Parathyroid Extract

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Christie Bickley - One of the best experts on this subject based on the ideXlab platform.

  • BASIC BIOLOGICAL SCIENCES Effects of Parathyroid Extract on the Rupture Strength of Intact Skin of the Rat
    2016
    Co-Authors: James W. Little, James C. Wilson, Haromon C. Bickley, Christie Bickley
    Abstract:

    Rats were injected with Parathyroid Extract (PTE) to search for possible effects on con-nective tissue of the skin. Rupture strength analysis of skin samples showed a significant increase in strength of skin from PTE-treated rats. The explanation for this effect is not un-derstood at present. The action of Parathyroid hormone on the skeleton, gut, and kidney has been demon-strated thoroughly by a number of investigat-ors.1-3 Recent studies performed in our labor-atory have shown that Parathyroid Extract (PTE) can also accelerate the onset of wound rupture strength.4 This effect is not well un-derstood at present. However, it would seem that PTE may have a direct or indirect influ-ence on the metabolism of connective tissue in the healing wound. The purpose of this study was to establish the effect of PTE * on connec-tive tissue of nonwounded skin. The dermis of growing, unwounded rats was selected for study. Materials and Methods Thirty male Sprague-Dawley rats weigh-ing from 120 to 165 gm were randomized, placed in individual cages, maintained for one week on a regular diet, and then distributed into three groups and treated as follows: group 1 was treated with 1.6 ml of PTE (200 units); group 2 with 1.6 ml of vehicle (1.6 % glycerin and 0.2 % phenol in triple distilled water)

Fuller Albright - One of the best experts on this subject based on the ideXlab platform.

James W. Little - One of the best experts on this subject based on the ideXlab platform.

  • BASIC BIOLOGICAL SCIENCES Effects of Parathyroid Extract on the Rupture Strength of Intact Skin of the Rat
    2016
    Co-Authors: James W. Little, James C. Wilson, Haromon C. Bickley, Christie Bickley
    Abstract:

    Rats were injected with Parathyroid Extract (PTE) to search for possible effects on con-nective tissue of the skin. Rupture strength analysis of skin samples showed a significant increase in strength of skin from PTE-treated rats. The explanation for this effect is not un-derstood at present. The action of Parathyroid hormone on the skeleton, gut, and kidney has been demon-strated thoroughly by a number of investigat-ors.1-3 Recent studies performed in our labor-atory have shown that Parathyroid Extract (PTE) can also accelerate the onset of wound rupture strength.4 This effect is not well un-derstood at present. However, it would seem that PTE may have a direct or indirect influ-ence on the metabolism of connective tissue in the healing wound. The purpose of this study was to establish the effect of PTE * on connec-tive tissue of nonwounded skin. The dermis of growing, unwounded rats was selected for study. Materials and Methods Thirty male Sprague-Dawley rats weigh-ing from 120 to 165 gm were randomized, placed in individual cages, maintained for one week on a regular diet, and then distributed into three groups and treated as follows: group 1 was treated with 1.6 ml of PTE (200 units); group 2 with 1.6 ml of vehicle (1.6 % glycerin and 0.2 % phenol in triple distilled water)

H. Ingalls - One of the best experts on this subject based on the ideXlab platform.

James C. Wilson - One of the best experts on this subject based on the ideXlab platform.

  • BASIC BIOLOGICAL SCIENCES Effects of Parathyroid Extract on the Rupture Strength of Intact Skin of the Rat
    2016
    Co-Authors: James W. Little, James C. Wilson, Haromon C. Bickley, Christie Bickley
    Abstract:

    Rats were injected with Parathyroid Extract (PTE) to search for possible effects on con-nective tissue of the skin. Rupture strength analysis of skin samples showed a significant increase in strength of skin from PTE-treated rats. The explanation for this effect is not un-derstood at present. The action of Parathyroid hormone on the skeleton, gut, and kidney has been demon-strated thoroughly by a number of investigat-ors.1-3 Recent studies performed in our labor-atory have shown that Parathyroid Extract (PTE) can also accelerate the onset of wound rupture strength.4 This effect is not well un-derstood at present. However, it would seem that PTE may have a direct or indirect influ-ence on the metabolism of connective tissue in the healing wound. The purpose of this study was to establish the effect of PTE * on connec-tive tissue of nonwounded skin. The dermis of growing, unwounded rats was selected for study. Materials and Methods Thirty male Sprague-Dawley rats weigh-ing from 120 to 165 gm were randomized, placed in individual cages, maintained for one week on a regular diet, and then distributed into three groups and treated as follows: group 1 was treated with 1.6 ml of PTE (200 units); group 2 with 1.6 ml of vehicle (1.6 % glycerin and 0.2 % phenol in triple distilled water)