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Martha Hickey - One of the best experts on this subject based on the ideXlab platform.

  • fetal head circumference growth in children with specific language impairment
    Archives of Disease in Childhood, 2012
    Co-Authors: Andrew J O Whitehouse, John P Newnham, Stephen R Zubrick, Eve Blair, Martha Hickey
    Abstract:

    Objective To characterise fetal brain growth in children with specific language impairment (SLI). Design A nested case–control study. Setting Perth, Western Australia. Participants Thirty children meeting criteria for SLI at age 10 years were individually matched with a typically developing comparison child on sex, non-verbal ability, fetal gestational age, maternal age at conception, smoking and alcohol intake during pregnancy. Main outcome measures Occipitofrontal head circumference (HC) was measured using ultrasonography at approximately 18 weeks gestation. Femur length provided a measure of fetal length. Occipitofrontal HC was measured at birth and at the 1-year postnatal follow-up using a precise Paper Tape measure, while crown-heel length acted as an index of body length at both time points. Raw data were transformed to z-scores using reference norms. Results The SLI group had a significantly smaller mean HC than the typically developing comparison children at birth, but there was no group difference at 18 weeks gestation or at the 1-year postnatal follow-up. Individual analyses found that 12 SLI children had an HC z-score less than −1 at birth, with three of these cases meeting criteria for microcephaly. There was no group difference in the indices of overall body size at any time point. Conclusions Children with SLI are more likely to have a small HC at birth but not at 18 weeks gestation or infancy, suggesting growth asynchrony in brain development during the second half of pregnancy.

  • brief report a preliminary study of fetal head circumference growth in autism spectrum disorder
    Journal of Autism and Developmental Disorders, 2011
    Co-Authors: Andrew J O Whitehouse, Fiona J Stanley, John P Newnham, Martha Hickey, Craig E Pennell
    Abstract:

    Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a Paper Tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted.

Andrew J O Whitehouse - One of the best experts on this subject based on the ideXlab platform.

  • fetal head circumference growth in children with specific language impairment
    Archives of Disease in Childhood, 2012
    Co-Authors: Andrew J O Whitehouse, John P Newnham, Stephen R Zubrick, Eve Blair, Martha Hickey
    Abstract:

    Objective To characterise fetal brain growth in children with specific language impairment (SLI). Design A nested case–control study. Setting Perth, Western Australia. Participants Thirty children meeting criteria for SLI at age 10 years were individually matched with a typically developing comparison child on sex, non-verbal ability, fetal gestational age, maternal age at conception, smoking and alcohol intake during pregnancy. Main outcome measures Occipitofrontal head circumference (HC) was measured using ultrasonography at approximately 18 weeks gestation. Femur length provided a measure of fetal length. Occipitofrontal HC was measured at birth and at the 1-year postnatal follow-up using a precise Paper Tape measure, while crown-heel length acted as an index of body length at both time points. Raw data were transformed to z-scores using reference norms. Results The SLI group had a significantly smaller mean HC than the typically developing comparison children at birth, but there was no group difference at 18 weeks gestation or at the 1-year postnatal follow-up. Individual analyses found that 12 SLI children had an HC z-score less than −1 at birth, with three of these cases meeting criteria for microcephaly. There was no group difference in the indices of overall body size at any time point. Conclusions Children with SLI are more likely to have a small HC at birth but not at 18 weeks gestation or infancy, suggesting growth asynchrony in brain development during the second half of pregnancy.

  • brief report a preliminary study of fetal head circumference growth in autism spectrum disorder
    Journal of Autism and Developmental Disorders, 2011
    Co-Authors: Andrew J O Whitehouse, Fiona J Stanley, John P Newnham, Martha Hickey, Craig E Pennell
    Abstract:

    Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a Paper Tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted.

Craig E Pennell - One of the best experts on this subject based on the ideXlab platform.

  • brief report a preliminary study of fetal head circumference growth in autism spectrum disorder
    Journal of Autism and Developmental Disorders, 2011
    Co-Authors: Andrew J O Whitehouse, Fiona J Stanley, John P Newnham, Martha Hickey, Craig E Pennell
    Abstract:

    Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a Paper Tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted.

John P Newnham - One of the best experts on this subject based on the ideXlab platform.

  • fetal head circumference growth in children with specific language impairment
    Archives of Disease in Childhood, 2012
    Co-Authors: Andrew J O Whitehouse, John P Newnham, Stephen R Zubrick, Eve Blair, Martha Hickey
    Abstract:

    Objective To characterise fetal brain growth in children with specific language impairment (SLI). Design A nested case–control study. Setting Perth, Western Australia. Participants Thirty children meeting criteria for SLI at age 10 years were individually matched with a typically developing comparison child on sex, non-verbal ability, fetal gestational age, maternal age at conception, smoking and alcohol intake during pregnancy. Main outcome measures Occipitofrontal head circumference (HC) was measured using ultrasonography at approximately 18 weeks gestation. Femur length provided a measure of fetal length. Occipitofrontal HC was measured at birth and at the 1-year postnatal follow-up using a precise Paper Tape measure, while crown-heel length acted as an index of body length at both time points. Raw data were transformed to z-scores using reference norms. Results The SLI group had a significantly smaller mean HC than the typically developing comparison children at birth, but there was no group difference at 18 weeks gestation or at the 1-year postnatal follow-up. Individual analyses found that 12 SLI children had an HC z-score less than −1 at birth, with three of these cases meeting criteria for microcephaly. There was no group difference in the indices of overall body size at any time point. Conclusions Children with SLI are more likely to have a small HC at birth but not at 18 weeks gestation or infancy, suggesting growth asynchrony in brain development during the second half of pregnancy.

  • brief report a preliminary study of fetal head circumference growth in autism spectrum disorder
    Journal of Autism and Developmental Disorders, 2011
    Co-Authors: Andrew J O Whitehouse, Fiona J Stanley, John P Newnham, Martha Hickey, Craig E Pennell
    Abstract:

    Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a Paper Tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted.

Robert S. Reiffel - One of the best experts on this subject based on the ideXlab platform.