The Experts below are selected from a list of 2208 Experts worldwide ranked by ideXlab platform
Pojen Ko - One of the best experts on this subject based on the ideXlab platform.
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feasibility of transumbilical surgical lung biopsy and Pericardial Window creation
Surgical Innovation, 2014Co-Authors: Yicheng Wu, Mingju Hsieh, Tzuping Chen, Yingkai Chao, Chingyang Wu, Hsuchia Yuan, Pojen KoAbstract:Background. To date there are no practical platforms for performing natural orifice transluminal endoscopic surgery in the thoracic cavity. This study evaluates the feasibility of transumbilical thoracosopy for lung biopsy and Pericardial Window creation. Methods. Eleven dogs (6 in the nonsurvival group and 5 in the survival group) were used for this study. A homemade metallic tube was advanced into the abdominal cavity via a 12-mm umbilical incision. The metallic tube was advanced into the thoracic cavity through a subxyphoid diaphragmatic incision under video guidance. Access to the thoracic cavity was achieved by a flexible bronchoscope via the metallic tube. Surgical lung biopsy and Pericardial Window creation were performed using an electrocautery loop and needle knife. The animals were euthanized 20 minutes after the surgery was complete (nonsurvival group) or 14 days postsurgery (survival group) for necropsy evaluation. Results. Eight Pericardial Window creations and 21 of 22 preplanned lung biopsi...
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feasibility of endoscopic transoral thoracic surgical lung biopsy and Pericardial Window creation
Journal of Surgical Research, 2012Co-Authors: Pojen Ko, Yicheng Wu, Mingju Hsieh, Tzuping Chen, Chingyang Wu, Yinkai Chao, Hsuchia YuanAbstract:BACKGROUND: The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and Pericardial Window creation METHODS: Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a Pericardial Window creation were performed in 12 canines, using the transoral NOTES technique. RESULTS: The transoral endoscopic surgical lung biopsy and Pericardial Window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue. CONCLUSIONS: Transoral surgical lung biopsy and Pericardial Window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.
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natural orifice transluminal endoscopic surgery a transtracheal approach for the thoracic cavity in a live canine model
The Journal of Thoracic and Cardiovascular Surgery, 2011Co-Authors: Yicheng Wu, Huiwen Chang, Pojen KoAbstract:Background The present study aimed to evaluate the performance of transtracheal thoracic exploration and Pericardial Window creation in a canine survival model. Methods Transthoracic exploration was performed in 14 dogs. Under general anesthesia, after an incision in the right lateral wall of the middle–lower portion of the trachea was made, a 9-mm metal tube was advanced into the thoracic cavity. For thoracic cavity exploration and Pericardial Window creation, a flexible bronchoscope was introduced through the metal tube into the thoracic cavity. After thoracoscopy, a Dumon stent (Novatech, Grasse, France) was used to cover the tracheal incision site and facilitate healing. Animals were evaluated by endoscopy 1 and 2 weeks later. Animals were humanely killed, and necropsy was performed 2 weeks after the transtracheal natural orifice transluminal endoscopic surgery. Results Fourteen dogs underwent transtracheal thoracic exploration lasting for an average of 110 minutes (range, 80–150), with 3 perioperative deaths. At 2 weeks after Pericardial Window creation, endoscopy revealed normal healing of the tracheal incision sites in all 11 surviving animals. Necropsy on the 11 animals at 2 weeks showed 9 adhesions around the Pericardial Window and 5 adhesions around the tracheal incision region. No mediastinitis or abscesses could be identified. Conclusions Transtracheal thoracic exploration is technically feasible. Increasing surgical experience together with improvement in endoscopic techniques will further facilitate the development of natural orifice transluminal endoscopic surgery for thoracic diseases.
Yicheng Wu - One of the best experts on this subject based on the ideXlab platform.
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feasibility of transumbilical surgical lung biopsy and Pericardial Window creation
Surgical Innovation, 2014Co-Authors: Yicheng Wu, Mingju Hsieh, Tzuping Chen, Yingkai Chao, Chingyang Wu, Hsuchia Yuan, Pojen KoAbstract:Background. To date there are no practical platforms for performing natural orifice transluminal endoscopic surgery in the thoracic cavity. This study evaluates the feasibility of transumbilical thoracosopy for lung biopsy and Pericardial Window creation. Methods. Eleven dogs (6 in the nonsurvival group and 5 in the survival group) were used for this study. A homemade metallic tube was advanced into the abdominal cavity via a 12-mm umbilical incision. The metallic tube was advanced into the thoracic cavity through a subxyphoid diaphragmatic incision under video guidance. Access to the thoracic cavity was achieved by a flexible bronchoscope via the metallic tube. Surgical lung biopsy and Pericardial Window creation were performed using an electrocautery loop and needle knife. The animals were euthanized 20 minutes after the surgery was complete (nonsurvival group) or 14 days postsurgery (survival group) for necropsy evaluation. Results. Eight Pericardial Window creations and 21 of 22 preplanned lung biopsi...
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feasibility of endoscopic transoral thoracic surgical lung biopsy and Pericardial Window creation
Journal of Surgical Research, 2012Co-Authors: Pojen Ko, Yicheng Wu, Mingju Hsieh, Tzuping Chen, Chingyang Wu, Yinkai Chao, Hsuchia YuanAbstract:BACKGROUND: The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and Pericardial Window creation METHODS: Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a Pericardial Window creation were performed in 12 canines, using the transoral NOTES technique. RESULTS: The transoral endoscopic surgical lung biopsy and Pericardial Window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue. CONCLUSIONS: Transoral surgical lung biopsy and Pericardial Window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.
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natural orifice transluminal endoscopic surgery a transtracheal approach for the thoracic cavity in a live canine model
The Journal of Thoracic and Cardiovascular Surgery, 2011Co-Authors: Yicheng Wu, Huiwen Chang, Pojen KoAbstract:Background The present study aimed to evaluate the performance of transtracheal thoracic exploration and Pericardial Window creation in a canine survival model. Methods Transthoracic exploration was performed in 14 dogs. Under general anesthesia, after an incision in the right lateral wall of the middle–lower portion of the trachea was made, a 9-mm metal tube was advanced into the thoracic cavity. For thoracic cavity exploration and Pericardial Window creation, a flexible bronchoscope was introduced through the metal tube into the thoracic cavity. After thoracoscopy, a Dumon stent (Novatech, Grasse, France) was used to cover the tracheal incision site and facilitate healing. Animals were evaluated by endoscopy 1 and 2 weeks later. Animals were humanely killed, and necropsy was performed 2 weeks after the transtracheal natural orifice transluminal endoscopic surgery. Results Fourteen dogs underwent transtracheal thoracic exploration lasting for an average of 110 minutes (range, 80–150), with 3 perioperative deaths. At 2 weeks after Pericardial Window creation, endoscopy revealed normal healing of the tracheal incision sites in all 11 surviving animals. Necropsy on the 11 animals at 2 weeks showed 9 adhesions around the Pericardial Window and 5 adhesions around the tracheal incision region. No mediastinitis or abscesses could be identified. Conclusions Transtracheal thoracic exploration is technically feasible. Increasing surgical experience together with improvement in endoscopic techniques will further facilitate the development of natural orifice transluminal endoscopic surgery for thoracic diseases.
Hsuchia Yuan - One of the best experts on this subject based on the ideXlab platform.
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feasibility of transumbilical surgical lung biopsy and Pericardial Window creation
Surgical Innovation, 2014Co-Authors: Yicheng Wu, Mingju Hsieh, Tzuping Chen, Yingkai Chao, Chingyang Wu, Hsuchia Yuan, Pojen KoAbstract:Background. To date there are no practical platforms for performing natural orifice transluminal endoscopic surgery in the thoracic cavity. This study evaluates the feasibility of transumbilical thoracosopy for lung biopsy and Pericardial Window creation. Methods. Eleven dogs (6 in the nonsurvival group and 5 in the survival group) were used for this study. A homemade metallic tube was advanced into the abdominal cavity via a 12-mm umbilical incision. The metallic tube was advanced into the thoracic cavity through a subxyphoid diaphragmatic incision under video guidance. Access to the thoracic cavity was achieved by a flexible bronchoscope via the metallic tube. Surgical lung biopsy and Pericardial Window creation were performed using an electrocautery loop and needle knife. The animals were euthanized 20 minutes after the surgery was complete (nonsurvival group) or 14 days postsurgery (survival group) for necropsy evaluation. Results. Eight Pericardial Window creations and 21 of 22 preplanned lung biopsi...
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feasibility of endoscopic transoral thoracic surgical lung biopsy and Pericardial Window creation
Journal of Surgical Research, 2012Co-Authors: Pojen Ko, Yicheng Wu, Mingju Hsieh, Tzuping Chen, Chingyang Wu, Yinkai Chao, Hsuchia YuanAbstract:BACKGROUND: The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and Pericardial Window creation METHODS: Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a Pericardial Window creation were performed in 12 canines, using the transoral NOTES technique. RESULTS: The transoral endoscopic surgical lung biopsy and Pericardial Window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue. CONCLUSIONS: Transoral surgical lung biopsy and Pericardial Window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.
Tzuping Chen - One of the best experts on this subject based on the ideXlab platform.
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feasibility of transumbilical surgical lung biopsy and Pericardial Window creation
Surgical Innovation, 2014Co-Authors: Yicheng Wu, Mingju Hsieh, Tzuping Chen, Yingkai Chao, Chingyang Wu, Hsuchia Yuan, Pojen KoAbstract:Background. To date there are no practical platforms for performing natural orifice transluminal endoscopic surgery in the thoracic cavity. This study evaluates the feasibility of transumbilical thoracosopy for lung biopsy and Pericardial Window creation. Methods. Eleven dogs (6 in the nonsurvival group and 5 in the survival group) were used for this study. A homemade metallic tube was advanced into the abdominal cavity via a 12-mm umbilical incision. The metallic tube was advanced into the thoracic cavity through a subxyphoid diaphragmatic incision under video guidance. Access to the thoracic cavity was achieved by a flexible bronchoscope via the metallic tube. Surgical lung biopsy and Pericardial Window creation were performed using an electrocautery loop and needle knife. The animals were euthanized 20 minutes after the surgery was complete (nonsurvival group) or 14 days postsurgery (survival group) for necropsy evaluation. Results. Eight Pericardial Window creations and 21 of 22 preplanned lung biopsi...
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feasibility of endoscopic transoral thoracic surgical lung biopsy and Pericardial Window creation
Journal of Surgical Research, 2012Co-Authors: Pojen Ko, Yicheng Wu, Mingju Hsieh, Tzuping Chen, Chingyang Wu, Yinkai Chao, Hsuchia YuanAbstract:BACKGROUND: The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and Pericardial Window creation METHODS: Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a Pericardial Window creation were performed in 12 canines, using the transoral NOTES technique. RESULTS: The transoral endoscopic surgical lung biopsy and Pericardial Window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue. CONCLUSIONS: Transoral surgical lung biopsy and Pericardial Window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.
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Secure closure of the tracheal incision after natural orifice transluminal endoscopic surgery with a surgical sealant (CoSeal).
Surgical Innovation, 2011Co-Authors: Yun-hen Liu, Tzuping ChenAbstract:Background: To evaluate the effectiveness of surgical sealant (CoSeal) in sealing the tracheal assess sites after transtracheal thoracoscopy. Methods: Two dogs underwent transtracheal thoracic exploration and Pericardial Window creation. The thoracic cavity was approached with flexible bronchoscope through a 9-mm tracheal incision. The Pericardial Window was performed with a needle knife via the working channel of the bronchoscope, and the tracheal assess site was closed with CoSeal using a rubber catheter. The integrity of tracheal healing was evaluated under positive pressure ventilation. Result: Transtracheal creation of Pericardial Window and closure of tracheal incision with CoSeal was successfully performed in both dogs. There was no evidence of air leaks from the chest tube during positive pressure ventilation. Autopsy revealed no injury to the mediastinum and intrathoracic structure. Conclusion: Endoscopic closure of tracheal access site of NOTES with CoSeal appears to be a feasible technique.
Mingju Hsieh - One of the best experts on this subject based on the ideXlab platform.
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feasibility of transumbilical surgical lung biopsy and Pericardial Window creation
Surgical Innovation, 2014Co-Authors: Yicheng Wu, Mingju Hsieh, Tzuping Chen, Yingkai Chao, Chingyang Wu, Hsuchia Yuan, Pojen KoAbstract:Background. To date there are no practical platforms for performing natural orifice transluminal endoscopic surgery in the thoracic cavity. This study evaluates the feasibility of transumbilical thoracosopy for lung biopsy and Pericardial Window creation. Methods. Eleven dogs (6 in the nonsurvival group and 5 in the survival group) were used for this study. A homemade metallic tube was advanced into the abdominal cavity via a 12-mm umbilical incision. The metallic tube was advanced into the thoracic cavity through a subxyphoid diaphragmatic incision under video guidance. Access to the thoracic cavity was achieved by a flexible bronchoscope via the metallic tube. Surgical lung biopsy and Pericardial Window creation were performed using an electrocautery loop and needle knife. The animals were euthanized 20 minutes after the surgery was complete (nonsurvival group) or 14 days postsurgery (survival group) for necropsy evaluation. Results. Eight Pericardial Window creations and 21 of 22 preplanned lung biopsi...
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feasibility of endoscopic transoral thoracic surgical lung biopsy and Pericardial Window creation
Journal of Surgical Research, 2012Co-Authors: Pojen Ko, Yicheng Wu, Mingju Hsieh, Tzuping Chen, Chingyang Wu, Yinkai Chao, Hsuchia YuanAbstract:BACKGROUND: The thoracic cavity approach for natural orifice transluminal endoscopic surgery (NOTES) is technically challenging. The aim of this study was to evaluate the feasibility of a transoral endoscopic technique for a surgical lung biopsy and Pericardial Window creation METHODS: Under general anesthesia, a 12 mm incision was made over the vestibulum oris region. Under video guidance, a homemade metallic tube was introduced through the incision, extending along the pre-tracheal space to the substernal space with blunt dissection technique, and used as the entrance into the thoracic cavity. A surgical lung biopsy and a Pericardial Window creation were performed in 12 canines, using the transoral NOTES technique. RESULTS: The transoral endoscopic surgical lung biopsy and Pericardial Window creation were successfully completed in 11 of the 12 canines. Intraoperative bleeding and death from an injury to the pulmonary hilum developed in one animal during the electrosurgical excision of lung tissue. CONCLUSIONS: Transoral surgical lung biopsy and Pericardial Window creation in canine models is technically feasible and can be used as a novel experimental platform for studies of NOTES for intra-thoracic surgery.