The Experts below are selected from a list of 12 Experts worldwide ranked by ideXlab platform
Klop K.w.j. - One of the best experts on this subject based on the ideXlab platform.
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Tailor-Made Live Kidney Donation
2014Co-Authors: Klop K.w.j.Abstract:__Abstract__ This thesis describes several aspects of live kidney donation, such as surgical techniques, cost-effectivity, cosmetics en quality of life. Kidney transplantation offer several benefits when compared to dialysis. These benefits include better recipient and graft survival, better access to transplantation and pre-emptive transplantation. Eligibility criteria for live kidney donation have been extended in the last decade, leading to an increase in live donors and an increase in donors with mild comorbidities. This development requires continuous innovation evaluation of all aspects of live kidney donation, including selection, Peroperative Care, surgical techniques, outcome and long-term survival. There is high quality evidence suggesting that laparoscopic donor nephrectomy is to be preferred over open donor nephrectomy. This thesis describes two randomized controlled trials comparing hand-assisted retroperitoneoscopic donor nephrectomy with full laparoscopic donor nephrectomy. Furthermore, we assess the learning curves o
Klop Karel - One of the best experts on this subject based on the ideXlab platform.
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Tailor-Made Live Kidney Donation
Erasmus University Rotterdam, 2014Co-Authors: Klop KarelAbstract:markdownabstract__Abstract__ This thesis describes several aspects of live kidney donation, such as surgical techniques, cost-effectivity, cosmetics en quality of life. Kidney transplantation offer several benefits when compared to dialysis. These benefits include better recipient and graft survival, better access to transplantation and pre-emptive transplantation. Eligibility criteria for live kidney donation have been extended in the last decade, leading to an increase in live donors and an increase in donors with mild comorbidities. This development requires continuous innovation evaluation of all aspects of live kidney donation, including selection, Peroperative Care, surgical techniques, outcome and long-term survival. There is high quality evidence suggesting that laparoscopic donor nephrectomy is to be preferred over open donor nephrectomy. This thesis describes two randomized controlled trials comparing hand-assisted retroperitoneoscopic donor nephrectomy with full laparoscopic donor nephrectomy. Furthermore, we assess the learning curves of both these techniques in a center with no experience and a center with abundant experience in endoscopic donor nephrectomy. The second part of the thesis focuses on post-operative outcome. It demonstrates the excellent cosmetic outcome after the procedure. Also, no difference in costs or cost-effectiveness was found between both earlier mentioned techniques. Quality of life after live donor nephrectomy is excellent. Furthermore, elderly donors tend to have higher quality of life scores after donation, and they also return to their baseline values earlier. Also, we try to identify factors that influence postoperative quality of life. In the final part we describe the ten-year follow-up on quality of life. The protocol of the LOVE-study is also presented. This study aims to assess the functional donor outcome on the long-term
Lange F - One of the best experts on this subject based on the ideXlab platform.
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Clinical Brain Monitoring with Time Domain NIRS: A Review and Future Perspectives
MDPI, 2019Co-Authors: Lange FAbstract:Near-infrared spectroscopy (NIRS) is an optical technique that can measure brain tissue oxygenation and haemodynamics in real-time and at the patient bedside allowing medical doctors to access important physiological information. However, despite this, the use of NIRS in a clinical environment is hindered due to limitations, such as poor reproducibility, lack of depth sensitivity and poor brain-specificity. Time domain NIRS (or TD-NIRS) can resolve these issues and offer detailed information of the optical properties of the tissue, allowing better physiological information to be retrieved. This is achieved at the cost of increased instrument complexity, operation complexity and price. In this review, we focus on brain monitoring clinical applications of TD-NIRS. A total of 52 publications were identified, spanning the fields of neonatal imaging, stroke assessment, traumatic brain injury (TBI) assessment, brain death assessment, psychiatry, Peroperative Care, neuronal disorders assessment and communication with patient with locked-in syndrome. In all the publications, the advantages of the TD-NIRS measurement to (1) extract absolute values of haemoglobin concentration and tissue oxygen saturation, (2) assess the reduced scattering coefficient, and (3) separate between extra-cerebral and cerebral tissues, are highlighted; and emphasize the utility of TD-NIRS in a clinical context. In the last sections of this review, we explore the recent developments of TD-NIRS, in terms of instrumentation and methodologies that might impact and broaden its use in the hospital
B. Andreoni - One of the best experts on this subject based on the ideXlab platform.
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A consecutive series of 107 hepatic resections without mortality
'Springer Fachmedien Wiesbaden GmbH', 2003Co-Authors: A. Chiappa, R. Biffi, F. Luca, E. Bertani, A.p. Zbar, C. Crotti, U. Pace, M. Bellomi, B. AndreoniAbstract:Aims: A consecutive series of 107 hepatectomies was analyzed in order to identify relevant risk factors for significant postoperative complications. Methods: Amongst the 107 patients operated on between April 1996 and November 2002 at a single institution, there were 54 males and 53 females (mean age: 60 years\ub110 years; range: 27-79 years). Sixty-nine patients (64%) had metastases from colorectal cancer, 15 (14%) had primary hepatocellular carcinoma (HCC) and 18 patients (17%) had a range of other malignancies requiring resection. Five patients (5%) were resected for benign disease. A comparative study of significant postoperative complications following hepatectomy was conducted for the different patient groups. Results: There were several major postoperative complications observed, including bile leakage in 5 patients (5%), severe hepatic failure in 1 patient (1%), pneumonia in 2 patients (2%), peritonitis secondary to anastomotic dehiscence following concomitant bowel resection in 4 patients (4%) and pulmonary embolism in one patient (1%). There was no Peroperative mortality. The median postoperative hospital stay was 12 days (range: 6-140 days). Conclusions: Formal hepatic resection is a safe procedure providing that patients are well selected. The Peroperative Care of these cases appears to have a greater impact on outcome then either the type of resection or the pre-existing liver function
A. Chiappa - One of the best experts on this subject based on the ideXlab platform.
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A consecutive series of 107 hepatic resections without mortality
'Springer Fachmedien Wiesbaden GmbH', 2003Co-Authors: A. Chiappa, R. Biffi, F. Luca, E. Bertani, A.p. Zbar, C. Crotti, U. Pace, M. Bellomi, B. AndreoniAbstract:Aims: A consecutive series of 107 hepatectomies was analyzed in order to identify relevant risk factors for significant postoperative complications. Methods: Amongst the 107 patients operated on between April 1996 and November 2002 at a single institution, there were 54 males and 53 females (mean age: 60 years\ub110 years; range: 27-79 years). Sixty-nine patients (64%) had metastases from colorectal cancer, 15 (14%) had primary hepatocellular carcinoma (HCC) and 18 patients (17%) had a range of other malignancies requiring resection. Five patients (5%) were resected for benign disease. A comparative study of significant postoperative complications following hepatectomy was conducted for the different patient groups. Results: There were several major postoperative complications observed, including bile leakage in 5 patients (5%), severe hepatic failure in 1 patient (1%), pneumonia in 2 patients (2%), peritonitis secondary to anastomotic dehiscence following concomitant bowel resection in 4 patients (4%) and pulmonary embolism in one patient (1%). There was no Peroperative mortality. The median postoperative hospital stay was 12 days (range: 6-140 days). Conclusions: Formal hepatic resection is a safe procedure providing that patients are well selected. The Peroperative Care of these cases appears to have a greater impact on outcome then either the type of resection or the pre-existing liver function