The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
C J Duncan - One of the best experts on this subject based on the ideXlab platform.
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ultrastructural changes in rat kidney mitochondria in response to the oxygen or calcium Paradox
Comparative Biochemistry and Physiology Part A: Physiology, 1994Co-Authors: J W Morton, Helen Mcloughlin, C J DuncanAbstract:Abstract Isolated, perfused rat kidney released lactate dehydrogenase in response to the protocol of a standard oxygen-Paradox or calcium-Paradox. The results are comparable to those found with rat heart. The mitochondria of the proximal tubule cells at the end of the calcium-Paradox were swollen, had mitochondrial bars and were subdivided with internal septa; after the oxygen-Paradox they exhibited, in addition, many myelin figures. Such ultrastructural changes were characteristic of the mitochondria of skeletal and cardiac muscles damaged by a rise in [Ca2+]i,. It is concluded (i) that typical calciumand oxygen-Paradoxes can be produced in kidney, (ii) that these are associated with a rise in [Ca2+]i and (iii) the proximal tubules, in particular, are damaged.
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are oxygen radicals implicated in the calcium Paradox of the rat heart
Journal of Cardiovascular Pharmacology, 1994Co-Authors: Stephanie Daniels, C J DuncanAbstract:No reduction in creatine kinase (CK) release during standard Ca2+ Paradox in the Langendorff-perfused rat heart was afforded by anoxic perfusion, nor by addition of the radical scavengers superoxide dismutase (150,000 U/L), catalase (150,000 U/L), mannitol (15 or 50 mM), dimethylthiourea (DMTU, 10 mM), the antioxidant vitamin E (0.25 or 0.75 mM), or the iron chelator desferrioxamine (0.8 mM). Even under mild Ca(2+)-Paradox conditions, achieved by (a) reducing the duration of the Ca(2+)-free period, (b) increasing [Ca2+]0 during the "Ca(2+)-free" period, or (c) reperfusing with 0.1 mM Ca2+, no protection was achieved by mannitol, DMTU, or desferrioxamine. Perfusion with N2 did not cause a reduction in CK release caused by caffeine or dinitrophenol or Ca2+ Paradox. We conclude that no evidence supports the hypothesis that oxygen radicals are implicated in release of CK in Ca2+ Paradox.
Wendy K Smith - One of the best experts on this subject based on the ideXlab platform.
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our collective tensions Paradox research community s response to covid 19
Journal of Management Inquiry, 2021Co-Authors: Joshua Keller, Wendy K Smith, Marianne W Lewis, Simone Carmine, Paula Jarzabkowski, Camille Pradies, Garima Sharma, Russ VinceAbstract:In this commentary on three articles from dozens of Paradox theory scholars on Paradox approaches to examining the COVID-19 pandemic and how the COVID-19 pandemic informs Paradox theory, the author...
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Paradox research in management science looking back to move forward
The Academy of Management Annals, 2016Co-Authors: Jonathan Schad, Marianne W Lewis, Sebastian Raisch, Wendy K SmithAbstract:Paradox studies offer vital and timely insights into an array of organizational tensions. Yet this field stands at a critical juncture. Over the past 25 years, management scholars have drawn foundational insights from philosophy and psychology to apply a Paradox lens to organizational phenomena. Yet extant studies selectively leverage ancient wisdom, adopting some key insights while abandoning others. Using a structured content analysis to review the burgeoning management literature, we surface six key themes, which represent the building blocks of a meta-theory of Paradox. These six themes received varying attention in extant studies: Paradox scholars emphasize types of Paradoxes, collective approaches, and outcomes, but pay less attention to relationships within Paradoxes, individual approaches, and dynamics. As this analysis suggests, management scholars have increasingly simplified the intricate, often messy phenomena of Paradox. Greater simplicity renders phenomena understandable and testable, however, oversimplifying complex realities can foster reductionist and incomplete theories. We therefore propose a future research agenda targeted at enriching a meta-theory of Paradox by reengaging these less developed themes. Doing so can sharpen the focus of this field, while revisiting its rich conceptual roots to capture the intricacies of Paradox. This future research agenda leverages the potential of Paradox across diverse streams of management science.
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toward a theory of Paradox a dynamic equilibrium model of organizing
Academy of Management Review, 2011Co-Authors: Wendy K Smith, Marianne W LewisAbstract:As organizational environments become more global, dynamic, and competitive, contradictory demands intensify. To understand and explain such tensions, academics and practitioners are increasingly adopting a Paradox lens. We review the Paradox literature, categorizing types and highlighting fundamental debates. We then present a dynamic equilibrium model of organizing, which depicts how cyclical responses to Paradoxical tensions enable sustainability—peak performance in the present that enables success in the future. This review and the model provide the foundation of a theory of Paradox.
Shahriar Akter - One of the best experts on this subject based on the ideXlab platform.
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Explicating the privacy Paradox: A qualitative inquiry of online shopping consumers
Journal of Retailing and Consumer Services, 2019Co-Authors: Ruwan Bandara, Mario Fernando, Shahriar AkterAbstract:Abstract Online consumers often voice discontent and concern over their privacy and yet fail to take adequate precautions. Nor do they abstain from disclosing information. This study aims to explore this phenomenon which is known as the privacy Paradox. Based on semi-structured interviews with online shopping consumers and thematic analysis of data, this paper illuminates the privacy Paradox using three themes: psychological distance of privacy, perceived social contracts of privacy, and learned helplessness and privacy empowerment. Our findings contribute to the privacy Paradox discourse and provide several implications for consumers, online retailers, and policymakers.
Xiaoping Liu - One of the best experts on this subject based on the ideXlab platform.
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privacy Paradox does stated privacy concerns translate into the valuation of personal information
Pacific Asia Conference on Information Systems, 2014Co-Authors: Luvai Motiwalla, Xiaoping LiuAbstract:Information privacy Paradox is of great interest to IS researchers and firms gathering personal information. This Paradox has been found by IS researchers from social, behavioral, and economic aspects independently. However, there is a lack of study that examines the degrees of influence that different factors contribute to the privacy Paradox problem. We combine both economic and social perspectives in our study of the privacy Paradox with an economic valuation of personal information through an auction experiment in first market exchange combined with a behavioral study on general privacy concerns and specific disclosure behaviors. Our goal is to reveal more insights on the Paradox through a privacy auction on personal information. Results indicate that individuals’ privacy concerns do not have a significant influence on their valuations of personal information. Instead, their prior disclosure behaviors in specific situations, like with health-care providers or social networks, are better indicators of their valuations.
Marianne W Lewis - One of the best experts on this subject based on the ideXlab platform.
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our collective tensions Paradox research community s response to covid 19
Journal of Management Inquiry, 2021Co-Authors: Joshua Keller, Wendy K Smith, Marianne W Lewis, Simone Carmine, Paula Jarzabkowski, Camille Pradies, Garima Sharma, Russ VinceAbstract:In this commentary on three articles from dozens of Paradox theory scholars on Paradox approaches to examining the COVID-19 pandemic and how the COVID-19 pandemic informs Paradox theory, the author...
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Paradox research in management science looking back to move forward
The Academy of Management Annals, 2016Co-Authors: Jonathan Schad, Marianne W Lewis, Sebastian Raisch, Wendy K SmithAbstract:Paradox studies offer vital and timely insights into an array of organizational tensions. Yet this field stands at a critical juncture. Over the past 25 years, management scholars have drawn foundational insights from philosophy and psychology to apply a Paradox lens to organizational phenomena. Yet extant studies selectively leverage ancient wisdom, adopting some key insights while abandoning others. Using a structured content analysis to review the burgeoning management literature, we surface six key themes, which represent the building blocks of a meta-theory of Paradox. These six themes received varying attention in extant studies: Paradox scholars emphasize types of Paradoxes, collective approaches, and outcomes, but pay less attention to relationships within Paradoxes, individual approaches, and dynamics. As this analysis suggests, management scholars have increasingly simplified the intricate, often messy phenomena of Paradox. Greater simplicity renders phenomena understandable and testable, however, oversimplifying complex realities can foster reductionist and incomplete theories. We therefore propose a future research agenda targeted at enriching a meta-theory of Paradox by reengaging these less developed themes. Doing so can sharpen the focus of this field, while revisiting its rich conceptual roots to capture the intricacies of Paradox. This future research agenda leverages the potential of Paradox across diverse streams of management science.
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toward a theory of Paradox a dynamic equilibrium model of organizing
Academy of Management Review, 2011Co-Authors: Wendy K Smith, Marianne W LewisAbstract:As organizational environments become more global, dynamic, and competitive, contradictory demands intensify. To understand and explain such tensions, academics and practitioners are increasingly adopting a Paradox lens. We review the Paradox literature, categorizing types and highlighting fundamental debates. We then present a dynamic equilibrium model of organizing, which depicts how cyclical responses to Paradoxical tensions enable sustainability—peak performance in the present that enables success in the future. This review and the model provide the foundation of a theory of Paradox.
