The Experts below are selected from a list of 20730 Experts worldwide ranked by ideXlab platform

Hui Qiu - One of the best experts on this subject based on the ideXlab platform.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment.
    Frontiers in neuroscience, 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl's Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl's Gyrus and right supramarginal Gyrus, left Heschl's Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. Negative correlations were present between the FC of the paired brain regions and the duration and pure tone audiometry in the left Heschl's Gyrus and right supramarginal Gyrus in the left-sided hearing impairment group, the FC of the paired brain regions and duration in the left Heschl's Gyrus and left superior Parietal Gyrus, and the FC of the paired brain regions and pure tone audiometry in the right inferior Parietal lobule and right superior frontal Gyrus in the right-sided hearing impairment group. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment
    Frontiers Media S.A., 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl’s Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl’s Gyrus and right supramarginal Gyrus, left Heschl’s Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. In the left-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration and pure tone audiometry were in the left Heschl’s Gyrus and right supramarginal Gyrus. In the right-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration was in the left Heschl’s Gyrus and superior Parietal Gyrus, and with pure tone audiometry was right inferior Parietal lobule and superior frontal Gyrus. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions

Hugo J. Spiers - One of the best experts on this subject based on the ideXlab platform.

  • Dissociation between Dorsal and Ventral Posterior Parietal Cortical Responses to Incidental Changes in Natural Scenes
    PloS one, 2013
    Co-Authors: Lorelei R. Howard, Dharshan Kumaran, H. Freyja Ólafsdóttir, Hugo J. Spiers
    Abstract:

    Background: The posterior Parietal cortex (PPC) is thought to interact with the medial temporal lobe (MTL) to support spatial cognition and topographical memory. While the response of medial temporal lobe regions to topographical stimuli has been intensively studied, much less research has focused on the role of PPC and its functional connectivity with the medial temporal lobe. Methodology/Principle Findings: Here we report a dissociation between dorsal and ventral regions of PPC in response to different types of change in natural scenes using an fMRI adaptation paradigm. During scanning subjects performed an incidental target detection task whilst viewing trial unique sequentially presented pairs of natural scenes, each containing a single prominent object. We observed a dissociation between the superior Parietal Gyrus and the angular Gyrus, with the former showing greater sensitivity to spatial change, and the latter showing greater sensitivity to scene novelty. In addition, we observed that the parahippocampal cortex has increased functional connectivity with the angular Gyrus, but not superior Parietal Gyrus, when subjects view change to the scene content. Conclusions/Significance: Our findings provide support for proposed dissociations between dorsal and ventral regions of PPC and suggest that the dorsal PPC may support the spatial coding of the visual environment even when this information is incidental to the task at hand. Further, through revealing the differential functional interactions of the SPG and AG with the MTL our results help advance our understanding of how the MTL and PPC cooperate to update representations of the world around us.

  • Dissociation between Dorsal and Ventral Posterior Parietal Cortical Responses to Incidental Changes in Natural ScenesOpen URL for this publicationDOI for this publication
    PLOS ONE, 2013
    Co-Authors: Lorelei R. Howard, Dharshan Kumaran, H. Freyja Ólafsdóttir, Hugo J. Spiers
    Abstract:

    Background The posterior Parietal cortex (PPC) is thought to interact with the medial temporal lobe (MTL) to support spatial cognition and topographical memory. While the response of medial temporal lobe regions to topographical stimuli has been intensively studied, much less research has focused on the role of PPC and its functional connectivity with the medial temporal lobe. Methodology/Principle Findings Here we report a dissociation between dorsal and ventral regions of PPC in response to different types of change in natural scenes using an fMRI adaptation paradigm. During scanning subjects performed an incidental target detection task whilst viewing trial unique sequentially presented pairs of natural scenes, each containing a single prominent object. We observed a dissociation between the superior Parietal Gyrus and the angular Gyrus, with the former showing greater sensitivity to spatial change, and the latter showing greater sensitivity to scene novelty. In addition, we observed that the parahippocampal cortex has increased functional connectivity with the angular Gyrus, but not superior Parietal Gyrus, when subjects view change to the scene content. Conclusions/Significance Our findings provide support for proposed dissociations between dorsal and ventral regions of PPC and suggest that the dorsal PPC may support the spatial coding of the visual environment even when this information is incidental to the task at hand. Further, through revealing the differential functional interactions of the SPG and AG with the MTL our results help advance our understanding of how the MTL and PPC cooperate to update representations of the world around us.

Xiaoxiao Xie - One of the best experts on this subject based on the ideXlab platform.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment.
    Frontiers in neuroscience, 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl's Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl's Gyrus and right supramarginal Gyrus, left Heschl's Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. Negative correlations were present between the FC of the paired brain regions and the duration and pure tone audiometry in the left Heschl's Gyrus and right supramarginal Gyrus in the left-sided hearing impairment group, the FC of the paired brain regions and duration in the left Heschl's Gyrus and left superior Parietal Gyrus, and the FC of the paired brain regions and pure tone audiometry in the right inferior Parietal lobule and right superior frontal Gyrus in the right-sided hearing impairment group. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment
    Frontiers Media S.A., 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl’s Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl’s Gyrus and right supramarginal Gyrus, left Heschl’s Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. In the left-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration and pure tone audiometry were in the left Heschl’s Gyrus and right supramarginal Gyrus. In the right-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration was in the left Heschl’s Gyrus and superior Parietal Gyrus, and with pure tone audiometry was right inferior Parietal lobule and superior frontal Gyrus. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions

Lorelei R. Howard - One of the best experts on this subject based on the ideXlab platform.

  • Dissociation between Dorsal and Ventral Posterior Parietal Cortical Responses to Incidental Changes in Natural Scenes
    PloS one, 2013
    Co-Authors: Lorelei R. Howard, Dharshan Kumaran, H. Freyja Ólafsdóttir, Hugo J. Spiers
    Abstract:

    Background: The posterior Parietal cortex (PPC) is thought to interact with the medial temporal lobe (MTL) to support spatial cognition and topographical memory. While the response of medial temporal lobe regions to topographical stimuli has been intensively studied, much less research has focused on the role of PPC and its functional connectivity with the medial temporal lobe. Methodology/Principle Findings: Here we report a dissociation between dorsal and ventral regions of PPC in response to different types of change in natural scenes using an fMRI adaptation paradigm. During scanning subjects performed an incidental target detection task whilst viewing trial unique sequentially presented pairs of natural scenes, each containing a single prominent object. We observed a dissociation between the superior Parietal Gyrus and the angular Gyrus, with the former showing greater sensitivity to spatial change, and the latter showing greater sensitivity to scene novelty. In addition, we observed that the parahippocampal cortex has increased functional connectivity with the angular Gyrus, but not superior Parietal Gyrus, when subjects view change to the scene content. Conclusions/Significance: Our findings provide support for proposed dissociations between dorsal and ventral regions of PPC and suggest that the dorsal PPC may support the spatial coding of the visual environment even when this information is incidental to the task at hand. Further, through revealing the differential functional interactions of the SPG and AG with the MTL our results help advance our understanding of how the MTL and PPC cooperate to update representations of the world around us.

  • Dissociation between Dorsal and Ventral Posterior Parietal Cortical Responses to Incidental Changes in Natural ScenesOpen URL for this publicationDOI for this publication
    PLOS ONE, 2013
    Co-Authors: Lorelei R. Howard, Dharshan Kumaran, H. Freyja Ólafsdóttir, Hugo J. Spiers
    Abstract:

    Background The posterior Parietal cortex (PPC) is thought to interact with the medial temporal lobe (MTL) to support spatial cognition and topographical memory. While the response of medial temporal lobe regions to topographical stimuli has been intensively studied, much less research has focused on the role of PPC and its functional connectivity with the medial temporal lobe. Methodology/Principle Findings Here we report a dissociation between dorsal and ventral regions of PPC in response to different types of change in natural scenes using an fMRI adaptation paradigm. During scanning subjects performed an incidental target detection task whilst viewing trial unique sequentially presented pairs of natural scenes, each containing a single prominent object. We observed a dissociation between the superior Parietal Gyrus and the angular Gyrus, with the former showing greater sensitivity to spatial change, and the latter showing greater sensitivity to scene novelty. In addition, we observed that the parahippocampal cortex has increased functional connectivity with the angular Gyrus, but not superior Parietal Gyrus, when subjects view change to the scene content. Conclusions/Significance Our findings provide support for proposed dissociations between dorsal and ventral regions of PPC and suggest that the dorsal PPC may support the spatial coding of the visual environment even when this information is incidental to the task at hand. Further, through revealing the differential functional interactions of the SPG and AG with the MTL our results help advance our understanding of how the MTL and PPC cooperate to update representations of the world around us.

Xiaowei Han - One of the best experts on this subject based on the ideXlab platform.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment.
    Frontiers in neuroscience, 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl's Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl's Gyrus and right supramarginal Gyrus, left Heschl's Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. Negative correlations were present between the FC of the paired brain regions and the duration and pure tone audiometry in the left Heschl's Gyrus and right supramarginal Gyrus in the left-sided hearing impairment group, the FC of the paired brain regions and duration in the left Heschl's Gyrus and left superior Parietal Gyrus, and the FC of the paired brain regions and pure tone audiometry in the right inferior Parietal lobule and right superior frontal Gyrus in the right-sided hearing impairment group. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions.

  • Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment
    Frontiers Media S.A., 2019
    Co-Authors: Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Pei Liu, Hui Qiu
    Abstract:

    Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain. However, differences between intrinsic functional changes in the brains of patients with left- and those with right-sided long-term hearing impairments are incompletely understood. This study included 67 patients with unilateral hearing impairments (left-sided, 33 patients; right-sided, 34 patients) and 32 healthy controls. All study participants underwent blood oxygenation level dependent resting-state functional magnetic resonance imaging and T1-weighted imaging with three-dimensional fast spoiled gradient-echo sequences. After data preprocessing, fractional amplitude of low frequency (fALFF) and functional connectivity (FC) analyses were used to evaluate differences between patients and healthy controls. When compared with the right-sided hearing impairment group, the left-sided hearing impairment group showed significantly higher fALFF values in the left superior Parietal Gyrus, right inferior Parietal lobule, and right superior frontal Gyrus, whereas it showed significantly lower fALFF values in the left Heschl’s Gyrus, right supramarginal Gyrus, and left superior frontal Gyrus. In the left-sided hearing impairment group, paired brain regions with enhanced FC were the left Heschl’s Gyrus and right supramarginal Gyrus, left Heschl’s Gyrus and left superior Parietal Gyrus, left superior Parietal Gyrus and right inferior Parietal lobule, right inferior Parietal lobule and right superior frontal Gyrus, and left and right superior frontal gyri. In the left-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration and pure tone audiometry were in the left Heschl’s Gyrus and right supramarginal Gyrus. In the right-sided hearing impairment group, the FC of the paired brain regions correlated negatively with the duration was in the left Heschl’s Gyrus and superior Parietal Gyrus, and with pure tone audiometry was right inferior Parietal lobule and superior frontal Gyrus. The intrinsic reintegration mechanisms of the brain appeared to differ between patients with left-sided hearing impairment and those with right-sided hearing impairment, and the severity of hearing impairment was associated with differences in functional integration in certain brain regions