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Alistair B Roberts - One of the best experts on this subject based on the ideXlab platform.

  • Perinatal Mortality in Type 2 diabetes mellitus.
    Diabetic Medicine, 2001
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P 

  • Perinatal Mortality in type 2 diabetes mellitus
    Diabetic Medicine, 2000
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P < 0.0001). Congenital malformations accounted for only 10% of the Perinatal Mortality. There was a seven-fold increase in the rate of late fetal death and 2.5-fold increase in the rates of intermediate fetal and late neonatal death. Subjects with Type 2 DM were significantly older and more obese than subjects with Type 1 DM, and presented later to the diabetes service. Conclusions Perinatal Mortality in Type 2 DM is significantly increased, mainly owing to an excess of late fetal death. Maternal factors such as obesity may be important contributors to the high Perinatal Mortality. Women diagnosed with GDM who have unrecognized Type 2 DM are also at high risk, but Perinatal Mortality is low in women with milder degrees of glucose intolerance in pregnancy.

Tim Cundy - One of the best experts on this subject based on the ideXlab platform.

  • Perinatal Mortality in Type 2 diabetes mellitus.
    Diabetic Medicine, 2001
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P 

  • Perinatal Mortality in type 2 diabetes mellitus
    Diabetic Medicine, 2000
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P < 0.0001). Congenital malformations accounted for only 10% of the Perinatal Mortality. There was a seven-fold increase in the rate of late fetal death and 2.5-fold increase in the rates of intermediate fetal and late neonatal death. Subjects with Type 2 DM were significantly older and more obese than subjects with Type 1 DM, and presented later to the diabetes service. Conclusions Perinatal Mortality in Type 2 DM is significantly increased, mainly owing to an excess of late fetal death. Maternal factors such as obesity may be important contributors to the high Perinatal Mortality. Women diagnosed with GDM who have unrecognized Type 2 DM are also at high risk, but Perinatal Mortality is low in women with milder degrees of glucose intolerance in pregnancy.

Marjo Metsaranta - One of the best experts on this subject based on the ideXlab platform.

  • decreasing Perinatal Mortality in placental abruption
    Acta Obstetricia et Gynecologica Scandinavica, 2013
    Co-Authors: Minna Tikkanen, Tiina Luukkaala, Mika Gissler, Annukka Ritvanen, Olavi Ylikorkala, Jorma Paavonen, Mika Nuutila, Sture Andersson, Marjo Metsaranta
    Abstract:

    Objective. To study Perinatal Mortality associated with placental abruption. Design. Retrospective population study using the Finnish Hospital Discharge Register and Medical Birth Register data. Setting. Finland, 1987–2005. Population. Pregnancies with placental abruption and all other births without placental abruption. Methods. The national Hospital Discharge Register and Medical Birth Register were used to identify all pregnancies with placental abruption. Demographic data and delivery outcomes were collected retrospectively. Perinatal Mortality associated with placental abruption was compared with that in other births. Potential risk factors were analysed. Main outcome measures. Perinatal Mortality in placental abruption. Results. The study consisted of 618 735 women with 1.14 million pregnancies, 4336 of whom had placental abruption. Overall Perinatal Mortality with abruption was 119 per 1000 births. Placental abruption explained 7% of all Perinatal deaths. The Mortality among singleton births (125 per 1000) was higher than among multiple births (40 per 1000). The majority of deaths (77%) occurred in utero. Singleton Perinatal Mortality with abruption decreased from 173 per 1000 in 1987–1990 to 98 per 1000 in 2000–2005 (p < 0.001). In singleton births at <32 gestational weeks, overall Perinatal Mortality was high (345 per 1000) and was not increased by placental abruption. Prematurity, low birthweight, male fetal sex and maternal smoking were independent risk factors for placental abruption-related Perinatal Mortality. Conclusions. Although Mortality associated with placental abruption decreased during the study period, placental abruption still remains an important cause of Perinatal Mortality.

  • Decreasing Perinatal Mortality in placental abruption
    Acta Obstetricia et Gynecologica Scandinavica, 2012
    Co-Authors: Minna Tikkanen, Tiina Luukkaala, Mika Gissler, Annukka Ritvanen, Olavi Ylikorkala, Jorma Paavonen, Mika Nuutila, Sture Andersson, Marjo Metsaranta
    Abstract:

    Objective. To study Perinatal Mortality associated with placental abruption. Design. Retrospective population study using the Finnish Hospital Discharge Register and Medical Birth Register data. Setting. Finland, 1987–2005. Population. Pregnancies with placental abruption and all other births without placental abruption. Methods. The national Hospital Discharge Register and Medical Birth Register were used to identify all pregnancies with placental abruption. Demographic data and delivery outcomes were collected retrospectively. Perinatal Mortality associated with placental abruption was compared with that in other births. Potential risk factors were analysed. Main outcome measures. Perinatal Mortality in placental abruption. Results. The study consisted of 618 735 women with 1.14 million pregnancies, 4336 of whom had placental abruption. Overall Perinatal Mortality with abruption was 119 per 1000 births. Placental abruption explained 7% of all Perinatal deaths. The Mortality among singleton births (125 per 1000) was higher than among multiple births (40 per 1000). The majority of deaths (77%) occurred in utero. Singleton Perinatal Mortality with abruption decreased from 173 per 1000 in 1987–1990 to 98 per 1000 in 2000–2005 (p < 0.001). In singleton births at

Greg D Gamble - One of the best experts on this subject based on the ideXlab platform.

  • Perinatal Mortality in Type 2 diabetes mellitus.
    Diabetic Medicine, 2001
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P 

  • Perinatal Mortality in type 2 diabetes mellitus
    Diabetic Medicine, 2000
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P < 0.0001). Congenital malformations accounted for only 10% of the Perinatal Mortality. There was a seven-fold increase in the rate of late fetal death and 2.5-fold increase in the rates of intermediate fetal and late neonatal death. Subjects with Type 2 DM were significantly older and more obese than subjects with Type 1 DM, and presented later to the diabetes service. Conclusions Perinatal Mortality in Type 2 DM is significantly increased, mainly owing to an excess of late fetal death. Maternal factors such as obesity may be important contributors to the high Perinatal Mortality. Women diagnosed with GDM who have unrecognized Type 2 DM are also at high risk, but Perinatal Mortality is low in women with milder degrees of glucose intolerance in pregnancy.

P Macpherson - One of the best experts on this subject based on the ideXlab platform.

  • Perinatal Mortality in Type 2 diabetes mellitus.
    Diabetic Medicine, 2001
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P 

  • Perinatal Mortality in type 2 diabetes mellitus
    Diabetic Medicine, 2000
    Co-Authors: Tim Cundy, Greg D Gamble, Kevin Townend, Patrick Henley, P Macpherson, Alistair B Roberts
    Abstract:

    Summary Aims In many parts of the world the number of pregnancies in women with Type 2 diabetes mellitus (DM) now exceeds that in women with Type 1 DM, but there are few data published on Perinatal Mortality in Type 2 DM. This study reports observational data on Perinatal Mortality in Type 2 DM from a population with a high background rate of this disorder. Methods Over a 12-year period (1985–1997) at the Diabetes Clinic at National Women’s Hospital, Auckland, there were 434 pregnancies in women with Type 2 DM (256 known and 178 diagnosed with gestational diabetes mellitus (GDM), but confirmed to have Type 2 DM early post-partum), 160 pregnancies in women with Type 1 DM and 932 in women with GDM. Perinatal Mortality was classified as either intermediate fetal death (20–28 weeks’ gestation), late fetal death (28 weeks’ gestation to term) or early neonatal death (up to 1 month post-partum). Results The Perinatal Mortality in Type 2 DM was 46.1/1000, significantly higher than the rates for the general population (12.5), Type 1 DM (12.5) and GDM (8.9) (P < 0.0001). Congenital malformations accounted for only 10% of the Perinatal Mortality. There was a seven-fold increase in the rate of late fetal death and 2.5-fold increase in the rates of intermediate fetal and late neonatal death. Subjects with Type 2 DM were significantly older and more obese than subjects with Type 1 DM, and presented later to the diabetes service. Conclusions Perinatal Mortality in Type 2 DM is significantly increased, mainly owing to an excess of late fetal death. Maternal factors such as obesity may be important contributors to the high Perinatal Mortality. Women diagnosed with GDM who have unrecognized Type 2 DM are also at high risk, but Perinatal Mortality is low in women with milder degrees of glucose intolerance in pregnancy.