergic reaction than for those testing negative. In the stored PC prior to filtrati...

Tatsunori Matsuzaki - One of the best experts on this subject based on the ideXlab platform.

  • Platelets expressing P-Selectin and platelet-derived microparticles in stored platelet concentrates bind to PSGL-1 on filtrated leukocytes.
    Clinical and applied thrombosis hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis Hemostasis, 2000
    Co-Authors: Shosaku Nomura, Fumiko Okamae, Misao Abe, Mika Hosokawa, Manabu Yamaoka, Tetsuji Ohtani, Shuji Onishi, Tatsunori Matsuzaki, Atsuko Teraoka, Tomoko Ishida
    Abstract:

    The levels of interleukin-6 and platelet-derived microparticles (PMPs) were measured in the blood of 137 pa tients with side effects from platelet concentrate (PC) transfu sion with leukocyte removal filtration, P-Selectin-expressing platelet and PMPs in stored PC before and after the filtration, and filtered leukocytes positive for P-Selectin Glycoprotein Li gand-1. The side effects, which were observed in 203 transfu sions for 84 patients with hematologic disease and 53 patients with nonhematologic disease with no significant difference be tween the two groups, included urticaria (75.9%), erythema (18.7%), and fever (17.2%), but no anaphylactic reactions. The levels of interleukin-6 and PMP correlated in both groups, and were significantly higher in the hematologic disease group than in the nonhematologic disease group. The level of PMP, but not interleukin-6, was significantly higher for patients testing posi tive for allergic reaction than for those testing negative. In the stored PC prior to filtrati...