Persistent Pain

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Francis J. Keefe - One of the best experts on this subject based on the ideXlab platform.

  • virtual reality for Persistent Pain a new direction for behavioral Pain management
    Pain, 2012
    Co-Authors: Francis J. Keefe, Dane A Huling, Michael J Coggins, Daniel F Keefe, Zachary M Rosenthal, Nathaniel R Herr, Hunter G Hoffman
    Abstract:

    Recent research indicates that immersive virtual reality (VR) can be used tool in treating acute Pain [10,25,23]. For example, VR-based behavioral interventions have been used to decrease acute Pain among individuals undergoing Painful medical procedures (e.g. wound cleaning of burn injuries [14,15,22,10], urological endoscopies (36)), physical therapy (e.g. for blunt force trauma [16], for burned skin [12,13]), and dental Pain [11,5], and experimental Pain in healthy volunteers (e.g. thermal Pain) [17,18]. Although these data suggest that VR has promise as a tool to help reduce acute Pain, there has been limited investigation on the use of VR in the treatment of patients with Persistent Pain. The purpose of this topical review is to identify and highlight ways in which VR can be used either alone or in combination with other treatments for Persistent Pain. The review is divided into three parts. First, we briefly describe VR methods currently used in the management of acute Pain. Second, we discuss several potential applications of VR as a behavioral intervention for Persistent Pain. Third, we highlight important future directions for research in this area.

  • Yoga for Persistent Pain: new findings and directions for an ancient practice.
    Pain, 2011
    Co-Authors: Anava A. Wren, Melissa A. Wright, James W. Carson, Francis J. Keefe
    Abstract:

    Currently, many clinicians treating Persistent Pain hear about the benefits of yoga from patients who frequent yoga centers. However, Pain clinicians and researchers may not be aware of randomized controlled studies examining the efficacy of yoga for managing Persistent Pain. The purpose of this review is to highlight recent studies that shed light on the potential role that yoga can play in Pain management for a range of conditions that can be chronically Painful. The review is divided into three sections: 1) a description of the basic components of yoga-based protocols for Pain, b) a review of nine of the thirteen randomized studies located that test yoga’s efficacy for Persistent Pain, and c) a discussion of key clinical issues and future directions for yoga-based Pain research and practice.

  • Applying Centrality of Event to Persistent Pain: A Preliminary View
    The Journal of Pain, 2007
    Co-Authors: Lisacaitlin M. Perri, Francis J. Keefe
    Abstract:

    Abstract Living with Persistent Pain is a complex experience. Based on clinical observations, Persistent Pain is often described as a stressful life event that has significantly altered how patients view themselves and the world around them. The Centrality of Event Scale (CES) assesses how much a stressful life event serves as a turning point in the individual's life, forms a reference point for personal identity, and affects the attribution of meaning to other life experiences. In this study, 47 patients with Persistent Pain were asked to complete the CES using "the experience of Persistent Pain" as the designated stressful life event. Data analyses revealed patients scoring high on the CES (ie, those who viewed Persistent Pain as a central life event) were significantly more likely to experience higher levels of Pain intensity ( r = .35, P = .02), life interference due to Pain ( r = .50, P = .002), and psychological distress ( r = .46, P = .001). Additional analyses revealed that the CES was a significant predictor of life interference due to Pain and psychological distress even after controlling for the effects of age, sex, education, and Pain intensity. Perspective The experience of Persistent Pain can serve as a major turning point in patients' lives, affect patients' interpretations of other life events, and become a key component of patients' identities. The results of this study indicate that centrality of event, a relatively new construct, could improve our understanding of Persistent Pain.

  • Psychological aspects of Persistent Pain: current state of the science ☆
    The Journal of Pain, 2004
    Co-Authors: Francis J. Keefe, Meredith E. Rumble, Cindy D. Scipio, Louis A. Giordano, Lisacaitlin M. Perri
    Abstract:

    Abstract This article provides an overview of current research on psychological aspects of Persistent Pain. It is divided into 3 sections. In section 1, recent studies are reviewed that provide evidence that psychological factors are related to adjustment to Persistent Pain. This section addresses research on factors associated with increased Pain and poorer adjustment to Pain (ie, Pain catastrophizing, Pain-related anxiety and fear of Pain, and helplessness) and factors associated with decreased Pain and improved adjustment to Pain (ie, self-efficacy, Pain coping strategies, readiness to change, and acceptance). In section 2, we review recent research on behavioral and psychosocial interventions for patients with Persistent Pain. Topics addressed include early intervention, tailoring treatment, telephone/Internet-based treatment, caregiver-assisted treatment, and exposure-based protocols. In section 3, we conclude with a general discussion that highlights steps needed to advance this area of research including developing more comprehensive and integrative conceptual models, increasing attention to the social context of Pain, examining the link of psychological factors to Pain-related brain activation patterns, and investigating the mechanisms underlying the efficacy of psychological treatments for Pain. Perspective This is one of several invited commentaries to appear in The Journal of Pain in recognition of The Decade of Pain Research. This article provides an overview of current research on psychological aspects of Persistent Pain, and highlights steps needed to advance this area of research.

  • psychological aspects of Persistent Pain current state of the science
    The Journal of Pain, 2004
    Co-Authors: Francis J. Keefe, Meredith E. Rumble, Cindy D. Scipio, Louis A. Giordano, Lisacaitlin M. Perri
    Abstract:

    Abstract This article provides an overview of current research on psychological aspects of Persistent Pain. It is divided into 3 sections. In section 1, recent studies are reviewed that provide evidence that psychological factors are related to adjustment to Persistent Pain. This section addresses research on factors associated with increased Pain and poorer adjustment to Pain (ie, Pain catastrophizing, Pain-related anxiety and fear of Pain, and helplessness) and factors associated with decreased Pain and improved adjustment to Pain (ie, self-efficacy, Pain coping strategies, readiness to change, and acceptance). In section 2, we review recent research on behavioral and psychosocial interventions for patients with Persistent Pain. Topics addressed include early intervention, tailoring treatment, telephone/Internet-based treatment, caregiver-assisted treatment, and exposure-based protocols. In section 3, we conclude with a general discussion that highlights steps needed to advance this area of research including developing more comprehensive and integrative conceptual models, increasing attention to the social context of Pain, examining the link of psychological factors to Pain-related brain activation patterns, and investigating the mechanisms underlying the efficacy of psychological treatments for Pain. Perspective This is one of several invited commentaries to appear in The Journal of Pain in recognition of The Decade of Pain Research. This article provides an overview of current research on psychological aspects of Persistent Pain, and highlights steps needed to advance this area of research.

Lisacaitlin M. Perri - One of the best experts on this subject based on the ideXlab platform.

  • Applying Centrality of Event to Persistent Pain: A Preliminary View
    The Journal of Pain, 2007
    Co-Authors: Lisacaitlin M. Perri, Francis J. Keefe
    Abstract:

    Abstract Living with Persistent Pain is a complex experience. Based on clinical observations, Persistent Pain is often described as a stressful life event that has significantly altered how patients view themselves and the world around them. The Centrality of Event Scale (CES) assesses how much a stressful life event serves as a turning point in the individual's life, forms a reference point for personal identity, and affects the attribution of meaning to other life experiences. In this study, 47 patients with Persistent Pain were asked to complete the CES using "the experience of Persistent Pain" as the designated stressful life event. Data analyses revealed patients scoring high on the CES (ie, those who viewed Persistent Pain as a central life event) were significantly more likely to experience higher levels of Pain intensity ( r = .35, P = .02), life interference due to Pain ( r = .50, P = .002), and psychological distress ( r = .46, P = .001). Additional analyses revealed that the CES was a significant predictor of life interference due to Pain and psychological distress even after controlling for the effects of age, sex, education, and Pain intensity. Perspective The experience of Persistent Pain can serve as a major turning point in patients' lives, affect patients' interpretations of other life events, and become a key component of patients' identities. The results of this study indicate that centrality of event, a relatively new construct, could improve our understanding of Persistent Pain.

  • Psychological aspects of Persistent Pain: current state of the science ☆
    The Journal of Pain, 2004
    Co-Authors: Francis J. Keefe, Meredith E. Rumble, Cindy D. Scipio, Louis A. Giordano, Lisacaitlin M. Perri
    Abstract:

    Abstract This article provides an overview of current research on psychological aspects of Persistent Pain. It is divided into 3 sections. In section 1, recent studies are reviewed that provide evidence that psychological factors are related to adjustment to Persistent Pain. This section addresses research on factors associated with increased Pain and poorer adjustment to Pain (ie, Pain catastrophizing, Pain-related anxiety and fear of Pain, and helplessness) and factors associated with decreased Pain and improved adjustment to Pain (ie, self-efficacy, Pain coping strategies, readiness to change, and acceptance). In section 2, we review recent research on behavioral and psychosocial interventions for patients with Persistent Pain. Topics addressed include early intervention, tailoring treatment, telephone/Internet-based treatment, caregiver-assisted treatment, and exposure-based protocols. In section 3, we conclude with a general discussion that highlights steps needed to advance this area of research including developing more comprehensive and integrative conceptual models, increasing attention to the social context of Pain, examining the link of psychological factors to Pain-related brain activation patterns, and investigating the mechanisms underlying the efficacy of psychological treatments for Pain. Perspective This is one of several invited commentaries to appear in The Journal of Pain in recognition of The Decade of Pain Research. This article provides an overview of current research on psychological aspects of Persistent Pain, and highlights steps needed to advance this area of research.

  • psychological aspects of Persistent Pain current state of the science
    The Journal of Pain, 2004
    Co-Authors: Francis J. Keefe, Meredith E. Rumble, Cindy D. Scipio, Louis A. Giordano, Lisacaitlin M. Perri
    Abstract:

    Abstract This article provides an overview of current research on psychological aspects of Persistent Pain. It is divided into 3 sections. In section 1, recent studies are reviewed that provide evidence that psychological factors are related to adjustment to Persistent Pain. This section addresses research on factors associated with increased Pain and poorer adjustment to Pain (ie, Pain catastrophizing, Pain-related anxiety and fear of Pain, and helplessness) and factors associated with decreased Pain and improved adjustment to Pain (ie, self-efficacy, Pain coping strategies, readiness to change, and acceptance). In section 2, we review recent research on behavioral and psychosocial interventions for patients with Persistent Pain. Topics addressed include early intervention, tailoring treatment, telephone/Internet-based treatment, caregiver-assisted treatment, and exposure-based protocols. In section 3, we conclude with a general discussion that highlights steps needed to advance this area of research including developing more comprehensive and integrative conceptual models, increasing attention to the social context of Pain, examining the link of psychological factors to Pain-related brain activation patterns, and investigating the mechanisms underlying the efficacy of psychological treatments for Pain. Perspective This is one of several invited commentaries to appear in The Journal of Pain in recognition of The Decade of Pain Research. This article provides an overview of current research on psychological aspects of Persistent Pain, and highlights steps needed to advance this area of research.

Joel Katz - One of the best experts on this subject based on the ideXlab platform.

  • systematic review of Persistent Pain and psychological outcomes following traumatic musculoskeletal injury
    Journal of Pain Research, 2013
    Co-Authors: Brittany N Rosenbloom, Colin J L Mccartney, Sobia Khan, Joel Katz
    Abstract:

    BACKGROUND: Persistent Pain and psychological distress are common after traumatic musculoskeletal injury (TMsI). Individuals sustaining a TMsI are often young, do not recover quickly, and place a large economic burden on society. OBJECTIVES: The aim of this systematic review is to determine (1) the incidence of Persistent Pain following TMsI, (2) the characteristics of Pain, characterized by injury severity and type, and (3) risk and protective factors associated with Persistent Pain following TMsI. METHODS: A systematic search of electronic databases (MEDLINE(®), PubMed(®), Embase, and PsycINFO(®)) was conducted for prospective, interventional, or noninterventional studies measuring the incidence of Pain associated with TMsI. RESULTS: The search revealed 4388 studies. Eleven studies examined Persistent Pain and met inclusion criteria. Pain was assessed using a validated measure of Pain intensity or Pain presence in six studies. Persistent Pain was reported by all studies at variable time points up to 84 months postinjury, with wide variation among studies in Pain intensity (ie, from mild to very severe) and Pain incidence at each time point. The incidence of Pain decreased over time within each study. Two studies found significant relationships between injury severity and Persistent Pain. Frequently cited predictive factors for Persistent Pain included: symptoms of anxiety and depression, patient perception that the injury was attributable to external sources (ie, they were not at fault), cognitive avoidance of distressing thoughts, alcohol consumption prior to trauma, lower educational status, being injured at work, eligibility for compensation, Pain at initial assessment, and older age. CONCLUSION AND IMPLICATIONS: The evidence from the eleven studies included in this review indicates that Persistent Pain is prevalent up to 84 months following traumatic injury. Further research is needed to better evaluate Persistent Pain and other long-term posttraumatic outcomes. Language: en

  • What exactly is central to the role of central neuroplasticity in Persistent Pain
    Behavioral and Brain Sciences, 1997
    Co-Authors: Terence J. Coderre, Joel Katz
    Abstract:

    The commentaries on our target article have raised important issues about central neuroplasticity and its role in Persistent Pain states. Some suggest that central neuroplasticity plays nothing more than a minor role in Persistent Pain, while others argue that Persistent Pain depends critically on peripheral inputs for its maintenance. Some stress that Persistent Pain relies to a large extent on changes in the brain and on centrifugal inputs from brain to spinal cord, whereas others argue that it depends on alterations in inhibitory as well as excitatory systems. We attempt to address each of the commentators' points, while defending our position that central neuroplasticity is critical to pathological Persistent Pain states.

  • Peripheral and central hyperexcitability: differential signs and symptoms in Persistent Pain.
    Behavioral and Brain Sciences, 1997
    Co-Authors: Terence J. Coderre, Joel Katz
    Abstract:

    This target article examines the clinical and experimental evidence for a role of peripheral and central hyperexcitability in Persistent Pain in four key areas: cutaneous hyperalgesia, referred Pain, neuropathic Pain, and postoperative Pain. Each suggests that Persistent Pain depends not only on central sensitization, but also on inputs from damaged peripheral tissue. It is instructive to think of central sensitization as comprised of both an initial central sensitization and an ongoing central sensitization driven by inputs from peripheral sources. Each of these factors, initial sensitization, ongoing central sensitization, and inputs from peripheral sources, contributes to the net activity in dorsal horn neurons and thus influences the expression of Persistent Pain or hyperalgesia. Since each factor, peripheral inputs and central sensitization (initial or ongoing), can contribute to both the initiation and maintenance of Persistent Pain, therapies should target both peripheral and central sources of pathology.

J Dinnen - One of the best experts on this subject based on the ideXlab platform.

  • assessment of acute and Persistent Pain management in patients with haemophilia
    Haemophilia, 2011
    Co-Authors: Michelle Witkop, A Lambing, E Kachalsky, G Divine, D Rushlow, J Dinnen
    Abstract:

    Summary.  A descriptive survey was conducted in Region V-E of the United States to bridge the gap in available information on Pain issues in the bleeding disorders population. The aim of this study was to a) determine language used by patients to describe and differentiate acute and Persistent Pain, b) describe pharmacological and non-pharmacological strategies utilized to control Pain, c) determine the providers of Pain management to this population and d) evaluate quality of life incorporating the SF-36 QOL tool. A total of 202 surveys were returned. For the purposes of this paper, it was decided to analyse only haemophilia data (n = 114). Average Persistent daily Pain levels were 5/10 (P < 0.001). The three most common word descriptors for both acute and Persistent Pain were the same - achy, throbbing and tender; the most utilized Pain medications were NSAIDs and acetaminophen. Factor replacement was used for what respondents described as acute Pain management 79% of the time and for Persistent Pain management 38% of the time. Participants described acute and Persistent Pain with the same Pain descriptors leading to the conclusion that patients have difficulty distinguishing between acute and Persistent Pain. This lack of differentiation was further displayed by the use of factor replacement to treat Persistent Pain associated with arthritic discomfort (38%) which would be viewed as inappropriate, as well as lack of factor replacement use by 21% of respondents who identified Pain as from an acute bleed. Opportunities exist to improve Pain management through patient and provider-directed educational programs.

Brittany N Rosenbloom - One of the best experts on this subject based on the ideXlab platform.

  • systematic review of Persistent Pain and psychological outcomes following traumatic musculoskeletal injury
    Journal of Pain Research, 2013
    Co-Authors: Brittany N Rosenbloom, Colin J L Mccartney, Sobia Khan, Joel Katz
    Abstract:

    BACKGROUND: Persistent Pain and psychological distress are common after traumatic musculoskeletal injury (TMsI). Individuals sustaining a TMsI are often young, do not recover quickly, and place a large economic burden on society. OBJECTIVES: The aim of this systematic review is to determine (1) the incidence of Persistent Pain following TMsI, (2) the characteristics of Pain, characterized by injury severity and type, and (3) risk and protective factors associated with Persistent Pain following TMsI. METHODS: A systematic search of electronic databases (MEDLINE(®), PubMed(®), Embase, and PsycINFO(®)) was conducted for prospective, interventional, or noninterventional studies measuring the incidence of Pain associated with TMsI. RESULTS: The search revealed 4388 studies. Eleven studies examined Persistent Pain and met inclusion criteria. Pain was assessed using a validated measure of Pain intensity or Pain presence in six studies. Persistent Pain was reported by all studies at variable time points up to 84 months postinjury, with wide variation among studies in Pain intensity (ie, from mild to very severe) and Pain incidence at each time point. The incidence of Pain decreased over time within each study. Two studies found significant relationships between injury severity and Persistent Pain. Frequently cited predictive factors for Persistent Pain included: symptoms of anxiety and depression, patient perception that the injury was attributable to external sources (ie, they were not at fault), cognitive avoidance of distressing thoughts, alcohol consumption prior to trauma, lower educational status, being injured at work, eligibility for compensation, Pain at initial assessment, and older age. CONCLUSION AND IMPLICATIONS: The evidence from the eleven studies included in this review indicates that Persistent Pain is prevalent up to 84 months following traumatic injury. Further research is needed to better evaluate Persistent Pain and other long-term posttraumatic outcomes. Language: en