Paralytic Syndrome

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Ole Roland Therkildsen - One of the best experts on this subject based on the ideXlab platform.

Christian Sonne - One of the best experts on this subject based on the ideXlab platform.

Aage Kristian Olsen Alstrup - One of the best experts on this subject based on the ideXlab platform.

Jerry R Mendell - One of the best experts on this subject based on the ideXlab platform.

  • acute Paralytic Syndrome in three american men comparison with chinese cases
    JAMA Neurology, 1993
    Co-Authors: Carlayne E Jackson, Richard J Barohn, Jerry R Mendell
    Abstract:

    • Objective. —To define clinically an unusual acute Paralytic Syndrome with features distinctive from those of the Guillain-Barre Syndrome and similar to those described in Chinese children and young adults. Design. —Case series. Setting. —University medical centers. Patients. —Three North American men (mean age, 29 years) who presented with acute symmetric weakness and muscle cramps after a preceding gastrointestinal tract illness. These patients had no sensory symptoms, developed no respiratory insuffiency or facial weakness, and had normal to brisk muscle stretch reflexes. Results. —Results of serial nerve conduction studies were normal except for low-amplitude motor potentials. Needle electromyography revealed diffuse denervation potentials. Cerebrospinal fluid showed an elevated protein level and, in one case, a mild pleocytosis. A sural nerve biopsy specimen in one patient was normal; muscle biopsy specimens showed denervation atrophy. Conclusions. —These cases resemble those described in Chinese children and young adults and may represent a postviral monophasic process affecting the anterior horn cell or distal motor nerve terminal. Further pathologic correlation will be required to identify the exact site of the lesion. Differentiation is important when considering modes of treatment.

A M Jana - One of the best experts on this subject based on the ideXlab platform.

  • enterovirus specific igm responses in children with acute and chronic Paralytic Syndrome
    The Journal of tropical medicine and hygiene, 1995
    Co-Authors: U Tuteja, G Pandya, R Bharagava, D Agarwal, A M Jana
    Abstract:

    Enterovirus specific IgM responses in 51 children aged 0-7 years with acute, clinically diagnosed Paralytic Syndrome and 8 children with chronic paralysis were detected by IgM antibody capture enzyme immunoassay. Twenty-nine out of 51 (56.86%) acute phase sera were positive for enterovirus (Polio, CVB3 and CVA7) IgM antibodies, in 21 of whom poliovirus antibodies were found in close association with CVB3 and CVA7. On the other hand, preponderance of CVA7 specific IgM was detected in 6 out of 8 sera samples of chronically Paralytic children.