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Paolo Carli - One of the best experts on this subject based on the ideXlab platform.
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cutaneous collision tumour melanocytic naevus basal cell carcinoma seborrhoeic keratosis a clinical dermoscopic and Pathological Case report
British Journal of Dermatology, 2005Co-Authors: V. De Giorgi, D Massi, Serena Sestini, Arbara Alfaioli, Giovanna Carelli, Paolo CarliAbstract:The association of contiguous or 'collision' tumours in the same biopsy specimen is not uncommon and is often reported in the literature. The most common association, basal cell carcinoma (BCC) and naevus, is very difficult to diagnose clinically. We describe a 38-year-old woman with a previous history of melanoma, who presented with a modified pigmented lesion of the hip that had begun to change 6 months earlier. Histologically, the lesion was a melanocytic compound naevus and a BCC with a seborrhoeic keratosis. The Case was investigated clinically and by focusing on the dermoscopic features and their Pathological correlates. Cutaneous collision tumours are extremely difficult to diagnose preoperatively, even with the help of dermoscopy, in particular when one of the lesions is melanocytic.
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Multiple pigmented trichoblastomas and syringocystadenoma papilliferum in naevus sebaceous mimicking a malignant melanoma: a clinical dermoscopic-Pathological Case study.
The British journal of dermatology, 2003Co-Authors: V. De Giorgi, Daniela Massi, E. Trez, Barbara Alfaioli, Paolo CarliAbstract:We report a Case of three distinct adnexal neoplasms associated with a naevus sebaceous of the scalp: a nodular pigmented trichoblastoma, a smaller flat pigmented trichoblastoma and a syringocystadenoma papilliferum, and discuss the clinical and histological features of these neoplasms. The clinical manifestation was suggestive of malignant melanoma, a feature that has never been reported before. For the first time in the literature we describe the Case also by means of a noninvasive analysis, i.e. epiluminescence microscopy. In our experience, epiluminescence microscopy does not appear to be more diagnostically accurate than simple clinical examination when diagnosing lesions of the scalp, contrary to other regions.
V. De Giorgi - One of the best experts on this subject based on the ideXlab platform.
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cutaneous collision tumour melanocytic naevus basal cell carcinoma seborrhoeic keratosis a clinical dermoscopic and Pathological Case report
British Journal of Dermatology, 2005Co-Authors: V. De Giorgi, D Massi, Serena Sestini, Arbara Alfaioli, Giovanna Carelli, Paolo CarliAbstract:The association of contiguous or 'collision' tumours in the same biopsy specimen is not uncommon and is often reported in the literature. The most common association, basal cell carcinoma (BCC) and naevus, is very difficult to diagnose clinically. We describe a 38-year-old woman with a previous history of melanoma, who presented with a modified pigmented lesion of the hip that had begun to change 6 months earlier. Histologically, the lesion was a melanocytic compound naevus and a BCC with a seborrhoeic keratosis. The Case was investigated clinically and by focusing on the dermoscopic features and their Pathological correlates. Cutaneous collision tumours are extremely difficult to diagnose preoperatively, even with the help of dermoscopy, in particular when one of the lesions is melanocytic.
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Multiple pigmented trichoblastomas and syringocystadenoma papilliferum in naevus sebaceous mimicking a malignant melanoma: a clinical dermoscopic-Pathological Case study.
The British journal of dermatology, 2003Co-Authors: V. De Giorgi, Daniela Massi, E. Trez, Barbara Alfaioli, Paolo CarliAbstract:We report a Case of three distinct adnexal neoplasms associated with a naevus sebaceous of the scalp: a nodular pigmented trichoblastoma, a smaller flat pigmented trichoblastoma and a syringocystadenoma papilliferum, and discuss the clinical and histological features of these neoplasms. The clinical manifestation was suggestive of malignant melanoma, a feature that has never been reported before. For the first time in the literature we describe the Case also by means of a noninvasive analysis, i.e. epiluminescence microscopy. In our experience, epiluminescence microscopy does not appear to be more diagnostically accurate than simple clinical examination when diagnosing lesions of the scalp, contrary to other regions.
Jakab Csaba - One of the best experts on this subject based on the ideXlab platform.
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A Case of synchronous hepatocellular carcinoma and aortic body chemodectoma in a dog — Pathological Case report
'Akademiai Kiado Zrt.', 2031Co-Authors: Sterczer Ágnes, Németh Tibor, Mándoki Míra, Gálfi Péter, Jakab CsabaAbstract:The authors describe a Case of synchronously occurring (double) tumours, i.e. primary hepatocellular carcinoma and aortic body chemodectoma in a 14-year-old mixed-breed male dog. The tumours were identified during necropsy, following euthanasia. In the last months of its life, the dog showed signs of weakness, anorexia, apathy, inactivity, and abdominal palpation elicited a painful reaction. The primary liver cancer emerged in the left lateral lobe without evidence of any distant metastases. HistoPathological and immunohistochemical investigations revealed a well-differentiated, trabecular, claudin-7-, claudin-5- and pancytokeratin-negative hepatocellular carcinoma. The Ki-67 proliferation index was 33%. During necropsy, a synchronously occurring benign, grade I type aortic body chemodectoma was also detected in the dog. This neuroendocrine tumour showed chromogranin-, synaptophysin-, neuron-specific enolase- and S100 protein-positivity, and the Ki-67 proliferation index was 2%. The authors believe that this is the first description of synchronously occurring hepatocellular carcinoma and aortic body chemodectoma in a dog
Csaba Jakab - One of the best experts on this subject based on the ideXlab platform.
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a Case of synchronous hepatocellular carcinoma and aortic body chemodectoma in a dog Pathological Case report
Acta Veterinaria Hungarica, 2011Co-Authors: Agnes Sterczer, T Nemeth, Mira Mandoki, P Galfi, Csaba JakabAbstract:The authors describe a Case of synchronously occurring (double) tumours, i.e. primary hepatocellular carcinoma and aortic body chemodectoma in a 14-year-old mixed-breed male dog. The tumours were identified during necropsy, following euthanasia. In the last months of its life, the dog showed signs of weakness, anorexia, apathy, inactivity, and abdominal palpation elicited a painful reaction. The primary liver cancer emerged in the left lateral lobe without evidence of any distant metastases. HistoPathological and immunohistochemical investigations revealed a well-differentiated, trabecular, claudin-7-, claudin-5- and pancytokeratin-negative hepatocellular carcinoma. The Ki-67 proliferation index was 33%. During necropsy, a synchronously occurring benign, grade I type aortic body chemodectoma was also detected in the dog. This neuroendocrine tumour showed chromogranin-, synaptophysin-, neuron-specific enolase- and S100 protein-positivity, and the Ki-67 proliferation index was 2%. The authors believe that this is the first description of synchronously occurring hepatocellular carcinoma and aortic body chemodectoma in a dog.
Manuel F Utset - One of the best experts on this subject based on the ideXlab platform.
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ganglioneuromatous paraganglioma of the cauda equina a Pathological Case study
Human Pathology, 2005Co-Authors: Peter Pytel, Thomas Krausz, Robert L Wollmann, Manuel F UtsetAbstract:This study presents a rare Case of compound paraganglioma/ganglioneuroma with comprehensive immunohistochemical studies that reveal strong cytokeratin expression in all components. A 74-year-old woman presented with a mass lesion of the cauda equina. The 1.8-cm tumor showed 3 histomorphologically and immunohistochemically distinct components: typical paragangliomatous neuroendocrine areas, mature ganglion cell-like neuronal areas, and a "neuromatous" proliferation of Schwann cells with admixed axons. As often seen in cauda equina paragangliomas, the neuroendocrine cells were cytokeratin-positive. In addition, immunoreactivity for cytokeratins was also observed in the neurons and axons. This tumor illustrates the broad spectrum of divergent differentiation that can be seen in cells of sympathoadrenal lineage.