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Holly E Richter - One of the best experts on this subject based on the ideXlab platform.

  • Physical performance measures in older women with urinary incontinence: Pelvic Floor Disorder or geriatric syndrome?
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Derik Davis, Chi Chiung Grace Chen, Soren Bentzen, Jack Guralnik, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0–36), Short Physical Performance Battery (SPPB; range 0–12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores < 32 and  0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

  • physical performance measures in older women with urinary incontinence Pelvic Floor Disorder or geriatric syndrome
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Chi Chiung Grace Chen, Jack Guralnik, Derik L Davis, Soren M Bentzen, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0-36), Short Physical Performance Battery (SPPB; range 0-12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores Results Women were 76.6 ± 4.7 years old with mean body mass index 33.5 ± 9.0 kg/m2. Mixed UI was the most prevalent (n = 17; 85%), and 14 (70%) participants rated their UI as moderate or severe. Low MPPT ( 0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

  • Pelvic Floor Disorder symptoms and bone strength in postmenopausal women
    International Urogynecology Journal, 2020
    Co-Authors: Isuzu Meyer, Sarah L Morgan, Alayne D Markland, Jeff M Szychowski, Holly E Richter
    Abstract:

    The current study is aimed at characterizing the association between Pelvic Floor Disorder symptoms and bone strength reflecting a potential connective tissue pathophysiology in postmenopausal women. A cross-sectional study was conducted in postmenopausal women undergoing osteoporosis evaluation from 2007 to 2010. Urinary incontinence (UI) was defined as urinary leakage ≥2–3 times/week. UI types were defined using the 3 Incontinence Questionnaire. Fecal incontinence was defined as stool leakage ≥1/month, and Pelvic organ prolapse as a positive response to “Do you have a bulge or something falling out that you can see or feel in your vaginal area?” Bone quality and quantity were assessed using the trabecular bone score (TBS) and bone mineral density respectively: bone strength was defined by combined quality/quantity index, low strength being equivalent to moderate to severe fracture risk; low quality as TBS ≤ 1.31; low quantity by T-score <−1 or on osteoporosis medication. Of 681 subjects, 262 had low bone strength whereas 419 were normal using the combined quality/quantity bone assessment. Characteristics were similar except for age (low bone strength: 69.0 ± 8.2 vs normal: 65.0 ± 7.1, p < 0.01) and smoking (8.8% vs 3.3%, p < 0.01). Low bone strength was associated with any UI (adjusted odds ratio [aOR]: 1.48, 1.05–2.10), stress (aOR: 1.53, 1.06–2.21), and mixed (aOR :1.45, 1.02–2.05). Women with low bone quality had increased odds of UI (any, urgency, mixed), whereas none of the Pelvic Floor Disorder symptoms was associated with low bone quantity. Low bone strength defined by a combined quantity/quality index, as well as low bone quality alone, were associated with increased risk of UI.

  • Pelvic Floor Disorder symptoms and bone strength in postmenopausal women
    International Urogynecology Journal, 2020
    Co-Authors: Isuzu Meyer, Sarah L Morgan, Alayne D Markland, Jeff M Szychowski, Holly E Richter
    Abstract:

    Introduction and hypothesis The current study is aimed at characterizing the association between Pelvic Floor Disorder symptoms and bone strength reflecting a potential connective tissue pathophysiology in postmenopausal women. Methods A cross-sectional study was conducted in postmenopausal women undergoing osteoporosis evaluation from 2007 to 2010. Urinary incontinence (UI) was defined as urinary leakage ≥2–3 times/week. UI types were defined using the 3 Incontinence Questionnaire. Fecal incontinence was defined as stool leakage ≥1/month, and Pelvic organ prolapse as a positive response to “Do you have a bulge or something falling out that you can see or feel in your vaginal area?” Bone quality and quantity were assessed using the trabecular bone score (TBS) and bone mineral density respectively: bone strength was defined by combined quality/quantity index, low strength being equivalent to moderate to severe fracture risk; low quality as TBS ≤ 1.31; low quantity by T-score 

  • vitamin d status in women with Pelvic Floor Disorder symptoms
    International Urogynecology Journal, 2012
    Co-Authors: Candace Y Parkerautry, Alayne D Markland, Alicia Ballard, Deidra Downsgunn, Holly E Richter
    Abstract:

    Introduction and hypothesis Our aim was to characterize the relationship between 25-hydroxyvitamin D [25(OH)D] status with Pelvic Floor symptom distress and impact on quality of life.

Alice S. Ryan - One of the best experts on this subject based on the ideXlab platform.

  • Physical performance measures in older women with urinary incontinence: Pelvic Floor Disorder or geriatric syndrome?
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Derik Davis, Chi Chiung Grace Chen, Soren Bentzen, Jack Guralnik, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0–36), Short Physical Performance Battery (SPPB; range 0–12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores < 32 and  0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

  • physical performance measures in older women with urinary incontinence Pelvic Floor Disorder or geriatric syndrome
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Chi Chiung Grace Chen, Jack Guralnik, Derik L Davis, Soren M Bentzen, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0-36), Short Physical Performance Battery (SPPB; range 0-12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores Results Women were 76.6 ± 4.7 years old with mean body mass index 33.5 ± 9.0 kg/m2. Mixed UI was the most prevalent (n = 17; 85%), and 14 (70%) participants rated their UI as moderate or severe. Low MPPT ( 0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

B Liedl - One of the best experts on this subject based on the ideXlab platform.

  • the impact of sacrospinous ligament fixation on pre existing nocturia and co existing Pelvic Floor dysfunction symptoms
    International Urogynecology Journal, 2020
    Co-Authors: Maren Himmler, Aidana Rakhimbayeva, Suzette E Sutherland, Janpaul W R Roovers, Alexander Yassouridis, B Liedl
    Abstract:

    To evaluate whether nocturia and coexisting Pelvic Floor symptoms in women with Pelvic organ prolapse (POP) can be improved by ligamentous fixation of apical vaginal prolapse to the sacrospinous ligament. We evaluated the PROPEL study data from 281 women with Pelvic organ prolapse stage > 2. Bothersome nocturia and coexisting Pelvic Floor symptoms were assessed with the Pelvic Floor Disorder Inventory (PFDI) questionnaire preoperatively and at 6, 12 and 24 months after successful vaginal prolapse repair. Women with successful reconstruction (POP-Q stage < 1 at all compartments throughout the 2-year follow-up), defined as anatomical “responders,” were compared to the anatomical “non-responders.” Among the patients completing all PFDI questions (N = 277), anatomical responders and non-responders were the groups of interest for our analysis. We found the occurrence rates of “moderate” or “quite a bit” of nocturia was significantly reduced after surgery in all subgroups (48.7% at baseline vs. 19.5% after 24 months). The occurrence of nocturia was halved for responders compared to non-responders (45.4% and 48.3% at baseline vs. 14% and 29.5% after 24 months). Anatomical non-responders still had a relevant improvement of POP-Q stages, especially in the apical compartment. Prevalence rates of co-existing over- and underactive bladder, fecal incontinence, defecation Disorders and pain symptoms were also significantly reduced postoperatively. Nocturia can be associated with symptomatic POP, with improvements seen following vaginal ligamentous prolapse repair. We caution providers, however, when advising patients of the possible resolution of nocturia following POP reconstruction, that all other traditional etiologies of nocturia must first be ruled out.

  • The impact of sacrospinous ligament fixation on pre-existing nocturia and co-existing Pelvic Floor dysfunction symptoms
    International Urogynecology Journal, 2020
    Co-Authors: Maren Himmler, Aidana Rakhimbayeva, Suzette E Sutherland, Janpaul W R Roovers, Alexander Yassouridis, B Liedl
    Abstract:

    Introduction and hypothesis To evaluate whether nocturia and coexisting Pelvic Floor symptoms in women with Pelvic organ prolapse (POP) can be improved by ligamentous fixation of apical vaginal prolapse to the sacrospinous ligament. Methods We evaluated the PROPEL study data from 281 women with Pelvic organ prolapse stage > 2. Bothersome nocturia and coexisting Pelvic Floor symptoms were assessed with the Pelvic Floor Disorder Inventory (PFDI) questionnaire preoperatively and at 6, 12 and 24 months after successful vaginal prolapse repair. Women with successful reconstruction (POP-Q stage < 1 at all compartments throughout the 2-year follow-up), defined as anatomical “responders,” were compared to the anatomical “non-responders.” Results Among the patients completing all PFDI questions ( N  = 277), anatomical responders and non-responders were the groups of interest for our analysis. We found the occurrence rates of “moderate” or “quite a bit” of nocturia was significantly reduced after surgery in all subgroups (48.7% at baseline vs. 19.5% after 24 months). The occurrence of nocturia was halved for responders compared to non-responders (45.4% and 48.3% at baseline vs. 14% and 29.5% after 24 months). Anatomical non-responders still had a relevant improvement of POP-Q stages, especially in the apical compartment. Prevalence rates of co-existing over- and underactive bladder, fecal incontinence, defecation Disorders and pain symptoms were also significantly reduced postoperatively. Conclusion Nocturia can be associated with symptomatic POP, with improvements seen following vaginal ligamentous prolapse repair. We caution providers, however, when advising patients of the possible resolution of nocturia following POP reconstruction, that all other traditional etiologies of nocturia must first be ruled out.

Tatiana V. D. Sanses - One of the best experts on this subject based on the ideXlab platform.

  • Physical performance measures in older women with urinary incontinence: Pelvic Floor Disorder or geriatric syndrome?
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Derik Davis, Chi Chiung Grace Chen, Soren Bentzen, Jack Guralnik, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0–36), Short Physical Performance Battery (SPPB; range 0–12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores < 32 and  0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

  • physical performance measures in older women with urinary incontinence Pelvic Floor Disorder or geriatric syndrome
    International Urogynecology Journal, 2020
    Co-Authors: Tatiana V. D. Sanses, Holly E Richter, Sharee Pearson, Chi Chiung Grace Chen, Jack Guralnik, Derik L Davis, Soren M Bentzen, Alice S. Ryan
    Abstract:

    Introduction and hypothesis To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI. Methods In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, Incontinence Impact Questionnaire [IIQ-7]) and functional status evaluation. Functional status evaluation included the Modified Physical Performance Test (MPPT; range 0-36), Short Physical Performance Battery (SPPB; range 0-12), and other physical performance measures (e.g., Timed Up and Go [TUG]). MPPT and SPPB scores Results Women were 76.6 ± 4.7 years old with mean body mass index 33.5 ± 9.0 kg/m2. Mixed UI was the most prevalent (n = 17; 85%), and 14 (70%) participants rated their UI as moderate or severe. Low MPPT ( 0.05) with UI measures. Conclusions Mobility and functional impairments are common among older women with UI. Associations between MPPT score and TUG performance with UI impact on quality of life suggest these physical performance measures could be markers of mobility and functional impairments in future research on UI in older women.

Maren Himmler - One of the best experts on this subject based on the ideXlab platform.

  • the impact of sacrospinous ligament fixation on pre existing nocturia and co existing Pelvic Floor dysfunction symptoms
    International Urogynecology Journal, 2020
    Co-Authors: Maren Himmler, Aidana Rakhimbayeva, Suzette E Sutherland, Janpaul W R Roovers, Alexander Yassouridis, B Liedl
    Abstract:

    To evaluate whether nocturia and coexisting Pelvic Floor symptoms in women with Pelvic organ prolapse (POP) can be improved by ligamentous fixation of apical vaginal prolapse to the sacrospinous ligament. We evaluated the PROPEL study data from 281 women with Pelvic organ prolapse stage > 2. Bothersome nocturia and coexisting Pelvic Floor symptoms were assessed with the Pelvic Floor Disorder Inventory (PFDI) questionnaire preoperatively and at 6, 12 and 24 months after successful vaginal prolapse repair. Women with successful reconstruction (POP-Q stage < 1 at all compartments throughout the 2-year follow-up), defined as anatomical “responders,” were compared to the anatomical “non-responders.” Among the patients completing all PFDI questions (N = 277), anatomical responders and non-responders were the groups of interest for our analysis. We found the occurrence rates of “moderate” or “quite a bit” of nocturia was significantly reduced after surgery in all subgroups (48.7% at baseline vs. 19.5% after 24 months). The occurrence of nocturia was halved for responders compared to non-responders (45.4% and 48.3% at baseline vs. 14% and 29.5% after 24 months). Anatomical non-responders still had a relevant improvement of POP-Q stages, especially in the apical compartment. Prevalence rates of co-existing over- and underactive bladder, fecal incontinence, defecation Disorders and pain symptoms were also significantly reduced postoperatively. Nocturia can be associated with symptomatic POP, with improvements seen following vaginal ligamentous prolapse repair. We caution providers, however, when advising patients of the possible resolution of nocturia following POP reconstruction, that all other traditional etiologies of nocturia must first be ruled out.

  • The impact of sacrospinous ligament fixation on pre-existing nocturia and co-existing Pelvic Floor dysfunction symptoms
    International Urogynecology Journal, 2020
    Co-Authors: Maren Himmler, Aidana Rakhimbayeva, Suzette E Sutherland, Janpaul W R Roovers, Alexander Yassouridis, B Liedl
    Abstract:

    Introduction and hypothesis To evaluate whether nocturia and coexisting Pelvic Floor symptoms in women with Pelvic organ prolapse (POP) can be improved by ligamentous fixation of apical vaginal prolapse to the sacrospinous ligament. Methods We evaluated the PROPEL study data from 281 women with Pelvic organ prolapse stage > 2. Bothersome nocturia and coexisting Pelvic Floor symptoms were assessed with the Pelvic Floor Disorder Inventory (PFDI) questionnaire preoperatively and at 6, 12 and 24 months after successful vaginal prolapse repair. Women with successful reconstruction (POP-Q stage < 1 at all compartments throughout the 2-year follow-up), defined as anatomical “responders,” were compared to the anatomical “non-responders.” Results Among the patients completing all PFDI questions ( N  = 277), anatomical responders and non-responders were the groups of interest for our analysis. We found the occurrence rates of “moderate” or “quite a bit” of nocturia was significantly reduced after surgery in all subgroups (48.7% at baseline vs. 19.5% after 24 months). The occurrence of nocturia was halved for responders compared to non-responders (45.4% and 48.3% at baseline vs. 14% and 29.5% after 24 months). Anatomical non-responders still had a relevant improvement of POP-Q stages, especially in the apical compartment. Prevalence rates of co-existing over- and underactive bladder, fecal incontinence, defecation Disorders and pain symptoms were also significantly reduced postoperatively. Conclusion Nocturia can be associated with symptomatic POP, with improvements seen following vaginal ligamentous prolapse repair. We caution providers, however, when advising patients of the possible resolution of nocturia following POP reconstruction, that all other traditional etiologies of nocturia must first be ruled out.