The Experts below are selected from a list of 16734 Experts worldwide ranked by ideXlab platform
Santosh B. Mhaske - One of the best experts on this subject based on the ideXlab platform.
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transition metal free regioselective one pot synthesis of aryl sulfones from sodium sulfinates via quinone imine ketal
Journal of Organic Chemistry, 2019Co-Authors: Priyanka Halder, Vivek T. Humne, Santosh B. MhaskeAbstract:A novel, efficient, and regioselective transition-metal-free one-pot synthesis of aryl sulfones via the reactive quinone imine ketal intermediate is demonstrated using easily accessible bench-stable sulfinate salts. A broad range of functionality on p-anisidine substrates as well as sulfinate salts was tolerated under mild reaction conditions to provide the corresponding aryl sulfones in good to excellent yields.
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Transition-Metal-Free Regioselective One-Pot Synthesis of Aryl Sulfones from Sodium Sulfinates via Quinone Imine Ketal
2019Co-Authors: Priyanka Halder, Vivek T. Humne, Santosh B. MhaskeAbstract:A novel, efficient, and regioselective transition-metal-free one-pot synthesis of aryl sulfones via the reactive quinone imine ketal intermediate is demonstrated using easily accessible bench-stable sulfinate salts. A broad range of functionality on p-anisidine substrates as well as sulfinate salts was tolerated under mild reaction conditions to provide the corresponding aryl sulfones in good to excellent yields
Priyanka Halder - One of the best experts on this subject based on the ideXlab platform.
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transition metal free regioselective one pot synthesis of aryl sulfones from sodium sulfinates via quinone imine ketal
Journal of Organic Chemistry, 2019Co-Authors: Priyanka Halder, Vivek T. Humne, Santosh B. MhaskeAbstract:A novel, efficient, and regioselective transition-metal-free one-pot synthesis of aryl sulfones via the reactive quinone imine ketal intermediate is demonstrated using easily accessible bench-stable sulfinate salts. A broad range of functionality on p-anisidine substrates as well as sulfinate salts was tolerated under mild reaction conditions to provide the corresponding aryl sulfones in good to excellent yields.
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Transition-Metal-Free Regioselective One-Pot Synthesis of Aryl Sulfones from Sodium Sulfinates via Quinone Imine Ketal
2019Co-Authors: Priyanka Halder, Vivek T. Humne, Santosh B. MhaskeAbstract:A novel, efficient, and regioselective transition-metal-free one-pot synthesis of aryl sulfones via the reactive quinone imine ketal intermediate is demonstrated using easily accessible bench-stable sulfinate salts. A broad range of functionality on p-anisidine substrates as well as sulfinate salts was tolerated under mild reaction conditions to provide the corresponding aryl sulfones in good to excellent yields
Angela Hay - One of the best experts on this subject based on the ideXlab platform.
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The role of APetalA1 in Petal number robustness.
eLife, 2018Co-Authors: Marie Monniaux, Bjorn Pieper, Sarah M. Mckim, Daniel Kierzkowski, Richard S. Smith, Anne-lise Routier-kierzkowska, Angela HayAbstract:Invariant floral forms are important for reproductive success and robust to natural perturbations. Petal number, for example, is invariant in Arabidopsis thaliana flowers. However, Petal number varies in the closely related species Cardamine hirsuta, and the genetic basis for this difference between species is unknown. Here we show that divergence in the pleiotropic floral regulator APetalA1 (AP1) can account for the species-specific difference in Petal number robustness. This large effect of AP1 is explained by epistatic interactions: A. thaliana AP1 confers robustness by masking the phenotypic expression of quantitative trait loci controlling Petal number in C. hirsuta. We show that C. hirsuta AP1 fails to complement this function of A. thaliana AP1, conferring variable Petal number, and that upstream regulatory regions of AP1 contribute to this divergence. Moreover, variable Petal number is maintained in C. hirsuta despite sufficient standing genetic variation in natural accessions to produce plants with four-Petalled flowers.
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The genetic architecture of Petal number in Cardamine hirsuta
The New phytologist, 2015Co-Authors: Bjorn Pieper, Marie Monniaux, Angela HayAbstract:Invariant Petal number is a characteristic of most flowers and is generally robust to genetic and environmental variation. We took advantage of the natural variation found in Cardamine hirsuta Petal number to investigate the genetic basis of this trait in a case where robustness was lost during evolution. We used quantitative trait locus (QTL) analysis to characterize the genetic architecture of Petal number. Αverage Petal number showed transgressive variation from zero to four Petals in five C. hirsuta mapping populations, and this variation was highly heritable. We detected 15 QTL at which allelic variation affected Petal number. The effects of these QTL were relatively small in comparison with alleles induced by mutagenesis, suggesting that natural selection may act to maintain Petal number within its variable range below four. Petal number showed a temporal trend during plant ageing, as did sepal trichome number, and multi-trait QTL analysis revealed that these age-dependent traits share a common genetic basis. Our results demonstrate that Petal number is determined by many genes of small effect, some of which are age-dependent, and suggests a mechanism of trait evolution via the release of cryptic variation.
Bjorn Pieper - One of the best experts on this subject based on the ideXlab platform.
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The role of APetalA1 in Petal number robustness.
eLife, 2018Co-Authors: Marie Monniaux, Bjorn Pieper, Sarah M. Mckim, Daniel Kierzkowski, Richard S. Smith, Anne-lise Routier-kierzkowska, Angela HayAbstract:Invariant floral forms are important for reproductive success and robust to natural perturbations. Petal number, for example, is invariant in Arabidopsis thaliana flowers. However, Petal number varies in the closely related species Cardamine hirsuta, and the genetic basis for this difference between species is unknown. Here we show that divergence in the pleiotropic floral regulator APetalA1 (AP1) can account for the species-specific difference in Petal number robustness. This large effect of AP1 is explained by epistatic interactions: A. thaliana AP1 confers robustness by masking the phenotypic expression of quantitative trait loci controlling Petal number in C. hirsuta. We show that C. hirsuta AP1 fails to complement this function of A. thaliana AP1, conferring variable Petal number, and that upstream regulatory regions of AP1 contribute to this divergence. Moreover, variable Petal number is maintained in C. hirsuta despite sufficient standing genetic variation in natural accessions to produce plants with four-Petalled flowers.
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The genetic architecture of Petal number in Cardamine hirsuta
The New phytologist, 2015Co-Authors: Bjorn Pieper, Marie Monniaux, Angela HayAbstract:Invariant Petal number is a characteristic of most flowers and is generally robust to genetic and environmental variation. We took advantage of the natural variation found in Cardamine hirsuta Petal number to investigate the genetic basis of this trait in a case where robustness was lost during evolution. We used quantitative trait locus (QTL) analysis to characterize the genetic architecture of Petal number. Αverage Petal number showed transgressive variation from zero to four Petals in five C. hirsuta mapping populations, and this variation was highly heritable. We detected 15 QTL at which allelic variation affected Petal number. The effects of these QTL were relatively small in comparison with alleles induced by mutagenesis, suggesting that natural selection may act to maintain Petal number within its variable range below four. Petal number showed a temporal trend during plant ageing, as did sepal trichome number, and multi-trait QTL analysis revealed that these age-dependent traits share a common genetic basis. Our results demonstrate that Petal number is determined by many genes of small effect, some of which are age-dependent, and suggests a mechanism of trait evolution via the release of cryptic variation.
Cai-zhong Jiang - One of the best experts on this subject based on the ideXlab platform.
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transcriptome profiling of Petal abscission zone and functional analysis of an aux iaa family gene rhiaa16 involved in Petal shedding in rose
Frontiers in Plant Science, 2016Co-Authors: Yuerong Gao, Cai-zhong Jiang, Chun Liu, Yue Liang, Zhangjun Fei, Junping GaoAbstract:Roses are one of the most important cut flowers among ornamental plants. Rose flower longevity is largely dependent on the timing of Petal shedding occurrence. To understand the molecular mechanism underlying Petal abscission in rose, we performed transcriptome profiling of the Petal abscission zone during Petal shedding using Illumina technology. We identified a total of 2592 differentially transcribed genes (DTGs) during rose Petal shedding. Gene ontology term enrichment and pathway analysis revealed that major biochemical pathways the DTGs were involved in included ethylene biosynthesis, starch degradation, superpathway of cytosolic glycolysis, pyruvate dehydrogenase and TCA cycle, photorespiration and the lactose degradation III pathway. This suggests that alterations in carbon metabolism are an important part of rose Petal abscission. Among these DTGs, approximately 150 genes putatively encoding transcription factors were identified in rose abscission zone. These included zinc finger, WRKY, ERF, and Aux/IAA gene families, suggesting that Petal abscission involves complex transcriptional reprogramming. Approximately 108 DTGs were related to hormone pathways, of which auxin and ethylene related DTGs were the largest groups including 52 and 41 genes, respectively. These also included 12 DTGs related to gibberellin and 6 DTGs in jasmonic acid pathway. Surprisingly, no DTGs involved in the biosynthesis/signaling of abscisic acid, cytokinin, brassinosteroid, and salicylic acid pathways were detected. Moreover, among DTGs related to auxin, we identified an Aux/IAA gene RhIAA16 that was up-regulated in response to Petal shedding. Down-regulation of RhIAA16 by virus-induced gene silencing in rose promoted Petal abscission, suggesting that RhIAA16 plays an important role in rose Petal abscission.
