The Experts below are selected from a list of 11082 Experts worldwide ranked by ideXlab platform
Vito Forte - One of the best experts on this subject based on the ideXlab platform.
-
is a plexiform neurofibroma Pathognomonic of neurofibromatosis type i
Laryngoscope, 2004Co-Authors: Sam J Daniel, Vito ForteAbstract:Objectives/Hypothesis: Several prominent textbooks have claimed that a plexiform neurofibroma is Pathognomonic for neurofibromatosis type I. This is not in agreement with the National Institutes of Health criteria, which require two signs to be present, one of which can be a plexiform neurofibroma. Is a plexiform neurofibroma Pathognomonic for neurofibromatosis type I? Study Design: Retrospective chart review. Methods: Fifty-one patients with surgically resected plexiform neurofibromas between the years 1991 and 2001 were identified, and their charts reviewed. The presence and absence of any manifestation of neurofibromatosis type I as detailed in the National Institutes of Health criteria were recorded. The pathology database at the Hospital for Sick Children (HSC) was searched retrospectively. Results: Five of the 51 patients had a single solitary plexiform neurofibroma. They were followed at the neurofibromatosis clinic at the HSC with regular detailed examinations and no other stigmata were found. Conclusion: Although plexiform neurofibromas are highly suggestive of neurofibromatosis type I, they are not Pathognomonic as claimed.
F. Reed Murtagh - One of the best experts on this subject based on the ideXlab platform.
-
Pathognomonic MR imaging findings in Balo concentric sclerosis
AJNR. American journal of neuroradiology, 2001Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. Rojiani, F. Reed MurtaghAbstract:Irregular, concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo concentric sclerosis (BCS), a rare but recognized variant of multiple sclerosis. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be Pathognomonic.
Jonathan Rt Lakey - One of the best experts on this subject based on the ideXlab platform.
-
in quest of Pathognomonic endophenotypic markers of attention deficit hyperactivity disorder adhd potential of eeg based frequency analysis and erps to better detect prevent and manage adhd
Medical Devices : Evidence and Research, 2020Co-Authors: Priya Miranda, Christopher D Cox, Michael Alexander, Slav Danev, Jonathan Rt LakeyAbstract:Attention deficit hyperactivity disorder (ADHD) is a chronic heritable developmental delay psychiatric disorder requiring chronic management, characterized by inattention, hyperactivity, hyperkinectivity and impulsivity. Subjective clinical evaluation still remains crucial in its diagnosis. Discussed are two key aspects in the "characterizing ADHD" and on the quest for objective "Pathognomonic/endophenotypic diagnostic markers of ADHD". The first aspect briefly revolves around issues related to identification of Pathognomonic/endophenotypic diagnostic markers in ADHD. Issues discussed include changes in ADHD definition, remission/persistence and overlapping-symptoms cum shared-heritability with its co-morbid cross-border mental disorders. The second aspect discussed is neurobiological and EEG-based studies on ADHD. Given the neurobiological and temporal aspects of ADHD symptoms the electroencephalograph (EEG) like NeuralScan by Medeia appears as an appropriate tool. The EEGs appropriateness is further enhanced when coupled with suitable behavior/cognitive/motor/psychological tasks/paradigms yielding EEG-based markers like event-related-potential (ERPs like P3 amplitudes and latency), reaction time variability (RTV), Theta:Beta ratio (TBR) and sensorimotor rhythm (SMR). At present, these markers could potentially help in the neurobiological characterization of ADHD and either help in identifying or lay the groundwork for identifying Pathognomonic and/or endophenotypic EEG-based markers enabling its diagnosis, treatment and management.
-
In Quest of Pathognomonic/Endophenotypic Markers of Attention Deficit Hyperactivity Disorder (ADHD): Potential of EEG-Based Frequency Analysis and ERPs to Better Detect, Prevent and Manage ADHD.
eScholarship University of California, 2020Co-Authors: Miranda Priya, Cox, Christopher D, Alexander Michael, Danev Slav, Jonathan Rt LakeyAbstract:Attention deficit hyperactivity disorder (ADHD) is a chronic heritable developmental delay psychiatric disorder requiring chronic management, characterized by inattention, hyperactivity, hyperkinectivity and impulsivity. Subjective clinical evaluation still remains crucial in its diagnosis. Discussed are two key aspects in the "characterizing ADHD" and on the quest for objective "Pathognomonic/endophenotypic diagnostic markers of ADHD". The first aspect briefly revolves around issues related to identification of Pathognomonic/endophenotypic diagnostic markers in ADHD. Issues discussed include changes in ADHD definition, remission/persistence and overlapping-symptoms cum shared-heritability with its co-morbid cross-border mental disorders. The second aspect discussed is neurobiological and EEG-based studies on ADHD. Given the neurobiological and temporal aspects of ADHD symptoms the electroencephalograph (EEG) like NeuralScan by Medeia appears as an appropriate tool. The EEGs appropriateness is further enhanced when coupled with suitable behavior/cognitive/motor/psychological tasks/paradigms yielding EEG-based markers like event-related-potential (ERPs like P3 amplitudes and latency), reaction time variability (RTV), Theta:Beta ratio (TBR) and sensorimotor rhythm (SMR). At present, these markers could potentially help in the neurobiological characterization of ADHD and either help in identifying or lay the groundwork for identifying Pathognomonic and/or endophenotypic EEG-based markers enabling its diagnosis, treatment and management
Ryan D. Murtagh - One of the best experts on this subject based on the ideXlab platform.
-
Pathognomonic MR imaging findings in Balo concentric sclerosis
AJNR. American journal of neuroradiology, 2001Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. Rojiani, F. Reed MurtaghAbstract:Irregular, concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo concentric sclerosis (BCS), a rare but recognized variant of multiple sclerosis. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be Pathognomonic.
-
Pathognomonic MR Imaging Findings in Balo Concentric Sclerosis
2000Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. RojianiAbstract:Summary: Irregular, concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo concentric sclerosis (BCS), a rare but recog-nized variant of multiple sclerosis. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clini-cally, but MR imaging findings noted in this case may be Pathognomonic. Balo concentric sclerosis (BCS) is widely be-lieved to be a rare variant of multiple sclerosis. It may present as clinically similar to multiple scle-rosis, affecting young adults with mild cognitive impairment without frank dementia, or be associ-ated with altered behavior and focal CNS deficits. Historically, the diagnosis was made post mortem or histopathologically in the presence of specifi
Jamie T. Caracciolo - One of the best experts on this subject based on the ideXlab platform.
-
Pathognomonic MR imaging findings in Balo concentric sclerosis
AJNR. American journal of neuroradiology, 2001Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. Rojiani, F. Reed MurtaghAbstract:Irregular, concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo concentric sclerosis (BCS), a rare but recognized variant of multiple sclerosis. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be Pathognomonic.
-
Pathognomonic MR Imaging Findings in Balo Concentric Sclerosis
2000Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. RojianiAbstract:Summary: Irregular, concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo concentric sclerosis (BCS), a rare but recog-nized variant of multiple sclerosis. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clini-cally, but MR imaging findings noted in this case may be Pathognomonic. Balo concentric sclerosis (BCS) is widely be-lieved to be a rare variant of multiple sclerosis. It may present as clinically similar to multiple scle-rosis, affecting young adults with mild cognitive impairment without frank dementia, or be associ-ated with altered behavior and focal CNS deficits. Historically, the diagnosis was made post mortem or histopathologically in the presence of specifi
