The Experts below are selected from a list of 63 Experts worldwide ranked by ideXlab platform

Stefan Schultze-mosgau - One of the best experts on this subject based on the ideXlab platform.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation—a comparison between flapless and flap surgery in the mini-pig
    Clinical Oral Investigations, 2012
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study’s aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p  = 0.007; week 2, p  = 0.021; week 4, p  = 0.023; week 12, p  = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p  = 0.007; week 2, p  = 0.046; week 4, p  = 0.003; week 12, p  = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 ( p  = 0.027), 4 ( p  = 0.005) and 12 ( p  = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation--a comparison between flapless and flap surgery in the mini-pig.
    Clinical oral investigations, 2011
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study's aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p = 0.007; week 2, p = 0.021; week 4, p = 0.023; week 12, p = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p = 0.007; week 2, p = 0.046; week 4, p = 0.003; week 12, p = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 (p = 0.027), 4 (p = 0.005) and 12 (p = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

Cornelia K. Mueller - One of the best experts on this subject based on the ideXlab platform.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation—a comparison between flapless and flap surgery in the mini-pig
    Clinical Oral Investigations, 2012
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study’s aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p  = 0.007; week 2, p  = 0.021; week 4, p  = 0.023; week 12, p  = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p  = 0.007; week 2, p  = 0.046; week 4, p  = 0.003; week 12, p  = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 ( p  = 0.027), 4 ( p  = 0.005) and 12 ( p  = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation--a comparison between flapless and flap surgery in the mini-pig.
    Clinical oral investigations, 2011
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study's aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p = 0.007; week 2, p = 0.021; week 4, p = 0.023; week 12, p = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p = 0.007; week 2, p = 0.046; week 4, p = 0.003; week 12, p = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 (p = 0.027), 4 (p = 0.005) and 12 (p = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

Johannes K.m. Fakler - One of the best experts on this subject based on the ideXlab platform.

  • Silver-coated modular Megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss – a pilot study of 34 patients
    BMC Musculoskeletal Disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Background Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. Methods In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML München- Lübeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients’ histories, specifically the reInfection rates, the patients’ mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). Results The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p  = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1–72 months) in SCG and 8 months (1–48 months) in the NSCG ( p  = 0.61; α =0.05). The two groups showed no differences in the NMS. Conclusion With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.

  • Silver-coated modular Megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss – a pilot study of 34 patients
    BMC musculoskeletal disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML München- Lübeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients' histories, specifically the reInfection rates, the patients' mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1-72 months) in SCG and 8 months (1-48 months) in the NSCG (p = 0.61; α =0.05). The two groups showed no differences in the NMS. With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.

  • silver coated modular megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss a pilot study of 34 patients
    BMC Musculoskeletal Disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML Munchen- Lubeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients’ histories, specifically the reInfection rates, the patients’ mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1–72 months) in SCG and 8 months (1–48 months) in the NSCG (p = 0.61; α =0.05). The two groups showed no differences in the NMS. With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.

Michael Thorwarth - One of the best experts on this subject based on the ideXlab platform.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation—a comparison between flapless and flap surgery in the mini-pig
    Clinical Oral Investigations, 2012
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study’s aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p  = 0.007; week 2, p  = 0.021; week 4, p  = 0.023; week 12, p  = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p  = 0.007; week 2, p  = 0.046; week 4, p  = 0.003; week 12, p  = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 ( p  = 0.027), 4 ( p  = 0.005) and 12 ( p  = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

  • Analysis of inflammatory Periimplant lesions during a 12-week period of undisturbed plaque accumulation--a comparison between flapless and flap surgery in the mini-pig.
    Clinical oral investigations, 2011
    Co-Authors: Cornelia K. Mueller, Michael Thorwarth, Stefan Schultze-mosgau
    Abstract:

    This study's aim was to clarify the influence of soft tissue management on the development of Periimplant Infection. Four weeks after removal of all maxillary premolars in 12 mini-pigs, four BEGO Semados RI implants were inserted in each maxillary quadrant. Employing a split-mouth design, one quadrant was randomized to flapless insertion while the contralateral side was chosen for flap surgery. Following 1, 2, 4 and 12 weeks of transmucosal implant, healing biopsies were retrieved from the Periimplant soft tissue and subjected to further analysis. Histomorphometrically, a significant reduction of transmigration of polymorphonuclear neutrophils (week 1, p = 0.007; week 2, p = 0.021; week 4, p = 0.023; week 12, p = 0.013) as well as the density of the subepithelial inflammatory infiltrates (week 1, p = 0.007; week 2, p = 0.046; week 4, p = 0.003; week 12, p = 0.032) was verified following flapless surgery. Quantification of inducible nitric oxide synthase showed significantly reduced expression in the flapless group 2 (p = 0.027), 4 (p = 0.005) and 12 (p = 0.004) weeks post-insertion. Analysis of CD31 and collagen I immunostained sections revealed more regular capillary distribution as well as higher vessel and collagen density in the flapless group. The data of the present study indicate that flapless placement reduces the incidence of inflammatory Periimplant soft tissue lesions during a 12-week period. Considering the beneficial effects of flapless placement on early soft tissue healing and stability, the technique might be preferred in case of an uncomplicated locoregional anatomy with sufficient hard and soft tissue. However, this positive effect might disappear after manipulation of the implant and soft tissue during impression taking or try in of the prosthodontic supraconstruction.

Dirk Zajonz - One of the best experts on this subject based on the ideXlab platform.

  • Silver-coated modular Megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss – a pilot study of 34 patients
    BMC Musculoskeletal Disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Background Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. Methods In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML München- Lübeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients’ histories, specifically the reInfection rates, the patients’ mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). Results The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p  = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1–72 months) in SCG and 8 months (1–48 months) in the NSCG ( p  = 0.61; α =0.05). The two groups showed no differences in the NMS. Conclusion With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.

  • Silver-coated modular Megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss – a pilot study of 34 patients
    BMC musculoskeletal disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML München- Lübeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients' histories, specifically the reInfection rates, the patients' mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1-72 months) in SCG and 8 months (1-48 months) in the NSCG (p = 0.61; α =0.05). The two groups showed no differences in the NMS. With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.

  • silver coated modular megaendoprostheses in salvage revision arthroplasty after Periimplant Infection with extensive bone loss a pilot study of 34 patients
    BMC Musculoskeletal Disorders, 2017
    Co-Authors: Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth, Johannes K.m. Fakler
    Abstract:

    Hip and knee replacements in patients with bone defects after Infection correlates with high rates of reInfection. In this vulnerable patient population, the prevention of reInfection is to be considered superordinate to the functionality and defect bridging. The use of silver coating of aseptic implants as an Infection prophylaxis is already proven; however, the significance of these coatings in septic reimplantation of large implants is still not sufficiently investigated. In a retrospective analysis, 34 patients who have been treated with a modular mega-endoprosthesis after a cured bone Infection of the lower limb (femur or tibia) have been evaluated. One group with 14 patients (NSCG: non silver- coated group) was supplied with the non silver- coated implants: MML Munchen- Lubeck™ modular endoprosthesis system (AQ Implants, Ahrensburg, Germany) or MUTARS® Modular Universal Tumor And Revision System (Implantcast GmbH, Buxtehude, Germany). The other group with 20 patients (SCG: silver- coated group) was supplied with the silver- coated system of MUTARS®. In addition to the clinical findings and the patients’ histories, specifically the reInfection rates, the patients’ mobility was assessed using the New Mobility Score (NMS, by Parker and Palmer). The median follow-up period was 72 months, ranging from 6 to 267 months. The dropout rate was 5.8%. The reInfection rate after healed reInfection in SCG was 40% (8/20), in NSCG 57% (8/14), p = 0.34; α =0.05. The time for reInfection was, on average, 14 months (1–72 months) in SCG and 8 months (1–48 months) in the NSCG (p = 0.61; α =0.05). The two groups showed no differences in the NMS. With this retrospective analysis, it can be determined that the rate of reInfection of modular mega-endoprostheses on the hip and knee joint after healed periprosthetic joint Infection (PJI) can be reduced by the use of silver coated implants. The time until reInfection can also be delayed by utilizing silver coated implants. Due to the low number of cases of this highly specific patient population, no statistical significance could be determined. A positive effect, however, can be assumed through the use of silver coatings in mega-endoprostheses after an infectious situation.