The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform
Elisabeth J Cohen - One of the best experts on this subject based on the ideXlab platform.
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wound dehiscence after Penetrating Keratoplasty
Cornea, 2006Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Christopher J Rapuano, Peter R Laibson, Elisabeth J CohenAbstract:Purpose:To assess the patient characteristics, risk factors, and outcomes of Penetrating Keratoplasty wound dehiscence.Methods:Retrospective chart review of 30 eyes of 29 patients with corneal grafts who underwent repair of Penetrating Keratoplasty wound dehiscence from January 1, 1998 to December 3
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Cataract Extraction Following Penetrating Keratoplasty
Cornea, 2004Co-Authors: Parveen K Nagra, Christopher J Rapuano, Peter R Laibson, D.y. Kunimoto, Elisabeth J CohenAbstract:OBJECTIVE: To assess the safety of cataract extraction following Penetrating Keratoplasty for corneal graft survival and to evaluate visual and refractive outcomes in corneal graft patients undergoing cataract extraction. METHODS: Retrospective chart review of 29 eyes of 24 patients with corneal grafts who underwent cataract extraction from January 1, 1993 to December 31, 2002, followed on the Cornea Service at Wills Eye Hospital. RESULTS: The mean time from Penetrating Keratoplasty to cataract extraction was 8.4 years (range 2 months to 36 years). Following cataract extraction, the corneal grafts remained clear in all but 1 eye (3%), during an average follow-up time of 44.5 months (range 3-118 months). All of the remaining patients benefited from improved visual acuity, with 15 of 28 patients having a postoperative best-corrected visual acuity of 20/30 or better. Patients also benefited from decreased absolute spherical refractive error, with a preoperative mean value of 6.6 +/- 3.4 D compared with 2.4 +/- 1.6 D postoperatively, while cylindrical refractive error remained relatively stable at 3.2 +/- 2.9 D preoperatively and 2.8 +/- 2.4 postoperatively. The patient who developed graft failure had 3 episodes of preoperative endothelial rejection and a clear corneal graft at the time of cataract surgery. CONCLUSIONS: Cataract surgery following Penetrating Keratoplasty is a safe and effective procedure, with a low but definite risk of corneal graft failure. In patients with clear grafts and visually significant cataracts, cataract extraction alone is preferred over repeat Penetrating Keratoplasty and cataract extraction.
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indications for Penetrating Keratoplasty and associated procedures 1996 2000
Cornea, 2002Co-Authors: Banu C Cosar, Christopher J Rapuano, Elisabeth J Cohen, Paulo De Tarso S. Alvim, M S Sridhar, Evan L Held, Irving M Raber, Peter R LaibsonAbstract:Purpose.To identify current indications and trends in indications for Penetrating Keratoplasty and associated procedures.Methods.Retrospective chart review of all patients who underwent Penetrating Keratoplasty at Wills Eye Hospital from January 1, 1996 to December 31, 2000.Results.A total of 1,529
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Penetrating Keratoplasty in iridocorneal endothelial syndrome.
Cornea, 2001Co-Authors: Paulo De Tarso S. Alvim, Christopher J Rapuano, Elisabeth J Cohen, Christine W. Chung, Mary Lucy M Pereira, Ralph C. Eagle, L. J. Katz, Andrew F Smith, Peter R LaibsonAbstract:Purpose.To evaluate the clinical outcome of Penetrating Keratoplasty (PK) in iridocorneal endothelial (ICE) syndrome.Methods.Clinical charts of patients who underwent Penetrating Keratoplasty for ICE syndrome between 1985 and 1999 were reviewed retrospectively. Glaucoma control, best corrected visua
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Penetrating Keratoplasty for varicella-zoster virus keratopathy.
Cornea, 2000Co-Authors: Marco Antonio G. Tanure, Christopher J Rapuano, Elisabeth J Cohen, Sanjeev Grewal, Peter R LaibsonAbstract:PURPOSE: To examine and report the results of Penetrating Keratoplasty performed in patients with varicella-zoster virus keratopathy. METHODS: The authors retrospectively reviewed the records of 15 patients who had Penetrating Keratoplasty for varicella-zoster virus keratopathy from January 1989 through December 1998 on the Cornea Service at Wills Eye Hospital. RESULTS: Twelve patients had a preoperative diagnosis of herpes zoster ophthalmicus, and three, of varicella. Four eyes had lateral tarsorrhaphies performed in conjunction with Penetrating Keratoplasty. Three eyes had endothelial rejection episodes that responded well to treatment with topical steroids. One eye had a regraft 1 month after primary failure, and this second graft also failed because of recurrent neurotrophic keratopathy. Three eyes that had repeated Penetrating Keratoplasty for graft failure had clear grafts at the last examination. At an average follow-up time of 50 months, 13 (86.7%) grafts remained clear, and the best corrected visual acuity was 20/100 or better in eight (53.3%) eyes. Five patients had decreased visual acuity because of retinal diseases. CONCLUSION: Although varicella-zoster virus keratopathy is an uncommon indication for Penetrating Keratoplasty, effective visual rehabilitation can be achieved in these patients. Careful postoperative management, frequent lubrication, and lateral tarsorrhaphies to protect the corneal surface are major factors in the successful outcome of these cases.
Peter R Laibson - One of the best experts on this subject based on the ideXlab platform.
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wound dehiscence after Penetrating Keratoplasty
Cornea, 2006Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Christopher J Rapuano, Peter R Laibson, Elisabeth J CohenAbstract:Purpose:To assess the patient characteristics, risk factors, and outcomes of Penetrating Keratoplasty wound dehiscence.Methods:Retrospective chart review of 30 eyes of 29 patients with corneal grafts who underwent repair of Penetrating Keratoplasty wound dehiscence from January 1, 1998 to December 3
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Cataract Extraction Following Penetrating Keratoplasty
Cornea, 2004Co-Authors: Parveen K Nagra, Christopher J Rapuano, Peter R Laibson, D.y. Kunimoto, Elisabeth J CohenAbstract:OBJECTIVE: To assess the safety of cataract extraction following Penetrating Keratoplasty for corneal graft survival and to evaluate visual and refractive outcomes in corneal graft patients undergoing cataract extraction. METHODS: Retrospective chart review of 29 eyes of 24 patients with corneal grafts who underwent cataract extraction from January 1, 1993 to December 31, 2002, followed on the Cornea Service at Wills Eye Hospital. RESULTS: The mean time from Penetrating Keratoplasty to cataract extraction was 8.4 years (range 2 months to 36 years). Following cataract extraction, the corneal grafts remained clear in all but 1 eye (3%), during an average follow-up time of 44.5 months (range 3-118 months). All of the remaining patients benefited from improved visual acuity, with 15 of 28 patients having a postoperative best-corrected visual acuity of 20/30 or better. Patients also benefited from decreased absolute spherical refractive error, with a preoperative mean value of 6.6 +/- 3.4 D compared with 2.4 +/- 1.6 D postoperatively, while cylindrical refractive error remained relatively stable at 3.2 +/- 2.9 D preoperatively and 2.8 +/- 2.4 postoperatively. The patient who developed graft failure had 3 episodes of preoperative endothelial rejection and a clear corneal graft at the time of cataract surgery. CONCLUSIONS: Cataract surgery following Penetrating Keratoplasty is a safe and effective procedure, with a low but definite risk of corneal graft failure. In patients with clear grafts and visually significant cataracts, cataract extraction alone is preferred over repeat Penetrating Keratoplasty and cataract extraction.
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indications for Penetrating Keratoplasty and associated procedures 1996 2000
Cornea, 2002Co-Authors: Banu C Cosar, Christopher J Rapuano, Elisabeth J Cohen, Paulo De Tarso S. Alvim, M S Sridhar, Evan L Held, Irving M Raber, Peter R LaibsonAbstract:Purpose.To identify current indications and trends in indications for Penetrating Keratoplasty and associated procedures.Methods.Retrospective chart review of all patients who underwent Penetrating Keratoplasty at Wills Eye Hospital from January 1, 1996 to December 31, 2000.Results.A total of 1,529
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Penetrating Keratoplasty in iridocorneal endothelial syndrome.
Cornea, 2001Co-Authors: Paulo De Tarso S. Alvim, Christopher J Rapuano, Elisabeth J Cohen, Christine W. Chung, Mary Lucy M Pereira, Ralph C. Eagle, L. J. Katz, Andrew F Smith, Peter R LaibsonAbstract:Purpose.To evaluate the clinical outcome of Penetrating Keratoplasty (PK) in iridocorneal endothelial (ICE) syndrome.Methods.Clinical charts of patients who underwent Penetrating Keratoplasty for ICE syndrome between 1985 and 1999 were reviewed retrospectively. Glaucoma control, best corrected visua
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Penetrating Keratoplasty for varicella-zoster virus keratopathy.
Cornea, 2000Co-Authors: Marco Antonio G. Tanure, Christopher J Rapuano, Elisabeth J Cohen, Sanjeev Grewal, Peter R LaibsonAbstract:PURPOSE: To examine and report the results of Penetrating Keratoplasty performed in patients with varicella-zoster virus keratopathy. METHODS: The authors retrospectively reviewed the records of 15 patients who had Penetrating Keratoplasty for varicella-zoster virus keratopathy from January 1989 through December 1998 on the Cornea Service at Wills Eye Hospital. RESULTS: Twelve patients had a preoperative diagnosis of herpes zoster ophthalmicus, and three, of varicella. Four eyes had lateral tarsorrhaphies performed in conjunction with Penetrating Keratoplasty. Three eyes had endothelial rejection episodes that responded well to treatment with topical steroids. One eye had a regraft 1 month after primary failure, and this second graft also failed because of recurrent neurotrophic keratopathy. Three eyes that had repeated Penetrating Keratoplasty for graft failure had clear grafts at the last examination. At an average follow-up time of 50 months, 13 (86.7%) grafts remained clear, and the best corrected visual acuity was 20/100 or better in eight (53.3%) eyes. Five patients had decreased visual acuity because of retinal diseases. CONCLUSION: Although varicella-zoster virus keratopathy is an uncommon indication for Penetrating Keratoplasty, effective visual rehabilitation can be achieved in these patients. Careful postoperative management, frequent lubrication, and lateral tarsorrhaphies to protect the corneal surface are major factors in the successful outcome of these cases.
Christopher J Rapuano - One of the best experts on this subject based on the ideXlab platform.
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survival of primary Penetrating Keratoplasty in children
American Journal of Ophthalmology, 2016Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Remzi Karadag, Tommy C Y Chan, Amir A Azari, Christopher J RapuanoAbstract:Purpose To review the indications and outcomes of children undergoing primary Penetrating Keratoplasty and identify prognostic factors for graft survival. Design Retrospective, interventional case series. Methods Medical records of every child 12 years of age or younger who underwent primary Penetrating Keratoplasty at Wills Eye Hospital Cornea Service between 2007 and 2015 were reviewed. Survival of the primary graft was analyzed using the Kaplan-Meier survival method. Results Forty-six eyes of 35 children underwent primary Keratoplasty during the study period. The mean age at the time of primary Keratoplasty was 24.6 ± 39.9 months. The mean follow-up duration was 36.4 ± 28.8 months. Congenital opacity was the most common diagnosis for primary Keratoplasty (89.1%). The overall mean graft survival time was 45.2 ± 5.8 months, with a survival rate of 75.7% at 1 year. The 1-year graft survival rate was 51.9% and 90.7% in eyes with and without glaucoma, respectively. Cox proportional hazards regression analysis demonstrated that the presence of glaucoma ( P = .014) and concurrent operation during primary Keratoplasty ( P = .049) were independent prognostic factors for poor graft survival. On the other hand, age of primary Keratoplasty ( P = .626) and operation before or after primary Keratoplasty ( P = .800 and P = .104, respectively) were not associated with poorer graft survival. Half of our patients were able to achieve ambulatory vision at the last follow-up. Conclusion Although pediatric Penetrating Keratoplasty is challenging, successful transplantation with good graft survival can be obtained. Better understanding of prognostic factors can possibly improve graft survival in the future.
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wound dehiscence after Penetrating Keratoplasty
Cornea, 2006Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Christopher J Rapuano, Peter R Laibson, Elisabeth J CohenAbstract:Purpose:To assess the patient characteristics, risk factors, and outcomes of Penetrating Keratoplasty wound dehiscence.Methods:Retrospective chart review of 30 eyes of 29 patients with corneal grafts who underwent repair of Penetrating Keratoplasty wound dehiscence from January 1, 1998 to December 3
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Cataract Extraction Following Penetrating Keratoplasty
Cornea, 2004Co-Authors: Parveen K Nagra, Christopher J Rapuano, Peter R Laibson, D.y. Kunimoto, Elisabeth J CohenAbstract:OBJECTIVE: To assess the safety of cataract extraction following Penetrating Keratoplasty for corneal graft survival and to evaluate visual and refractive outcomes in corneal graft patients undergoing cataract extraction. METHODS: Retrospective chart review of 29 eyes of 24 patients with corneal grafts who underwent cataract extraction from January 1, 1993 to December 31, 2002, followed on the Cornea Service at Wills Eye Hospital. RESULTS: The mean time from Penetrating Keratoplasty to cataract extraction was 8.4 years (range 2 months to 36 years). Following cataract extraction, the corneal grafts remained clear in all but 1 eye (3%), during an average follow-up time of 44.5 months (range 3-118 months). All of the remaining patients benefited from improved visual acuity, with 15 of 28 patients having a postoperative best-corrected visual acuity of 20/30 or better. Patients also benefited from decreased absolute spherical refractive error, with a preoperative mean value of 6.6 +/- 3.4 D compared with 2.4 +/- 1.6 D postoperatively, while cylindrical refractive error remained relatively stable at 3.2 +/- 2.9 D preoperatively and 2.8 +/- 2.4 postoperatively. The patient who developed graft failure had 3 episodes of preoperative endothelial rejection and a clear corneal graft at the time of cataract surgery. CONCLUSIONS: Cataract surgery following Penetrating Keratoplasty is a safe and effective procedure, with a low but definite risk of corneal graft failure. In patients with clear grafts and visually significant cataracts, cataract extraction alone is preferred over repeat Penetrating Keratoplasty and cataract extraction.
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indications for Penetrating Keratoplasty and associated procedures 1996 2000
Cornea, 2002Co-Authors: Banu C Cosar, Christopher J Rapuano, Elisabeth J Cohen, Paulo De Tarso S. Alvim, M S Sridhar, Evan L Held, Irving M Raber, Peter R LaibsonAbstract:Purpose.To identify current indications and trends in indications for Penetrating Keratoplasty and associated procedures.Methods.Retrospective chart review of all patients who underwent Penetrating Keratoplasty at Wills Eye Hospital from January 1, 1996 to December 31, 2000.Results.A total of 1,529
-
Penetrating Keratoplasty in iridocorneal endothelial syndrome.
Cornea, 2001Co-Authors: Paulo De Tarso S. Alvim, Christopher J Rapuano, Elisabeth J Cohen, Christine W. Chung, Mary Lucy M Pereira, Ralph C. Eagle, L. J. Katz, Andrew F Smith, Peter R LaibsonAbstract:Purpose.To evaluate the clinical outcome of Penetrating Keratoplasty (PK) in iridocorneal endothelial (ICE) syndrome.Methods.Clinical charts of patients who underwent Penetrating Keratoplasty for ICE syndrome between 1985 and 1999 were reviewed retrospectively. Glaucoma control, best corrected visua
Parveen K Nagra - One of the best experts on this subject based on the ideXlab platform.
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survival of primary Penetrating Keratoplasty in children
American Journal of Ophthalmology, 2016Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Remzi Karadag, Tommy C Y Chan, Amir A Azari, Christopher J RapuanoAbstract:Purpose To review the indications and outcomes of children undergoing primary Penetrating Keratoplasty and identify prognostic factors for graft survival. Design Retrospective, interventional case series. Methods Medical records of every child 12 years of age or younger who underwent primary Penetrating Keratoplasty at Wills Eye Hospital Cornea Service between 2007 and 2015 were reviewed. Survival of the primary graft was analyzed using the Kaplan-Meier survival method. Results Forty-six eyes of 35 children underwent primary Keratoplasty during the study period. The mean age at the time of primary Keratoplasty was 24.6 ± 39.9 months. The mean follow-up duration was 36.4 ± 28.8 months. Congenital opacity was the most common diagnosis for primary Keratoplasty (89.1%). The overall mean graft survival time was 45.2 ± 5.8 months, with a survival rate of 75.7% at 1 year. The 1-year graft survival rate was 51.9% and 90.7% in eyes with and without glaucoma, respectively. Cox proportional hazards regression analysis demonstrated that the presence of glaucoma ( P = .014) and concurrent operation during primary Keratoplasty ( P = .049) were independent prognostic factors for poor graft survival. On the other hand, age of primary Keratoplasty ( P = .626) and operation before or after primary Keratoplasty ( P = .800 and P = .104, respectively) were not associated with poorer graft survival. Half of our patients were able to achieve ambulatory vision at the last follow-up. Conclusion Although pediatric Penetrating Keratoplasty is challenging, successful transplantation with good graft survival can be obtained. Better understanding of prognostic factors can possibly improve graft survival in the future.
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wound dehiscence after Penetrating Keratoplasty
Cornea, 2006Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Christopher J Rapuano, Peter R Laibson, Elisabeth J CohenAbstract:Purpose:To assess the patient characteristics, risk factors, and outcomes of Penetrating Keratoplasty wound dehiscence.Methods:Retrospective chart review of 30 eyes of 29 patients with corneal grafts who underwent repair of Penetrating Keratoplasty wound dehiscence from January 1, 1998 to December 3
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Cataract Extraction Following Penetrating Keratoplasty
Cornea, 2004Co-Authors: Parveen K Nagra, Christopher J Rapuano, Peter R Laibson, D.y. Kunimoto, Elisabeth J CohenAbstract:OBJECTIVE: To assess the safety of cataract extraction following Penetrating Keratoplasty for corneal graft survival and to evaluate visual and refractive outcomes in corneal graft patients undergoing cataract extraction. METHODS: Retrospective chart review of 29 eyes of 24 patients with corneal grafts who underwent cataract extraction from January 1, 1993 to December 31, 2002, followed on the Cornea Service at Wills Eye Hospital. RESULTS: The mean time from Penetrating Keratoplasty to cataract extraction was 8.4 years (range 2 months to 36 years). Following cataract extraction, the corneal grafts remained clear in all but 1 eye (3%), during an average follow-up time of 44.5 months (range 3-118 months). All of the remaining patients benefited from improved visual acuity, with 15 of 28 patients having a postoperative best-corrected visual acuity of 20/30 or better. Patients also benefited from decreased absolute spherical refractive error, with a preoperative mean value of 6.6 +/- 3.4 D compared with 2.4 +/- 1.6 D postoperatively, while cylindrical refractive error remained relatively stable at 3.2 +/- 2.9 D preoperatively and 2.8 +/- 2.4 postoperatively. The patient who developed graft failure had 3 episodes of preoperative endothelial rejection and a clear corneal graft at the time of cataract surgery. CONCLUSIONS: Cataract surgery following Penetrating Keratoplasty is a safe and effective procedure, with a low but definite risk of corneal graft failure. In patients with clear grafts and visually significant cataracts, cataract extraction alone is preferred over repeat Penetrating Keratoplasty and cataract extraction.
Kristin M Hammersmith - One of the best experts on this subject based on the ideXlab platform.
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survival of primary Penetrating Keratoplasty in children
American Journal of Ophthalmology, 2016Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Remzi Karadag, Tommy C Y Chan, Amir A Azari, Christopher J RapuanoAbstract:Purpose To review the indications and outcomes of children undergoing primary Penetrating Keratoplasty and identify prognostic factors for graft survival. Design Retrospective, interventional case series. Methods Medical records of every child 12 years of age or younger who underwent primary Penetrating Keratoplasty at Wills Eye Hospital Cornea Service between 2007 and 2015 were reviewed. Survival of the primary graft was analyzed using the Kaplan-Meier survival method. Results Forty-six eyes of 35 children underwent primary Keratoplasty during the study period. The mean age at the time of primary Keratoplasty was 24.6 ± 39.9 months. The mean follow-up duration was 36.4 ± 28.8 months. Congenital opacity was the most common diagnosis for primary Keratoplasty (89.1%). The overall mean graft survival time was 45.2 ± 5.8 months, with a survival rate of 75.7% at 1 year. The 1-year graft survival rate was 51.9% and 90.7% in eyes with and without glaucoma, respectively. Cox proportional hazards regression analysis demonstrated that the presence of glaucoma ( P = .014) and concurrent operation during primary Keratoplasty ( P = .049) were independent prognostic factors for poor graft survival. On the other hand, age of primary Keratoplasty ( P = .626) and operation before or after primary Keratoplasty ( P = .800 and P = .104, respectively) were not associated with poorer graft survival. Half of our patients were able to achieve ambulatory vision at the last follow-up. Conclusion Although pediatric Penetrating Keratoplasty is challenging, successful transplantation with good graft survival can be obtained. Better understanding of prognostic factors can possibly improve graft survival in the future.
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wound dehiscence after Penetrating Keratoplasty
Cornea, 2006Co-Authors: Parveen K Nagra, Kristin M Hammersmith, Christopher J Rapuano, Peter R Laibson, Elisabeth J CohenAbstract:Purpose:To assess the patient characteristics, risk factors, and outcomes of Penetrating Keratoplasty wound dehiscence.Methods:Retrospective chart review of 30 eyes of 29 patients with corneal grafts who underwent repair of Penetrating Keratoplasty wound dehiscence from January 1, 1998 to December 3
