Perinatal Period

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Benicio N Frey - One of the best experts on this subject based on the ideXlab platform.

  • sleep biological rhythms and anxiety in the Perinatal Period a systematic review protocol
    BMJ Open, 2021
    Co-Authors: Jasmyn E A Cunningham, Benicio N Frey, Aljeena R Qureshi, Sheryl M Green, Anastasiya Slyepchenko
    Abstract:

    Introduction Pregnancy and new parenthood is an exciting time, but also a stressful life event that can predispose to mental health challenges. Perinatal anxiety is one such challenge, and is an important contributor to parental distress and other negative outcomes. Sleep and biological rhythms are often disrupted in the Perinatal Period. These disruptions have been associated with postpartum depression, and in some cases with Perinatal anxiety. However, the literature concerning the association with Perinatal anxiety is inconsistent and may be methodologically limited. To our knowledge, there has been no comprehensive review published characterising the relationships between sleep, biological rhythms, and Perinatal anxiety and related disorders to date. In this systematic review, we will summarise the current state of the literature concerning these relationships, allowing us to highlight gaps and potentially inform clinical understanding of Perinatal anxiety, sleep and biological rhythms. Methods and analysis Primary research articles will be eligible for inclusion if they assess Perinatal anxiety or related disorders using validated criteria (self-report or diagnostic), assess sleep and biological rhythms in the Perinatal Period, include >4 participants and meet other inclusion/exclusion criteria. We will conduct comprehensive searches of MEDLINE, PsycINFO, Embase and CINAHL, with coverage spanning from database conception to search date (August 1, 2021). Key search concepts include (1) the Perinatal Period, (2) sleep/biological rhythms and (3) anxiety. Risk of bias will be evaluated using the Cochrane Risk of Bias Tool. Data will be narratively synthesised, with quantitative synthesis included if possible. When relevant, strength of evidence will be assessed using Grading of Recommendations Assessment, Development and Evaluation criteria, and potential publication bias will be assessed. Ethics and dissemination Research ethics approval is not required. Study results will be reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results will be disseminated to relevant stakeholders as conference presentation(s) and submitted for publication in a peer-reviewed journal. PROSPERO registration number 200166.

  • cognitive behavior therapy for women with generalized anxiety disorder in the Perinatal Period impact on problematic behaviors
    Behavior Therapy, 2021
    Co-Authors: Sheryl M Green, Melissa Furtado, Eleanor Donegan, Randi E Mccabe, David L Streiner, Laura Noble, Arela Agako, Benicio N Frey
    Abstract:

    Abstract Generalized anxiety disorder (GAD) is the most frequently diagnosed anxiety disorder among women in the Perinatal Period (pregnancy to one year postpartum). Recent studies have examined the relationship between problematic behaviors and GAD symptoms. Studies in nonPerinatal samples indicate that adults with GAD engage in avoidance and safety behaviors and these behaviors are associated with greater symptom severity. Little research has examined the use of problematic behaviors among pregnant or postpartum women. However, preliminary research suggests that these behaviors may have a negative impact on both anxious women and their children. Our aim was to examine the extent to which women with GAD in pregnancy or the postpartum engage in problematic behaviors and whether cognitive behavioral therapy is effective in reducing these behaviors. Fifty-eight women with GAD in pregnancy or postpartum were recruited from a larger clinical trial (Clinicaltrials.gov ID NCT02850523) evaluating the effectiveness of group-based cognitive behavioral therapy (CBGT) for Perinatal anxiety disorders. The results indicated that women with Perinatal GAD reported high levels of avoidance and safety behaviors and greater engagement in these behaviors was associated with higher levels of worry and related symptoms. CBGT was effective in reducing GAD symptoms and problematic behaviors and a bidirectional relationship was found between changes in worry and problematic behaviors during treatment. Limitations and future directions are discussed.

  • risk factors of new onset anxiety and anxiety exacerbation in the Perinatal Period a systematic review and meta analysis
    Journal of Affective Disorders, 2018
    Co-Authors: Melissa Furtado, Benicio N Frey, Cheryl H T Chow, Sawayra Owais, Ryan J Van Lieshout
    Abstract:

    Abstract Background Even though more than 20% of women meet diagnostic criteria for an anxiety disorder during the Perinatal Period, very little is known about the predictors of these problems. As a result, we systematically reviewed the literature on risk factors for new onset anxiety and maternal anxiety exacerbation in the Perinatal Period. Methods PubMed, MEDLINE, PsycINFO, CINAHL, Ovid, ProQuest Portal, and Web of Science were searched for studies assessing risk factors for the development of new onset anxiety or anxiety worsening in women during pregnancy and the postpartum Period. Results 11,759 citations were identified, with 11 studies meeting eligibility criteria. New onset anxiety was assessed in 7 studies, anxiety worsening in 3, and 1 assessed both. Lower educational attainment, living with extended family members, multiparity, a family history of psychiatric disorders, hyperemesis gravidarum, comorbid sleep disorders, and prenatal oxytocin exposure were risk factors for new onset Perinatal anxiety, while presence of comorbid psychiatric disorders and prenatal oxytocin were risk factors for anxiety worsening. Limitations Studies not explicitly stating whether participants had pre-existing anxiety disorders were excluded. As a result, meta-analysis was not possible for several risk factors. Conclusions Risk factors for new onset anxiety and anxiety worsening during the Perinatal Period include psychological, social, and biological exposures. Given the lack of studies differentiating women with and without pre-existing anxiety disorders, additional research is required in order to determine whether these factors differ from the non-puerperal population, as well as from each other.

  • do changes in subjective sleep and biological rhythms predict worsening in postpartum depressive symptoms a prospective study across the Perinatal Period
    Archives of Womens Mental Health, 2016
    Co-Authors: Maria Paz Loayza Hidalgo, Benicio N Frey, Elizabeth M Krawczak, Luciano Minuzzi
    Abstract:

    Abnormalities of sleep and biological rhythms have been widely implicated in the pathophysiology of major depressive disorder (MDD) and bipolar disorder (BD). However, less is known about the influence of biological rhythm disruptions across the Perinatal Period on postpartum depression (PPD). The objective of this study was to prospectively evaluate the relationship between subjective changes in both sleep and biological rhythms and worsening of depressive symptoms from pregnancy to the postpartum Period in women with and without mood disorders. Eighty-three participants (38 euthymic women with a history of a mood disorder and 45 healthy controls) were studied. Participants completed subjective assessments of sleep (Pittsburgh Sleep Quality Index), biological rhythm disturbances (Biological Rhythms Interview of Assessment in Neuropsychiatry), and depressive symptoms (Edinburgh Postnatal Depression Scale) prospectively at two time points: third trimester of pregnancy and at 6–12 weeks postpartum. Multivariate regression analyses showed that changes in biological rhythms across the Perinatal Period predicted worsening of depressive symptoms in both groups. Moreover, women with a history of a mood disorder showed higher levels of sleep and biological rhythm disruption during both pregnancy and the postpartum Period. These findings suggest that disruptions in biological rhythms during the Perinatal Period increase the risk for postpartum mood worsening in healthy pregnant as well as in pregnant women with a history of mood disorders.

Clara Strauss - One of the best experts on this subject based on the ideXlab platform.

  • the effectiveness of mindfulness based interventions in the Perinatal Period a systematic review and meta analysis
    PLOS ONE, 2016
    Co-Authors: Billie Lever Taylor, Kate Cavanagh, Clara Strauss
    Abstract:

    Perinatal mental health difficulties are associated with adverse consequences for parents and infants. However, the potential risks associated with the use of psychotropic medication for pregnant and breastfeeding women and the preferences expressed by women for non-pharmacological interventions mean it is important to ensure that effective psychological interventions are available. It has been argued that mindfulness-based interventions may offer a novel approach to treating Perinatal mental health difficulties, but relatively little is known about their effectiveness with Perinatal populations. This paper therefore presents a systematic review and meta-analysis of the effectiveness of mindfulness-based interventions for reducing depression, anxiety and stress and improving mindfulness skills in the Perinatal Period. A systematic review identified seventeen studies of mindfulness-based interventions in the Perinatal Period, including both controlled trials (n = 9) and pre-post uncontrolled studies (n = 8). Eight of these studies also included qualitative data. Hedge’s g was used to assess uncontrolled and controlled effect sizes in separate meta-analyses, and a narrative synthesis of qualitative data was produced. Pre- to post-analyses showed significant reductions in depression, anxiety and stress and significant increases in mindfulness skills post intervention, each with small to medium effect sizes. Completion of the mindfulness-based interventions was reasonable with around three quarters of participants meeting study-defined criteria for engagement or completion where this was recorded. Qualitative data suggested that participants viewed mindfulness interventions positively. However, between-group analyses failed to find any significant post-intervention benefits for depression, anxiety or stress of mindfulness-based interventions in comparison to control conditions: effect sizes were negligible and it was conspicuous that intervention group participants did not appear to improve significantly more than controls in their mindfulness skills. The interventions offered often deviated from traditional mindfulness-based cognitive therapy or mindfulness-based stress reduction programmes, and there was also a tendency for studies to focus on healthy rather than clinical populations, and on antenatal rather than postnatal populations. It is argued that these and other limitations with the included studies and their interventions may have been partly responsible for the lack of significant between-group effects. The implications of the findings and recommendations for future research are discussed.

Sheryl M Green - One of the best experts on this subject based on the ideXlab platform.

  • sleep biological rhythms and anxiety in the Perinatal Period a systematic review protocol
    BMJ Open, 2021
    Co-Authors: Jasmyn E A Cunningham, Benicio N Frey, Aljeena R Qureshi, Sheryl M Green, Anastasiya Slyepchenko
    Abstract:

    Introduction Pregnancy and new parenthood is an exciting time, but also a stressful life event that can predispose to mental health challenges. Perinatal anxiety is one such challenge, and is an important contributor to parental distress and other negative outcomes. Sleep and biological rhythms are often disrupted in the Perinatal Period. These disruptions have been associated with postpartum depression, and in some cases with Perinatal anxiety. However, the literature concerning the association with Perinatal anxiety is inconsistent and may be methodologically limited. To our knowledge, there has been no comprehensive review published characterising the relationships between sleep, biological rhythms, and Perinatal anxiety and related disorders to date. In this systematic review, we will summarise the current state of the literature concerning these relationships, allowing us to highlight gaps and potentially inform clinical understanding of Perinatal anxiety, sleep and biological rhythms. Methods and analysis Primary research articles will be eligible for inclusion if they assess Perinatal anxiety or related disorders using validated criteria (self-report or diagnostic), assess sleep and biological rhythms in the Perinatal Period, include >4 participants and meet other inclusion/exclusion criteria. We will conduct comprehensive searches of MEDLINE, PsycINFO, Embase and CINAHL, with coverage spanning from database conception to search date (August 1, 2021). Key search concepts include (1) the Perinatal Period, (2) sleep/biological rhythms and (3) anxiety. Risk of bias will be evaluated using the Cochrane Risk of Bias Tool. Data will be narratively synthesised, with quantitative synthesis included if possible. When relevant, strength of evidence will be assessed using Grading of Recommendations Assessment, Development and Evaluation criteria, and potential publication bias will be assessed. Ethics and dissemination Research ethics approval is not required. Study results will be reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results will be disseminated to relevant stakeholders as conference presentation(s) and submitted for publication in a peer-reviewed journal. PROSPERO registration number 200166.

  • cognitive behavior therapy for women with generalized anxiety disorder in the Perinatal Period impact on problematic behaviors
    Behavior Therapy, 2021
    Co-Authors: Sheryl M Green, Melissa Furtado, Eleanor Donegan, Randi E Mccabe, David L Streiner, Laura Noble, Arela Agako, Benicio N Frey
    Abstract:

    Abstract Generalized anxiety disorder (GAD) is the most frequently diagnosed anxiety disorder among women in the Perinatal Period (pregnancy to one year postpartum). Recent studies have examined the relationship between problematic behaviors and GAD symptoms. Studies in nonPerinatal samples indicate that adults with GAD engage in avoidance and safety behaviors and these behaviors are associated with greater symptom severity. Little research has examined the use of problematic behaviors among pregnant or postpartum women. However, preliminary research suggests that these behaviors may have a negative impact on both anxious women and their children. Our aim was to examine the extent to which women with GAD in pregnancy or the postpartum engage in problematic behaviors and whether cognitive behavioral therapy is effective in reducing these behaviors. Fifty-eight women with GAD in pregnancy or postpartum were recruited from a larger clinical trial (Clinicaltrials.gov ID NCT02850523) evaluating the effectiveness of group-based cognitive behavioral therapy (CBGT) for Perinatal anxiety disorders. The results indicated that women with Perinatal GAD reported high levels of avoidance and safety behaviors and greater engagement in these behaviors was associated with higher levels of worry and related symptoms. CBGT was effective in reducing GAD symptoms and problematic behaviors and a bidirectional relationship was found between changes in worry and problematic behaviors during treatment. Limitations and future directions are discussed.

Gerald F Giesbrecht - One of the best experts on this subject based on the ideXlab platform.

  • trajectories of sleep quality and associations with mood during the Perinatal Period
    Sleep, 2015
    Co-Authors: Lianne M Tomfohr, Elena Buliga, Nicole Letourneau, Tavis S Campbell, Gerald F Giesbrecht
    Abstract:

    OBJECTIVE The aim of this study was to investigate trajectories of sleep quality and associations with mood in the Perinatal Period. Although it is commonly accepted that subjective sleep quality declines during pregnancy and the transition to parenthood, some women may follow qualitatively distinct trajectories. DESIGN, SETTING, AND PARTICIPANTS Sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI). Data were collected from 293 women at four time points: during early pregnancy, at Time 1 (T1; < 22 w gestational age [GA]; late pregnancy, at Time 2 (T2; 32 w GA); during the postnatal Period at Time 3 (T3; 3 mo postpartum); and Time 4 (T4; 6 mo postpartum). A group-based semiparametric mixture model was used to estimate patterns of sleep quality throughout the Perinatal Period. RESULTS Four trajectory groups were identified, including patterns defined by high sleep quality throughout (21.5%), mild decrease in sleep quality (59.5%), significant decrease in sleep quality (12.3%) and a group with poor sleep quality throughout (6.7%). Women who had the worst sleep quality at Time 1 and those who experienced significant increases in sleep problems throughout pregnancy were also the groups who reported the highest levels of anxiety and depressive symptoms in early pregnancy and the lowest levels of social support. After controlling for covariates, the groups with worst subjective sleep quality during pregnancy were also the most likely to experience high symptoms of depression in the postpartum Period. CONCLUSIONS Most of the women in our sample reported mild sleep disturbances through the Perinatal Period. A subgroup of women reported a significant decline in sleep quality from early to late pregnancy and another reported poor subjective sleep quality throughout pregnancy; these groups had the greatest risk of experiencing high symptoms of depression in the postpartum Period.

Elizabeth M Krawczak - One of the best experts on this subject based on the ideXlab platform.

  • do changes in subjective sleep and biological rhythms predict worsening in postpartum depressive symptoms a prospective study across the Perinatal Period
    Archives of Womens Mental Health, 2016
    Co-Authors: Maria Paz Loayza Hidalgo, Benicio N Frey, Elizabeth M Krawczak, Luciano Minuzzi
    Abstract:

    Abnormalities of sleep and biological rhythms have been widely implicated in the pathophysiology of major depressive disorder (MDD) and bipolar disorder (BD). However, less is known about the influence of biological rhythm disruptions across the Perinatal Period on postpartum depression (PPD). The objective of this study was to prospectively evaluate the relationship between subjective changes in both sleep and biological rhythms and worsening of depressive symptoms from pregnancy to the postpartum Period in women with and without mood disorders. Eighty-three participants (38 euthymic women with a history of a mood disorder and 45 healthy controls) were studied. Participants completed subjective assessments of sleep (Pittsburgh Sleep Quality Index), biological rhythm disturbances (Biological Rhythms Interview of Assessment in Neuropsychiatry), and depressive symptoms (Edinburgh Postnatal Depression Scale) prospectively at two time points: third trimester of pregnancy and at 6–12 weeks postpartum. Multivariate regression analyses showed that changes in biological rhythms across the Perinatal Period predicted worsening of depressive symptoms in both groups. Moreover, women with a history of a mood disorder showed higher levels of sleep and biological rhythm disruption during both pregnancy and the postpartum Period. These findings suggest that disruptions in biological rhythms during the Perinatal Period increase the risk for postpartum mood worsening in healthy pregnant as well as in pregnant women with a history of mood disorders.