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Mirian Nacagami Sotto - One of the best experts on this subject based on the ideXlab platform.
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revisiting langerhans cells in Paracoccidioidomycosis expression of cd207 langerin in human cutaneous and mucosal lesions
Microbes and Infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Felipe Weisshaupt Stegun, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Abstract Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
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Revisiting Langerhans cells in Paracoccidioidomycosis: expression of CD207/langerin in human cutaneous and mucosal lesions.
Microbes and infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Felipe Weisshaupt Stegun, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
Carla Pagliari - One of the best experts on this subject based on the ideXlab platform.
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revisiting langerhans cells in Paracoccidioidomycosis expression of cd207 langerin in human cutaneous and mucosal lesions
Microbes and Infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Felipe Weisshaupt Stegun, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Abstract Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
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Revisiting Langerhans cells in Paracoccidioidomycosis: expression of CD207/langerin in human cutaneous and mucosal lesions.
Microbes and infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Felipe Weisshaupt Stegun, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
Maria Irma Seixas Duarte - One of the best experts on this subject based on the ideXlab platform.
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revisiting langerhans cells in Paracoccidioidomycosis expression of cd207 langerin in human cutaneous and mucosal lesions
Microbes and Infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Felipe Weisshaupt Stegun, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Abstract Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
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Revisiting Langerhans cells in Paracoccidioidomycosis: expression of CD207/langerin in human cutaneous and mucosal lesions.
Microbes and infection, 2011Co-Authors: Carla Pagliari, Elaine Raniero Fernandes, Felipe Weisshaupt Stegun, Wellington Luiz Ferreira Da Silva, Aline Alves De Lima Silva, Maria Irma Seixas Duarte, Mirian Nacagami SottoAbstract:Langerhans cells are identified by the expression of langerin. We detected this molecule in cutaneous and mucosal lesions in Paracoccidioidomycosis, an important infection in Latin America. Langerin+ cells were scarcely distributed, with short dendrites in epidermis and epithelium and were frequent in the dermis and corium, in the inflammatory infiltrate and granulomas. Mucosal lesions presented a higher expression of langerin in lesions with loose granulomas. For the first time we presented the expression of langerin in Paracoccidioidomycosis. Positive cells in dermis and corium could represent migrating Langerhans cells or a new subset of langerin+ cells with a role in Paracoccidioidomycosis.
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Paracoccidioidomycosis in a renal transplant recipient
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1995Co-Authors: Maria Aparecida Shikanai-yasuda, Maria Irma Seixas Duarte, D.f. Nunes, C.s. Lacaz, E. Sabagga, Edson Abdala, Alberto José Da Silva Duarte, Marta Heloísa LopesAbstract:Paracoccidioidomycosis is a fungal infection rarely described in immunodeficient patients. We report a severe case of pulmonary Paracoccidioidomycosis in a renal transplant recipient and demonstrate deficiencies of in vitro lymphocytic transformation assays, skin hypersensitivity tests, as well as low levels of antibodies to Paracoccidioides brasiliensis.
Suzana Cantanhede Orsini Machado De Sousa - One of the best experts on this subject based on the ideXlab platform.
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Oral exfoliative cytology in the diagnosis of Paracoccidioidomycosis.
Acta cytologica, 2001Co-Authors: Marcelo Sivieri De Araújo, Ricardo Alves Mesquita, Luciana Corrêa, Suzana Cantanhede Orsini Machado De SousaAbstract:OBJECTIVE: To assess the efficacy of conventional oral exfoliative cytology as a diagnostic tool in Paracoccidioidomycosis. STUDY DESIGN: Cytologic smears and incisional biopsies were obtained from 10 patients with a clinical suspicion and oral manifestations of Paracoccidioidomycosis. Cytologic smears and sections of the incisional biopsy underwent methenamine silver staining for fungi according to the Gomori-Grocott method. The dry glass slides were examined at 400 or 1,000x magnification, and the presence and shape of yeasts of Paracoccidioides brasiliensis were investigated. RESULTS: Yeasts of the fungus P brasiliensis were clearly identified in cytologic smears and sections from incisional biopsies in all cases analyzed (100.0%). CONCLUSION: Cytology of oral samples proved an effective diagnostic method for the detection of Paracoccidioidomycosis in humans.
Marcelo Sivieri De Araújo - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of cytopathologic exam for diagnosis of oral chronic Paracoccidioidomycosis
Revista da Sociedade Brasileira de Medicina Tropical, 2003Co-Authors: Marcelo Sivieri De Araújo, Suzana C.o.m. Sousa, Dalmo CorreiaAbstract:With the aim of evaluating exfoliative cytology for the diagnosis of Paracoccidioidomycosis oral lesions, eight patients that presented the disease were studied. The presence of fungi was demonstrated in all these cases. It was concluded that the oral exfoliative cytology exam can be effectively used in the diagnosis of Paracoccidioidomycosis and contribute to the therapeutic control of oral forms of this mycosis.
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Oral exfoliative cytology in the diagnosis of Paracoccidioidomycosis.
Acta cytologica, 2001Co-Authors: Marcelo Sivieri De Araújo, Ricardo Alves Mesquita, Luciana Corrêa, Suzana Cantanhede Orsini Machado De SousaAbstract:OBJECTIVE: To assess the efficacy of conventional oral exfoliative cytology as a diagnostic tool in Paracoccidioidomycosis. STUDY DESIGN: Cytologic smears and incisional biopsies were obtained from 10 patients with a clinical suspicion and oral manifestations of Paracoccidioidomycosis. Cytologic smears and sections of the incisional biopsy underwent methenamine silver staining for fungi according to the Gomori-Grocott method. The dry glass slides were examined at 400 or 1,000x magnification, and the presence and shape of yeasts of Paracoccidioides brasiliensis were investigated. RESULTS: Yeasts of the fungus P brasiliensis were clearly identified in cytologic smears and sections from incisional biopsies in all cases analyzed (100.0%). CONCLUSION: Cytology of oral samples proved an effective diagnostic method for the detection of Paracoccidioidomycosis in humans.
