The Experts below are selected from a list of 105813 Experts worldwide ranked by ideXlab platform
Robert L Spitzer - One of the best experts on this subject based on the ideXlab platform.
-
the Patient Health Questionnaire somatic anxiety and depressive symptom scales a systematic review
General Hospital Psychiatry, 2010Co-Authors: Kurt Kroenke, Robert L Spitzer, Janet B W Williams, Bernd LoweAbstract:Abstract Background Depression, anxiety and somatization are the most common mental disorders in primary care as well as medical specialty populations; each is present in at least 5–10% of Patients and frequently comorbid with one another. An efficient means for measuring and monitoring all three conditions would be desirable. Methods Evidence regarding the psychometric and pragmatic characteristics of the Patient Health Questionnaire (PHQ)-9 depression, generalized anxiety disorder (GAD)-7 anxiety and PHQ-15 somatic symptom scales are synthesized from two sources: (1) four multisite cross-sectional studies (three conducted in primary care and one in obstetric-gynecology practices) comprising 9740 Patients, and (2) key studies from the literature that have studied these scales. Results The PHQ-9 and its abbreviated eight-item (PHQ-8) and two-item (PHQ-2) versions have good sensitivity and specificity for detecting depressive disorders. Likewise, the GAD-7 and its abbreviated two-item (GAD-2) version have good operating characteristics for detecting generalized anxiety, panic, social anxiety and post-traumatic stress disorder. The optimal cutpoint is ≥10 on the parent scales (PHQ-9 and GAD-7) and ≥3 on the ultra-brief versions (PHQ-2 and GAD-2). The PHQ-15 is equal or superior to other brief measures for assessing somatic symptoms and screening for somatoform disorders. Cutpoints of 5, 10 and 15 represent mild, moderate and severe symptom levels on all three scales. Sensitivity to change is well-established for the PHQ-9 and emerging albeit not yet definitive for the GAD-7 and PHQ-15. Conclusions The PHQ-9, GAD-7 and PHQ-15 are brief well-validated measures for detecting and monitoring depression, anxiety and somatization.
-
using the Patient Health Questionnaire 9 to measure depression among racially and ethnically diverse primary care Patients
Journal of General Internal Medicine, 2006Co-Authors: Frederick Y Huang, Kurt Kroenke, Henry Chung, Kevin L Delucchi, Robert L SpitzerAbstract:OBJECTIVE: The Patient Health Questionnaire depression scale (PHQ-9) is a well-validated, Diagnostic and Statistical Manual of Mental Disorders—Fourth Edition (DSM-IV) criterion-based measure for diagnosing depression, assessing severity and monitoring treatment response. The performance of most depression scales including the PHQ-9, however, has not been rigorously evaluated in different racial/ethnic populations. Therefore, we compared the factor structure of the PHQ-9 between different racial/ethnic groups as well as the rates of endorsement and differential item functioning (DIF) of the 9 items of the PHQ-9. The presence of DIF would indicate that responses to an individual item differ significantly between groups, controlling for the level of depression.
-
the Patient Health Questionnaire 2 validity of a two item depression screener
Medical Care, 2003Co-Authors: Kurt Kroenke, Robert L Spitzer, Janet B W WilliamsAbstract:Background. A number of self-administered Questionnaires are available for assessing depression severity, including the 9-item Patient Health Questionnaire depression module (PHQ-9). Because even briefer measures might be desirable for use in busy clinical settings or as part of comprehensive Health
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
Kurt Kroenke - One of the best experts on this subject based on the ideXlab platform.
-
Responsiveness of PROMIS and Patient Health Questionnaire (PHQ) Depression Scales in three clinical trials.
Health and quality of life outcomes, 2021Co-Authors: Kurt Kroenke, Matthew J Bair, Jacob Kean, Timothy E Stump, Chen X. Chen, Teresa M. Damush, Erin E. Krebs, Patrick O MonahanAbstract:Background The PROMIS depression scales are reliable and valid measures that have extensive normative data in general population samples. However, less is known about how responsive they are to detect change in clinical settings and how their responsiveness compares to legacy measures. The purpose of this study was to assess and compare the responsiveness of the PROMIS and Patient Health Questionnaire (PHQ) depression scales in three separate samples. Methods We used data from three clinical trials (two in Patients with chronic pain and one in stroke survivors) totaling 651 participants. At both baseline and follow-up, participants completed four PROMIS depression fixed-length scales as well as legacy measures: Patient Health Questionnaire 9-item and 2-item scales (PHQ-9 and PHQ-2) and the SF-36 Mental Health scale. We measured global ratings of depression change, both prospectively and retrospectively, as anchors to classify Patients as improved, unchanged, or worsened. Responsiveness was assessed with standardized response means, statistical tests comparing change groups, and area-under-curve analysis. Results The PROMIS depression and legacy scales had generally comparable responsiveness. Moreover, the four PROMIS depression scales of varying lengths were similarly responsive. In general, measures performed better in detecting depression improvement than depression worsening. For all measures, responsiveness varied based on the study sample and on whether depression improved or worsened. Conclusions Both PROMIS and PHQ depression scales are brief public domain measures that are responsive (i.e., sensitive to change) and thus appropriate as outcome measures in research as well as for monitoring treatment in clinical practice. Trial registration ClinicalTrials.gov ID: NCT01236521, NCT01583985, NCT01507688.
-
Patient Health Questionnaire anxiety and depression scale initial validation in three clinical trials
Psychosomatic Medicine, 2016Co-Authors: Kurt Kroenke, Jingwei Wu, Zhangsheng Yu, Matthew J Bair, Jacob Kean, Timothy E Stump, Patrick O MonahanAbstract:OBJECTIVE: We examine the reliability and validity of the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS)-which combines the nine-item Patient Health Questionnaire depression scale and seven-item Generalized Anxiety Disorder scale-as a composite measure of depression and anxiety. METHODS: Baseline data from 896 Patients enrolled in two primary-care based trials of chronic pain and one oncology-practice-based trial of depression and pain were analyzed. The internal reliability, standard error of measurement, and convergent, construct, and factor structure validity, as well as sensitivity to change of the PHQ-ADS were examined. RESULTS: The PHQ-ADS demonstrated high internal reliability (Cronbach α values of .8 to .9) in all three trials. PHQ-ADS scores can range from 0 to 48 (with higher scores indicating more severe depression/anxiety), and the estimated standard error of measurement was approximately 3 to 4 points. The PHQ-ADS showed strong convergent (most correlations, 0.7-0.8 range) and construct (most correlations, 0.4-0.6 range) validity when examining its association with other mental Health, quality of life, and disability measures. PHQ-ADS cutpoints of 10, 20, and 30 indicated mild, moderate, and severe levels of depression/anxiety, respectively. Bifactor analysis showed sufficient unidimensionality of the PHQ-ADS score. PHQ-ADS change scores at 3 months differentiated (p < .0001) between individuals classified as worse, stable, or improved by a reference measure, providing preliminary evidence for sensitivity to change. CONCLUSIONS: The PHQ-ADS may be a reliable and valid composite measure of depression and anxiety which, if validated in other populations, could be useful as a single measure for jointly assessing two of the most common psychological conditions in clinical practice and research. TRIAL REGISTRATION: Clinicaltrials.gov Identifier: NCT00926588 (SCOPE); NCT00386243 (ESCAPE); NCT00313573 (INCPAD).
-
Patient Health Questionnaire Anxiety and Depression Scale: Initial Validation in Three Clinical Trials.
Psychosomatic medicine, 2016Co-Authors: Kurt Kroenke, Matthew J Bair, Jacob Kean, Timothy E Stump, Patrick O MonahanAbstract:OBJECTIVE We examine the reliability and validity of the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS)-which combines the nine-item Patient Health Questionnaire depression scale and seven-item Generalized Anxiety Disorder scale-as a composite measure of depression and anxiety. METHODS Baseline data from 896 Patients enrolled in two primary-care based trials of chronic pain and one oncology-practice-based trial of depression and pain were analyzed. The internal reliability, standard error of measurement, and convergent, construct, and factor structure validity, as well as sensitivity to change of the PHQ-ADS were examined. RESULTS The PHQ-ADS demonstrated high internal reliability (Cronbach α values of .8 to .9) in all three trials. PHQ-ADS scores can range from 0 to 48 (with higher scores indicating more severe depression/anxiety), and the estimated standard error of measurement was approximately 3 to 4 points. The PHQ-ADS showed strong convergent (most correlations, 0.7-0.8 range) and construct (most correlations, 0.4-0.6 range) validity when examining its association with other mental Health, quality of life, and disability measures. PHQ-ADS cutpoints of 10, 20, and 30 indicated mild, moderate, and severe levels of depression/anxiety, respectively. Bifactor analysis showed sufficient unidimensionality of the PHQ-ADS score. PHQ-ADS change scores at 3 months differentiated (p < .0001) between individuals classified as worse, stable, or improved by a reference measure, providing preliminary evidence for sensitivity to change. CONCLUSIONS The PHQ-ADS may be a reliable and valid composite measure of depression and anxiety which, if validated in other populations, could be useful as a single measure for jointly assessing two of the most common psychological conditions in clinical practice and research. TRIAL REGISTRATION Clinicaltrials.gov Identifier: NCT00926588 (SCOPE); NCT00386243 (ESCAPE); NCT00313573 (INCPAD).
-
the Patient Health Questionnaire somatic anxiety and depressive symptom scales a systematic review
General Hospital Psychiatry, 2010Co-Authors: Kurt Kroenke, Robert L Spitzer, Janet B W Williams, Bernd LoweAbstract:Abstract Background Depression, anxiety and somatization are the most common mental disorders in primary care as well as medical specialty populations; each is present in at least 5–10% of Patients and frequently comorbid with one another. An efficient means for measuring and monitoring all three conditions would be desirable. Methods Evidence regarding the psychometric and pragmatic characteristics of the Patient Health Questionnaire (PHQ)-9 depression, generalized anxiety disorder (GAD)-7 anxiety and PHQ-15 somatic symptom scales are synthesized from two sources: (1) four multisite cross-sectional studies (three conducted in primary care and one in obstetric-gynecology practices) comprising 9740 Patients, and (2) key studies from the literature that have studied these scales. Results The PHQ-9 and its abbreviated eight-item (PHQ-8) and two-item (PHQ-2) versions have good sensitivity and specificity for detecting depressive disorders. Likewise, the GAD-7 and its abbreviated two-item (GAD-2) version have good operating characteristics for detecting generalized anxiety, panic, social anxiety and post-traumatic stress disorder. The optimal cutpoint is ≥10 on the parent scales (PHQ-9 and GAD-7) and ≥3 on the ultra-brief versions (PHQ-2 and GAD-2). The PHQ-15 is equal or superior to other brief measures for assessing somatic symptoms and screening for somatoform disorders. Cutpoints of 5, 10 and 15 represent mild, moderate and severe symptom levels on all three scales. Sensitivity to change is well-established for the PHQ-9 and emerging albeit not yet definitive for the GAD-7 and PHQ-15. Conclusions The PHQ-9, GAD-7 and PHQ-15 are brief well-validated measures for detecting and monitoring depression, anxiety and somatization.
-
using the Patient Health Questionnaire 9 to measure depression among racially and ethnically diverse primary care Patients
Journal of General Internal Medicine, 2006Co-Authors: Frederick Y Huang, Kurt Kroenke, Henry Chung, Kevin L Delucchi, Robert L SpitzerAbstract:OBJECTIVE: The Patient Health Questionnaire depression scale (PHQ-9) is a well-validated, Diagnostic and Statistical Manual of Mental Disorders—Fourth Edition (DSM-IV) criterion-based measure for diagnosing depression, assessing severity and monitoring treatment response. The performance of most depression scales including the PHQ-9, however, has not been rigorously evaluated in different racial/ethnic populations. Therefore, we compared the factor structure of the PHQ-9 between different racial/ethnic groups as well as the rates of endorsement and differential item functioning (DIF) of the 9 items of the PHQ-9. The presence of DIF would indicate that responses to an individual item differ significantly between groups, controlling for the level of depression.
Jesse R. Fann - One of the best experts on this subject based on the ideXlab platform.
-
diagnostic validity of the Patient Health Questionnaire 2 phq 2 among ethiopian adults
Comprehensive Psychiatry, 2016Co-Authors: Bizu Gelaye, Jesse R. Fann, Negussie Deyessa, Yonas Bahretibeb, Dawit Wondimagegn, Ijala Wilson, Hanna Y Berhane, Teshome Shibre Kelkile, Yemane Berhane, Michelle A WilliamsAbstract:Abstract Background The Patient Health Questionnaire-2 (PHQ-2) is an ultra-brief Questionnaire widely used by researchers and clinicians to detect major depressive disorder (MDD). Despite its individual and societal impact, MDD is often undetected and untreated particularly among sub-Saharan Africans. We conducted this study to evaluate the reliability and validity of using the PHQ-2 as a screen for MDD among Ethiopian adults. Methods A total of 926 adults attending outPatient departments in a major referral hospital in Addis Ababa, Ethiopia participated in this study. Construct validity was assessed by examining associations of PHQ-2 scores with World Health Organization Quality of Life (WHO-QOL) domains. We assessed criterion validity and performance characteristics against an independent, blinded, and psychiatrist administered semi-structured Schedules for Clinical Assessment in Neuropsychiatry (SCAN) interview using measures of sensitivity, specificity and receiver operating characteristics (ROC) curves. Results The PHQ-2 items showed good reliability (intraclass correlation coefficient = 0.92). Quality of life, as reflected by subscale scores for four WHO-QOL domains, was significantly lower among Patients with increasing PHQ-2 scores demonstrating good construct validity. ROC analysis and Youden Index showed that a PHQ-2 threshold score of 3 offered optimal discriminatory power with respect to the diagnosis of MDD via the clinical interview (sensitivity = 74% and specificity = 60%). Conclusion The Amharic language version of the PHQ-2 had good sensitivity and fair specificity for detecting MDD compared against a psychiatrist administered SCAN diagnosis. This study provides evidence for the PHQ-2 as a reliable and valid ultra-brief screening tool for initial identification of MDD.
-
validity of the Patient Health Questionnaire 9 for depression screening and diagnosis in east africa
Psychiatry Research-neuroimaging, 2013Co-Authors: Bizu Gelaye, Michelle A Williams, Seblewengel Lemma, Negussie Deyessa, Yonas Bahretibeb, Teshome Shibre, Dawit Wondimagegn, Asnake Lemenhe, Jesse R. FannAbstract:Depression is often underdiagnosed and undertreated in primary care settings, particularly in developing countries. This is, in part, due to challenges resulting from lack of skilled mental Health workers, stigma associated with mental illness, and lack of cross-culturally validated screening instruments. We conducted this study to evaluate the reliability and validity of the Patient Health Questionnaire-9 (PHQ-9) as a screen for diagnosing major depressive disorder among adults in Ethiopia, the second most populous country in sub-Saharan Africa. A total of 926 adults attending outPatient departments in a major referral hospital in Ethiopia participated in this study. We assessed criterion validity and performance characteristics against an independent, blinded, and psychiatrist administered semi-structured Schedules for Clinical Assessment in Neuropsychiatry (SCAN) interview. Overall, the PHQ-9 items showed good internal (Cronbach's alpha=0.81) and test re-test reliability (intraclass correlation coefficient=0.92). A factor analysis confirmed a one-factor structure. Receiver Operating Characteristics (ROC) analysis showed that a PHQ-9 threshold score of 10 offered optimal discriminatory power with respect to diagnosis of major depressive disorder via the clinical interview (sensitivity=86% and specificity=67%). The PHQ-9 appears to be a reliable and valid instrument that may be used to diagnose major depressive disorders among Ethiopian adults.
-
validity of the Patient Health Questionnaire 9 in assessing major depressive disorder during inPatient spinal cord injury rehabilitation
Archives of Physical Medicine and Rehabilitation, 2012Co-Authors: Charles H. Bombardier, Claire Z. Kalpakjian, Denise G. Tate, Daniel E Graves, Joshua R Dyer, Jesse R. FannAbstract:Abstract Bombardier CH, Kalpakjian CZ, Graves DE, Dyer JR, Tate DG, Fann JR. Validity of the Patient Health Questionnaire-9 in assessing major depressive disorder during inPatient spinal cord injury rehabilitation. Objective To investigate the validity of the Patient Health Questionnaire-9 (PHQ-9) depression screening measure in people undergoing acute inPatient rehabilitation for spinal cord injury (SCI). Design We performed a blinded comparison of the PHQ-9 administered by research staff with the major depression module of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID) conducted by a mental Health professional. Setting InPatient rehabilitation units. Participants Participants (N=142) were Patients undergoing acute rehabilitation for traumatic SCI who were at least 18 years of age, English speakers, and without severe cognitive, motor speech, or psychotic disorders. We obtained the SCID on 173 (84%) of 204 eligible Patients. The final sample of 142 Patients (69%) consisted of those who underwent both assessments within 7 days of each other. Interventions Not applicable. Main Outcome Measures PHQ-9 and SCID major depression module. Results Participants were on average 42.2 years of age, 78.2% men, and 81.7% white, and 66.9% had cervical injuries. The optimal PHQ-9 cutoff (≥11) resulted in 35 positive screens (24.6%). Key indices of criterion validity were as follows: sensitivity, 1.00 (95% confidence interval [CI], .73–1.00); specificity, .84 (95% CI, .76–.89); Youden Index, .84; positive predictive value, .40 (95% CI, .24–.58); and negative predictive value, 1.00 (95% CI, .96–1.00). The area under the receiver operator curve was .92, and κ was .50. Total PHQ-9 scores were inversely correlated with subjective Health state and quality of life since SCI. Conclusions The PHQ-9 meets criteria for good diagnostic accuracy compared with a structured diagnostic assessment for major depressive disorder even in the context of inPatient rehabilitation for acute traumatic SCI.
-
Improving measurement properties of the Patient Health Questionnaire-9 with rating scale analysis
Rehabilitation psychology, 2009Co-Authors: Ryan T. Williams, Allen W. Heinemann, Rita K. Bode, Catherine S. Wilson, Jesse R. Fann, Denise G. TateAbstract:OBJECTIVE The goal of this study was to explore the psychometric properties of the Patient Health Questionnaire-9 (PHQ-9; R. L. Spitzer, K. Kroenke, & J. B. W. Williams, 1999). METHOD Factor analysis and Rasch rating scale analysis were used to examine the psychometric properties of the PHQ-9. The sample consisted of 202 adults with spinal cord injury (SCI). RESULTS The PHQ-9 items appear to form a usefully unidimensional scale. One "double-barreled" item, "Moving or speaking so slowly that other people could have noticed or being so fidgety or restless that you've been moving around a lot more than usual," misfit the Rasch model. Category probability curves indicate respondent difficulty in distinguishing between the 2 intermediate rating scale categories: several days and more than half the days. Combining these categories eliminated this problem and resulted in all items fitting the measurement model. CONCLUSIONS The measurement properties of the PHQ-9 can be improved by collapsing rating scale categories and by restructuring several double- and triple-barreled items. Adopting these changes may improve sensitivity in measuring depression after SCI.
-
Validity of the Patient Health Questionnaire-9 in assessing depression following traumatic brain injury.
The Journal of head trauma rehabilitation, 2005Co-Authors: Jesse R. Fann, Charles H. Bombardier, Sureyya Dikmen, Peter C. Esselman, Catherine A. Warms, Erika Pelzer, Holly Rau, Nancy R. TemkinAbstract:Objective To test the validity and reliability of the Patient Health Questionnaire-9 (PHQ-9) for diagnosing major depressive disorder (MDD) among persons with traumatic brain injury (TBI). Design Prospective cohort study. Setting Level I trauma center. Participants 135 adults within 1 year of complicated mild, moderate, or severe TBI. Main outcome measures PHQ-9 Depression Scale, Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID). Results Using a screening criterion of at least 5 PHQ-9 symptoms present at least several days over the last 2 weeks (with one being depressed mood or anhedonia) maximizes sensitivity (0.93) and specificity (0.89) while providing a positive predictive value of 0.63 and a negative predictive value of 0.99 when compared to SCID diagnosis of MDD. Pearson's correlation between the PHQ-9 scores and other depression measures was 0.90 with the Hopkins Symptom Checklist depression subscale and 0.78 with the Hamilton Rating Scale for Depression. Test-retest reliability of the PHQ-9 was r = 0.76 and kappa = 0.46 when using the optimal screening method. Conclusions The PHQ-9 is a valid and reliable screening tool for detecting MDD in persons with TBI.
Janet B W Williams - One of the best experts on this subject based on the ideXlab platform.
-
the Patient Health Questionnaire somatic anxiety and depressive symptom scales a systematic review
General Hospital Psychiatry, 2010Co-Authors: Kurt Kroenke, Robert L Spitzer, Janet B W Williams, Bernd LoweAbstract:Abstract Background Depression, anxiety and somatization are the most common mental disorders in primary care as well as medical specialty populations; each is present in at least 5–10% of Patients and frequently comorbid with one another. An efficient means for measuring and monitoring all three conditions would be desirable. Methods Evidence regarding the psychometric and pragmatic characteristics of the Patient Health Questionnaire (PHQ)-9 depression, generalized anxiety disorder (GAD)-7 anxiety and PHQ-15 somatic symptom scales are synthesized from two sources: (1) four multisite cross-sectional studies (three conducted in primary care and one in obstetric-gynecology practices) comprising 9740 Patients, and (2) key studies from the literature that have studied these scales. Results The PHQ-9 and its abbreviated eight-item (PHQ-8) and two-item (PHQ-2) versions have good sensitivity and specificity for detecting depressive disorders. Likewise, the GAD-7 and its abbreviated two-item (GAD-2) version have good operating characteristics for detecting generalized anxiety, panic, social anxiety and post-traumatic stress disorder. The optimal cutpoint is ≥10 on the parent scales (PHQ-9 and GAD-7) and ≥3 on the ultra-brief versions (PHQ-2 and GAD-2). The PHQ-15 is equal or superior to other brief measures for assessing somatic symptoms and screening for somatoform disorders. Cutpoints of 5, 10 and 15 represent mild, moderate and severe symptom levels on all three scales. Sensitivity to change is well-established for the PHQ-9 and emerging albeit not yet definitive for the GAD-7 and PHQ-15. Conclusions The PHQ-9, GAD-7 and PHQ-15 are brief well-validated measures for detecting and monitoring depression, anxiety and somatization.
-
the Patient Health Questionnaire 2 validity of a two item depression screener
Medical Care, 2003Co-Authors: Kurt Kroenke, Robert L Spitzer, Janet B W WilliamsAbstract:Background. A number of self-administered Questionnaires are available for assessing depression severity, including the 9-item Patient Health Questionnaire depression module (PHQ-9). Because even briefer measures might be desirable for use in busy clinical settings or as part of comprehensive Health
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
-
Validity and utility of the PRIME-MD Patient Health Questionnaire in assessment of 3000 obstetric-gynecologic Patients: the PRIME-MD Patient Health Questionnaire Obstetrics-Gynecology Study.
American journal of obstetrics and gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, B. Kurt Kroenke, C. Raymond Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P
Julia Mcmurray - One of the best experts on this subject based on the ideXlab platform.
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
-
validity and utility of the prime md Patient Health Questionnaire in assessment of 3000 obstetric gynecologic Patients the prime md Patient Health Questionnaire obstetrics gynecology study
American Journal of Obstetrics and Gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, Kurt B Kroenke, Raymond C Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P <.005 for all measures). Although most clinicians judged the PRIME-MD PHQ to be useful in management decisions, the Questionnaire diagnosis of mental disorder rarely led to therapeutic intervention. CONCLUSION: The PRIME-MD PHQ is a useful instrument for the assessment of mental disorders, functional impairment, and recent psychosocial stressors in the busy obstetrics-gynecology setting.
-
Validity and utility of the PRIME-MD Patient Health Questionnaire in assessment of 3000 obstetric-gynecologic Patients: the PRIME-MD Patient Health Questionnaire Obstetrics-Gynecology Study.
American journal of obstetrics and gynecology, 2000Co-Authors: Robert L Spitzer, Janet B W Williams, B. Kurt Kroenke, C. Raymond Hornyak, Julia McmurrayAbstract:OBJECTIVE: This study was undertaken to determine the prevalence of mental disorders among obstetric-gynecologic Patients and to assess the validity and utility of the PRIME-MD Patient Health Questionnaire (PHQ) in this population. STUDY DESIGN: A total of 3000 Patients were assessed by 63 clinicians at seven obstetrics-gynecology outPatient care sites. The main outcome measures were PRIME-MD PHQ diagnoses, psychosocial stressors, independent diagnoses made by mental Health professionals, functional status measures, disability days, Health care use, and treatment or referral decisions. RESULTS: Current mental disorders were fairly prevalent, present in 1 in 5 obstetric-gynecologic Patients. Patients with PRIME-MD PHQ diagnoses had more functional impairment, disability days, Health care use, and psychosocial stressors than did Patients without PRIME-MD PHQ diagnoses (P
