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Roberto Rivera - One of the best experts on this subject based on the ideXlab platform.

  • Interactions between intrauterine contraceptive device use and breast-feeding status at time of intrauterine contraceptive device insertion: analysis of TCu-380A acceptors in developing countries.
    American journal of obstetrics and gynecology, 1992
    Co-Authors: Gaston Farr, Roberto Rivera
    Abstract:

    OBJECTIVE: This paper is a reassessment of earlier findings from a preliminary analysis of data from a multicenter international trial regimen on breast-feeding and non-breast-feeding women in which events related to insertion, expulsion, and removal of the TCu-380A intrauterine contraceptive device (Paragard 380) were investigated. STUDY DESIGN: Performance of the TCu-380A through 12 months after insertion was compared with life-table rate analysis, χ 2 . Fisher exact test, or Student's t test. Variables were events reported during intrauterine contraceptive device insertion and events throughout the 12 months of study participation by breast-feeding status. RESULTS: Breast-feeding among intrauterine contraceptive device users was associated with fewer insertion-related complaints and lower removal rates for bleeding and pain. No uterine perforations were reported throughout the study. CONCLUSION: Differences in the performance of the TCu-380A intrauterine contraceptive device suggest physiologic effects associated with lactational amenorrhea. The TCu-380A intrauterine contraceptive device is a viable option for women breast-feeding at the time of intrauterine contraceptive device insertion.

Sarah Prager - One of the best experts on this subject based on the ideXlab platform.

  • use of the mirena lng ius and Paragard cut380a intrauterine devices in nulliparous women
    Contraception, 2010
    Co-Authors: Richard Lyus, Patricia A Lohr, Sarah Prager
    Abstract:

    Two intrauterine devices (IUDs) are available in the United States the levonorgestrel-bearing intrauterine system (Mirena) and the copper-bearing T380A (Paragard). These devices have very low typical-use failure rates but are used by only a minority of women. In particular there is concern about their use in nulliparous women. We review the available data to address common concerns about using IUDs in this population and show that nulliparous women desiring effective contraception should be considered candidates for IUDs. Copyright © 2010 Elsevier Inc. All rights reserved.

Bahamondes L. - One of the best experts on this subject based on the ideXlab platform.

  • Ease Of Insertion And Clinical Performance Of The Levonorgestrel-releasing Intrauterine System In Nulligravidas
    2015
    Co-Authors: Bahamondes M.v., Hidalgo M.m., Bahamondes L.
    Abstract:

    Background: Despite the high contraceptive efficacy and the additional noncontraceptive benefits of the levonorgestrel-releasing intrauterine system (LNG-IUS), concerns persist with respect to its use in nulligravidas. The objective of this study was to evaluate the ease of insertion and clinical performance of the LNG-IUS in nulligravida women up to 1 year after insertion. Methods: Two cohorts were formed after LNG-IUS insertion, one consisting of 159 nulligravidas and the other of 477 parous women. Each nulligravida women was paired with three parous women who had an LNG-IUS inserted on the same day. Insertion was classified as easy or difficult, and when classified as difficult, the use of Hegar dilators and/or misoprostol and insertion failure were additional factors recorded. Results: In almost 80% of cases, no difficulty was encountered during insertion, and dilators and misoprostol were seldom required; however, when necessary, dilator use was almost threefold higher in nulligravida women. Insertion failed in one nulligravida women and in two parous women. Contraception was the most common reason for insertion, although some of the women received the LNG-IUS for both contraceptive and therapeutic purposes, including heavy menstrual bleeding, hematologic diseases, warfarin use, endometriosis-associated pain and following kidney or liver transplantation. The clinical performance of the device showed zero pregnancy rate, expulsion rates of ∼4/100 women-year and 1-year continuation rate of over 90% in both groups. Conclusions: The LNG-IUS is suitable for use by nulligravidas. It is simple to insert, and its clinical performance in nulligravidas is similar to that found in parous women. © 2011 Elsevier Inc. All rights reserved.845e11e16D'Arcangues, C., Worldwide use of intrauterine devices for contraception (2007) Contraception, 75 (6 SUPPL), pp. 2-S7Special Programme of Research, Development and Research Training in Human Reproduction: Task force on the safety and efficacy of fertility regulating methods. The TCu380A, TCu220C, Multiload 250 and Nova T IUDS at 3, 5 and 7 years of use-results from three randomized multicenter trials (1990) Contraception, 42, pp. 141-158. , World Health OrganizationLuukkainen, T., Toivonen, J., Levonorgestrel-releasing intrauterine IUD as a method of contraception with therapeutic properties (1995) Contraception, 52, pp. 269-276Facts on Contraceptive Use Jan 2008, , http://www.guttmacher.org/pubs/fb_contr_use.pdf, The Guttmacher Institute Available at: (Accessed September 2010)Wellings, K., Zhihong, Z., Krentel, A., Barrett, G., Glasier, A., Attitudes towards long-acting reversible methods of contraception in general practice in the UK (2007) Contraception, 76 (3), pp. 208-214. , DOI 10.1016/j.contraception.2007.05.085, PII S0010782407002879Stanwood, N.L., Garrett, J.M., Konrad, T.R., Obstetrician-gynecologists and the intrauterine device: A survey of attitudes and practice (2002) Obstetrics and Gynecology, 99 (2), pp. 275-280. , DOI 10.1016/S0029-7844(01)01726-4, PII S0029784401017264Black, K.I., Sakhaei, T., Garland, S.M., A study investigating obstetricians' and gynaecologists' management of women requesting an intrauterine device (2010) Aust N Z J Obstet Gynaecol, 50, pp. 184-188Grimes, D.A., Forgettable contraception (2009) Contraception, 80, pp. 497-499Bahamondes, L., Faundes, A., Sobreira-Lima, B., Lui-Filho, J.F., Pecci, P., Matera, S., TCu 380A IUD: A reversible permanent contraceptive method in women over 35 years of age (2005) Contraception, 72 (5), pp. 337-341. , DOI 10.1016/j.contraception.2004.12.026, PII S0010782405001587Sivin, I., Utility and drawbacks of continuous use of a copper T IUD for 20 years (2007) Contraception, 75 (6 SUPPL), pp. 70-S75Hidalgo, M.M., Hidalgo-Regina, C., Bahamondes, M.V., Monteiro, I., Petta, C.A., Bahamondes, L., Serum levonorgestrel levels and endometrial thickness during extended use of the levonorgestrel-releasing intrauterine system (2009) Contraception, 80, pp. 84-89http://www.Paragard.com/health_care_professional/global/pdf/ Prescribing-Info.pdf, Paragard intrauterine copper contraceptive. Prescribing information. Accessed on September 2010http://berlex.bayerhealthcare.com/html/products/pi/Mirena_PI.pdf, Mirena® highlights of prescribing information. Accessed on September 2010Medical Eligibility Criteria for Contraceptive Use, , http://www.who.int/reproductivehealth/publications/family_planning/ 9789241563888/en/, World Health Organization Accessed on September 2010Suhonen, S., Haukkamaa, M., Jakobsson, T., Rauramo, I., Clinical performance of a levonorgestrel-releasing intrauterine system and oral contraceptives in young nulliparous women: A comparative study (2004) Contraception, 69 (5), pp. 407-412. , DOI 10.1016/j.contraception.2003.11.008, PII S0010782403003044Brockmeyer, A., Kishen, M., Webb, A., Experience of IUD/IUS insertions and clinical performance in nulliparous women - A pilot study (2008) Eur J Contracept Reprod Health Care, 13, pp. 248-254Lyus, R., Lohr, P., Prager, S., Use of the Mirena LNG-IUS and Paragard CuT380A intrauterine devices in nulliparous women (2010) Contraception, 81, pp. 367-371. , Board of the Society of Family PlanningTietze, C., Lewit, S., Recommended procedures for the statistical evaluation of intrauterine contraception (1973) Stud Fam Plann, 4, pp. 35-42Zhou, L., Harrison-Woolrych, M., Coulter, D.M., Use of the New Zealand intensive medicines monitoring programme to study the levonorgestrel-releasing intrauterine device (Mirena) (2003) Pharmacoepidemiology and Drug Safety, 12 (5), pp. 371-377. , DOI 10.1002/pds.875Sivin, I., El Mahgoub, S., McCarthy, T., Mishell Jr., D.R., Shoupe, D., Alvarez, F., Brache, V., Stern, J., Long-term contraception with the levonorgestrel 20 mcg/day (LNg 20) and the Copper T 380Ag intrauterine devices: A five-year randomized study (1990) Contraception, 42 (4), pp. 361-378. , DOI 10.1016/0010-7824(90)90046-XChien, L.W., Liu, W.M., Tzeng, C.R., Au, H.K., Effect of previous live birth and prior route of delivery on the outcome of early medical abortion (2009) Obstet Gynecol, 113, pp. 669-674Ofili-Yebovi, D., Ben-Nagi, J., Sawyer, E., Yazbek, J., Lee, C., Gonzalez, J., Jurkovic, D., Deficient lower-segment Cesarean section scars: Prevalence and risk factors (2008) Ultrasound in Obstetrics and Gynecology, 31 (1), pp. 72-77. , DOI 10.1002/uog.5200Ngai, S.W., Chan, Y.M., Tang, O.S., Ho, P.C., The use of misoprostol for pre-operative cervical dilatation prior to vacuum aspiration: A randomized trial (1999) Human Reproduction, 14 (8), pp. 2139-2142. , DOI 10.1093/humrep/14.8.2139Ngai, S.W., Tang, O.S., Ho, P.C., Randomized comparison of vaginal (200 microg every 3 h) and oral (400 microg every 3 h) misoprostol when combined with mifepristone in termination of second trimester pregnancy (2000) Hum Reprod, 15, pp. 2205-2208Saav, I., Aronsson, A., Marions, L., Stephansson, O., Gemzell-Danielsson, K., Cervical priming with sublingual misoprostol prior to insertion of an intrauterine device in nulliparous women: A randomized controlled trial (2007) Human Reproduction, 22 (10), pp. 2647-2652. , DOI 10.1093/humrep/dem244Heikinheimo, O., Inki, P., Kunz, M., Double-blind, randomized, placebo-controlled study on the effect of misoprostol on ease of consecutive insertion of the levonorgestrel-releasing intrauterine system (2010) Contraception, 81, pp. 481-486El-Refaey, H., Rajasekar, D., Abdalla, M., Calder, L., Templeton, A., Induction of abortion with mifepristone (RU 486) and oral or vaginal misoprostol (1995) N Engl J Med, 332, pp. 983-987Dhs, M., Demographic and Health Surveys, , http://www.measuredhs.com/pubs/pub, details.cfm?ID=119&srchTp=. Accessed on September 2010Kaunitz, A.M., Bissonnette, F., Monteiro, I., Lukkari-Lax, E., Muysers, C., Jensen, J.T., Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: A randomized controlled trial (2010) Obstet Gynecol, 116, pp. 625-632. , [Erratum in: Obstet Gynecol 2010;116:999]Fraser, I.S., Non-contraceptive health benefits of intrauterine hormonal systems (2010) Contraception, 82, pp. 396-403Petta, C.A., Ferriani, R.A., Abrão, M.S., A 3-year follow-up of women with endometriosis and pelvic pain users of the levonorgestrel-releasing intrauterine system (2009) Eur J Obstet Gynecol Reprod Biol, 143, pp. 128-129Wong, A.Y.K., Tang, L.C.H., Chin, R.K.H., Levonorgestrel-releasing intrauterine system (Mirena®) and depot medroxyprogesterone acetate (DepoProvera) as long-term maintenance therapy for patients with moderate and severe endometriosis: A randomised controlled trial (2010) Aust N Z J Obstet Gynaecol, 50, pp. 273-279Teitelman, M., Grotegut, C.A., Williams, N.N., Lewis, J.D., The impact of bariatric surgery on menstrual patterns (2006) Obesity Surgery, 16 (11), pp. 1457-1463. , DOI 10.1381/096089206778870148Avgerinos, D.V., Llaguna, O.H., Seigerman, M., Lefkowitz, A.J., Leitman, I.M., Incidence and risk factors for the development of anemia following gastric bypass surgery (2010) World J Gastroenterol, 16, pp. 1867-1870Culwell, K.R., Curtis, K.M., Del Carmen Cravioto, M., Safety of contraceptive method use among women with systemic lupus erythematosus: A systematic review (2009) Obstet Gynecol, 114, pp. 341-353Paulen, M.E., Folger, S.G., Curtis, K.M., Jamieson, D.J., Contraceptive use among solid organ transplant patients: A systematic review (2010) Contraception, 82, pp. 102-112Diaz, J., Bahamondes, L., Monteiro, I., Petta, C., Hildalgo, M.M., Arce, X.E., Acceptability and performance of the levonorgestrel-releasing intrauterine system (Mirena) in Campinas, Brazil (2000) Contraception, 62, pp. 59-61Backman, T., Huhtala, S., Luoto, R., Tuominen, J., Rauramo, I., Koskenvuo, M., Advance information improves user satisfaction with the levonorgestrel intrauterine system (2002) Obstetrics and Gynecology, 99 (4), pp. 608-613. , DOI 10.1016/S0029-7844(01)01764-1, PII S002978440101764

  • Assessment Of The Use Of Two New Low-dose Levonorgestrel-releasing Intrauterine Systems As Contraceptives
    2015
    Co-Authors: Bahamondes L., Bahamondes M.v.
    Abstract:

    [No abstract available]83235238D'Arcangues, C., Worldwide use of intrauterine devices for contraception (2007) Contraception, 75 (SUPPL. 6), pp. S2-S7Grimes, D.A., Forgettable contraception (2009) Contraception, 80, pp. 497-499Bahamondes, L., Faundes, A., Sobreira-Lima, B., Lui-Filho, J.F., Pecci, P., Matera, S., TCu 380A IUD: A reversible permanent contraceptive method in women over 35 years of age (2005) Contraception, 72, pp. 337-341Sivin, I., Utility and drawbacks of continuous use of a copper T IUD for 20 years (2007) Contraception 75(Suppl. 6, pp. S70-S75Hubacher, D., Copper intrauterine device use by nulliparous women: Review of side effects (2007) Contraception, 75 (SUPPL. 6), pp. S8-S11Wellings, K., Zhihong, Z., Krentel, A., Barretta, G., Glasier, A., Attitudes towards long-Acting reversible methods of contraception in general practice in the UK (2007) Contraception, 76, pp. 208-214Stanwood, N.L., Garrett, J.M., Konrad, T.R., Obstetrician-gynecologists and the intrauterine device: A survey of attitudes and practice (2002) Obstet. Gynecol., 99, pp. 275-280Black, K.I., Sakhaei, T., Garland, S.M., A study investigating obstetricians' and gynaecologists' management of women requesting an intrauterine device (2010) Aust. N. Z. J. Obstet. Gynaecol., 50, pp. 184-188Allen, R.H., Bartz, D., Grimes, D.A., Hubacher, D., O'Brien, P., Interventions for pain with intrauterine device insertion (2009) Cochrane Database Syst. Rev., 3, pp. CD007373Luukkainen, T., Toivonen, J., Levonorgestrel-releasing intrauterine IUD as a method of contraception with therapeutic properties (1995) Contraception, 52, pp. 269-276Canteiro, R., Bahamondes, M.V., Dos Santos Fernandes, A., Espejo-Arce, X., Marchi, M., Bahamondes, L., Length of the endometrial cavity as measured by uterine sounding and ultrasonography in women of different parities (2010) Contraception, 81, pp. 515-519Lyus, R., Lohr, P., Prager, S., Board of the society of family planning. Use of the mirena LNG IUS and Paragard CuT380A intrauterine devices in nulliparous women (2010) Contraception, 81, pp. 367-371Bahamondes, M.V., Hidalgo, M.M., Bahamondes, L., Monteiro, I., Ease of insertion and clinical performance of the levonorgestrel- releasing intrauterine system in nulligravidas (2011) Contraception, 84, pp. E11-E16Gemzell-Danielsson, K., Schellschmidt, I., Apter, D., A randomized, Phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and mirena (2012) Fertil. Steril., 97 (3), pp. 616-622. , e1-3Belsey, E.M., Machin, D., D'Arcangues, C., The analysis of vaginal bleeding patterns induced by fertility regulating methods. world health organization special programme of research, development and research training in human reproduction (1986) Contraception, 34, pp. 253-260Silverberg, S.G., Haukkamaa, M., Arko, H., Nilsson, C.G., Luukkainen, T., Endometrial morphology during long-term use of levonorgestrel-releasing intrauterine devices (1986) Int. J. Gynecol. Pathol., 5, pp. 235-241Hubacher, D., Reyes, V., Lillo, S., Preventing copper intrauterine device removals due to side effects among first-time users: Randomized trial to study the effect of prophylactic ibuprofen (2006) Hum. Rep., 21, pp. 1467-1472Rönnerdag, M., Odlind, V., Health effects of long-term use of the intrauterine levonorgestrel- releasing system. A follow-up study over 12 years of continuous use (1999) Acta Obstet. Gynecol. Scand., 78, pp. 716-721Brockmeyer, A., Kishen, M., Webb, A., Experience of IUD/IUS insertions and clinical performance in nulliparous women - A pilot study (2008) Eur. J. Contracept. Reprod. Health Care, 13, pp. 248-254Kaunitz, A., Bissonnette, F., Monteiro, I., Lukkari-Lax, E., Muysers, C., Jensen, J.T., Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: A randomized controlled trial (2010) Obstet. Gynecol., 116, pp. 625-632. , (2010)erratum in: Obstet. Gynecol. 116 99

  • Practical Advice For Avoidance Of Pain Associated With Insertion Of Intrauterine Contraceptives
    2015
    Co-Authors: Bahamondes L., Mansour D., Fiala C., Kaunitz A.m., Gemzell-danielsson K.
    Abstract:

    Few studies in the scientific literature provide clear direction on the prevention or management of pain associated with intrauterine contraceptive (IUC) placement. Those that have been published have studied small numbers of women and fail to provide definitive conclusions. There are also no guidelines available detailing recognised standard approaches to this problem. The consensus recommendations in this review focus primarily on non-pharmacological and often non-evidence-based interventions. This review includes general considerations, practical recommendations for both routine and more difficult cases and guidance on the optimal choice of instruments. General considerations, including pre-insertion counselling, the setting for the procedure, the confidence and technique of the provider and the interplay between the provider and assistant, can influence women's level of anxiety and, in turn, influence their perception of pain and their overall experience. Further studies are required to refine the optimal strategy for managing pain associated with IUC insertion.4015460Trussell, J., Contraceptive failure in the United States (2011) Contraception, 83, pp. 397-404Winner, B., Peipert, J.F., Zhao, Q., Effectiveness of long-acting reversible contraception (2012) N Engl J Med, 366, pp. 1998-2007Lyus, R., Lohr, P., Prager, S., Use of the Mirena LNG-IUS and Paragard CuT380A intrauterine devices in nulliparous women (2010) Contraception, 81, pp. 367-371(2011) Clinical Knowledge Summaries. UK Medical Eligibility Criteria for Use of the Levonorgestrel-releasing Intrauterine System, , http://www.cks.nhs.uk/contraception_ius_iud/management/ scenario_intrauterine_system/starting_a_levonorgestrel_releasing_ius/ uk_medical_eligibility_criteria, National Institute for Health and Care Excellence accessed 26 November 2012(2011) Clinical Knowledge Summaries. UK Medical Eligibility Criteria for Use of Copper Intrauterine Devices, , http://www.cks.nhs.uk/contraception_ius_iud/management/ scenario_intrauterine_device/starting_an_iud/uk_medical_eligibility_criteria, National Institute for Health and Care Excellence. accessed 26 November 2012(2010) Medical Eligibility Criteria for Contraceptive Use, , http://www.who.int/reproductivehealth/publications/family_planning/ 9789241563888/en/, (4th edn). accessed 26 November 2012(2010) MMWR Early Release: U.S. Medical Eligibility Criteria for Contraceptive Use, 59. , http://www.cdc.gov/mmwr/pdf/rr/rr59e0528.pdf, accessed 26 November 2012Committee Opinion No. 539: Adolescents and long-acting reversible contraception: Implants and intrauterine devices (2012) Obstet Gynecol, 120, pp. 983-988. , ACOG Committee on Practice Bulletins-GynecologyBahamondes, M.V., Hidalgo, M.M., Bahamondes, L., Ease of insertion and clinical performance of the levonorgestrel- releasing intrauterine system in nulligravidas (2011) Contraception, 84, pp. e11-e16Hubacher, D., Reyes, V., Lillo, S., Pain from copper intrauterine device insertion: Randomized trial of prophylactic ibuprofen (2006) Am J Obstet Gynecol, 195, pp. 1272-1277Lassner, K.J., Chen, C.H., Kropsch, L.A., Comparative study of safety and efficacy of IUD insertions by physicians and nursing personnel in Brazil (1995) Bull Pan Am Health Organ, 29, pp. 206-215Chi, I.C., Galich, L.F., Tauber, P.F., Severe pain at interval IUD insertion: A case-control analysis of patient risk factors (1986) Contraception, 34, pp. 483-495Brockmeyer, A., Kishen, M., Webb, A., Experience of IUD/IUS insertions and clinical performance in nulliparous women-a pilot study (2008) Eur J Contracept Reprod Health Care, 13, pp. 248-254Marions, L., Lövkvist, L., Taube, A., Use of the levonorgestrel releasing-intrauterine system in nulliparous women - A non-interventional study in Sweden (2011) Eur J Contracept Reprod Health Care, 16, pp. 126-134Heikinheimo, O., Inki, P., Kunz, M., Double-blind, randomized, placebo-controlled study on the effect of misoprostol on ease of consecutive insertion of the levonorgestrel-releasing intrauterine system (2010) Contraception, 81, pp. 481-486Allen, R.H., Bartz, D., Grimes, D.A., Interventions for pain with intrauterine device insertion (2009) Cochrane Database Syst Rev, 3, pp. CD007373Fiala, C., Gemzell-Danielsson, K., Tang, O.S., Cervical priming with misoprostol prior to transcervical procedures (2007) Int J Gynaecol Obstet, 99 (SUPPL. 2), pp. S168-S171Gemzell-Danielsson, K., Mansour, D., Fiala, C., Management of pain associated with the insertion of intrauterine contraceptives (2013) Hum Reprod Update, 19, pp. 419-427Murty, J., Use and effectiveness of oral analgesia when fitting an intrauterine device (2003) J Fam Plann Reprod Health Care, 29, pp. 150-151Zhou, L., Harrison-Woolrych, M., Coulter, D.M., Use of the New Zealand Intensive Medicines Monitoring Programme to study the levonorgestrel-releasing intrauterine device (Mirena) (2003) Pharmacoepidemiol Drug Saf, 12, pp. 371-377Faúndes, A., Alvarez, F., Díaz, J., A Latin American experience with levonorgestrel IUD (1993) Ann Med, 25, pp. 149-153Sääv, I., Aronsson, A., Marions, L., Cervical priming with sublingual misoprostol prior to insertion of an intrauterine device in nulliparous women: A randomized controlled trial (2007) Hum Reprod, 22, pp. 2647-2652Dijkhuizen, K., Dekkers, O.M., Holleboom, C.A., Vaginal misoprostol prior to insertion of an intrauterine device: An RCT (2011) Hum Reprod, 26, pp. 323-329Gupta, J.K., Johnson, N., Effect of mifepristone on dilatation of the pregnant and non-pregnant cervix (1990) Lancet, 335, pp. 1238-1240(2007) FSRH Guidance (Nov 2007) Intrauterine Contraception, , http://www.fsrh.org/pdfs/CEUGuidanceIntrauterineContraceptionNov07.pdf, accessed 14 March 2013Maguire, K., Davis, A., Rosario Tejeda, L., Intracervical lidocaine gel for intrauterine device insertion: A randomized clinical trial (2012) Contraception, 86, pp. 214-219McNicholas, C.P., Madden, T., Zhao, Q., Cervical lidocaine for IUD insertion pain: A randomized controlled trial (2012) Am J Obstet Gynecol, 207, pp. 384.e1-384.e6Nadelberg, R., (2007) Paracervical Block, , http://www.bostonscientific.com, accessed 26 November 201

  • Considering The Risks And Benefits Of Intrauterine Devices: Should Clinician Advice Now Be Changed?
    2015
    Co-Authors: Bahamondes L., Bahamondes M.v.
    Abstract:

    Intrauterine contraceptives (IUCs) are the most widely used contraceptive method in the world, the two most common models currently in use being the TCu380A intrauterine device and the levonorgestrel-releasing intrauterine system. IUCs and subdermal implants are referred to as 'long-acting reversible contraceptives' because they provide contraception for at least 3 years with a single intervention. Both IUCs and the contraceptive implant have very low rates of contraceptive failure, these rates being similar in women over and under 21 years of age. They are safe, with few side effects, have a high continuation rate and can be used irrespective of age or parity. However, even now, many healthcare professionals discourage the use of these devices by adolescents, young women and nulligravidas, although the WHO makes no restrictions in this respect. IUCs represent an excellent tool for preventing unplanned pregnancy and should be considered as a first-line contraceptive choice for any woman with no medical contraindications. © 2013 Future Medicine Ltd.1011930Grimes, D.A., Forgettable contraception (2009) Contraception, 80 (6), pp. 497-499Bahamondes, L., Faundes, A., Sobreira-Lima, B., Lui-Filho, J.F., Pecci, P., Matera, S., TCu 380A IUD: A reversible permanent contraceptive method in women over 35 years of age (2005) Contraception, 72 (5), pp. 337-341. , DOI 10.1016/j.contraception.2004.12.026, PII S0010782405001587Sivin, I., Utility and drawbacks of continuous use of a copper T IUD for 20 years (2007) Contraception, 75 (6 SUPPL.), pp. S70-S75. , DOI 10.1016/j.contraception.2007.01.016, PII S0010782407000765Luukkainen, T., Toivonen, J., Levonorgestrel-releasing intrauterine IUD as a method of contraception with therapeutic properties (1995) Contraception, 52 (5), pp. 269-276Hidalgo, M.M., Hidalgo-Regina, C., Bahamondes, M.V., Monteiro, I., Petta, C.A., Bahamondes, L., Serum levonorgestrel levels and endometrial thickness during extended use of the levonorgestrel-releasing intrauterine system (2009) Contraception, 80 (1), pp. 84-89Winner, B., Peipert, J.F., Zhao, Q., Effectiveness of long-acting reversible contraception (2012) N. 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Bahamondes M.v. - One of the best experts on this subject based on the ideXlab platform.

  • Ease Of Insertion And Clinical Performance Of The Levonorgestrel-releasing Intrauterine System In Nulligravidas
    2015
    Co-Authors: Bahamondes M.v., Hidalgo M.m., Bahamondes L.
    Abstract:

    Background: Despite the high contraceptive efficacy and the additional noncontraceptive benefits of the levonorgestrel-releasing intrauterine system (LNG-IUS), concerns persist with respect to its use in nulligravidas. The objective of this study was to evaluate the ease of insertion and clinical performance of the LNG-IUS in nulligravida women up to 1 year after insertion. Methods: Two cohorts were formed after LNG-IUS insertion, one consisting of 159 nulligravidas and the other of 477 parous women. Each nulligravida women was paired with three parous women who had an LNG-IUS inserted on the same day. Insertion was classified as easy or difficult, and when classified as difficult, the use of Hegar dilators and/or misoprostol and insertion failure were additional factors recorded. Results: In almost 80% of cases, no difficulty was encountered during insertion, and dilators and misoprostol were seldom required; however, when necessary, dilator use was almost threefold higher in nulligravida women. Insertion failed in one nulligravida women and in two parous women. Contraception was the most common reason for insertion, although some of the women received the LNG-IUS for both contraceptive and therapeutic purposes, including heavy menstrual bleeding, hematologic diseases, warfarin use, endometriosis-associated pain and following kidney or liver transplantation. The clinical performance of the device showed zero pregnancy rate, expulsion rates of ∼4/100 women-year and 1-year continuation rate of over 90% in both groups. Conclusions: The LNG-IUS is suitable for use by nulligravidas. It is simple to insert, and its clinical performance in nulligravidas is similar to that found in parous women. © 2011 Elsevier Inc. 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Prescribing information. Accessed on September 2010http://berlex.bayerhealthcare.com/html/products/pi/Mirena_PI.pdf, Mirena® highlights of prescribing information. Accessed on September 2010Medical Eligibility Criteria for Contraceptive Use, , http://www.who.int/reproductivehealth/publications/family_planning/ 9789241563888/en/, World Health Organization Accessed on September 2010Suhonen, S., Haukkamaa, M., Jakobsson, T., Rauramo, I., Clinical performance of a levonorgestrel-releasing intrauterine system and oral contraceptives in young nulliparous women: A comparative study (2004) Contraception, 69 (5), pp. 407-412. , DOI 10.1016/j.contraception.2003.11.008, PII S0010782403003044Brockmeyer, A., Kishen, M., Webb, A., Experience of IUD/IUS insertions and clinical performance in nulliparous women - A pilot study (2008) Eur J Contracept Reprod Health Care, 13, pp. 248-254Lyus, R., Lohr, P., Prager, S., Use of the Mirena LNG-IUS and Paragard CuT380A intrauterine devices in nulliparous women (2010) Contraception, 81, pp. 367-371. , Board of the Society of Family PlanningTietze, C., Lewit, S., Recommended procedures for the statistical evaluation of intrauterine contraception (1973) Stud Fam Plann, 4, pp. 35-42Zhou, L., Harrison-Woolrych, M., Coulter, D.M., Use of the New Zealand intensive medicines monitoring programme to study the levonorgestrel-releasing intrauterine device (Mirena) (2003) Pharmacoepidemiology and Drug Safety, 12 (5), pp. 371-377. , DOI 10.1002/pds.875Sivin, I., El Mahgoub, S., McCarthy, T., Mishell Jr., D.R., Shoupe, D., Alvarez, F., Brache, V., Stern, J., Long-term contraception with the levonorgestrel 20 mcg/day (LNg 20) and the Copper T 380Ag intrauterine devices: A five-year randomized study (1990) Contraception, 42 (4), pp. 361-378. , DOI 10.1016/0010-7824(90)90046-XChien, L.W., Liu, W.M., Tzeng, C.R., Au, H.K., Effect of previous live birth and prior route of delivery on the outcome of early medical abortion (2009) Obstet Gynecol, 113, pp. 669-674Ofili-Yebovi, D., Ben-Nagi, J., Sawyer, E., Yazbek, J., Lee, C., Gonzalez, J., Jurkovic, D., Deficient lower-segment Cesarean section scars: Prevalence and risk factors (2008) Ultrasound in Obstetrics and Gynecology, 31 (1), pp. 72-77. , DOI 10.1002/uog.5200Ngai, S.W., Chan, Y.M., Tang, O.S., Ho, P.C., The use of misoprostol for pre-operative cervical dilatation prior to vacuum aspiration: A randomized trial (1999) Human Reproduction, 14 (8), pp. 2139-2142. , DOI 10.1093/humrep/14.8.2139Ngai, S.W., Tang, O.S., Ho, P.C., Randomized comparison of vaginal (200 microg every 3 h) and oral (400 microg every 3 h) misoprostol when combined with mifepristone in termination of second trimester pregnancy (2000) Hum Reprod, 15, pp. 2205-2208Saav, I., Aronsson, A., Marions, L., Stephansson, O., Gemzell-Danielsson, K., Cervical priming with sublingual misoprostol prior to insertion of an intrauterine device in nulliparous women: A randomized controlled trial (2007) Human Reproduction, 22 (10), pp. 2647-2652. , DOI 10.1093/humrep/dem244Heikinheimo, O., Inki, P., Kunz, M., Double-blind, randomized, placebo-controlled study on the effect of misoprostol on ease of consecutive insertion of the levonorgestrel-releasing intrauterine system (2010) Contraception, 81, pp. 481-486El-Refaey, H., Rajasekar, D., Abdalla, M., Calder, L., Templeton, A., Induction of abortion with mifepristone (RU 486) and oral or vaginal misoprostol (1995) N Engl J Med, 332, pp. 983-987Dhs, M., Demographic and Health Surveys, , http://www.measuredhs.com/pubs/pub, details.cfm?ID=119&srchTp=. Accessed on September 2010Kaunitz, A.M., Bissonnette, F., Monteiro, I., Lukkari-Lax, E., Muysers, C., Jensen, J.T., Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: A randomized controlled trial (2010) Obstet Gynecol, 116, pp. 625-632. , [Erratum in: Obstet Gynecol 2010;116:999]Fraser, I.S., Non-contraceptive health benefits of intrauterine hormonal systems (2010) Contraception, 82, pp. 396-403Petta, C.A., Ferriani, R.A., Abrão, M.S., A 3-year follow-up of women with endometriosis and pelvic pain users of the levonorgestrel-releasing intrauterine system (2009) Eur J Obstet Gynecol Reprod Biol, 143, pp. 128-129Wong, A.Y.K., Tang, L.C.H., Chin, R.K.H., Levonorgestrel-releasing intrauterine system (Mirena®) and depot medroxyprogesterone acetate (DepoProvera) as long-term maintenance therapy for patients with moderate and severe endometriosis: A randomised controlled trial (2010) Aust N Z J Obstet Gynaecol, 50, pp. 273-279Teitelman, M., Grotegut, C.A., Williams, N.N., Lewis, J.D., The impact of bariatric surgery on menstrual patterns (2006) Obesity Surgery, 16 (11), pp. 1457-1463. , DOI 10.1381/096089206778870148Avgerinos, D.V., Llaguna, O.H., Seigerman, M., Lefkowitz, A.J., Leitman, I.M., Incidence and risk factors for the development of anemia following gastric bypass surgery (2010) World J Gastroenterol, 16, pp. 1867-1870Culwell, K.R., Curtis, K.M., Del Carmen Cravioto, M., Safety of contraceptive method use among women with systemic lupus erythematosus: A systematic review (2009) Obstet Gynecol, 114, pp. 341-353Paulen, M.E., Folger, S.G., Curtis, K.M., Jamieson, D.J., Contraceptive use among solid organ transplant patients: A systematic review (2010) Contraception, 82, pp. 102-112Diaz, J., Bahamondes, L., Monteiro, I., Petta, C., Hildalgo, M.M., Arce, X.E., Acceptability and performance of the levonorgestrel-releasing intrauterine system (Mirena) in Campinas, Brazil (2000) Contraception, 62, pp. 59-61Backman, T., Huhtala, S., Luoto, R., Tuominen, J., Rauramo, I., Koskenvuo, M., Advance information improves user satisfaction with the levonorgestrel intrauterine system (2002) Obstetrics and Gynecology, 99 (4), pp. 608-613. , DOI 10.1016/S0029-7844(01)01764-1, PII S002978440101764

  • Assessment Of The Use Of Two New Low-dose Levonorgestrel-releasing Intrauterine Systems As Contraceptives
    2015
    Co-Authors: Bahamondes L., Bahamondes M.v.
    Abstract:

    [No abstract available]83235238D'Arcangues, C., Worldwide use of intrauterine devices for contraception (2007) Contraception, 75 (SUPPL. 6), pp. S2-S7Grimes, D.A., Forgettable contraception (2009) Contraception, 80, pp. 497-499Bahamondes, L., Faundes, A., Sobreira-Lima, B., Lui-Filho, J.F., Pecci, P., Matera, S., TCu 380A IUD: A reversible permanent contraceptive method in women over 35 years of age (2005) Contraception, 72, pp. 337-341Sivin, I., Utility and drawbacks of continuous use of a copper T IUD for 20 years (2007) Contraception 75(Suppl. 6, pp. S70-S75Hubacher, D., Copper intrauterine device use by nulliparous women: Review of side effects (2007) Contraception, 75 (SUPPL. 6), pp. S8-S11Wellings, K., Zhihong, Z., Krentel, A., Barretta, G., Glasier, A., Attitudes towards long-Acting reversible methods of contraception in general practice in the UK (2007) Contraception, 76, pp. 208-214Stanwood, N.L., Garrett, J.M., Konrad, T.R., Obstetrician-gynecologists and the intrauterine device: A survey of attitudes and practice (2002) Obstet. Gynecol., 99, pp. 275-280Black, K.I., Sakhaei, T., Garland, S.M., A study investigating obstetricians' and gynaecologists' management of women requesting an intrauterine device (2010) Aust. N. Z. J. Obstet. Gynaecol., 50, pp. 184-188Allen, R.H., Bartz, D., Grimes, D.A., Hubacher, D., O'Brien, P., Interventions for pain with intrauterine device insertion (2009) Cochrane Database Syst. Rev., 3, pp. CD007373Luukkainen, T., Toivonen, J., Levonorgestrel-releasing intrauterine IUD as a method of contraception with therapeutic properties (1995) Contraception, 52, pp. 269-276Canteiro, R., Bahamondes, M.V., Dos Santos Fernandes, A., Espejo-Arce, X., Marchi, M., Bahamondes, L., Length of the endometrial cavity as measured by uterine sounding and ultrasonography in women of different parities (2010) Contraception, 81, pp. 515-519Lyus, R., Lohr, P., Prager, S., Board of the society of family planning. Use of the mirena LNG IUS and Paragard CuT380A intrauterine devices in nulliparous women (2010) Contraception, 81, pp. 367-371Bahamondes, M.V., Hidalgo, M.M., Bahamondes, L., Monteiro, I., Ease of insertion and clinical performance of the levonorgestrel- releasing intrauterine system in nulligravidas (2011) Contraception, 84, pp. E11-E16Gemzell-Danielsson, K., Schellschmidt, I., Apter, D., A randomized, Phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and mirena (2012) Fertil. Steril., 97 (3), pp. 616-622. , e1-3Belsey, E.M., Machin, D., D'Arcangues, C., The analysis of vaginal bleeding patterns induced by fertility regulating methods. world health organization special programme of research, development and research training in human reproduction (1986) Contraception, 34, pp. 253-260Silverberg, S.G., Haukkamaa, M., Arko, H., Nilsson, C.G., Luukkainen, T., Endometrial morphology during long-term use of levonorgestrel-releasing intrauterine devices (1986) Int. J. Gynecol. Pathol., 5, pp. 235-241Hubacher, D., Reyes, V., Lillo, S., Preventing copper intrauterine device removals due to side effects among first-time users: Randomized trial to study the effect of prophylactic ibuprofen (2006) Hum. Rep., 21, pp. 1467-1472Rönnerdag, M., Odlind, V., Health effects of long-term use of the intrauterine levonorgestrel- releasing system. A follow-up study over 12 years of continuous use (1999) Acta Obstet. Gynecol. Scand., 78, pp. 716-721Brockmeyer, A., Kishen, M., Webb, A., Experience of IUD/IUS insertions and clinical performance in nulliparous women - A pilot study (2008) Eur. J. Contracept. Reprod. Health Care, 13, pp. 248-254Kaunitz, A., Bissonnette, F., Monteiro, I., Lukkari-Lax, E., Muysers, C., Jensen, J.T., Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: A randomized controlled trial (2010) Obstet. Gynecol., 116, pp. 625-632. , (2010)erratum in: Obstet. Gynecol. 116 99

  • Considering The Risks And Benefits Of Intrauterine Devices: Should Clinician Advice Now Be Changed?
    2015
    Co-Authors: Bahamondes L., Bahamondes M.v.
    Abstract:

    Intrauterine contraceptives (IUCs) are the most widely used contraceptive method in the world, the two most common models currently in use being the TCu380A intrauterine device and the levonorgestrel-releasing intrauterine system. IUCs and subdermal implants are referred to as 'long-acting reversible contraceptives' because they provide contraception for at least 3 years with a single intervention. Both IUCs and the contraceptive implant have very low rates of contraceptive failure, these rates being similar in women over and under 21 years of age. They are safe, with few side effects, have a high continuation rate and can be used irrespective of age or parity. However, even now, many healthcare professionals discourage the use of these devices by adolescents, young women and nulligravidas, although the WHO makes no restrictions in this respect. IUCs represent an excellent tool for preventing unplanned pregnancy and should be considered as a first-line contraceptive choice for any woman with no medical contraindications. © 2013 Future Medicine Ltd.1011930Grimes, D.A., Forgettable contraception (2009) Contraception, 80 (6), pp. 497-499Bahamondes, L., Faundes, A., Sobreira-Lima, B., Lui-Filho, J.F., Pecci, P., Matera, S., TCu 380A IUD: A reversible permanent contraceptive method in women over 35 years of age (2005) Contraception, 72 (5), pp. 337-341. , DOI 10.1016/j.contraception.2004.12.026, PII S0010782405001587Sivin, I., Utility and drawbacks of continuous use of a copper T IUD for 20 years (2007) Contraception, 75 (6 SUPPL.), pp. S70-S75. , DOI 10.1016/j.contraception.2007.01.016, PII S0010782407000765Luukkainen, T., Toivonen, J., Levonorgestrel-releasing intrauterine IUD as a method of contraception with therapeutic properties (1995) Contraception, 52 (5), pp. 269-276Hidalgo, M.M., Hidalgo-Regina, C., Bahamondes, M.V., Monteiro, I., Petta, C.A., Bahamondes, L., Serum levonorgestrel levels and endometrial thickness during extended use of the levonorgestrel-releasing intrauterine system (2009) Contraception, 80 (1), pp. 84-89Winner, B., Peipert, J.F., Zhao, Q., Effectiveness of long-acting reversible contraception (2012) N. 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  • Interactions between intrauterine contraceptive device use and breast-feeding status at time of intrauterine contraceptive device insertion: analysis of TCu-380A acceptors in developing countries.
    American journal of obstetrics and gynecology, 1992
    Co-Authors: Gaston Farr, Roberto Rivera
    Abstract:

    OBJECTIVE: This paper is a reassessment of earlier findings from a preliminary analysis of data from a multicenter international trial regimen on breast-feeding and non-breast-feeding women in which events related to insertion, expulsion, and removal of the TCu-380A intrauterine contraceptive device (Paragard 380) were investigated. STUDY DESIGN: Performance of the TCu-380A through 12 months after insertion was compared with life-table rate analysis, χ 2 . Fisher exact test, or Student's t test. Variables were events reported during intrauterine contraceptive device insertion and events throughout the 12 months of study participation by breast-feeding status. RESULTS: Breast-feeding among intrauterine contraceptive device users was associated with fewer insertion-related complaints and lower removal rates for bleeding and pain. No uterine perforations were reported throughout the study. CONCLUSION: Differences in the performance of the TCu-380A intrauterine contraceptive device suggest physiologic effects associated with lactational amenorrhea. The TCu-380A intrauterine contraceptive device is a viable option for women breast-feeding at the time of intrauterine contraceptive device insertion.

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