The Experts below are selected from a list of 132 Experts worldwide ranked by ideXlab platform
K. Murnaghan - One of the best experts on this subject based on the ideXlab platform.
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Reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders: Part 1—A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADR
European Spine Journal, 2017Co-Authors: Nadège Lemeunier, S. Silva-oolup, N. Chow, D. Southerst, L. Carroll, J. J. Wong, H. Shearer, P. Mastragostino, E. Côté, K. MurnaghanAbstract:Objective To determine the reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. Methods We updated the systematic review of the 2000–2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders. We also searched the literature to identify studies on the reliability and validity of Doppler velocimetry for the evaluation of cervical arteries. Two independent reviewers screened and critically appraised studies. We conducted a best evidence synthesis of low risk of bias studies and ranked the phases of investigations using the classification proposed by Sackett and Haynes . Results We screened 9022 articles and critically appraised 8 studies; all 8 studies had low risk of bias (three reliability and five validity Phase II–III studies). Preliminary evidence suggests that the extension–rotation test may be reliable and has adequate validity to rule out pain arising from facet joints. The evidence suggests variable reliability and preliminary validity for the evaluation of cervical radiculopathy including neurological examination (manual motor testing, dermatomal sensory testing, deep tendon Reflexes, and Pathological Reflex testing), Spurling’s and the upper limb neurodynamic tests. No evidence was found for doppler velocimetry. Conclusions Little evidence exists to support the use of clinical tests to evaluate the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. We found preliminary evidence to support the use of the extension–rotation test, neurological examination, Spurling’s and the upper limb neurodynamic tests.
Nadège Lemeunier - One of the best experts on this subject based on the ideXlab platform.
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Reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders: Part 1—A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADR
European Spine Journal, 2017Co-Authors: Nadège Lemeunier, S. Silva-oolup, N. Chow, D. Southerst, L. Carroll, J. J. Wong, H. Shearer, P. Mastragostino, E. Côté, K. MurnaghanAbstract:Objective To determine the reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. Methods We updated the systematic review of the 2000–2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders. We also searched the literature to identify studies on the reliability and validity of Doppler velocimetry for the evaluation of cervical arteries. Two independent reviewers screened and critically appraised studies. We conducted a best evidence synthesis of low risk of bias studies and ranked the phases of investigations using the classification proposed by Sackett and Haynes . Results We screened 9022 articles and critically appraised 8 studies; all 8 studies had low risk of bias (three reliability and five validity Phase II–III studies). Preliminary evidence suggests that the extension–rotation test may be reliable and has adequate validity to rule out pain arising from facet joints. The evidence suggests variable reliability and preliminary validity for the evaluation of cervical radiculopathy including neurological examination (manual motor testing, dermatomal sensory testing, deep tendon Reflexes, and Pathological Reflex testing), Spurling’s and the upper limb neurodynamic tests. No evidence was found for doppler velocimetry. Conclusions Little evidence exists to support the use of clinical tests to evaluate the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. We found preliminary evidence to support the use of the extension–rotation test, neurological examination, Spurling’s and the upper limb neurodynamic tests.
Yasuto Higashi - One of the best experts on this subject based on the ideXlab platform.
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The Clinical Characteristics of Spinocerebellar Ataxia 36: A Study of 2121 Japanese Ataxia Patients
Movement Disorders, 2012Co-Authors: Katsunobu Sugihara, Hirofumi Maruyama, Hiroyuki Morino, Ryosuke Miyamoto, Hiroki Ueno, Masayasu Matsumoto, Ryuji Kaji, Hiroshi Kitaguchi, M. Yukitake, Yasuto HigashiAbstract:Spinocerebellar ataxia 36 is caused by the expansion of the intronic GGCCTG hexanucleotide repeat in NOP56. The original article describing this condition demonstrated that patients with spinocerebellar ataxia 36 present with tongue atrophy, a finding that had not been seen in previous types of spinocerebellar ataxias. A total of 2121 patients with clinically diagnosed spinocerebellar ataxia participated in the study. We screened our patient samples for spinocerebellar ataxia 36 using the repeat-primed polymerase chain reaction method and also determined the clinical features of spinocerebellar ataxia 36. Of the ataxia cases examined, 12 were identified as spinocerebellar ataxia 36. Of these, 7 cases (6 families) were autosomal dominant, 4 cases (three families) had a positive family history but were not autosomal dominant, and 1 case was sporadic. The average age of onset was 51.7 years, and disease progression was slow. The main symptoms and signs of disease included ataxia, dysarthria, and hyperReflexia. Approximately half the affected patients demonstrated nystagmus, bulging eyes, and a positive Pathological Reflex, although dysphagia, tongue atrophy, and hearing loss were rare. Moreover, the observed atrophy of the cerebellum and brain stem was not severe. The patients identified in this study were concentrated in western Japan. The frequency of spinocerebellar ataxia 36 was approximately 1.2% in the autosomal dominant group, and the age of onset for this condition was later in comparison with other spinocerebellar ataxia subtypes. © 2012 Movement Disorder Society
S. Silva-oolup - One of the best experts on this subject based on the ideXlab platform.
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Reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders: Part 1—A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADR
European Spine Journal, 2017Co-Authors: Nadège Lemeunier, S. Silva-oolup, N. Chow, D. Southerst, L. Carroll, J. J. Wong, H. Shearer, P. Mastragostino, E. Côté, K. MurnaghanAbstract:Objective To determine the reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. Methods We updated the systematic review of the 2000–2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders. We also searched the literature to identify studies on the reliability and validity of Doppler velocimetry for the evaluation of cervical arteries. Two independent reviewers screened and critically appraised studies. We conducted a best evidence synthesis of low risk of bias studies and ranked the phases of investigations using the classification proposed by Sackett and Haynes . Results We screened 9022 articles and critically appraised 8 studies; all 8 studies had low risk of bias (three reliability and five validity Phase II–III studies). Preliminary evidence suggests that the extension–rotation test may be reliable and has adequate validity to rule out pain arising from facet joints. The evidence suggests variable reliability and preliminary validity for the evaluation of cervical radiculopathy including neurological examination (manual motor testing, dermatomal sensory testing, deep tendon Reflexes, and Pathological Reflex testing), Spurling’s and the upper limb neurodynamic tests. No evidence was found for doppler velocimetry. Conclusions Little evidence exists to support the use of clinical tests to evaluate the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. We found preliminary evidence to support the use of the extension–rotation test, neurological examination, Spurling’s and the upper limb neurodynamic tests.
D. Southerst - One of the best experts on this subject based on the ideXlab platform.
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Reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders: Part 1—A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADR
European Spine Journal, 2017Co-Authors: Nadège Lemeunier, S. Silva-oolup, N. Chow, D. Southerst, L. Carroll, J. J. Wong, H. Shearer, P. Mastragostino, E. Côté, K. MurnaghanAbstract:Objective To determine the reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. Methods We updated the systematic review of the 2000–2010 Bone and Joint Decade Task Force on Neck Pain and its Associated Disorders. We also searched the literature to identify studies on the reliability and validity of Doppler velocimetry for the evaluation of cervical arteries. Two independent reviewers screened and critically appraised studies. We conducted a best evidence synthesis of low risk of bias studies and ranked the phases of investigations using the classification proposed by Sackett and Haynes . Results We screened 9022 articles and critically appraised 8 studies; all 8 studies had low risk of bias (three reliability and five validity Phase II–III studies). Preliminary evidence suggests that the extension–rotation test may be reliable and has adequate validity to rule out pain arising from facet joints. The evidence suggests variable reliability and preliminary validity for the evaluation of cervical radiculopathy including neurological examination (manual motor testing, dermatomal sensory testing, deep tendon Reflexes, and Pathological Reflex testing), Spurling’s and the upper limb neurodynamic tests. No evidence was found for doppler velocimetry. Conclusions Little evidence exists to support the use of clinical tests to evaluate the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders. We found preliminary evidence to support the use of the extension–rotation test, neurological examination, Spurling’s and the upper limb neurodynamic tests.