The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Linda H Nie - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    BACKGROUND Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. OBJECTIVE We compared measurements from a portable XRF device and a KXRF device. METHODS We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38-95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. RESULTS The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness < 6 mm (72% of the sample). Bone Pb Concentrations were higher among participants who were older or were occupationally exposed to Pb. Soft tissue thickness decreased with age. CONCLUSION With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    Abstract Background Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. Objective We compared measurements from a portable XRF device and a KXRF device. Methods We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38–95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. Results The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness  Conclusion With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

Xinxin Zhang - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    BACKGROUND Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. OBJECTIVE We compared measurements from a portable XRF device and a KXRF device. METHODS We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38-95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. RESULTS The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness < 6 mm (72% of the sample). Bone Pb Concentrations were higher among participants who were older or were occupationally exposed to Pb. Soft tissue thickness decreased with age. CONCLUSION With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    Abstract Background Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. Objective We compared measurements from a portable XRF device and a KXRF device. Methods We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38–95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. Results The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness  Conclusion With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

M Reiffers - One of the best experts on this subject based on the ideXlab platform.

  • influence of Pb Concentration on microstructural and superconducting properties of bscco superconductors
    Superconductor Science and Technology, 1995
    Co-Authors: N Hudakova, V Plechacek, P Dordor, K Flachbart, K Knizek, Jozef Kovac, M Reiffers
    Abstract:

    The microstructure and superconducting properties of high-Tc superconducting materials Bi2-xPbxSr2Ca2Cu3O10+y with variable amounts of lead; (x=0.2, 0.3, 0.4 and 0.5) have been studied. Nearly single-phase samples were prepared for x=0.3, 0.4 and 0.5. There is some optimal Concentration of Pb around x=0.3 for which the electrical resistivity is minimal, the transport critical current density Jc is maximal and the magnetization decreases more quickly with decreasing temperature.

Aaron J Specht - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    BACKGROUND Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. OBJECTIVE We compared measurements from a portable XRF device and a KXRF device. METHODS We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38-95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. RESULTS The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness < 6 mm (72% of the sample). Bone Pb Concentrations were higher among participants who were older or were occupationally exposed to Pb. Soft tissue thickness decreased with age. CONCLUSION With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    Abstract Background Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. Objective We compared measurements from a portable XRF device and a KXRF device. Methods We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38–95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. Results The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness  Conclusion With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

Ellen M Wells - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    BACKGROUND Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. OBJECTIVE We compared measurements from a portable XRF device and a KXRF device. METHODS We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38-95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. RESULTS The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness < 6 mm (72% of the sample). Bone Pb Concentrations were higher among participants who were older or were occupationally exposed to Pb. Soft tissue thickness decreased with age. CONCLUSION With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.

  • evaluation of a portable xrf device for in vivo quantification of lead in bone among a us population
    Science of The Total Environment, 2021
    Co-Authors: Xinxin Zhang, Aaron J Specht, Ellen M Wells, Marc G Weisskopf, Jennifer Weuve, Linda H Nie
    Abstract:

    Abstract Background Lead (Pb) Concentration in bone is a reliable biomarker for cumulative Pb exposure and studying associated health outcomes. However, the standard K-shell fluorescence (KXRF) bone Pb measurement technology has limitations in large-scale population studies. Objective We compared measurements from a portable XRF device and a KXRF device. Methods We measured bone Pb Concentrations in vivo using portable XRF and KXRF, each measured at the mid-tibia bone in 71 people, 38–95 years of age (mean ± SD = 63 ± 11 years) living in or near three Indiana communities, US; 10 participants were occupationally exposed. We estimated the correlation between bone Pb Concentrations measured by both devices. We also examined the extent to which the detection limit (DL) of the portable XRF was influenced by scan time and overlying soft tissue thickness. Finally, we quantified the associations of estimated bone Pb Concentration with age and age with soft tissue thickness. Results The mean bone Pb Concentration measured via portable XRF was 12.3 ± 16.7 mg Pb/kg dry bone. The uncertainty of a 3-minute (N = 60) in vivo portable XRF measurement ranged from 1.8 to 6.3 mg/kg, in the context of soft tissue thickness ranging from 2 to 6 mm. This uncertainty was reduced by a factor of 1.4 with 5-minute measurements (N = 11). Bone Pb measurements via portable XRF and KXRF were significantly correlated: r = 0.48 for all participants, and r = 0.73 among participants with soft tissue thickness  Conclusion With its ease of use, portability, and comparable sensitivity with conventional KXRF systems, the portable XRF could be a valuable tool for non-invasive quantification of bone Pb in vivo, especially for people with thinner soft tissue.